- MeSH
- diagnostické zobrazování MeSH
- dítě MeSH
- lidé MeSH
- nemoci kochley diagnostické zobrazování klasifikace patologie MeSH
- nemoci ucha * diagnostické zobrazování klasifikace patologie MeSH
- nemoci vnitřního ucha diagnostické zobrazování klasifikace patologie MeSH
- vrozené vady diagnostické zobrazování klasifikace patologie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- Publikační typ
- přehledy MeSH
OBJECTIVE: Vestibular schwannoma surgery leads to acute unilateral vestibular loss. In some patients, however, the process of post-operatively initiated central compensation proceeds more rapidly than in others. This study aimed to evaluate post-operative vestibular function and correlate it with morphological findings of MRI scans. METHODS: The study included 29 patients who underwent surgery for vestibular schwannoma. Vestibular function was analysed post-operatively by video head impulse test (vHIT). Subjective symptoms were evaluated using validated questionnaires. All patients underwent MRI 3 months post-operatively, and the presence of the facial and vestibulocochlear nerves in the internal auditory canal was assessed. RESULTS: The vestibulo-ocular reflex gain measured by the vHIT correlated positively with audiological findings. Subjective perception of vestibular disorder did not correlate with objectively measured vestibular impairment or with MRI findings. CONCLUSIONS: After the resection of vestibular schwannoma, some patients may still have preserved vestibular function as measured by vHIT. The preserved function does not correlate with subjective symptoms. Patients with partially deteriorated vestibular function showed lower sensitivity to combined stimuli.
- MeSH
- lidé MeSH
- pulsní rotační test MeSH
- vestibulární aparát * MeSH
- vestibulární nemoci * MeSH
- vestibulární schwannom * MeSH
- vestibulookulární reflex fyziologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
INTRODUCTION: Currently, it is possible to preserve the auditory nerve in a large number of cases, but the preservation of the hearing itself is unpredictable. Apart from wait and scan strategy and stereoradiotherapy, hearing after vestibular schwannoma surgery is considered to remain stable even in long-term follow-up. MATERIALS AND METHODS: Twenty-eight patients had preserved hearing after retrosigmoid suboccipital microsurgery of the vestibular schwannoma between 2008 and 2014. A standard audiological protocol was performed together with an magnetic resonance imaging evaluation of the fluid content of the inner ear. RESULTS: The mean difference in pure-tone average between the direct and final postsurgical examination was 12.758 dB ( p = 2.5E - 06). The word recognition score deteriorated by 17.45% ( p = 0.03516). The mean American Academy of Otolaryngology-Head and Neck Surgery score on the second examination was 2.5, and that on the second examination was 3.111 ( p = 0.00483). There was no significant deterioration in the healthy ear.The signal intensity ratio in the basal turn of the cochlea increased by an average of 0.13 points ( p < 0.05).Patients with persistent tumor or nodular enhancement in the internal acoustic meatus deteriorated significantly in hearing according to the American Academy of Otolaryngology-Head and Neck Surgery scale compared with patients without any finding in the meatus ( p = 0.01299). CONCLUSIONS: There is a discrete but gradual deterioration of the hearing in the postoperative period. Hearing impairment is more pronounced in patients with a nodular process in the internal acoustic meatus, regardless of whether it is growth active. After surgery, the pathological content of the inner ear normalizes (evaluated on T2 magnetic resonance imaging sequences).
- MeSH
- kochlea MeSH
- lidé MeSH
- nedoslýchavost * etiologie MeSH
- retrospektivní studie MeSH
- sluch MeSH
- vestibulární schwannom * chirurgie MeSH
- vnitřní ucho * chirurgie MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
The aim of the present research has been to determine whether there is a relationship between brain abnormalities found on magnetic resonance imaging (MRI) and autistic psychopathology. A retrospective analysis covering a period between 1998 and 2015 included 489 children with autism (404 boys, 85 girls; average age 8.0 ± 4.2 years) who underwent an MRI of the brain. For clinical diagnosis of autism, the International Classification of Diseases, 10th revision (ICD-10), was used. Autistic psychopathology was evaluated by means of the Autism Diagnostic Interview - Revised. The Spearman nonparametric correlation analysis and chi-square test were used to examine the possible relationships between variables. The group of autistic children did not manifest a statistically significant correlation between the parameters examined on MRI and autistic psychopathology. A correlation between other cysts and repetitive behavior was significant only at trend level (P = 0.054). Gliosis of the brain was significantly more frequent in autistic children with mental retardation than in children without mental retardation (14.1% vs. 7.4%; P = 0.028). Nonmyelinated areas in the brain were significantly more frequent in autistic children with autistic regression than in children without autistic regression (29.9% vs. 15.7%; P = 0.008). Mental retardation was significantly more frequent in autistic children with autistic regression than in children without regression (73.2% vs. 52.5%; P = 0.002). Our research study did not reveal a statistically significant correlation of brain abnormalities on MRI with autistic psychopathology.
- MeSH
- autistická porucha patofyziologie patologie MeSH
- lidé MeSH
- mozek diagnostické zobrazování patologie MeSH
- psychopatologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- práce podpořená grantem MeSH
- Publikační typ
- abstrakt z konference MeSH
Nodulární fasciitida je poměrně vzácné benigní onemocnění postihující vazivovou tkáň, které může svým rychlým růstem a podobnostmi v histologickém obraze snadno imitovat maligní měkkotkáňové tumory. V kazuistice prezentujeme případ nodulární fasciitidy v oblasti tváře u 64letého muže. Diskutována je klinická symptomatologie, patofyziologie, diagnostika a léčba tohoto vzácného onemocnění.
Nodular fasciitis is a relatively rare benign disease affecting connective tissue which, due to its rapid growth and similarities in the histological finding, can easily mimic malignant soft-tissue tumors. In the case report we present a case of nodular fasciitis in the facial region of the 64-year-old man. Clinical symptomatology, pathophysiology, diagnostics and methods of treatment are discussed.
- Klíčová slova
- nodulární fasciitida, zygomatická oblast, Myh9-usp6,
- MeSH
- fasciitida * chirurgie genetika patologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory obličeje chirurgie genetika patologie MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
AIMS: The aim of our study was to assess the yield of routine brain magnetic resonance imaging (MRI) performed at our hospital as part of the diagnostic procedures focused on autism. METHODS: Our retrospective study involved children who had attended a diagnostic examination focused on autism and underwent brain MRIs between 1998-2015. The International Classification of Diseases, 10th edition was used to make clinical diagnoses. In 489 children (404 boys, 85 girls; mean age 8.0±4.2 years), a diagnosis of a pervasive developmental disorder was confirmed. Forty-five children, where the autism diagnosis was ruled out (but other psychiatric diagnoses found), served as a control group (36 boys, 9 girls; mean age 7.0±2.4 years). We can assume that in such a control group, brain abnormalities might occur at a higher frequency than in truly healthy children which would have the effect of reducing the difference between the groups. RESULTS: MRI pathologies were more common in the autistic (45.4 %) compared to the control group (31.8%) but the difference was significant only at the trend level (P=0.085). Hypoplasia of the corpus callosum (CC) was significantly more common in the autistic vs. the control group (13.7 vs. 0%; P=0.009). In contrast, nonmyelinated areas of white matter were significantly more common in controls (31.8 vs.17.3%; P=0.018). Differences in other parameters were not significant. CONCLUSION: The occurrence of CC hypoplasia on routine MRI scans could represent a "red flag" for suspicion of autism.
- MeSH
- autistická porucha diagnostické zobrazování MeSH
- dítě MeSH
- lidé MeSH
- magnetická rezonanční tomografie metody MeSH
- mladiství MeSH
- mozek diagnostické zobrazování patofyziologie MeSH
- poruchy autistického spektra diagnóza MeSH
- předškolní dítě MeSH
- retrospektivní studie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
Cíl: Přehled možností provedení MR u pacientů s implantovaným vagovým stimulátorem (vagal nerve stimulator; VNS) a způsob chirurgické explantace VNS odpovídající MR protokolu a umožňující následné vyšetření MR bez výrazných omezení. Soubor a metodika: MR vyšetření je možné provést i u pacientů s implantovaným VNS. Lze provést vyšetření hlavy a těla kaudálně od Th8. Musí však být použita pouze lokální radiofrekvenční cívka a před MR musí být generátor VNS přeprogramován. Pokud má pacient generátor a větší část elektrody explantovány, lze provést MR v oblasti celého těla jakýmkoliv MR nastavením. To platí pro situaci, kdy po explantaci zůstane nejvýše 2cm část elektrody - což odpovídá části elektrody na vagovém nervu s fixačními kotvičkami. Výsledky: Od června 2016 do června 2018 jsme explantovali VNS výše uvedeným způsobem u šesti pacientů. Pooperační průběh u všech pacientů byl bez významných komplikací. Pooperační kontrolu jsme provedli pomocí RTG krku a CT 3D zobrazení. Zobrazovací metody ukázaly ponechanou část elektrody na n. vagus ≤ 2 cm. Pooperačně pacienti neměli polykací obtíže, chrapot ani změnu hlasu. Čtyři pacienti následně po zhojení rány již podstoupili MR bez jakýchkoliv obtíží či komplikací. Závěr: Explantace VNS odpovídající MR protokolu s ponecháním části elektrody na n. vagus, tedy vynecháním kompletní preparace celé elektrody na nervu, snižuje riziko komplikací a zkracuje dobu operačního zákroku. Pacientovi můžeme následně bezpečně provádět MR celého těla bez omezení v běžných technických nastaveních.
Aim: An overview of MRI in patients with implanted vagal nerve stimulator (VNS) and the method of surgical explantation of VNS, reflecting the MRI protocol allowing the subsequent MRI examination without significant limitations. Patients and methods: MRI can also be safely performed in patients with the implanted VNS device. Head examination and body examination caudally from Th8 can be performed, but only local radiofrequency coils must be used. Before the MRI, the VNS system must be reprogrammed. If the patient has an explanted generator and the larger part of the electrode, the MRI of the entire body can be performed with any common MRI setting. This applies to a situation where after the explantation there is only a 2-cm part of the electrode left - corresponding to the portion of the electrode on the vagal nerve with fixation anchors. Results: From June 2016 to June 2018, we explanted a VNS with this approach in six patients. Post-operative course of all patients was without complications. Post-operative control was performed using neck X-ray and CT 3D imaging. Imaging methods showed that the remainder of the electrode on the vagal nerve electrode was ≤ 2 cm. Post-operatively, patients did not have swallowing difficulties, hoarseness or voice changes. Four patients have subsequently already undergone MRI without any difficulties or complications. Conclusion: Surgical explantation of VNS according to the MRI protocol, leaving part of the electrode on the vagal nerve and omitting the complete preparation of the entire electrode on the nerve, reduces the risk of complications and shortens the duration of the operation. The patient can afterwards safely undergo the MRI of the entire body without any limitations in normal technical settings.
