• MeSH
• fosfáty MeSH
• posmrtné změny metabolismus   MeSH
• svaly metabolismus   patofyziologie   MeSH
• zvířata MeSH
• Check Tag
• zvířata MeSH

• MeSH
• dospělí MeSH
• injekce MeSH
• lidé MeSH
• poranění míchy patologie   MeSH
• posmrtné změny MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH

• MeSH
• aceton krev   MeSH
• diabetes mellitus MeSH
• hyperglykemie MeSH
• krevní glukóza analýza   MeSH
• lidé MeSH
• posmrtné změny MeSH
• soudní lékařství metody   MeSH
• Check Tag
• lidé MeSH

• MeSH
• morbidita MeSH
• mortalita MeSH
• nemoc MeSH
• patologie MeSH
• pitva MeSH
• terminologie jako téma MeSH
• Geografické názvy
• Česká republika MeSH
• Slovenská republika MeSH

In forensic assessment, denial and concealment of pregnancy has wide-ranging implications including criminal abortions, extramural deliveries, concealment of birth, newborn infant abandonment or even neonaticide. Clarification of whether a newborn was born alive is the most important factor when evaluating an abandoned neonate or concealment of birth. Other points that need to be addressed are determination of viability and maturity of the newborn infant, and the identity of the mother. A prolonged postmortem interval following illegal disposal of a dead body often leads to advanced decomposition, making postmortem elucidation difficult. We report an exceptionally uncommon autopsy case of a well-preserved female newborn, which was accidentally found after eight years in a home freezer. Despite the prolonged postmortem interval, tissue preservation was sufficient for a meaningful autopsy including a comprehensive histopathological study. The purpose of the present investigations was to expand our understanding of thanatological processes, as well as detectability of particular histological findings on the remains of a newborn after extremely prolonged storage in an artificially frozen environment. In addition, this article discusses forensically important issues regarding concealment of newborn infant under specific conditions.

• MeSH
• asfyxie novorozenců diagnóza   MeSH
• imunohistochemie MeSH
• lidé MeSH
• novorozenec MeSH
• pitva metody   MeSH
• posmrtné změny MeSH
• příčina smrti MeSH
• syndrom aspirace mekonia diagnóza   MeSH
• zmrazování * MeSH
• Check Tag
• lidé MeSH
• novorozenec MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH

• MeSH
• hmyz MeSH
• posmrtné změny MeSH

We measured the length of the pyramidal neurons in the cortical layer III in four subregions of the planum temporale (transitions into superior temporal gyrus, Heschl's gyrus, insular cortex, and Sylvian fissure) in control group and Alzheimer disease patients. Our hypothesis was that overall length of the pyramidal neurons would be smaller in the Alzheimer disease group compared to controls and also there would be right-left asymmetry in both the control and Alzheimer disease groups. We found pyramidal neuron length asymmetry only in controls--in the transition into the Sylvian fissure--and the rest of the subregions in the control group and Alzheimer disease patients did not show size difference. However, control-Alzheimer disease group pyramidal neuron length comparison revealed (a) no length difference in superior temporal gyrus transition area, (b) reversal of asymmetry in the insular transition area with left insular transition significantly shorter in the Alzheimer disease group compared to the control group, (c) both right and left Heschl's gyrus transitions significantly shorter in the Alzheimer disease group compared to the control group, and (d) right Sylvian fissure transition significantly shorter in the Alzheimer disease group compared to the control group. This neuronal length measurement method could supplement already existing neuropathological criteria for postmortem Alzheimer disease diagnostics.

• MeSH
• Alzheimerova nemoc patologie   MeSH
• lidé MeSH
• posmrtné změny MeSH
• pyramidové buňky patologie   MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• srovnávací studie MeSH

Endocan is a soluble molecule secreted from vascular endothelial cells of various organs. Its exact function in humans remains to be elucidated, though it has been postulated that increased tissue expression or serum levels of this molecule may be an indicator of endothelial activation and neovascularization. In the realm of forensic pathology, studies pertaining to endothelial activation following exposure to cold exclusively focused on thrombomodulin, a transmembrane protein specific to endothelial cells. In the study herein described, endocan concentrations were determined in postmortem serum, urine and vitreous humor samples collected during autopsy in a series of cases that underwent medicolegal investigations. A total of 76 autopsy cases were selected and three study groups (hypothermia group, sepsis group and non-hypothermia/non-sepsis group) prospectively formed during the study period. The obtained results seem to indicate that exposure to cold and subsequent death is not distinguished by significant endothelial dysfunction causing enhanced endocan secretion.

• MeSH
• biologické markery metabolismus   MeSH
• dospělí MeSH
• hypotermie diagnóza   metabolismus   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• nádorové proteiny metabolismus   MeSH
• posmrtné změny MeSH
• prospektivní studie MeSH
• proteoglykany metabolismus   MeSH
• senioři MeSH
• sklivec metabolismus   MeSH
• soudní patologie MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

• MeSH
• časové faktory MeSH
• muskuloskeletální a nervový systém - fyziologické jevy MeSH
• posmrtné změny patofyziologie   diagnóza   MeSH
• tělesná teplota MeSH

• Konspekt
• Lékařské vědy. Lékařství
• NLK Obory
• soudní lékařství
• fyziologie

Autori vykonali forenznú expertízu 6 mŕtvych tiel osôb násilne usmrtených v súvislosti s aktivitami organizovaného zločinu. Všetky mŕtvoly boli po smrti zabalené do vriec či materiálov z umelých hmôt (plasty) a uložené ilegálne do zeme na vopred pripravených miestach. Pri detailnej prehliadke a pitve týchto tiel sa ukázalo, že posmrtné kadaverózne zmeny vďaka takmer nepriedušného utesneniu mŕtvol v plastových materiáloch prebiehali ináč a podstatne pomalšie v porovnaní s telami zomrelých, uložených do zeme v štandardných rakvách. Autori poukazujú na niektoré osobitnosti takto prebiehajúcich posmrtných rozkladných procesov a problémy s presnejším určením času smrti jedinca.

The forensic expertise of the 6 human bodies, being murdered in organised crime activities, had been realised by the authors. All the cadavers were packed in plastic bags or plastic foils, then buried to the illegal graves, being prepared in advance. The detail overlook and autopsy of the bodies had disclosed, that due of almost airtight sealing of the cadavers in plastic materials, the postmortal cadaverous changes went on much slower and were manifested under a different picture, as seen in the human cadavers being buried in the standard wooden coffins. The authors point out the peculiarities of such a postmortal changes, with particular focusing on the estimation of postmortal period.

• MeSH
• anaerobióza MeSH
• exhumace MeSH
• lidé MeSH
• pitva MeSH
• posmrtné změny MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• kazuistiky MeSH