- MeSH
- Evoked Potentials MeSH
- Humans MeSH
- Spinal Cord innervation MeSH
- Cerebral Cortex MeSH
- Reflex analysis MeSH
- Hand innervation MeSH
- Check Tag
- Humans MeSH
206 s. ; 23 cm
- MeSH
- European Union MeSH
- Insurance, Health MeSH
- Geographicals
- Europe MeSH
- Conspectus
- Veřejné zdraví a hygiena
- NML Fields
- ekonomie, ekonomika, ekonomika zdravotnictví
- politologie, politika, zdravotní politika
- právo, zákonodárství
- NML Publication type
- studie
Dystonie je syndrom, tradičně charakterizovaný abnormálními a mimovolními silnými a protrahovanými svalovými kontrakcemi, které způsobují charakteristické postavem částí těla a/nebo končetin, je exacerbována snahou o volní pohyb, který potom působí přelévání aktivity do vzdálenějších svalů. Autoři ve svém sdělení shrnují současné poznatky o charakteristice dystonických onemocnění a uvádějí současná klasifikační schémata. Zároveň shrnují aktuáhiě diskutované názory na podstatu dystohické dyskinezy a její patofyziologický substrát a uvádějí v přehledu výsledky neurofyziologických pozorování, která tento inovovaný pohled na dystonii podporují (48 referencí).
Dystonia is a syndrome traditionally characterized by abnormal and involuntary intense and protracted muscular contractions which cause a typical position of parts of the body or extremities, which is exacerbated by an effort to produce a voluntary movement which then causes passage of activity to more remote muscles. The authors summarize in the submitted paper contemporary findings on the characteristics of dystonie diseases and present contemporary classification patterns. They summarize also views, discussed at present, pertaining to the background of dystonie dyskinesia and its pathoPbysiological substrate and give an account of results of neurophysiological observations which support this irmovated view on dystonia (48 references).
BACKGROUND: Patients with cervical dystonia (CD) present with an impaired performance of voluntary neck movements, which are usually slow and limited. We hypothesized that such abnormality could involve defective preparation for task execution. Therefore, we examined motor preparation in CD patients using the StartReact method. In this test, a startling auditory stimulus (SAS) is delivered unexpectedly at the time of the imperative signal (IS) in a reaction time task to cause a faster execution of the prepared motor programme. We expected that CD patients would show an abnormal StartReact phenomenon. METHODS: Fifteen CD patients and 15 age matched control subjects (CS) were asked to perform a rotational movement (RM) to either side as quick as possible immediately after IS perception (a low intensity electrical stimulus to the II finger). In randomly interspersed test trials (25%) a 130 dB SAS was delivered simultaneously with the IS. We recorded RMs in the horizontal plane with a high speed video camera (2.38 ms per frame) in synchronization with the IS. The RM kinematic-parameters (latency, velocity, duration and amplitude) were analyzed using video-editing software and screen protractor. Patients were asked to rate the difficulty of their RMs in a numerical rating scale. RESULTS: In control trials, CD patients executed slower RMs (repeated measures ANOVA, p<0.10(-5)), and reached a smaller final head position angle relative to the midline (p<0.05), than CS. In test trials, SAS improved all RMs in both groups (p<0.10(-14)). In addition, patients were more likely to reach beyond their baseline RM than CS (χ(2), p<0.001) and rated their performance better than in control trials (t-test, p<0.01). CONCLUSION: We found improvement of kinematic parameters and subjective perception of motor performance in CD patients with StartReact testing. Our results suggest that CD patients reach an adequate level of motor preparation before task execution.
- MeSH
- Acoustic Stimulation * MeSH
- Adult MeSH
- Electromyography MeSH
- Head Movements MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Psychomotor Performance * MeSH
- Reaction Time MeSH
- Aged MeSH
- Case-Control Studies MeSH
- Torticollis physiopathology MeSH
- Loudness Perception * MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
