A simple colorimetric tube detector for the detection of 2-(dialkylamino)ethanethiols and V-series nerve agents in water and in aqueous solutions is proposed. The detector is based on the reaction of the compounds with a chromogenic Folin-Ciocalteu reagent yielding a blue coloured reduction product. The detection limit of 2-(dialkylamino)ethanethiols is 2.5 mg/l, measurement range up to 250 mg/l. The detection limit of the V (VX) agent is 10 mg/l. The method allows V agents and their precursors and hydrolysis products to be easily distinguished from G-series nerve agents.
- MeSH
- Chemical Warfare Agents * isolation & purification adverse effects MeSH
- Water Pollution, Chemical * analysis adverse effects MeSH
- Indicators and Reagents MeSH
- Colorimetry methods instrumentation utilization MeSH
- Humans MeSH
- Organothiophosphorus Compounds * isolation & purification MeSH
- Statistics as Topic MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
False drugs are unsafe products that are manufactured using incorrect, inactive, or harmful ingredients. These drugs are packaged and labeled to look like real trademark generic drugs to deceive the consumer. Chemical analysis is a crucial step in distinguishing original pharmaceutics and fakes. HPLC and MS analyses are standard methods for identification and quantitation of active ingredients and impurities. Thus they are often used to corroborate the results of less sophisticated methods such as colorimetry, TLC, GS, Raman, NIR, FTIR and NMR spectrometries. The analytical methods should be employed in forensic laboratories.
- MeSH
- Artemisinins * analysis classification MeSH
- Chemistry Techniques, Analytical * methods utilization MeSH
- Chromatography, Thin Layer methods utilization MeSH
- Chromatography, Gas methods utilization MeSH
- Drug Industry legislation & jurisprudence MeSH
- Mass Spectrometry methods trends utilization MeSH
- Phosphodiesterase Inhibitors * analysis MeSH
- Colorimetry methods utilization MeSH
- Drug Contamination * prevention & control legislation & jurisprudence MeSH
- Humans MeSH
- Magnetic Resonance Spectroscopy methods MeSH
- Counterfeit Drugs * analysis supply & distribution MeSH
- Spectrum Analysis, Raman methods MeSH
- Spectroscopy, Fourier Transform Infrared methods instrumentation utilization MeSH
- Chromatography, High Pressure Liquid methods utilization MeSH
- Check Tag
- Humans MeSH
- MeSH
- Acetylcholinesterase diagnostic use MeSH
- Biochemical Phenomena drug effects MeSH
- Cholinesterase Inhibitors diagnostic use MeSH
- Mass Spectrometry history instrumentation utilization MeSH
- Indoles diagnostic use MeSH
- Colorimetry methods instrumentation utilization MeSH
- Humans MeSH
- Organophosphates isolation & purification MeSH
- Pesticides isolation & purification MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
- MeSH
- Apoptosis radiation effects MeSH
- Chalcones pharmacology MeSH
- Electrophoresis, Agar Gel methods utilization MeSH
- Enzyme-Linked Immunosorbent Assay methods utilization MeSH
- Financing, Organized MeSH
- HeLa Cells drug effects MeSH
- Angiogenesis Inhibitors pharmacology MeSH
- Jurkat Cells drug effects MeSH
- Colorimetry methods utilization MeSH
- Humans MeSH
- Antineoplastic Agents pharmacology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Abstracts MeSH
- MeSH
- Brassica MeSH
- Financing, Organized MeSH
- Jurkat Cells drug effects MeSH
- Colorimetry methods utilization MeSH
- Humans MeSH
- Cell Line, Tumor drug effects MeSH
- Breast Neoplasms drug therapy MeSH
- Antineoplastic Agents pharmacology MeSH
- Spiro Compounds pharmacology MeSH
- Terpenes pharmacology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Abstracts MeSH
- Keywords
- Aquasteril,
- MeSH
- Chemical Actions and Uses MeSH
- Chlorine chemistry isolation & purification MeSH
- Water Purification methods standards MeSH
- Clinical Laboratory Techniques standards instrumentation utilization MeSH
- Colorimetry methods instrumentation utilization MeSH
- Humans MeSH
- Fresh Water chemistry MeSH
- Military Hygiene methods MeSH
- Check Tag
- Humans MeSH
- MeSH
- Amphotericin B immunology therapeutic use MeSH
- Biofilms growth & development drug effects MeSH
- Candida growth & development drug effects MeSH
- Endocarditis complications blood MeSH
- Research Support as Topic MeSH
- Cross Infection complications blood MeSH
- Itraconazole immunology therapeutic use MeSH
- Colorimetry methods utilization MeSH
- Humans MeSH
- Oxazines MeSH
- Triazoles immunology therapeutic use MeSH
- Check Tag
- Humans MeSH
- MeSH
- Allantoin * pharmacokinetics MeSH
- Antioxidants * MeSH
- Pharmacokinetics MeSH
- Colorimetry methods utilization MeSH
- Uric Acid * pharmacokinetics MeSH
- Humans MeSH
- Urea * analogs & derivatives pharmacokinetics MeSH
- Oxidative Stress MeSH
- Reactive Oxygen Species MeSH
- Respiratory Burst MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
- MeSH
- Cytotoxicity, Immunologic * MeSH
- Dimethyl Sulfoxide MeSH
- Antineoplastic Agents, Phytogenic MeSH
- Hydrangeaceae * metabolism MeSH
- Colorimetry methods utilization MeSH
- Humans MeSH
- Cell Proliferation drug effects MeSH
- Plant Extracts * toxicity MeSH
- Cell Line, Transformed drug effects MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
