coumarin OR C030123 Dotaz Zobrazit nápovědu
Journal of cancer research and clinical oncology ; Supplement Vol. 120. 1
[1st ed.] S42 s. : obr., tab., grafy ; 28 cm
- MeSH
- karcinom z renálních buněk farmakoterapie MeSH
- kumariny farmakologie MeSH
- melanom farmakoterapie MeSH
- nádory prostaty farmakoterapie MeSH
- společnosti lékařské MeSH
- Publikační typ
- kongresy MeSH
- sborníky MeSH
- Konspekt
- Lékařské vědy. Lékařství
- NLK Obory
- onkologie
- farmacie a farmakologie
- MeSH
- antikoagulancia škodlivé účinky toxicita MeSH
- kožní nemoci etiologie terapie MeSH
- kumariny škodlivé účinky toxicita MeSH
- lidé středního věku MeSH
- lidé MeSH
- nekróza etiologie terapie MeSH
- tromboflebitida farmakoterapie komplikace MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
- MeSH
- antikoagulancia škodlivé účinky MeSH
- fibrinolýza MeSH
- kožní nemoci etiologie MeSH
- kumariny škodlivé účinky MeSH
- lidé MeSH
- nekróza etiologie chirurgie MeSH
- senioři MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
We report on synthesis of new fluorescent probes suitable for site-specific incorporation into oligonucleotides. Coumarin derivatives were used as sensitive fluorescent labels and were attached to glycerol unit by two types of linkers as potential building blocks for oligonucleotide synthesis. Spectral characteristics of the functionalized coumarin building blocks were measured.
The objective of this study was to determine the coumarin content of ground cinnamon purchased from retail markets in the Czech Republic. No sample was labelled with information on the botanical source, but, in some cases, the countries of origin were specified. For comparison, a single cinnamon sample imported directly from a plantation in Sri Lanka that came from Cinnamomum verum was analyzed. Results from 60 ground cinnamon samples comprising twelve brands confirmed a high content of coumarin, with mean levels ranging from 2,650 to 7,017 mg · kg(-1). The high coumarin content confirmed that these cinnamon samples obtained from cassia cinnamon were in contrast to the sample from Sri Lanka, which was coumarin-free.
- MeSH
- analýza potravin metody MeSH
- kontaminace potravin analýza MeSH
- koření analýza MeSH
- kumariny analýza MeSH
- kůra rostlin chemie MeSH
- marketing MeSH
- skořicovník ceylonský chemie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
Coumarin (2H-1-benzopyran-2-one) is a phenolic compound derived from the shikimate pathway and synthesized by various medicinal and aromatic plants as parent molecule of a large group of secondary metabolites, namely coumarins. Its main utilization is as fixative in perfumes and flavour enhancer. Given its role as phytoalexin and phagodepression activity, herein we evaluated for the first time its efficacy against several insect species: the green peach aphid, Myzus persicae, the moth Spodoptera littoralis, the housefly, Musca domestica and the filariasis vector Culex quinquefasciatus. Two non-target species were also included in our toxicity evaluation experiments: the ladybug Harmonia axyridis and the earthworm Eisenia fetida. Results highlighted remarkable selectivity of coumarin, being highly toxic to M. persicae aphids (LC50(90) values of 1.3(1.9) mg L-1) and friendly to natural enemies of aphids as well as soil invertebrates.
- MeSH
- Culex účinky léků MeSH
- inhibiční koncentrace 50 MeSH
- insekticidy toxicita MeSH
- kumariny toxicita MeSH
- larva účinky léků MeSH
- moucha domácí účinky léků MeSH
- mšice účinky léků MeSH
- můry účinky léků MeSH
- rostlinné extrakty chemie MeSH
- semena rostlinná chemie MeSH
- Spodoptera účinky léků MeSH
- testy toxicity MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
