BACKGROUND: Early life socioeconomic disadvantage and adverse experiences may lead to overeating, which is in turn associated with increased body mass index (BMI). However, recent evidence indicated that the association between childhood BMI and overeating might be bidirectional. This bidirectionality prompts the need for further investigation of early life predictors of BMI in childhood. OBJECTIVES: To longitudinally assess the directionality of the association between childhood BMI and perceived overeating and to investigate their antecedent early life predictors. METHODS: The sample included data from 5151 children from the ELSPAC study, collected between 18 months and 11 years of child age. The outcomes were child BMI and mother-reported overeating, assessed at the age of 3, 5, 7 and 11 years. Predictors included maternal BMI, maternal education, single parenthood, financial difficulties and adverse childhood experiences (ACEs) reported by parents and paediatricians. The random intercept cross-lagged panel model was applied. RESULTS: The mean child's BMI at age 3 was 15.59 kg/m2 and increased to 17.86 kg/m2 at age 11. The percentage of parent-reported overeating increased in the following period, from about 12% at age 3 to 17% at age 11. The results showed temporal stability in perceived overeating and BMI, with a bidirectional relationship strengthening over time. The child's BMI was associated with maternal BMI. Maternal BMI was positively associated with child-perceived overeating, but a stronger effect was found for ACEs. ACEs mediated the impact of maternal education, financial difficulties and single parenthood on overeating. CONCLUSIONS: We observed stable bidirectional associations between BMI and perceived overeating. The results indicated two main pathways: one linked to maternal BMI and early childhood BMI increase followed by perceived overeating and the second associated with ACEs mediating the effect of early childhood social factors on perceived overeating, leading to gradual BMI gain.
- MeSH
- dítě MeSH
- hyperfagie * psychologie epidemiologie MeSH
- index tělesné hmotnosti * MeSH
- kojenec MeSH
- lidé MeSH
- longitudinální studie MeSH
- matky psychologie statistika a číselné údaje MeSH
- nepříznivé zkušenosti z dětství * statistika a číselné údaje psychologie MeSH
- obezita dětí a dospívajících * epidemiologie psychologie MeSH
- předškolní dítě MeSH
- socioekonomické faktory MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Maternal alcohol consumption can adversely affect children's development, but the impact of paternal drinking is less understood. We aimed to investigate whether maternal or paternal alcohol consumption during pregnancy affected children's mental health and behavior. METHODS: A total of 2,013 parent-child triads from the European Longitudinal Study of Pregnancy and Childhood cohort were used. Data on alcohol consumption was obtained from questionnaires during pregnancy and after the child's birth. Mental health and behavior of children were assessed with Strength and Difficulties Questionnaire (SDQ). The associations were tested using linear regression, adjusting for socio-demographic and psychosocial covariates. RESULTS: Increased maternal alcohol consumption was associated with higher total SDQ scores at ages 7, 11, and 18 years old when the outcomes were reported by mothers, but only at 11 years when reported by children. We did not observe any dose-response relationship, and the effect size did not change during the follow-up. The effects were observed across various domains of SDQ: in the emotional symptoms subscale at age 11, in the conduct problems subscale at ages 7 and 11, and in the hyperactivity/inattention subscale at age 18. Paternal alcohol consumption was not associated with SDQ. CONCLUSIONS: Maternal alcohol consumption during pregnancy is associated with long-term effects on children's mental health and behavior, particularly when reported by mothers. No association was found between paternal alcohol consumption, suggesting that the results may stem from biological effects of alcohol or other factors beyond the direct exposure, potentially encompassing broader maternal psychosocial or behavioral characteristics.
- MeSH
- chování dětí * MeSH
- dítě MeSH
- dospělí MeSH
- lidé MeSH
- longitudinální studie MeSH
- matky * statistika a číselné údaje MeSH
- mladiství MeSH
- otcové * statistika a číselné údaje MeSH
- pití alkoholu * škodlivé účinky epidemiologie MeSH
- těhotenství MeSH
- zpožděný efekt prenatální expozice * epidemiologie MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Evropa MeSH
Non-invasive fetal electrocardiography appears to be one of the most promising fetal monitoring techniques during pregnancy and delivery nowadays. This method is based on recording electrical potentials produced by the fetal heart from the surface of the maternal abdomen. Unfortunately, in addition to the useful fetal electrocardiographic signal, there are other interference signals in the abdominal recording that need to be filtered. The biggest challenge in designing filtration methods is the suppression of the maternal electrocardiographic signal. This study focuses on the extraction of fetal electrocardiographic signal from abdominal recordings using a combination of independent component analysis, recursive least squares, and ensemble empirical mode decomposition. The method was tested on two databases, the Fetal Electrocardiograms, Direct and Abdominal with Reference Heartbeats Annotations and the PhysioNet Challenge 2013 database. The evaluation was performed by the assessment of the accuracy of fetal QRS complexes detection and the quality of fetal heart rate determination. The effectiveness of the method was measured by means of the statistical parameters as accuracy, sensitivity, positive predictive value, and F1-score. Using the proposed method, when testing on the Fetal Electrocardiograms, Direct and Abdominal with Reference Heartbeats Annotations database, accuracy higher than 80% was achieved for 11 out of 12 recordings with an average value of accuracy 92.75% [95% confidence interval: 91.19-93.88%], sensitivity 95.09% [95% confidence interval: 93.68-96.03%], positive predictive value 96.36% [95% confidence interval: 95.05-97.17%] and F1-score 95.69% [95% confidence interval: 94.83-96.35%]. When testing on the Physionet Challenge 2013 database, accuracy higher than 80% was achieved for 17 out of 25 recordings with an average value of accuracy 78.24% [95% confidence interval: 73.44-81.85%], sensitivity 81.79% [95% confidence interval: 76.59-85.43%], positive predictive value 87.16% [95% confidence interval: 81.95-90.35%] and F1-score 84.08% [95% confidence interval: 80.75-86.64%]. Moreover, the non-invasive ST segment analysis was carried out on the records from the Fetal Electrocardiograms, Direct and Abdominal with Reference Heartbeats Annotations database and achieved high accuracy in 7 from in total of 12 records (mean values μ < 0.1 and values of ±1.96σ < 0.1).
- MeSH
- algoritmy * MeSH
- břicho fyziologie MeSH
- databáze faktografické MeSH
- elektrokardiografie metody MeSH
- lidé MeSH
- matky statistika a číselné údaje MeSH
- monitorování plodu metody MeSH
- plod fyziologie MeSH
- počítačové zpracování signálu přístrojové vybavení MeSH
- srdeční frekvence plodu fyziologie MeSH
- těhotenství MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: Despite numerous efforts to improve maternal and child health in Malawi, maternal and newborn mortality rates remain very high, with the country having one of the highest maternal mortality ratios globally. The aim of this study was to identify which individual factors best predict utilisation of skilled maternal healthcare in a sample of women residing in Lilongwe district of Malawi. Identifying which of these factors play a significant role in determining utilisation of skilled maternal healthcare is required to inform policies and programming in the interest of achieving increased utilisation of skilled maternal healthcare in Malawi. METHODS: This study used secondary data from the Woman's Questionnaire of the 2010 Malawi Demographic and Health Survey (MDHS). Data was analysed from 1126 women aged between 15 and 49 living in Lilongwe. Multivariate logistic regression was conducted to determine significant predictors of maternal healthcare utilisation. RESULTS: Women's residence (P=.006), education (P=.004), and wealth (P=.018) were significant predictors of utilisation of maternal healthcare provided by a skilled attendant. Urban women were less likely (odds ratio [OR] = 0.47, P=.006, 95% CI = 0.28-0.81) to utilise a continuum of maternal healthcare from a skilled health attendant compared to rural women. Similarly, women with less education (OR = 0.32, P=.001, 95% CI = 0.16-0.64), and poor women (OR = 0.50, P=.04, 95% CI = 0.26-0.97) were less likely to use a continuum of maternal healthcare from a skilled health attendant. CONCLUSION: Policies and programmes should aim to increase utilisation of skilled maternal healthcare for women with less education and low-income status. Specifically, emphasis should be placed on promoting education and economic empowerment initiatives, and creating awareness about use of maternal healthcare services among girls, women and their respective communities.
- MeSH
- dítě MeSH
- dospělí MeSH
- dostupnost zdravotnických služeb statistika a číselné údaje MeSH
- kojenec MeSH
- lidé středního věku MeSH
- lidé MeSH
- logistické modely MeSH
- matky psychologie statistika a číselné údaje MeSH
- novorozenec MeSH
- odds ratio MeSH
- pacientův souhlas se zdravotní péčí psychologie statistika a číselné údaje MeSH
- předpověď MeSH
- předškolní dítě MeSH
- průzkumy a dotazníky MeSH
- služby zdravotní péče o dítě statistika a číselné údaje MeSH
- služby zdravotní péče o matku statistika a číselné údaje trendy MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- kojenec MeSH
- lidé středního věku MeSH
- lidé MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Malawi MeSH
OBJECTIVE: This study analyses the differences in birth outcomes between Roma and non-Roma mothers and investigates the potential causes of such differences. METHODS: We conducted a retrospective cohort study of 1,989 non-Roma and 799 Roma mothers who gave birth in 2014 and 2015 at the Gynaecology and Obstetrics Clinic of Louis Pasteur University Hospital in Košice. Data on mothers and new-born infants have been obtained from the birth book and from the reports on mothers at childbirth. For low birth weight we considered the weight of a new-born weighing less than 2,500 grams and as for premature birth we referred to childbirth before pregnancy week 37. The file was split by ethnicity and statistically processed in IBM SPSS Statistics 21.0. RESULTS: Our results confirmed a lower birth weight among Roma children (-365.4 grams, p < 0.001). The shorter gestation age and higher risk of premature birth were not statistically significant regarding Roma children. Based on the characteristics of Roma mothers, they are at higher risk of giving birth as minor (OR = 23.64; 95% CI = 15.29-36.54; p < 0.001), as single mothers (OR = 7.13; 95% CI = 5.80-8.76; p < 0.001), with basic education or lack of education (OR = 141.31; 95% CI = 100.47-198.76; p < 0.001). They also have a higher risk of smoking during pregnancy (OR = 23.84; 95% CI = 18.06-31.49; p < 0.001); drinking alcohol (OR = 11.71; 95% CI = 3.36-40.90; p < 0.001) and taking drugs (OR = 8.70; 95% CI = 1.81-42.02; p < 0.001). Roma women attended gynaecologists more rarely. CONCLUSION: It is therefore important to support the work of community health workers and stimulate collaboration between community health professionals, paediatricians and gynaecologists to overcome institutional barriers in maternity and child care for mothers living in Roma settlement.
- MeSH
- dospělí MeSH
- lidé MeSH
- matky statistika a číselné údaje MeSH
- novorozenec s nízkou porodní hmotností * MeSH
- novorozenec MeSH
- porodní hmotnost MeSH
- předčasný porod etnologie MeSH
- retrospektivní studie MeSH
- rizikové faktory MeSH
- Romové etnologie statistika a číselné údaje MeSH
- těhotenství MeSH
- výsledek těhotenství etnologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Slovenská republika MeSH
Highly prevalent and typically beginning in childhood, asthma is a burdensome disease, yet the risk factors for this condition are not clarified. To enhance understanding, this study assessed the cohort-specific and pooled risk of maternal education on asthma in children aged 3-8 across 10 European countries. Data on 47,099 children were obtained from prospective birth cohort studies across 10 European countries. We calculated cohort-specific prevalence difference in asthma outcomes using the relative index of inequality (RII) and slope index of inequality (SII). Results from all countries were pooled using random-effects meta-analysis procedures to obtain mean RII and SII scores at the European level. Final models were adjusted for child sex, smoking during pregnancy, parity, mother's age and ethnicity. The higher the score the greater the magnitude of relative (RII, reference 1) and absolute (SII, reference 0) inequity. The pooled RII estimate for asthma risk across all cohorts was 1.46 (95% CI 1.26, 1.71) and the pooled SII estimate was 1.90 (95% CI 0.26, 3.54). Of the countries examined, France, the United Kingdom and the Netherlands had the highest prevalence's of childhood asthma and the largest inequity in asthma risk. Smaller inverse associations were noted for all other countries except Italy, which presented contradictory scores, but with small effect sizes. Tests for heterogeneity yielded significant results for SII scores. Overall, offspring of mothers with a low level of education had an increased relative and absolute risk of asthma compared to offspring of high-educated mothers.
- MeSH
- bronchiální astma epidemiologie etiologie MeSH
- dítě MeSH
- lidé MeSH
- matky * psychologie statistika a číselné údaje MeSH
- předškolní dítě MeSH
- prevalence MeSH
- rizikové faktory MeSH
- srovnání kultur MeSH
- stupeň vzdělání * MeSH
- věk matky MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
- Geografické názvy
- Evropa epidemiologie MeSH
BACKGROUND: Comparable evidence on adiposity inequalities in early life is lacking across a range of European countries. This study investigates whether low maternal education is associated with overweight and obesity risk in children from distinct European settings during early childhood. METHODS: Prospective data of 45 413 children from 11 European cohorts were used. Children's height and weight obtained at ages 4-7 years were used to assess prevalent overweight and obesity according to the International Obesity Task Force definition. The Relative/Slope Indices of Inequality (RII/SII) were estimated within each cohort and by gender to investigate adiposity risk among children born to mothers with low education as compared to counterparts born to mothers with high education. Individual-data meta-analyses were conducted to obtain aggregate estimates and to assess heterogeneity between cohorts. RESULTS: Low maternal education yielded a substantial risk of early childhood adiposity across 11 European countries. Low maternal education yielded a mean risk ratio of 1.58 (95% confidence interval (CI) 1.34, 1.85) and a mean risk difference of 7.78% (5.34, 10.22) in early childhood overweight, respectively, measured by the RII and SII. Early childhood obesity risk by low maternal education was as substantial for all cohorts combined (RII = 2.61 (2.10, 3.23)) and (SII = 4.01% (3.14, 4.88)). Inequalities in early childhood adiposity were consistent among boys, but varied among girls in a few cohorts. CONCLUSIONS: Considerable inequalities in overweight and obesity are evident among European children in early life. Tackling early childhood adiposity is necessary to promote children's immediate health and well-being and throughout the life course.
- MeSH
- dospělí MeSH
- kojenec MeSH
- lidé MeSH
- mateřské chování * psychologie MeSH
- matky * psychologie statistika a číselné údaje MeSH
- novorozenec MeSH
- obezita dětí a dospívajících epidemiologie etiologie prevence a kontrola MeSH
- předškolní dítě MeSH
- prevalence MeSH
- prospektivní studie MeSH
- rizikové faktory MeSH
- socioekonomické faktory MeSH
- srovnání kultur MeSH
- stupeň vzdělání * MeSH
- těhotenství MeSH
- Check Tag
- dospělí MeSH
- kojenec MeSH
- lidé MeSH
- mužské pohlaví MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Evropa epidemiologie MeSH
BACKGROUND: A healthy start to life is a major priority in efforts to reduce health inequalities across Europe, with important implications for the health of future generations. There is limited combined evidence on inequalities in health among newborns across a range of European countries. METHODS: Prospective cohort data of 75 296 newborns from 12 European countries were used. Maternal education, preterm and small for gestational age births were determined at baseline along with covariate data. Regression models were estimated within each cohort and meta-analyses were conducted to compare and measure heterogeneity between cohorts. RESULTS: Mother's education was linked to an appreciable risk of preterm and small for gestational age (SGA) births across 12 European countries. The excess risk of preterm births associated with low maternal education was 1.48 (1.29 to 1.69) and 1.84 (0.99 to 2.69) in relative and absolute terms (Relative/Slope Index of Inequality, RII/SII) for all cohorts combined. Similar effects were found for SGA births, but absolute inequalities were greater, with an SII score of 3.64 (1.74 to 5.54). Inequalities at birth were strong in the Netherlands, the UK, Sweden and Spain and marginal in other countries studied. CONCLUSIONS: This study highlights the value of comparative cohort analysis to better understand the relationship between maternal education and markers of fetal growth in different settings across Europe.
- MeSH
- hypotrofický novorozenec * MeSH
- lidé MeSH
- lineární modely MeSH
- matky statistika a číselné údaje MeSH
- novorozenec MeSH
- předčasný porod epidemiologie MeSH
- prospektivní studie MeSH
- regresní analýza MeSH
- rizikové faktory MeSH
- srovnání kultur MeSH
- stupeň vzdělání MeSH
- těhotenství MeSH
- výsledek těhotenství epidemiologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- metaanalýza MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Evropa MeSH
OBJECTIVE: This study analyses the role of ethnicity-based birth weight differences at term (37-42 weeks) between neonates of Roma and non-Roma populations in Hungary, controlling for socio-demographic and biological characteristics of the mothers. METHODS: A cross-sectional survey among 9,040 mothers coupled with biometric data of the neonates was conducted in 2010. Inclusion criteria were: at term (37-42 weeks gestation) non-pathological pregnancies, and self-reported ethnicity. Birth weight was based on mothers' ethnicity, age, body mass index, education, marital and employment status, poverty level, household amenities, dietary and smoking habits using multiple linear regression. RESULTS: The mean difference between Roma and non-Roma neonates measured without controlling for possible confounding factors was -288.7 gram (p < 0.001, 95% CI = -313.4-263.9). In the linear regression model Roma neonates weighed on average 69.67 grams less than non-Roma neonates (p < 0.001, 95% CI = 30.51-108.83). The mother's underweight BMI, low education and smoking during pregnancy (p < 0.001), age under 18 years, no amenities of housing and insufficient consumption of fruits and dairy products also significantly influenced (p < 0.05) the neonates' birth weight. CONCLUSION: Roma ethnicity was independently correlated with lower birth-weight among at term neonates, controlling for known risk factors. Roma ethnicity may serve as a proxy for other unmeasured social or biological factors and should be considered an important covariate for measurement among neonates.
- MeSH
- chudoba etnologie MeSH
- index tělesné hmotnosti MeSH
- kouření etnologie MeSH
- lidé MeSH
- lineární modely MeSH
- manželský stav etnologie MeSH
- matky statistika a číselné údaje MeSH
- mladiství MeSH
- novorozenec MeSH
- porodní hmotnost * MeSH
- průřezové studie MeSH
- Romové statistika a číselné údaje MeSH
- stravovací zvyklosti etnologie MeSH
- těhotenství mladistvých etnologie MeSH
- těhotenství MeSH
- věk matky MeSH
- veřejné zdravotnictví * MeSH
- výsledek těhotenství etnologie MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Research Support, N.I.H., Extramural MeSH
- Geografické názvy
- Maďarsko MeSH
Studie se zabývá rozhodováním matek o vakcinaci svých dětí proti pneumokokovým nákazám. Danou otázku zkoumá pomocí kvantitativního on-line dotazníkového šetření (n=180) vycházejícího z teoretického rámce teorie plánovaného chování, již také aplikuje jako teoretický model formou logistické regrese. Teorie plánovaného chování se ukazuje jako dobrý prediktivní nástroj, přičemž nejvýznamnější determinantou záměru očkovat je postoj matek vůči očkování proti pneumokokům, jeden ze tří základních konstruktů teorie. Zbylé dva se jako vlivné neprojevily s určitostí (subjektivní norma) či vůbec (vnímaná kontrola chování). Jako vlivné se také ukazuje vnímání hrozby vedlejších účinků vakcíny, jedna z proměnných rozšiřujících původní teoretický model. Výsledky testovaných modelů podporují závěr, že postoj k očkování představuje základní determinantu rozhodnutí, a to zejména pro matky se záměrem neočkovat.
The study deals with the issue of mothers' decision-making regarding their child's vaccination against pneumococcal infections. An online survey of mothers (n = 180) was based on the theory of planned behaviour (TPB). A hierarchical logistic regression was used to test the theoretical model with the intention to vaccinate as the dependent variable. The theory proved itself as a strong predictive instrument. The results suggest that attitude is the main predictor of the decision. The subjective norm, as the second construct of the TPB, contributes only in certain cases and the perceived behavioural control was found to have no influence at all. The perception of vaccine-related contradictions is an important factor alongside that of attitude. These results support the idea that mothers, especially those who do not want to vaccinate their children against pneumococcal infections, primarily base their decision on their attitude.
- MeSH
- chování a mechanismy chování MeSH
- dítě * MeSH
- dospělí MeSH
- lidé MeSH
- matky * psychologie statistika a číselné údaje MeSH
- mladý dospělý MeSH
- nežádoucí účinky léčiv prevence a kontrola psychologie MeSH
- odmítnutí terapie pacientem * psychologie statistika a číselné údaje MeSH
- pneumokokové vakcíny * aplikace a dávkování škodlivé účinky terapeutické užití MeSH
- průzkumy a dotazníky MeSH
- statistika jako téma MeSH
- zohlednění rizika MeSH
- Check Tag
- dítě * MeSH
- dospělí MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH