BACKGROUND AND OBJECTIVE: The prevalence of pelvic floor muscle injuries induced by childbirth is higher than 23 % in the general women population. Such injuries can lead to prolapses and other pathologies in future female life. Leveraging computational biomechanics, the study implements an advanced female pelvic floor model for computing the maximum pelvic muscle strain, which serves as an injury risk indicator. The design of experiment method, abbreviated as DoE, is used to compute the maximum strain for boundary values of bony pelvis dimensions, namely the anterior-posterior diameter (abbreviated as APD) and the transverse diameter (abbreviated as TD). This is done in combination with small, medium and large percentiles of fetal head circumference (abbreviated as HC). METHODS: We utilized a previously developed finite element model of a female pelvic floor, as a reference, and enhanced it with new features, including a more detailed tissue geometry and advanced constitutive material models. The APD and TD dimensions were sourced from the set of MRI of 64 nulliparous women. This data was used to estimate the boundary dimensions of the female bony pelvis, combining both small and large values of APD and TD. Together with the 10th and the 95th percentiles for HC, a three-dimensional domain was constructed to assess the maximum pelvic muscle strain. In boundary cases, the maximum pelvic muscle strain was computed across 8 full-factorial design models (each situated at one corner of the domain, thereby combining the minimum and the maximum values of APD, TD and HC). This was done to define a response surface that predicts the maximum pelvic muscle strain within the domain. The accuracy of this response surface prediction was validated using 15 additional intermediate design models. These models were placed at the center of the domain (1 point), the centres of the domain boundary surfaces (6 points), and midway along each domain boundary edge (8 points). RESULTS: The maximum strain results for 8 combinations of APD, TD, and HC were employed to construct a linear response surface as a function of APD, TD, and HC. Tests at an additional 19 domain points served to evaluate the efficiency of the response surface prediction. The response surface demonstrated strong predictability, with an absolute average error of 1.52 %, an absolute median error of 1.52 %, and an absolute maximum error of 11.11 %. HC emerged as the most influencing dimension, accounting for 16 % of influence. CONCLUSIONS: The reference finite element pelvic floor model was scaled to 8 full-factorial female-specific pelvic floor models, which represent the combination of boundary values for APD, TD, and HC. The maximum pelvic floor muscle strain from these 8 models was used to design a response surface. When implementing the DoE approach to construct the response, there was consistent predictability for the maximum perineal muscle strain, as validated by the additional 19 intermediate design models. As a result, the response surface methodology can serve as an initial predictor for potential childbirth-induced pelvic floor muscle injury.
- MeSH
- kosterní svaly diagnostické zobrazování MeSH
- lidé MeSH
- magnetická rezonanční tomografie MeSH
- pánevní dno diagnostické zobrazování fyziologie MeSH
- porod * fyziologie MeSH
- těhotenství MeSH
- vedení porodu * MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
OBJECTIVE: The perineal body connects muscles from the pelvic floor and is critical for support of the lower part of the vagina and proper function of the anal canal. We determined mechanical parameters and volume fractions of main components of the human female postmenopausal perineal body. METHODS: The specimens were taken from 15 fresh female cadavers (age 74 ± 10, mean ± standard deviation). Seventy-five specimens from five regions of the perineal body were processed histologically to assess volume fractions of tissue components using stereological point testing grid. Fifteen specimens taken from the midline region were loaded uniaxially with 6 mm/min velocity until tissue rupture to determine Young's modulus of elasticity, ultimate stresses, and strains. RESULTS: The perineal body was composed of collagen (29%), adipose cells (27%), elastin (7%), smooth muscle (11%), and skeletal muscle (3%). The residual tissue (19%) constituted mostly peripheral nerves, lumina of blood vessels, fibroblasts, and fibrocytes. Young's modulus of elasticity at midline region was 18 kPa (median) at small and 232 kPa at large deformations, respectively. The ultimate stress was 172 kPa and the ultimate strain was 1.4. CONCLUSIONS: We determined the structural and mechanical parameters of the perineal body. The resultant data could be used as input for models simulating pelvic floor prolapse or dysfunction.
- MeSH
- anální kanál MeSH
- biomechanika fyziologie MeSH
- elastin analýza MeSH
- hladké svalstvo anatomie a histologie MeSH
- kolagen analýza MeSH
- kosterní svaly anatomie a histologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mrtvola MeSH
- pánevní dno anatomie a histologie fyziologie chirurgie MeSH
- perineum anatomie a histologie fyziologie chirurgie MeSH
- postmenopauza fyziologie MeSH
- prolaps pánevních orgánů patofyziologie MeSH
- pružnost fyziologie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- tuková tkáň anatomie a histologie MeSH
- vagina MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
PURPOSE OF THE STUDY Periprosthetic distal femoral fractures (PDFF) constitute an unpleasant complication in patients with a total knee replacement (TKR). The incidence reported in literature is 0.3-2.5 %. The number of periprosthetic knee fractures has been increasing due to the ageing of population, a growing number of implants, a longer life expectancy of patients, a more intensive physical activity of patients, and osteoporosis. Most of these fractures are treated surgically, non-surgical treatment is reserved solely for patients unable to undergo a surgery for general health conditions. MATERIAL AND METHODS Our retrospective study evaluated the group of patients with PDFF who were treated at out department in the period 2007- 2016 and 2,975 primary TKR were performed. The total number of patients with PDFF was 56. The mean age of patients with PDFF was 77 years (56-94 years) and at the time of fracture the mean age was 71 years in men and 78 years in women. The average time from the TKR to periprosthetic fracture was 8.2 years (0-20 years). The fractures were assessed using the Su classification modified by Krbec. RESULTS A primary TKR was performed in 46 cases for gonarthrosis, in 6 cases for rheumatoid arthritis and in 4 cases for secondary, post-traumatic gonarthrosis. The average incidence of periprosthetic distal femoral fractures was 5-6 cases per year. Women represented 86 %, men 14 %. Su Type I fracture was diagnosed in 25 % of cases, Su Type II fractures in 71 %, and Su Type III fractures 4 %. 52 patients with PDFF were treated surgically, in 4 cases conservative treatment was opted for. The average treatment time of PDFF to healing by callus formation was 6.6 months (3-12 months). Mortality during the first 3 months after osteosynthesis of PDFF was 9 %. A failure of osteosynthesis of PDFF was reported in 4 cases. DISCUSSION Multiple classification systems were developed to assess these fractures. The most appropriate we consider the classification of Su et al. classifying the PDFF into 3 groups, namely based on the height of the fracture line relative to the femoral component. Osteosynthesis by retrograde femoral nail is indicated for periprosthetic fractures, with sufficient bone mass in distal femur, which allows stable distal fixation. The new generation of anatomically shaped angular stable implants gives us yet another option for osteosynthesis of PDFF. Many studies point at the advantages of these implants in osteoporotic bone as against the conventional plates. CONCLUSIONS The number of PDFF has been increasing. The main methods of internal osteosynthesis continue to be the angular stable plates and the retrograde femoral nail. Preoperative planning is important to determine the type and dimensions of the existing femoral component and to distinguish whether or not it has come loose. The choice of the implant may depend on the bone mass available for distal fixation. The retrograde femoral nail is usually the most suitable method of treatment for proximal PDFF (Su Type I). The angular stable plates can be used for PDFF originating at the femoral component (Su Type II and Type III). Very distal fractures classified as Su Type III with a loose femoral component require a revision surgery with a TKR with stems. The surgeon should be prepared for a revision surgery if the intraoperative finding is more complicated than anticipated based on the preoperative radiograph. Key words:total knee arthroplasty, periprosthetic fracture, osteosynthesis.
- MeSH
- fraktury femuru etiologie chirurgie terapie MeSH
- kostní destičky MeSH
- lidé středního věku MeSH
- lidé MeSH
- osteoporotické fraktury etiologie chirurgie terapie MeSH
- periprotetické fraktury etiologie chirurgie terapie MeSH
- reoperace MeSH
- retrospektivní studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- totální endoprotéza kolene škodlivé účinky MeSH
- vnitřní fixace fraktury škodlivé účinky metody MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
OBJECTIVE: The aim of this study was to evaluate whether a previously identified modification of Viennese method of perineal protection remains most effective for reduction of perineal tension in cases with substantially smaller or larger fetal heads. METHODS: A previously designed finite element model was used to compare perineal tension of different modifications of the Viennese method of perineal protection to "hands-off" technique for three different sizes of the fetal head. Quantity and extent of tension throughout the perineal body during vaginal delivery at the time when the suboccipito-bregmatic circumference passes between the fourchette and the lower margin of the pubis was determined. RESULTS: The order of effectiveness of different modifications of manual perineal protection was similar for all three sizes of fetal head. The reduction of perineal tension was most significant in delivery simulations with larger heads. The final position of fingers 2cm anteriorly from the fourchette (y = +2) consistently remains most effective in reducing the tension. The extent of finger movement along the anterior-posterior (y-axis) contributes to the effectiveness of manual perineal protection. CONCLUSION: Appropriately performed Viennese manual perineal protection seems to reduce the perineal tension regardless of the fetal head size, and thus the method seems to be applicable to reduce risk of perineal trauma for all parturients.
- MeSH
- analýza metodou konečných prvků MeSH
- hlava anatomie a histologie MeSH
- komplikace porodu prevence a kontrola MeSH
- lidé MeSH
- perineum zranění MeSH
- plod anatomie a histologie MeSH
- těhotenství MeSH
- vedení porodu škodlivé účinky metody MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
OBJECTIVE: To investigate anal incontinence following mediolateral or lateral episiotomy during a first vaginal delivery. METHODS: The present prospective follow-up study enrolled primiparous patients who underwent vaginal delivery including mediolateral or lateral episiotomy between April 1, 2010 and March 31, 2012. Participants completed interviews before delivery, and were given anal-incontinence questionnaires to be returned for analysis at 3 months and 6 months postpartum. Anal incontinence was defined as a St Mark's incontinence score above four and individual anal-incontinence components were analyzed separately; results were compared between the two episiotomy techniques. RESULTS: Questionnaires were returned by 300 and 366 patients who underwent mediolateral and lateral episiotomies, respectively; baseline characteristics were similar. Anal incontinence at 3 months and 6 months was recorded among 21 (7.0%) and 9 (3.0%) patients who underwent mediolateral and 27 (7.4%) and 20 (5.5%) who underwent lateral episiotomy, respectively. The study was underpowered to confirm equivalence between the groups; however, no statistically significant differences were observed in the rates of anal incontinence, flatus, solid or liquid incontinence, and de novo incontinence. Fecal urgency (P=0.017) and de novo fecal urgency (P=0.008) were more prevalent among patients who underwent lateral episiotomies at 6 months. CONCLUSION: Anal incontinence was comparable between primiparous patients who underwent mediolateral or lateral episiotomy. The association between lateral episiotomy and fecal urgency merits further scientific interest.
- MeSH
- dospělí MeSH
- epiziotomie škodlivé účinky MeSH
- fekální inkontinence epidemiologie etiologie MeSH
- komplikace porodu epidemiologie MeSH
- lidé MeSH
- mladý dospělý MeSH
- následné studie MeSH
- parita MeSH
- perineum chirurgie MeSH
- poporodní období MeSH
- prospektivní studie MeSH
- průzkumy a dotazníky MeSH
- těhotenství MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladý dospělý MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
1st edition 541 stran : ilustrace (převážně barevné), portréty, tabulky ; 24 cm
- Konspekt
- Ortopedie. Chirurgie. Oftalmologie
- NLK Obory
- chirurgie
- experimentální medicína
- NLK Publikační typ
- kolektivní monografie
OBJECTIVES: Comparison of the effects of two episiotomy types on sexual activity, dyspareunia and overall satisfaction after childbirth. STUDY DESIGN: A prospective follow-up study of a randomized comparative trial evaluating peripartum outcome of a vaginal delivery after mediolateral (MLE) or lateral (LE) episiotomy. MAIN OUTCOME MEASURES: The participants completed questionnaires regarding sexual activity, dyspareunia, perineal pain, aesthetic appearance and overall satisfaction 3 (3M) and 6 months (6M) postpartum. RESULTS: A total of 648 women were available for the analyses (306 MLE, 342 LE). The groups showed no difference regarding resumption and regularity of sex, timing of resumption, frequency and intensity of dyspareunia, perineal pain, aesthetic appearance or overall satisfaction 3M or 6M postpartum. 98.0% of women after MLE and 97.7% after LE resumed sexual intercourse within 6M after delivery (p = 0.74). In the same period 15.6% of women after MLE and 16.1% after LE suffered from considerable dyspareunia (p = 0.86). CONCLUSIONS: Quality of sexual life and perception of perineal pain after MLE is equivalent to LE.
- MeSH
- bolest epidemiologie etiologie MeSH
- dospělí MeSH
- dyspareunie epidemiologie etiologie MeSH
- epiziotomie metody MeSH
- koitus * MeSH
- kvalita života MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- následné studie MeSH
- poporodní období * MeSH
- porod MeSH
- prevalence MeSH
- prospektivní studie MeSH
- průzkumy a dotazníky MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- randomizované kontrolované studie MeSH
- srovnávací studie MeSH
PURPOSE OF THE STUDY: A comparison of radiological and clinical results between dorsal pelvic segment stabilization with a transiliac internal fixator (TIFI) and that with two iliosacral screws (IS). MATERIAL AND METHODS: In this prospective study, both the TIFI and the IS group had 32 patients. The majority of injuries were assessed as type C1.3 because only patients with a high-energy mechanism of injury were included. Radiological results were evaluated according to the Matta scoring system and clinical outcome using the Majeed score and the Pelvic Outcome Score. Categorical data were evaluated by the two-sided Fisher's exact test or Pearson's χ2 test and continuous data by Student's t-test. A test result with p<0.05 was considered statistically significant. RESULTS: In the TIFI group, the mean posterior displacement was 2.2 mm, in the IS group it was 1.9 mm (p=0.58542). The pelvic outcome scores in the TIFI group were: excellent, 28%; good, 12%; fair, 48.0%; and poor, 4 %; in the IS group they were: excellent, 11.1%; good, 22.2%; fair, 66.7%; and poor, 0.0% (p=0.51731). The Majeed scores were as follows: excellent, 56.0%; good, 16.0%; fair, 20.0%; poor 8.0 % for the TIFI group and excellent, 50.0%; good, 27.8%; fair, 11.1%; and poor, 11.1% for the IS group (p=0.70187). Within the total, average Majeed score was 80.64 points in TIFI, 80.67 in IS (p=0.99654). In a sub-analysis of unilateral transforaminal fractures (Pohlemann type II), the average score for TIFI was 82.8 points and only 53.5 points for IS; the differences were statistically significant (p=0.04517). No intraoperative complications were associated with TIFI and one injury to the superior gluteal artery (3.1%) and two iatrogenic neurological injuries with IS (6.3%; p=0.23810). In the TIFI group, the fixator was removed without complications. In the IS group, post-operative wound bleeding following screw removal occurred in three patients (20.0%; p=0.22414), complete extraction of screws and washers was successful only in seven patients (46.7%), washers were left in situ in six patients (40.0 %) and IS removal was not possible in two patients (13.3%). The difference in complications between the groups was highly significant (p=0.00220). DISCUSSION: The results of our study are in agreement with those of the relevant studies published recently as well as with the outcomes of transiliac plate fixation reported in the literature. TIFI implantation is preferred in transforaminal and central sacral fractures because, unlike iliosacral screws, it carries a low risk of excessive compression of the sacral foramina and iatrogenic neurological injury. There were no significant differences in clinical and radiological findings between TIFI and IS procedures. Only in unilateral transforaminal fracture the TIFI stabilization had better outcome, as shown by the Majeed score. The IS fixation was associated with a higher rate of complications not only in primary implantation, but also at implant removal. CONCLUSIONS: The TIFI technique is superior to the IS procedure in fixation of unilateral transforaminal fractures and provides a reasonable alternative to the existing types of minimally invasive fixation.
- MeSH
- fraktury kostí radiografie chirurgie MeSH
- interní fixátory * MeSH
- kostní šrouby * MeSH
- lidé MeSH
- miniinvazivní chirurgické výkony přístrojové vybavení metody MeSH
- os ilium chirurgie MeSH
- pánevní kosti zranění radiografie chirurgie MeSH
- prospektivní studie MeSH
- vnitřní fixace fraktury přístrojové vybavení metody MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- hodnotící studie MeSH
- srovnávací studie MeSH
