OBJECTIVE: Acetabular fractures can lead to serious complications such as avascular necrosis of the femoral head (AVN), osteoarthritis, non-union. Total hip replacement (THR) is a treatment option for these complications. The purpose of this study was to assess the functional and radiological outcomes of THR at least 5 years after the primary implantation. METHODS: This retrospective study analysed clinical data from 77 patients (59 males, 18 females) who were treated from 2001 to 2022. Data was collected on the incidence of AVN of the femoral head, complications, interval from fracture to THR, reimplantation. The modified Harris Hip Score (MHHS) was used to evaluate outcome. RESULTS: The mean age at the time of fracture was 48 years. Avascular necrosis developed in 56 patients (73%), with 3 cases of non-union. Osteoarthritis without AVN developed in 20 patients (26%), non-union without AVN in one patient (1%). The mean time from fracture to THR was 24 months for AVN with non-union, 23 months for AVN alone, 22 months for AVN with arthritis, 49 months for hip osteoarthritis without AVN. The time interval was significantly shorter for cases of AVN than for cases of osteoarthritis without AVN (p = 0.0074). Type C1 acetabular fracture was found to be a risk factor for femoral head AVN (p = 0.0053). Common complications of acetabular fractures included post-traumatic sciatic nerve paresis (17%), deep venous thrombosis (4%), infections (4%). Hip dislocation was the most common complication of THR (17%). There were no cases of thrombosis following THR. According to Kaplan-Meier analysis, the proportion of patients without revision surgery within 10-year period was 87.4% (95% CI 86.7-88.1). The results of the MHHS after THR: 59.3% of patients had excellent results, 7.4% good, 9.3% satisfactory results, and 24.0% had poor results. The mean MHHS was 84 points (95% CI 78.5-89.5). Paraarticular ossifications were observed in 69.4% of patients in the radiological evaluation. CONCLUSION: Total hip replacement is an effective treatment for serious complications of acetabular fracture treatment. Its results are comparable to THR peformed for other indications, although it is associated with a higher number of paraarticular ossifications. Type C1 acetabular fracture was found to be a significant risk factor for early femoral head AVN.
- MeSH
- acetabulum diagnostické zobrazování chirurgie zranění MeSH
- artróza kyčelních kloubů * diagnostické zobrazování etiologie chirurgie MeSH
- fraktury kyčle * chirurgie MeSH
- fraktury páteře * chirurgie MeSH
- lidé středního věku MeSH
- lidé MeSH
- náhrada kyčelního kloubu * škodlivé účinky MeSH
- osteonekróza * MeSH
- retrospektivní studie MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
PURPOSE: Pelvic ring fractures requiring surgical stabilization are severe injuries. Surgical site infections occurring after stabilization of the pelvis are serious complications, requiring complex and multidisciplinary treatment. METHODS: This is a retrospective observational study from a level I trauma centre. One hundred and ninety-two patients who underwent stabilization of closed pelvic ring injuries without signs of pathological fracture were selected for inclusion into the study. After excluding seven patients for having incomplete data, the final study group consisted of 185 patients (117 men and 68 women). Basic epidemiologic data and potential risk factors were recorded and analyzed by Cox regression, Kaplan-Meier curves, and risk ratios in 2 × 2 tables. Categorical variables were compared by Fisher exact tests and chi squared tests. Parametric variables were analyzed with Kruskal-Wallis tests with post hoc Wilcoxon tests. RESULTS: Surgical site infections occurred in 13% of the study group (24 from 185). Eighteen infections occurred in men (15.4%) and six in women (8.8%). There were two significant risk factors in women: age over 50 years (p = 0.0232) and concomitant urogenital trauma (p = 0.0104). The common risk ratio for both these factors was 212.59 (8.78-5148.68), p = 0.0010. No significant risk factors were identified in men despite younger men having a higher incidence of infection (p = 0.1428). CONCLUSION: Overall rate of infectious complications was higher than in the literature, but this might be caused by inclusion of all patients regardless of surgical strategy. Higher age in women and lower age in men were associated with higher infection rates. Concomitant urogenital trauma was a significant risk factor in women.
- MeSH
- fixace fraktury škodlivé účinky MeSH
- fraktury kostí * epidemiologie chirurgie komplikace MeSH
- infekce chirurgické rány epidemiologie etiologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- pánevní kosti * chirurgie zranění MeSH
- pozorovací studie jako téma MeSH
- retrospektivní studie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- metaanalýza MeSH
- práce podpořená grantem MeSH
A 13-year-old girl suffered fracture of her left clavicle. A figure-of-8 bandage was placed during initial treatment. Six days after trauma her distal arm, elbow and proximal forearm were swollen, pain and tenderness of distal part of brachial vein was recognized during clinical examination. Duplex ultrasonography revealed partial thrombosis of the brachial vein. Bandage was immediately removed and administration of LMWH (enoxaparin) was started. Complete recanalization was achieved after a few days. The fracture was healed without further complication, patient was without sonographic and clinical signs of post-thrombotic syndrome. The second case report describes a 14-year-old boy. Initially, the fixation was a figure-of-8 bandage. 5 days after the injury he had swollen arm and elbow on the injured side, according to duplex ultrasonography deep venous thrombosis of the axillary and the brachial vein was recognized. There was only partial recanalization at the first sonographic follow up, the patient was converted to Warfarin for 3 months after injury after initial LMWH therapy. At the last follow-up, fracture of the left clavicle was healed and there were no DUSG or clinical signs of post-thrombotic syndrome. Key words: clavicle, deep venous thrombosis of the upper extremity, anticoagulant therapy.
- MeSH
- COVID-19 * komplikace MeSH
- dítě MeSH
- fraktury kostí * komplikace terapie MeSH
- heparin nízkomolekulární terapeutické užití MeSH
- klíční kost diagnostické zobrazování zranění MeSH
- konzervativní terapie škodlivé účinky MeSH
- lidé MeSH
- mladiství MeSH
- žilní trombóza * diagnostické zobrazování farmakoterapie etiologie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
PURPOSE OF THE STUDY Vertically unstable transforaminal sacral fractures can be stabilized with several types of transiliac internal fixators (TIFI): the classical one (TIFI-C), the supraacetabular one (TIFI-A) and by dual application of TIFI (DTIFI). MATERIAL AND METHODS Pelvic models made of solid foam (Sawbones 1301) were used in the study. Mechanical loading tests were performed in order to assess the stiffness of the studied pelvic structures. The stiffness of the intact model was approximated as the slope of load/displacement curve. Then vertically unstable right-sided linear transforaminal fracture was created and subsequently fixed by TIFI-C, TIFI-A and DTIFI (each fixator for a separate model). The fixation techniques were compared based on the ratio between the stiffness of the treated and of the intact pelvis. Motion of the posterior pelvic structures and their deformations were measured using a photogrammetric system with four synchronous cameras. Loads applied at the base of sacrum and sacral base displacements were recorded by the testing device and used to assess the stiffness of the model structure. A dedicated load cell and a monoaxial extensometer were utilised. Every measurement was repeated at least 10 times. Obtained data were analysed by one way ANOVA test with post hoc comparison by Tukey HSD test. RESULTS Mean stiffness ratio (±1SD) of pelvic structure was 0.638 ± 0.005 for TIFI-C, 0.722 ± 0.014 for TIFI-A and 0.720 ± 0.008 for DTIFI. Dual transiliac internal fixation and supraacetabular fixation were superior to the classical one (p < 0.0001), but DTIFI and TIFI-A stiffness ratios were statistically equivalent (p = 0.9112). CONCLUSIONS Results of the mechanical analysis using pelvic models indicate that for linear vertical transforaminal sacral fracture without comminuted zone, an application of either TIFI-A or DTIFI provides significantly higher stiffness of the lateral pelvic segment than application of TIFI-C. Key words: transforaminal sacral fracture, transiliac internal fixator, dual TIFI, stability, biomechanics, digital image correlation.
- MeSH
- biomechanika MeSH
- fraktury kostí * MeSH
- interní fixátory MeSH
- kostní šrouby MeSH
- křížová kost chirurgie MeSH
- lidé MeSH
- mechanické testy MeSH
- pánev MeSH
- pánevní kosti * diagnostické zobrazování chirurgie MeSH
- vnitřní fixace fraktury MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
AIM OF THE STUDY: Epidemiologic evaluation of pelvic ring injuries in children. METHODS: Retrospective analysis over a period of 13 years, excluding pathological fractures. AO/OTA type, epidemiological data, type of treatment, and complications were recorded. Data were assessed using Fisher's exact test and Wilcoxon test. RESULTS: 243 boys, 115 girls, mean age (SD) 14.1 ± 3.0 years, AO/OTA types: 281 A, 52 B, 25 C. Multiple trauma: 62, combined trauma: 59, mono-trauma: 237. 281 patients were treated non-operatively, 97 surgically. ETIOLOGY: traffic accidents 88, falls from a great height 37, crushing injuries four, and sports injuries 192, simple falls 30, others seven. High-energy mechanisms prevailed in types B and C. Low-energy mechanism in type A (p < 0.0001). Similar differences were found between type A (p = 0.0009) and in case type C requiring surgery and cases treated non-operatively (p < 0.0001). Twenty-six patients (7.3%) had complications (pelvic asymmetry 5, neurological deficits 5, non-union 1, ectopic calcification 4, others 7). Higher complication rates were associated with types B and C (p = 0.0015), with surgically treated cases (p < 0.0001) and multiple trauma (p = 0.0305). DISCUSSION: Results of this trial were comparable with other studies. CONCLUSION: Sports injuries accounted for most type A injuries, while types B and C tended to be associated with high-energy trauma. Complications were associated with the severity of pelvic trauma, more common in surgically treated group of patients; this is primarily linked to the surgical cases being more serious as well as the associated injuries.
- MeSH
- dítě MeSH
- fraktury kostí * epidemiologie chirurgie MeSH
- lidé MeSH
- mladiství MeSH
- pánevní kosti * zranění chirurgie MeSH
- polytrauma * MeSH
- retrospektivní studie MeSH
- traumatologická centra MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Heparin-induced thrombocytopenia is a rare complication of treatment with both unfractionated heparin (UFH) and low molecular weight heparin (LMWH). Antibodies against the complex heparin-platelet factor 4 are the main cause of pathogenesis, resulting in the activation of thrombocytes, coagulation, endothelium, monocytes, neutrophils and subsequent highly prothrombotic state. The prothrombotic state can result not only in venous but also in arterial thrombosis at different locations (which is manifested apart from venous thromboembolic disease also by acute limb ischemia, acute myocardial infarction, ischemic stroke, skin necrotizing lesion exanthema). If HIT is not adequately treated, it may be fatal in up to 10% of patients. For early diagnosis, a combination of 4T scores and diagnostic lab tests for HIT is required. Immediate discontinuation of heparin therapy (UFH, LMWH) and switching to non-heparin anticoagulants (fondaparinux, bivalirudin, argatroban or in some situations DOACs) are essential in HIT treatment. The case report describes the patient after primary knee replacement, complicated by the development of HIT with no evidence of venous thromboembolic disease. Preoperatively, the patient was administrated nadroparin due to paroxysmal atrial fibrillation, after the development of HIT, anticoagulation was modified to fondaparinux and subsequently to warfarin after the platelet count normalization. Key words: unfractioned heparin, low molecular weight heparin, thrombocytopenia, total knee replacement.
- MeSH
- antikoagulancia škodlivé účinky MeSH
- heparin škodlivé účinky MeSH
- lidé MeSH
- totální endoprotéza kolene * MeSH
- trombocytopenie chemicky indukované diagnóza terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- MeSH
- antikoagulancia škodlivé účinky terapeutické užití MeSH
- diferenciální diagnóza MeSH
- inhibitory faktoru Xa aplikace a dávkování MeSH
- lidé MeSH
- nadroparin * aplikace a dávkování škodlivé účinky MeSH
- perioperační péče MeSH
- senioři MeSH
- totální endoprotéza kolene MeSH
- trombocytopenie farmakoterapie chemicky indukované klasifikace MeSH
- trombofilie epidemiologie farmakoterapie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- kazuistiky MeSH
- práce podpořená grantem MeSH
