... Lindberg. 1 -- Editorial Health Informatics and the Internet. J.H. van Bemmel and A.T. ... ... Health informatics education and research at the University of Athens. 95 PinciroliF. ... ... Networks: The ‘fabric of life’ for informatics applications. ... ... Yearbook of Medical Informatics 1998 -- VII -- Table of Contents -- 471 Haux R. ... ... Section 7: Health and medical informatics education. ...
ix, 534 stran : ilustrace, tabulky ; 28 cm
- MeSH
- Medical Records Systems, Computerized MeSH
- Internet MeSH
- Knowledge Management MeSH
- Decision Support Techniques MeSH
- Image Processing, Computer-Assisted MeSH
- Signal Processing, Computer-Assisted MeSH
- Health Services Administration MeSH
- Education, Medical MeSH
- Health Information Systems MeSH
- Publication type
- Collected Work MeSH
- Conspectus
- Lékařské vědy. Lékařství
- NML Fields
- lékařská informatika
- NML Publication type
- ročenky
Cíle: Cílem této práce je navrhnout vylepšenou metodu autentizace pro biomedicínu založenou na analýze behaviorálních biometrických metod používaných v soucasnosti. Metody: Práce poskytuje strucnou definici identifikace, autentizace a biometrických charakteristik. Hlavní cást práce se zabývá dynamikou stisku pocítacových kláves, jejími výhodami, nevýhodami a aplikacemi v biomedicíne. Dynamika stisku pocítacových kláves je následne navržena jako zajímavá behaviorální charakteristika pro použití v pocítacové bezpecnosti, která doposud není široce používaná. Výsledky: Výsledkem práce bude nový soubor metod, který umožní optimální multifaktorovou autentizaci z hlediska pohodlí, nákladu a spolehlivosti. Záver: Cílem tohoto príspevku je soustredit se na dostupné informace o dynamice stisku pocítacových kláves.
Objectives: The goal of this work is to suggest an improved authentication method for biomedicine based on analysis of currently used behavioural biometric methods. Methods: A brief definition of identification, authentication and biometric characteristics is provided. The main part of the work focuses on keystroke dynamics, its advantages, disadvantages and applications in biomedicine. Keystroke dynamics is then proposed as an interesting behavioural biometric characteristic for use in computer security not being widely used so far. Results: The result of the work will be a new set of methods, which allows optimal multi-factor authentication method regarding its comfort, cost and reliability. Conclusions: The purpose of this paper is to focus on the available information about keystroke dynamics.
In the "producer-scrounger" model, a producer discovers a resource and is in turn discovered by a second individual, the scrounger, who attempts to steal it. This resource can be food or a territory, and in some situations, potentially divisible. In a previous paper we considered a producer and scrounger competing for an indivisible resource, where each individual could choose the level of energy that they would invest in the contest. The higher the investment, the higher the probability of success, but also the higher the costs incurred in the contest. In that paper decisions were sequential with the scrounger choosing their strategy before the producer. In this paper we consider a version of the game where decisions are made simultaneously. For the same cost functions as before, we analyse this case in detail, and then make comparisons between the two cases. Finally we discuss some real examples with potentially variable and asymmetric energetic investments, including intraspecific contests amongst spiders and amongst parasitoid wasps. In the case of the spiders, detailed estimates of energetic expenditure are available which demonstrate the asymmetric values assumed in our models. For the wasps the value of the resource can affect the probabilities of success of the defender and attacker, and differential energetic investment can be inferred. In general for real populations energy usage varies markedly depending upon crucial parameters extrinsic to the individual such as resource value and intrinsic ones such as age, and is thus an important factor to consider when modelling.
- MeSH
- Aggression * MeSH
- Models, Biological * MeSH
- Behavior, Animal * MeSH
- Host-Parasite Interactions physiology MeSH
- Competitive Behavior MeSH
- Mathematical Concepts MeSH
- Spiders parasitology physiology MeSH
- Decision Making MeSH
- Wasps pathogenicity physiology MeSH
- Game Theory * MeSH
- Computational Biology MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
... Medical Informatics as an Integrative Task in Health Care -- Engelbrecht R. ... ... Donnelly W.A. 102 - CONSUMER BEHAVIOUR -- Private Health Consumption in Greece Today. ... ... Investigation of Systems of Prevention from Informatics Point of View. Simon P. ... ... Kankaanpää J. 602 - EDUCATION IN MEDICAL INFORMATICS -- Development of a Master’s Course on Health Informatics ... ... The Enduring Qualities of Medical Informatics. Kay S. ...
1589 s. : il. ; 24 cm
- MeSH
- Health Care Economics and Organizations MeSH
- Medical Informatics MeSH
- Health Care Surveys MeSH
- Health Care Reform MeSH
- Quality Assurance, Health Care MeSH
- Publication type
- Congress MeSH
- Conspectus
- Veřejné zdraví a hygiena
- NML Fields
- veřejné zdravotnictví
Sdělení popisuje dynamické chování vázaných řiditelných pseudooscilátorů představovaných srdcem a plícemi při zátěžovém testu. Na základě fyzikálních poznatků a poznatků z teorie systémů můžeme chápat tento kardiorespirační systém jako systém vázaných řiditelných biologických pseudooscilátorů. Stručně bude pojednáno o biologické struktuře a řízení tohoto systému. Budou popsány dva typy ergometrických zátěžových testů I a II, kterými byly získány průběhy charakteristických veličin definovaného systému vázaných pseudooscilátorů. Průběhy těchto veličin jsou podrobně specifikovány velikostí maxim a dobou zpoždění reakce systému na zátěž. Je řešena i predikce vývoje veličin metodou nejmenších čtverců. Z dosažených výsledků je provedena detekce vazby mezi definovanými pseudooscilátory srdce – plíce. Detekce vazby je založena na frekvenční, fázové, intervalové synchronizaci a na korelační analýze. Z uvedených analýz se potvrdila obecná známost, že vazba existuje a charakteristické veličiny se synchronizují, což odpovídá skutečnosti. Na závěr jsou presentovány vnější parametry ARX modelu popisující dynamické chování sledovaných veličin v závislosti na fyzické zátěži a je s nimi provedena řada simulací.
The paper describes dynamic behaviour of bound controllable pseudo-oscillators represented by the heart and the lungs during an exercise stress test. Based on physical knowledge and the knowledge of system theory, this cardiorespiratory system can be understood as a system of bound controllable biological pseudo-oscillators. Biological structure and control of this system will be briefly discussed. Two types of ergometric exercise stress tests I and II will be described, which were used to obtain time courses of characteristic quantities of the defined bound pseudo-oscillator system. Time courses of these quantities are specified in detail by their maxima and by the delay time taken by the system to respond to the stress. Prediction of the quantities development is also addressed using the least squares method. The results achieved were used to detect the bound between the defined heart-lung pseudo-oscillators. This detection was based on frequency, phase, interval synchronization, and on correlation analysis. The undertaken analyses confirmed the general well-known fact, i.e. that a bound does exist and characteristic quantities are synchronized, which is in accordance with reality. In conclusion, external parameters of the ARX model are presented, which describe dynamic behaviour of observed quantities in dependence on physical stress, and they are subjected to a number of simulations.
V rámci projektu podpory zdraví (PPZ) „Národního programu zdraví" byl vytvořen webový portál pro praktickou prevenci nemocí a podporu zdravého životního stylu. Článek popisuje funkční možnosti portálu a dále dosažený efekt, hodnocený po ročním provozu. Portál má 3 hlavní funkce: informační strom, kalkulátor rizik a objednávání na bezplatné klinické preventivní vyšetření. Kalkulátor rizik umožňuje bezprostřední vyhodnocení individuálních faktorů životního stylu, jako je výživa, konzumace alkoholu, pohybová aktivita a kuřáctví a rovněž některých klinických parametrů. Aplikovaná metodika hodnocení výživy a dalších faktorů životního styluje originální a je zde detailně popsána.V průběhu ročního hodnoceného období bylo zaznamenáno přes 29 tisíc přístupů na stránky. V základní anketě na otázku: „Poskytuje tento server informace, které považujete za důležité pro zdraví a dobrou kondici?" odpovědělo kladně celkem 97 % z 2002 respondentů. Celkem 1186 návštěvníků kompletně vyplnilo kalkulátor rizik. Jejich průměrný věk byl 34 roků (rozmezí 13-61), ženy tvořily 63 %. Všem registrovaným byl v odstupu 3 měsíců od registrace rozeslán e-mailem kontrolní dotazník k hodnocení efektu stránek. Návratnost byla 89 %, 100 % respondentů uvedlo změnu svých znalostí, 88 % změnu postojů a 75 % realizovanou změnu chování. Klinické preventivní vyšetření se pomocí objednání přes portál podařilo realizovat u 435 zájemců, a u 42 % z nich (167 osob) bylo uskutečněno opakované kontrolní vyšetření. U všech kontrolních vyšetření bylo detekováno určité zlepšení a žádné zhoršení. Popisované webové stránky jsou stále volně přístupné, především pro laické, případně i odborné využití při praktické prevenci neinfekčních nemocí.
A web site for disease prevention and health promotion was created within the framework of the "National Health Program", a health promotion project (HPP). The article describes the functional options of the site and its effect evaluated after one year of operation. The site has three main functions: an information tree, a risk calculator, and an option for making an appointment for a complimentary preventivě clinical checkup. The risk calculator enables direct evaluation of individual lifestyle risk factors, such as nutrition, alcohol consumption, physical activity, and smoking, together with some clinical parameters. The applied methodology of evaluation of nutrition and other lifestyle factors is originál and fully described in the article. Over the course of the one year evaluation period, more than 29 000 user entries were recorded. In a basic questionnaire, 97 % from 2002 respondents favourably answered the question: "Does this server provide information you consider important for your health and good condition?" In total, 1 186 visitors completed the risk calculator. Their average age was 34 years (range 13-61), 63 % were female. Three months after registration, all registered users obtained a questionnaire for the web site evaluation. The response rate was 89 %, 100 % respondents claimed a change in their knowledge, 88 % a change of attitude, and 75 % a change of behaviour. A preventivě clinical check-up made via the site was provided to 435 individuals, 42 % (167 individuals) underwent a repeat check-up. In all repeated check-ups a certain improvement, but no deterioration, was recorded. The web pages described are still freely accessible, mainly for non-professional, but also professional usage for the practical prevention of non-infectious diseases.
Feature selection is a significant part of many machine learning applications dealing with small-sample and high-dimensional data. Choosing the most important features is an essential step for knowledge discovery in many areas of biomedical informatics. The increased popularity of feature selection methods and their frequent utilisation raise challenging new questions about the interpretability and stability of feature selection techniques. In this study, we compared the behaviour of ten state-of-the-art filter methods for feature selection in terms of their stability, similarity, and influence on prediction performance. All of the experiments were conducted on eight two-class datasets from biomedical areas. While entropy-based feature selection appears to be the most stable, the feature selection techniques yielding the highest prediction performance are minimum redundance maximum relevance method and feature selection based on Bhattacharyya distance. In general, univariate feature selection techniques perform similarly to or even better than more complex multivariate feature selection techniques with high-dimensional datasets. However, with more complex and smaller datasets multivariate methods slightly outperform univariate techniques.
- MeSH
- Algorithms MeSH
- Databases, Factual MeSH
- Humans MeSH
- Multivariate Analysis MeSH
- Parkinson Disease diagnosis MeSH
- Oligonucleotide Array Sequence Analysis methods MeSH
- Software MeSH
- Models, Statistical MeSH
- Computational Biology methods MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Comparative Study MeSH
Development in the area of sensor technologies and subsequently applications within the Internet of Things allows the implementation of systems for continuous monitoring of human's vital parameters and daily activities. This development is welcomed since the population aged 65 and over is constantly increasing. Moreover, the number of seniors living alone is also increasing. The monitoring systems can contribute to the safety and security of elderly people and allow them to stay at home where they are used to live as long as possible. Application of various sensor types raises questions on the most suitable sensor data representation, not losing useful information, and also on the design of detection and evaluation algorithms. In the paper, we briefly present several existing approaches and explain why we decided to use the basic ideas coming from the area of behaviour informatics.
- MeSH
- Algorithms * MeSH
- Housing MeSH
- Electrocardiography * MeSH
- Humans MeSH
- Monitoring, Physiologic * MeSH
- Aged MeSH
- Arrhythmias, Cardiac MeSH
- Check Tag
- Humans MeSH
- Aged MeSH
- Publication type
- Journal Article MeSH
The AlphaFold2 prediction algorithm opened up the possibility of exploring proteins' structural space at an unprecedented scale. Currently, >200 million protein structures predicted by this approach are deposited in AlphaFoldDB, covering entire proteomes of multiple organisms, including humans. Predicted structures are, however, stored without detailed functional annotations describing their chemical behaviour. Partial atomic charges, which map electron distribution over a molecule and provide a clue to its chemical reactivity, are an important example of such data. We introduce the web application αCharges: a tool for the quick calculation of partial atomic charges for protein structures from AlphaFoldDB. The charges are calculated by the recent empirical method SQE+qp, parameterised for this class of molecules using robust quantum mechanics charges (B3LYP/6-31G*/NPA) on PROPKA3 protonated structures. The computed partial atomic charges can be downloaded in common data formats or visualised via the powerful Mol* viewer. The αCharges application is freely available at https://alphacharges.ncbr.muni.cz with no login requirement.
- MeSH
- Algorithms MeSH
- Protein Conformation MeSH
- Humans MeSH
- Proteins * chemistry MeSH
- Proteome MeSH
- Software * MeSH
- Computational Biology * instrumentation methods MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
Several constitutive models have been proposed for the description of mechanical behaviour of soft tissues containing collagen fibres. Some of the commonly used approaches accounting for the dispersion of fibre orientations are based on the summation of (mechanical) contributions of differently oriented fibre families. This leads to the need of numerical integration on the sphere surface, and the related numerical consumption is the main disadvantage of this category of constitutive models. The paper is focused on the comparison of various numerical integration methods applied to a specific constitutive model applicable for arterial walls. Robustness and efficiency of several integration rules were tested with respect to application in finite element (FE) codes. Among all the analysed numerical integration rules, the best results were reached by Lebedev quadrature; the related parameters for the specific constitutive model are presented in the paper. The results were implemented into the commercial FE code ANSYS via user subroutines, and their applicability was demonstrated by an example of FE simulation with non-homogenous stress field.
