Cerebral perfusion
Dotaz
Zobrazit nápovědu
Článek se zabývá postupem zpracování dat získaných komerční vyšetřovací EPI sekvencí NMR jednotky Siemens Symphony 1,5 T. Naměřená data byla převedena na osobní počítač a zpracována vlastním programem, který vytváří kalkulované obrazy podle různých parametrů.
The article describes processing of data from commercial EPI sequence MRI unit Siemens Symphony 1.5 T. The data were transferred to a personal computer and processed using self-designed software package, creating calculated images of various perfusion parameters.
Cerebrovascular diseases, ISSN 1015-9770
svazky ; 30 cm
XI, 152 s. : il., tab. ; 26 cm + 1 CD-ROM
Acta physiologica Scandinavica ; Vol. 154 Suppplement 625
44 s. : grafy ; 24 cm
... metabolism -- Models of blood flow and metabolism -- Global control of blood flow -- Local control of perfusion ... ... -- Externally-based measurements -- Internally-based measurements -- Global changes in cerebral blood ... ... flow and metabolism -- Local changes in cerebral blood flow and metabolism -- Conclusions ...
xxvi, 440 stran : ilustrace
Journal of cerebral blood flow and metabolism, ISSN 0271-678X vol. 23, suppl. 1, June 2003
762 s. : tab., grafy ; 28 cm
- MeSH
- cerebrovaskulární poruchy MeSH
- mozek metabolismus MeSH
- mozkový krevní oběh MeSH
- regionální krevní průtok MeSH
- Publikační typ
- abstrakty MeSH
- kongresy MeSH
- sborníky MeSH
- Konspekt
- Fyziologie člověka a srovnávací fyziologie
- NLK Obory
- neurovědy
- kardiologie
- angiologie
- vnitřní lékařství
Cerebral perfusion pressure (CPP) is the net pressure gradient that drives oxygen delivery to cerebral tissue. It is the difference between the mean arterial pressure (MAP) and the intracranial pressure (ICP). As CPP is a calculated value, MAP and ICP must be measured simultaneously. In research models, anesthetized and acute monitoring is incapable of providing a realistic picture of the relationship between ICP and MAP under physiological and/or pathophysiological conditions. For long-term monitoring of both pressures, the principle of telemetry can be used. The aim of this study was to map changes in CPP and spontaneous behavior using continuous pressure monitoring and video recording for 7 days under physiological conditions (group C - 8 intact rats) and under altered brain microenvironment induced by brain edema (group WI - 8 rats after water intoxication) and neuroprotection with methylprednisolone - MP (group WI+MP - 8 rats with MP 100 mg/kg b.w. applicated intraperitoneally during WI). The mean CPP values in all three groups were in the range of 40-60 mm Hg. For each group of rats, the percentage of time that the rats spent during the 7 days in movement pattern A (standard movement stereotype) or B (atypical movement) was defined. Even at very low CPP values, the standard movement stereotype (A) clearly dominated over the atypical movement (B) in all rats. There was no significant difference between control and experimental groups. Chronic CPP values with correlated behavioral type may possibly answer the question of whether there is a specific, universal, optimal CPP at all.
Journal of cerebral blood flow and metabolism, ISSN 0271-678X Supplement Vol. 17. 1
S806 s. : il. ; 30 cm
- MeSH
- molekulární biologie MeSH
- mozkový krevní oběh účinky léků fyziologie MeSH
- nemoci mozku MeSH
- terapie MeSH
- Publikační typ
- abstrakty MeSH
- kongresy MeSH
- Konspekt
- Lékařské vědy. Lékařství
- NLK Obory
- neurologie
- kardiologie
- fyziologie
- angiologie
