interfaces
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sv.
- MeSH
- biokompatibilní materiály MeSH
- chemické jevy * MeSH
- Publikační typ
- periodika MeSH
- Konspekt
- Fyzikální chemie
- NLK Obory
- biomedicínské inženýrství
326 s. : il.
- Konspekt
- Biochemie. Molekulární biologie. Biofyzika
- NLK Obory
- biochemie
- fyziologie
- vnitřní lékařství
- MeSH
- fyzikální chemie MeSH
- povrchové vlastnosti MeSH
- testování materiálů MeSH
- Publikační typ
- periodika MeSH
- Konspekt
- Chemie. Mineralogické vědy
- NLK Obory
- chemie, klinická chemie
BACKGROUND: Brain sensing devices are approved today for Parkinson's, essential tremor, and epilepsy therapies. Clinical decisions for implants are often influenced by the premise that patients will benefit from using sensing technology. However, artifacts, such as ECG contamination, can render such treatments unreliable. Therefore, clinicians need to understand how surgical decisions may affect artifact probability. OBJECTIVES: Investigate neural signal contamination with ECG activity in sensing enabled neurostimulation systems, and in particular clinical choices such as implant location that impact signal fidelity. METHODS: Electric field modeling and empirical signals from 85 patients were used to investigate the relationship between implant location and ECG contamination. RESULTS: The impact on neural recordings depends on the difference between ECG signal and noise floor of the electrophysiological recording. Empirically, we demonstrate that severe ECG contamination was more than 3.2x higher in left-sided subclavicular implants (48.3%), when compared to right-sided implants (15.3%). Cranial implants did not show ECG contamination. CONCLUSIONS: Given the relative frequency of corrupted neural signals, we conclude that implant location will impact the ability of brain sensing devices to be used for "closed-loop" algorithms. Clinical adjustments such as implant location can significantly affect signal integrity and need consideration.
- MeSH
- algoritmy MeSH
- artefakty MeSH
- elektrokardiografie MeSH
- esenciální tremor * MeSH
- lidé MeSH
- rozhraní mozek-počítač * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
398 s. : il. ; 24 cm
- MeSH
- biokompatibilní materiály MeSH
- protézy a implantáty MeSH
- zubní implantáty MeSH
- Publikační typ
- kongresy MeSH
- Konspekt
- Biochemie. Molekulární biologie. Biofyzika
- NLK Obory
- fyzika, biofyzika
xxvi, 499 s : il ; 24 cm
Acta radiologica, ISSN 0365-5954 suppl. 332, 1973
64 s. : grafy ; 26 cm
[1st ed.] XIII, 499 s. : obr., tab., grafy ; 24 cm
The surfaces of aqueous solutions are traditionally viewed as devoid of inorganic ions. Molecular simulations and surface-selective spectroscopic techniques show, however, that large polarizable anions and hydronium cations can be found (and even enhanced) at the surface and are involved in chemistry at the air/water interface. Here, we review recent studies of ions at the air/water interface and compare from this perspective water with other polar solvents. For water, we focus in particular on the surface behavior of its ionic product (i.e., hydronium and hydroxide ions). We also investigate the feasibility of dielectric models for the description of the protein/water interface, in analogy to the air/water interface. Little correlation is found between these two interfaces in terms of ion segregation. Therefore, we suggest a local model of pairing of ions from the solution with charged and polar groups at the protein surface. We also describe corresponding results of experimental studies on aqueous model systems.
sv.
- MeSH
- fyzikální chemie MeSH
- nanostruktury MeSH
- Publikační typ
- periodika MeSH
- Konspekt
- Chemie. Mineralogické vědy
- NLK Obory
- chemie, klinická chemie
