- Keywords
- systém RetCAD, systém Aireen, systém IDx-DR, kamera Apollo CRO-01,
- MeSH
- Diabetic Retinopathy * diagnostic imaging MeSH
- Diabetes Complications diagnosis prevention & control MeSH
- Humans MeSH
- Ophthalmoscopes MeSH
- Image Processing, Computer-Assisted instrumentation MeSH
- Diagnostic Screening Programs * MeSH
- Software classification MeSH
- Patient Care Team MeSH
- Artificial Intelligence MeSH
- Education MeSH
- Check Tag
- Humans MeSH
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- MeSH
- Diagnostic Techniques, Ophthalmological * MeSH
- Humans MeSH
- Tomography, Optical Coherence methods MeSH
- Optometry methods MeSH
- Multiple Sclerosis * complications MeSH
- Slit Lamp MeSH
- Color Perception Tests methods MeSH
- Visual Field Tests methods MeSH
- Optic Neuritis * diagnosis etiology MeSH
- Evoked Potentials, Visual MeSH
- Check Tag
- Humans MeSH
Multispectral imaging is used in various applications including astronomy, industry and agriculture. In retinal imaging, the single-shot multispectral image stack is typically acquired and analyzed. This multispectral analysis can provide information on various structural or metabolic properties. This paper describes the multispectral improvement of a video-ophthalmoscope, which can acquire retinal video sequences of the optic nerve head and peripapillary area using various spectral light illumination. The description of the multispectral video imaging is provided and several applications are described. These applications include multispectral retinal photoplethysmography, visualization of spontaneous vein pulsation and multispectral RGB image generation.
- MeSH
- Diabetes Mellitus prevention & control MeSH
- Diabetic Retinopathy * prevention & control MeSH
- Diagnostic Services MeSH
- Fundus Oculi MeSH
- Diabetes Complications MeSH
- Humans MeSH
- Interdisciplinary Communication MeSH
- Retinal Diseases prevention & control MeSH
- Ophthalmoscopes MeSH
- Vision Screening methods MeSH
- Diagnostic Screening Programs * MeSH
- Slit Lamp MeSH
- Telemedicine MeSH
- Check Tag
- Humans MeSH
- Keywords
- analýza vrstvy nervových vláken sítnice,
- MeSH
- Child MeSH
- Adult MeSH
- Optic Disk Drusen * diagnosis complications MeSH
- Photography MeSH
- Middle Aged MeSH
- Humans MeSH
- Nerve Fibers pathology MeSH
- Optic Nerve pathology MeSH
- Intraocular Pressure MeSH
- Eye ultrasonography MeSH
- Tomography, Optical Coherence MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Slit Lamp MeSH
- Severity of Illness Index * MeSH
- Visual Acuity MeSH
- Visual Fields MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
BACKGROUND: Analysis of fast temporal changes on retinas has become an important part of diagnostic video-ophthalmology. It enables investigation of the hemodynamic processes in retinal tissue, e.g. blood-vessel diameter changes as a result of blood-pressure variation, spontaneous venous pulsation influenced by intracranial-intraocular pressure difference, blood-volume changes as a result of changes in light reflection from retinal tissue, and blood flow using laser speckle contrast imaging. For such applications, image registration of the recorded sequence must be performed. METHODS: Here we use a new non-mydriatic video-ophthalmoscope for simple and fast acquisition of low SNR retinal sequences. We introduce a novel, two-step approach for fast image registration. The phase correlation in the first stage removes large eye movements. Lucas-Kanade tracking in the second stage removes small eye movements. We propose robust adaptive selection of the tracking points, which is the most important part of tracking-based approaches. We also describe a method for quantitative evaluation of the registration results, based on vascular tree intensity profiles. RESULTS: The achieved registration error evaluated on 23 sequences (5840 frames) is 0.78 ± 0.67 pixels inside the optic disc and 1.39 ± 0.63 pixels outside the optic disc. We compared the results with the commonly used approaches based on Lucas-Kanade tracking and scale-invariant feature transform, which achieved worse results. CONCLUSION: The proposed method can efficiently correct particular frames of retinal sequences for shift and rotation. The registration results for each frame (shift in X and Y direction and eye rotation) can also be used for eye-movement evaluation during single-spot fixation tasks.
Cíl: Cílem práce bylo analyzovat soubor pacientů s drúzami papily zrakového nervu se zaměřením na možné komplikace tohoto onemocnění. Metodika: V našem souboru jsme vyšetřili 46 očí 23 pacientů s podezřením na drúzy papily zrakového nervu v období od 05/2013 do 01/2014. U všech dospělých pacientů jsme provedli biomikroskopické vyšetření předního i zadního segmentu, zjistili vizus, změřili nitrooční tlak, provedli vyšetření zorného pole, sonografické vyšetření bulbu (A i B scan), analýzu vrstvy nervových vláken sítnice na optické koherentní tomografii a barevnou a red-free fotografii. Drúzy jsme rozlišili dle biomikroskopického nálezu na drúzy neviditelné (zjistitelné jen sonograficky) – stupeň 0, viditelné drobné drúzy – stupeň I, na mnohočetné drúzy (konglomeráty) – stupeň II. Výsledky: Z 23 pacientů s drúzami papily zrakového nervu bylo 14 žen a 9 mužů. Věk pacientů se pohyboval v rozmezí od 8 do 82 let, s průměrným věkem 44,4 let. V souboru byly tři děti (8, 11 a 13 let). Dvaadvacet pacientů mělo drúzy papily zrakového nervu bilaterálně, jedna pacientka měla drúzy jen na pravém oku. Stupeň drúz byl hodnocen od 0 až do II u všech 45 očí v závislosti na množství drúz, uložení a viditelnosti drúz. Do stupně 0 byly zařazeny drúzy papily zrakového nervu u 11 pacientů, 10 pacientů mělo drúzy papily zrakového nervu oboustranně, jedna pacientka jednostranně. Z těchto 11 pacientů tři byly děti. Devět pacientů mělo drúzy papily zrakového nervu stupně I bilaterálně a tři pacienti se stupněm II bilaterálně. U drúz stupně 0 nebyl zaznamenán defekt zorného pole. U drúz stupně I byl zaznamenán defekt zorného pole u dvou pacientů z devíti (u čtyř očí) a u drúz stupně II byl defekt u dvou ze tří pacientů (tří očí). Srovnání tloušťky vrstvy nervových vláken - RNFL na optické koherentní tomografii bylo mezi každou ze tří skupin drúz stupně 0 až II. Vyšší stupně měly postupně tenčí RNFL. Ve srovnání s drúzami stupně 0 drúzy stupně I a II ukázaly významné ztenčení RNFL superiorně. U tří pacientů (u drúz stupně 0 a I) jsme pozorovali jiné komplikace drúzových papil. U pacientky s drúzami stupně I byla porucha vizu pro parciální hemoftalmus na levém oku a dále parapapilární hemoragie. U pacienta s drúzami stupně 0 byla oboustranná porucha vizu dána cystoidním makulárním edémem bilaterálně na podkladě drúz. Pacient měl také hemoragie parapapilárně a parciální hemoftalmus na horším levém oku. U jedné pacientky s drúzami stupně 0 byly pozorovány tortuózní cévy. Závěr: Drúzy papily zrakového nervu se vyskytují u 0,3–1 % populace a jsou bilaterální přibližně u 75–91 % případů. Je důležité odlišit drúzy papily zrakového nervu od papiloedému. Drúzy papily zrakového nervu mohou způsobit vážné defekty zorného pole, úbytek vrstvy nervových vláken a mohou být doprovázeny cévními komplikacemi. Pacienti s drúzami papily zrakového nervu by měli pravidelně podstoupit oční kontroly se zaměřením na nitrooční tlak, zorné pole a analýzu vrstvy nervových vláken. U pacientů s poruchou zorného pole a hraničním nitroočním tlakem je doporučována antiglaukomová terapie.
The aim of the study was to analyze the group of patients with optic disc drusen focusing on possible complications of this disease. Material and methods: In our group of patients, we examined 46 eyes of 23 patients with the suspicion of optic disc drusen during the period from May 2013 until January 2014. In all adult patients, we examined the anterior and posterior segment of the eye biomicroscopically, established the visual acuity, measured the intraocular pressure, examined the visual field, performed the ultrasound examination of the eye (A and B-scan), analyzed the retinal nerve fiber layer (RNFL) by means of optic coherence tomography (OCT), and color and red-free photography. According to the biomicroscopical findings, the drusen were divided into invisible drusen (buried drusen) (verified by ultrasound only) – grade 0, visible delicate drusen – grade I, and multiple drusen (conglomerates) – grade II. Results: Out of 23 patients, 14 were women and 9 were men. The age of the patients ranged from 8 to 82 years, the mean age was 44.4 years. In the group, there were 3 children (8, 11, and 13 years). In twenty-two patients, the drusen were present bilaterally, and one female patient had drusen on the right eye only. The grade of the drusen was set from 0 to II in all 45 eyes according to their amount, location, and visibility. As grade 0 were evaluated drusen in 11 patients; out of them, 10 patients had drusen bilaterally, and one female patient unilaterally. Out of these 11 patients, three were children. Grade I optic disc drusen bilaterally had nine patients, and three patients had drusen grade II bilaterally. In grade 0 drusen, no defect of the visual field was noticed. In drusen grade I, it was noticed the defect of the visual field in two patients (four eyes) out of nine patients, and in grade II the defect was present in two out of three patients (three eyes). The evaluation of the RNFL, by means of OCT, was performed among all three groups according to their grade 0 – II. In higher grades, the thickness of the RNFL was lower. Comparing to drusen grade 0, the drusen grade I, and II presented serious thinning of the RNFL superiorly. In three patients (drusen grade 0 and I) other complications of the optic disc drusen were observed. In one female patient with drusen grade I, there was decrease of the visual acuity due to the partial intravitreal hemorrhage in her left eye and parapapillary located retinal hemorrhages. In one male patient with drusen grade 0 was bilateral decrease of the VA due to cystoid macular edema caused by drusen. This patient had also retinal hemorrhages located near the papilla and partial intravitreal hemorrhage in his worse left eye. In one female patient with the drusen grade 0, the tortuous veins were noticed. Conclusion: Drusen of the optic disc are present in 0.3 – 1.0 % of the population, and are bilateral in approximately 75 – 91 % of the cases. It is important to distinguish optic nerve disc drusen from the papiledema. Drusen of the optic nerve can cause severe defects of the visual field, decrease of the retinal nerve fiber layer, and may be accompanied by vessels complications. Patients with the optic disc drusen should regularly undergo ophthalmologic examinations focused on the intraocular pressure, visual field testing, and retinal fiber layer analysis. In patients with visual field defect and borderline values of intraocular pressure, the antiglaucomatic therapy is recommended.
- Keywords
- analýza vrstvy nervových vláken sítnice,
- MeSH
- Child MeSH
- Adult MeSH
- Optic Disk Drusen * diagnosis complications MeSH
- Photography MeSH
- Middle Aged MeSH
- Humans MeSH
- Nerve Fibers pathology MeSH
- Optic Nerve pathology MeSH
- Intraocular Pressure MeSH
- Eye ultrasonography MeSH
- Tomography, Optical Coherence MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Slit Lamp MeSH
- Severity of Illness Index * MeSH
- Visual Acuity MeSH
- Visual Fields MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
Ophthalmic diseases are common in rabbits and rodents. Fast and definitive diagnosis is imperative for successful treatment of ocular diseases. Ophthalmic examination in rabbits and rodents can be challenging. Oculoscopy offers great magnification for the examination of the ocular structures in such animals, including the evaluation of cornea, anterior eye chamber, limbus, iris, lens, and retina. To date, oculoscopy has been described only sporadically and/or under experimental conditions. This article describes the oculoscopy technique, normal and abnormal ocular findings, and the most common eye disorders diagnosed with the aid of endoscopy in rabbits and rodents.
- MeSH
- Rodentia anatomy & histology MeSH
- Rabbits anatomy & histology MeSH
- Rodent Diseases diagnosis MeSH
- Eye anatomy & histology MeSH
- Eye Diseases diagnosis veterinary MeSH
- Ophthalmoscopes veterinary MeSH
- Animals MeSH
- Check Tag
- Rabbits anatomy & histology MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- MeSH
- Larva parasitology MeSH
- Middle Aged MeSH
- Humans MeSH
- Myiasis * diagnosis etiology parasitology physiopathology therapy MeSH
- Slit Lamp MeSH
- Treatment Outcome MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Case Reports MeSH
- MeSH
- Biometry MeSH
- Diagnostic Techniques, Ophthalmological * classification instrumentation MeSH
- Iris * anatomy & histology MeSH
- Humans MeSH
- Eye MeSH
- Ophthalmoscopes classification MeSH
- Retina * anatomy & histology MeSH
- Slit Lamp MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
