The Trail Making Test (TMT) comprises two psychomotor tasks that measure a wide range of visual-perceptual and executive functions. The purpose of this study was to provide Czech normative data and to examine the relationship between derived TMT indices and demographic variables. The TMT was administered to 421 healthy adults. Two clinical groups (n = 126) were evaluated to investigate the clinical utility of the TMT-derived scores: amnestic mild cognitive impairment (n = 90) and Alzheimer's disease (n = 36). Statistical analyses showed that age and education, but not gender, were significantly associated with TMT completion times and derived scores. Of all the indices, only the TMT ratio score was insensitive to age. We present normative values for the Czech version of the TMT, providing a reference for measuring individual performance in native Czech speakers. Moreover, we found that accuracy on the TMT was improved with the attenuation of age.

Department of Neurology and Centre of Clinical Neuroscience 1st Faculty of Medicine and General University Hospital Prague Charles University Prague Prague Czech Republic

Citace poskytuje Crossref.org

Distinctive autophagy/mitophagy biomarker profiles in frontotemporal lobar degeneration and Alzheimer's disease

CSF neurogranin levels as a biomarker in Alzheimer's disease and frontotemporal lobar degeneration: a cross-sectional analysis

Alterations of human CSF and serum-based mitophagy biomarkers in the continuum of Alzheimer disease

Comparison of decline in different cognitive domain in patients with normal pressure hydrocephalus

Directed functional connectivity of the default-mode-network of young and older healthy subjects

Cortical and subcortical morphometric changes and their relation to cognitive impairment in isolated REM sleep behavior disorder

Directed functional connectivity of the sensorimotor system in young and older individuals

Cognitive Functions, Depressive and Anxiety Symptoms After One Year of CPAP Treatment in Obstructive Sleep Apnea

Moderating effect of cognitive reserve on brain integrity and cognitive performance

Attention impairment in motor functional neurological disorders: a neuropsychological study

Determining a Short Form Montreal Cognitive Assessment (s-MoCA) Czech Version: Validity in Mild Cognitive Impairment Parkinson's Disease and Cross-Cultural Comparison

The Uniform Data Set, Czech Version: Normative Data in Older Adults from an International Perspective

The Diagnostic Accuracy of Parkinson's Disease Mild Cognitive Impairment Battery Using the Movement Disorder Society Task Force Criteria

Cognitive impairment and structural brain changes in patients with clinically isolated syndrome at high risk for multiple sclerosis