1st ed. 73 s.
- MeSH
- Multivariate Analysis MeSH
- Reference Books MeSH
- Regression Analysis MeSH
- Students MeSH
- Publication type
- Handbook MeSH
- Conspectus
- Statistika
- NML Fields
- statistika, zdravotnická statistika
Statistics for Biology and Health -- Philip Hougaard -- Analysis of Multivariate Survival Data -- Survival This book extends the field by allowing for multivariate times. Four different approaches to the analysis of such data are presented. It can be used as a textbook for a graduate course in multivariate survival data. It is written from an applied point of view and covers all the essential aspects of applying multivariate
Statistics for biology and health
1st ed. xvii, 542 s.
- Conspectus
- Statistika
- NML Fields
- statistika, zdravotnická statistika
- management, organizace a řízení zdravotnictví
- MeSH
- Adrenergic beta-Antagonists pharmacology therapeutic use MeSH
- Adult MeSH
- Electrocardiography methods MeSH
- Tachycardia, Ventricular diagnosis pathology MeSH
- Humans MeSH
- Predictive Value of Tests MeSH
- Regression Analysis MeSH
- Long QT Syndrome diagnosis pathology MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Geographicals
- China MeSH
BACKGROUND: Left atrial (LA) enlargement is a predictor of worse outcome after catheter ablation for atrial fibrillation (AF). Widely used two-dimensional (2D)-echocardiography is inaccurate and underestimates real LA volume (LAV). We hypothesized that baseline clinical characteristics of patients can be used to adjust 2D-ECHO indices of LAV in order to minimize this disagreement. METHODS: The study enrolled 535 patients (59 ± 9 years; 67% males; 43% paroxysmal AF) who underwent catheter ablation for AF in three specialized centers. We investigated multivariately the relationship between 2D-echocardiographic indices of LA size, specifically LA diameter in M-mode in the parasternal long-axis view (LAD), LAV assessed by the prolate-ellipsoid method (LAVEllipsoid), LAV by the planimetric method (LAVPlanimetry), and LAV derived from 3D-electroanatomic mapping (LAVCARTO). RESULTS: Cubed LAD of 106 ± 45 ml, LAVEllipsoid of 72 ± 24 ml and LAVPlanimetry of 88 ± 30 ml correlated only modestly (r = 0.60, 0.69, and 0.53, respectively) with LAVCARTO of 137 ± 46 ml, which was significantly underestimated with a bias (±1.96 standard deviation) of -31 (-111; +49) ml, -64 (-132; +2) ml, and -49 (-125; +27) ml, respectively; p < 0.0001 for their mutual difference. LA enlargement itself, age, gender, type of AF, and the presence of structural heart disease were independent confounders of measurement error of 2D-echocardiographic LAV. CONCLUSION: Accuracy and precision of all 2D-echocardiographic LAV indices are poor. Their agreement with true LAV can be significantly improved by multivariate adjustment to clinical characteristics of patients.
- MeSH
- Echocardiography * MeSH
- Atrial Fibrillation ultrasonography MeSH
- Middle Aged MeSH
- Humans MeSH
- Multivariate Analysis MeSH
- Regression Analysis MeSH
- ROC Curve MeSH
- Heart Atria pathology ultrasonography MeSH
- Organ Size MeSH
- Imaging, Three-Dimensional * MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
Wiley series in probability and statistics
1st ed. xix, 506 s.
- Conspectus
- Statistika
- NML Fields
- statistika, zdravotnická statistika
3rd ed. xviii, 798 s.
- Conspectus
- Přírodní vědy. Matematické vědy
- NML Fields
- přírodní vědy
