- Publikační typ
- abstrakt z konference MeSH
- Publikační typ
- abstrakt z konference MeSH
- Publikační typ
- abstrakt z konference MeSH
- Publikační typ
- abstrakt z konference MeSH
Comparison of cell-wall-bound extracellular proteinases (CEPs) from Lactobacillus paracasei (LBP) ssp. paracasei natural isolates BGHN14, BGAR75 and BGAR76 with Lactococcus lactis (LCL) ssp. cremoris Wg2, in their action on alpha(S1)-, beta- and kappa-casein was done. The CEPs of LBP strains were able to degrade alpha(S1)- and beta-caseins and their caseinolytic specificity depended on the type of buffer used. These CEPs, compared with LCL Wg2, differ in four amino acid residues in small segments predicted to be involved in substrate binding. The most striking features of this comparison are the presence of Ala instead of Ser(329) and the presence of Thr instead of Asn(256) and Ala(299), in the subtilisin-like region of the CEP in LBP natural isolates. Additional conservative amino acid substitution Leu to Ile(364) was found.
- MeSH
- bakteriální geny genetika MeSH
- bakteriální proteiny genetika metabolismus MeSH
- cysteinové endopeptidasy genetika metabolismus MeSH
- financování organizované MeSH
- kaseiny metabolismus MeSH
- katalytická doména genetika MeSH
- Lactobacillus enzymologie genetika MeSH
- Lactococcus lactis enzymologie genetika MeSH
- potravinářská mikrobiologie MeSH
- substituce aminokyselin MeSH
- substrátová specifita MeSH
- subtilisin genetika MeSH
- sýr mikrobiologie MeSH
- Publikační typ
- srovnávací studie MeSH
The support of close persons is a protective factor in the suicide epidemiology. The aim of this paper is to determine if there are differences between epidemiological characteristics of the suicides committed by married people in relation to singles. METHODS: In order to determine epidemiological characteristics of suicide among married and single people in the southeastern Serbia 628 suicides committed from 1995 to 2002 among persons 20 years of age and over were analysed. To compare suicide rates between married and single persons chi2 test was performed. RESULTS: From 628 registered suicides, 188 were performed by women, and 440 by men. The average annual suicide rate among males was 24.1 per 100,000 and among females it was 9.9. The highest rates were among widowed (139.0) and divorced men (63.2). The highest risk factor for suicide was to be widowed (men: RR=8.35; women: RR=2.75). The suicide trend among women, both married and single has been declining, whilst among males it has been on significant increase. Seasonality of suicides, weekly and daily distribution had a small influence on the epidemiological characteristics of suicides. Married women committed more suicides by poisoning than single women (p=0.02). In both groups, the most frequent way is hanging. CONCLUSION: Though marital status plays important role in an increasing rates of suicide, time and the way of its happening, this role is not decisive. Single people are very vulnerable and the time and way of suicide show that their reasons are more serious than among married ones.
- MeSH
- dospělí MeSH
- incidence MeSH
- lidé středního věku MeSH
- lidé MeSH
- manželský stav MeSH
- mladý dospělý MeSH
- registrace MeSH
- roční období MeSH
- sebevražda statistika a číselné údaje trendy MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Geografické názvy
- Srbsko MeSH
- MeSH
- chromozomální aberace MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- lymfocyty cytologie izolace a purifikace ultrasonografie MeSH
- mikrojaderné testy MeSH
- radioterapie normy MeSH
- věkové faktory MeSH
- vztah dávky záření a odpovědi MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- Publikační typ
- srovnávací studie MeSH
