... Purpose and principles of immunophenotyping -- A compendium of antibodies and the patterns of expression ... ... of the equivalent antigens in normal and neoplastic cells -- Immunophenotyping in the diagnosis and ...
x, 139 stran, ilustrace; 26 cm
- MeSH
- Hematologic Tests MeSH
- Immunophenotyping * MeSH
- Publication type
- Monograph MeSH
- Conspectus
- Patologie. Klinická medicína
- NML Fields
- hematologie a transfuzní lékařství
Imunofenotypizace je již dnes standardní metodou v diagnostice hemato-onkologických onemocnění. V současné době zažíváme rozvoj mnohobarevné průtokové cytometrie, jak ve výzkumu, tak i v klinické diagnostice. Práce shrnuje diagnostiku a sledování akutní lymfoblastické leukemie pomocí průtokové cytometrie.
Immunophenotyping is a standard method used in diagnostics of hematological malignancies. Progress in number of multicolour cytometry as well as new targets identified by genomics bring new possibilities in research and diagnostics. These aspects are summarized in the article.
- MeSH
- Precursor Cell Lymphoblastic Leukemia-Lymphoma diagnosis classification therapy MeSH
- Antigens, Differentiation, B-Lymphocyte classification MeSH
- Antigens, Differentiation, T-Lymphocyte classification MeSH
- Child MeSH
- Research Support as Topic MeSH
- Immunophenotyping methods utilization MeSH
- Humans MeSH
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma diagnosis physiopathology MeSH
- Flow Cytometry methods MeSH
- Neoplasm, Residual MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- MeSH
- Leukemia, Erythroblastic, Acute diagnosis MeSH
- Precursor Cell Lymphoblastic Leukemia-Lymphoma diagnosis MeSH
- Child MeSH
- Adult MeSH
- Immunophenotyping MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Flow Cytometry MeSH
- Aged MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Comparative Study MeSH
Best practice & research clinical haematology, ISSN 1521-6926 Vol. 23, no. 3, September 2010
S. 305-451 : il., tab.
- MeSH
- Immunophenotyping MeSH
- Blood Cells cytology MeSH
- Hematologic Diseases diagnosis MeSH
- Flow Cytometry MeSH
- Publication type
- Collected Work MeSH
- Conspectus
- Patologie. Klinická medicína
- NML Fields
- hematologie a transfuzní lékařství
- alergologie a imunologie
- MeSH
- Lymphocyte Activation MeSH
- B-Lymphocytes MeSH
- Chronic Disease MeSH
- Adult MeSH
- Immunophenotyping MeSH
- Middle Aged MeSH
- Humans MeSH
- Leukemia, Lymphoid diagnosis blood MeSH
- Antibodies, Monoclonal MeSH
- Biomarkers, Tumor MeSH
- Antibodies, Neoplasm analysis blood MeSH
- Aged MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Aged MeSH
Cytometric cellular analysis
1st ed. 442 s.
180 s. : il.
BACKGROUND: Flow cytometry is a method that enables the automated quantification of a set of parameters for a large number of cells or cell-like particles. It is also possible to analyze solid tissues after reduction to a single cell suspension. One of the applications of fl ow cytometry is immunophenotyping. AIM: The authors try to introduce the basic physical and biological principles of fl ow-cytometry to the broader public and to prove the benefits of method in lymph nodes assessment. METHOD: A common method of immunophenotyping with the help of labeled monoclonal antibodies applied to lymph node cells was used. RESULTS: Flow cytometry revealed the infiltration of the extirpated lymph node with leukemic cells. CONCLUSIONS: The authors demonstrate fl ow cytometry as a relatively less common but efficient way of lymph node assessment in a patient with an anamnesis of acute lymphoblastic leukemia. They also discuss the contribution of immunophenotyping to the process of the differential diagnostics of lymph nodes enlargement.
- MeSH
- Diagnosis, Differential MeSH
- Adult MeSH
- Immunophenotyping methods MeSH
- Leukemia diagnosis MeSH
- Humans MeSH
- Lymphatic Diseases diagnosis MeSH
- Lymph Nodes immunology pathology MeSH
- Flow Cytometry MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Research Support, Non-U.S. Gov't MeSH
Best practice & research clinical haematology, ISSN 1521-6926 Vol. 16, no. 4, December 2003
S. 545-683 : il., tab.
- MeSH
- Antigens MeSH
- Immunophenotyping MeSH
- Lymphoma MeSH
- Publication type
- Collected Work MeSH
- Conspectus
- Patologie. Klinická medicína
- NML Fields
- hematologie a transfuzní lékařství
- onkologie
