With growing interest in monitoring the health status of a human has raised demands on measuring systems and devices. It is important to develop monitoring system with user friendly and comfortable interface. This applies not only to setup and control but also to wearing and manipulation. Therefore, the replacement of conventional metal, rubber and selfadhesive electrodes by electrodes with thin-film conductive layer is desirable. These electrodes combine good electrical properties altogether with comfortable wearability, ease of manipulation and low-cost fabrication. The indicated factors allow these electrodes to be used in commercial measuring systems and devices. Their applicability in long term measurements is subject to meeting additional requirements, such as chemical and mechanical resistance. Abrasion caused by rubbing the human skin during standard measurements might affect the functionality of the electrode. Four types of electrodes based on Au, ITO, Graphite filled polymer and PEDOT:PSS underwent series of testing of their abrasion resistance. A surface with specific roughness and pressure force was used. A change in amplitude of testing ECG signal was measured as a function of number of abrasion cycles for all electrodes.
This review summarizes and discusses electrophoretic methods for the fabrication deposited graphene and graphene-based structures. Graphenes are commonly dispersed in organic solvents or in water. Deposition procedures are performed mostly under constant voltage and deposition time seems to be an important parameter for influence prepared graphene structures. It was shown that electrophoretically deposited graphene layers have excellent properties suitable for electrochemical sensors and biosensors construction, e.g. high electrical conductivity and large surface area. Electrophoretic deposition enables also preparation of material which combines graphene with metal nanoparticles or polymers.
[Current trends in nucleic acid electrochemistry]
Electrochemistry could be a valuable tool in nucleic acids research by offering relatively inexpensive instrumentation, short assay times and high sensitivity. Interesting applications can be found in the literature, including detection of oncogenes or tumor suppressor genes, analysis of point mutations in DNA, or determination of viruses and bacteria. Moreover, new strategies are being developed for detection of microRNAs, or for analysis of DNA methylation, both important in carcinogenesis. These novel approaches usually involve the use of various electroactive labels, nanomaterials, enzymes or magnetic particles, rendering them more sensitive, selective and efficient. In addition, electrochemistry was applied also in studies of DNA damage and interactions with other molecules. Numerous chemicals damage DNA in such a way that they alters electrochemical properties of DNA itself, such as oxygen radicals, aromatic hydrocarbons, alkylating agents and pesticides. DNA-modified electrodes could thus serve as simple biosensors for detection of environmental pollutants as well as potential antitumor drugs.
- MeSH
- biomedicínský výzkum MeSH
- diagnostické techniky molekulární využití MeSH
- elektrochemické techniky * trendy MeSH
- elektrochemie * trendy MeSH
- elektrody využití MeSH
- hybridizace nukleových kyselin * MeSH
- lidé MeSH
- mikro RNA MeSH
- poškození DNA * MeSH
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- lidé MeSH
- Publikační typ
- práce podpořená grantem MeSH
The voltammetric behavior of 4-aminobenzoic acid (PABA) and its acetylated metabolite on glassy carbon, carbon fiber or carbon paste electrodes was investigated in an aqueous supporting electrolyte. 4-Aminohippuric acid (4-AHA), 4-acetamidobenzoic acid (4-AMB) and 4-acetamidohippuric acid (4-Ac-AHA) can be separated on a capillary carbon paste electrode in 0.1 M lithium perchlorate. The oxidation potentials of PABA, 4-AHA, 4-AMB and 4-Ac-AHA were 0.70, 0.88, 1.06 and 1.10 V on capillary CPE, respectively. The electrooxidation process is used for simultaneous quantitative determination of acetylated metabolites in urine.
This paper deals with the heart signal processing by the module of the bio-amplifi er of „CERBEROS“ project. Th e aim of this paper is to fi nd whether it is possible to reconstruct some of the channels of the 12-channel ECG measurement from the approached position of the electrodes, eventually to learn math functions and further to design how to prove the methods whether this reconstruction is or is not authentic.
- MeSH
- elektrody využití MeSH
- elektrokardiografie metody přístrojové vybavení trendy MeSH
- elektromagnetické jevy MeSH
- lidé MeSH
- matematické výpočty počítačové MeSH
- počítačové zpracování signálu přístrojové vybavení MeSH
- technologie lékařská metody přístrojové vybavení trendy MeSH
- telemetrie MeSH
- zobrazování dat využití MeSH
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- lidé MeSH
The aim of this article is to describe device for ECG measuring by using only 5 electrodes. Classical electrocardiograph used in medicine has 10 electrodes. Th is device provide full-value 12 – lead ECG for clinical investigation of cardiovascular diseases. New system with 5 electrodes will provide similar result with similar accuracy as classical ECG. Th at means full-value 12-lead ECG such as in case classical ECG. But the main diff erence is that new system has only 5 electrodes. Th e main benefi t of this system is that it is defi nitely more useful for portable and mobile embedded system.
- MeSH
- elektrody normy trendy využití MeSH
- elektrokardiografie ambulantní metody přístrojové vybavení MeSH
- elektrokardiografie metody přístrojové vybavení využití MeSH
- lidé MeSH
- matematické výpočty počítačové MeSH
- počítačové zpracování signálu přístrojové vybavení MeSH
- služby domácí péče trendy využití zásobování a distribuce MeSH
- telemedicína metody přístrojové vybavení trendy MeSH
- telemetrie metody přístrojové vybavení trendy MeSH
- urgentní zdravotnické služby trendy využití zásobování a distribuce MeSH
- Check Tag
- lidé MeSH
