OBJECTIVE: Radiographic assessment of sacroiliac joints (SIJs) according to the modified New York (mNY) criteria is key in the classification of axial spondyloarthritis but has moderate interreader agreement. We aimed to investigate the improvements of the reliability in scoring SIJ radiographs after applying an online real-time iterative calibration (RETIC) module, in addition to a slideshow and video alone. METHODS: Nineteen readers, randomized to 2 groups (A or B), completed 3 calibration steps: (1) review of manuscripts, (2) review of slideshow and video with group A completing RETIC, and (3) re-review of slideshow and video with group B completing RETIC. The RETIC module gave instant feedback on readers' gradings and continued until predefined reliability ([Formula: see text]) targets for mNY positivity/negativity were met. Each step was followed by scoring different batches of 25 radiographs (exercises I to III). Agreement ([Formula: see text]) with an expert radiologist was assessed for mNY positivity/negativity and individual lesions. Improvements by training strategies were tested by linear mixed models. RESULTS: In exercises I, II, and III, mNY [Formula: see text] were 0.61, 0.76, and 0.84, respectively, in group A; and 0.70, 0.68, and 0.86, respectively, in group B (ie, increasing, mainly after RETIC completion). Improvements were observed for grading both mNY positivity/negativity and individual pathologies, both in experienced and, particularly, inexperienced readers. Completion of the RETIC module in addition to the slideshow and video caused a significant [Formula: see text] increase of 0.17 (95% CI 0.07-0.27; P = 0.002) for mNY-positive and mNY-negative grading, whereas completion of the slideshow and video alone did not ([Formula: see text] = 0.00, 95% CI -0.10 to 0.10; P = 0.99). CONCLUSION: Agreement on scoring radiographs according to the mNY criteria significantly improved when adding an online RETIC module, but not by slideshow and video alone.
- MeSH
- axiální spondyloartritida * diagnostické zobrazování MeSH
- lidé MeSH
- odchylka pozorovatele * MeSH
- rentgendiagnostika * metody MeSH
- reprodukovatelnost výsledků MeSH
- sakroiliakální kloub * diagnostické zobrazování MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- randomizované kontrolované studie MeSH
BACKGROUND: The Spondyloarthritis Research Consortium of Canada (SPARCC) developers have created web-based calibration modules for the SPARCC MRI sacroiliac joint (SIJ) scoring methods. We aimed to test the impact of applying these e-modules on the feasibility and reliability of these methods. METHODS: The SPARCC-SIJ RETIC e-modules contain cases with baseline and follow-up scans and an online scoring interface. Visual real-time feedback regarding concordance/discordance of scoring with expert readers is provided by a colour-coding scheme. Reliability is assessed in real time by intraclass correlation coefficient (ICC), cases being scored until ICC targets are attained. Participating readers (n=17) from the EuroSpA Imaging project were randomised to one of two reader calibration strategies that each comprised three stages. Baseline and follow-up scans from 25 cases were scored after each stage was completed. Reliability was compared with a SPARCC developer, and the System Usability Scale (SUS) assessed feasibility. RESULTS: The reliability of readers for scoring bone marrow oedema was high after the first stage of calibration, and only minor improvement was noted following the use of the inflammation module. Greater enhancement of reader reliability was evident after the use of the structural module and was most consistently evident for the scoring of erosion (ICC status/change: stage 1 (0.42/0.20) to stage 3 (0.50/0.38)) and backfill (ICC status/change: stage 1 (0.51/0.19) to stage 3 (0.69/0.41)). The feasibility of both e-modules was evident by high SUS scores. CONCLUSION: The SPARCC-SIJ RETIC e-modules are feasible, effective knowledge transfer tools, and their use is recommended before using the SPARCC methods for clinical research and tria.
- MeSH
- lidé MeSH
- magnetická rezonanční tomografie metody MeSH
- reprodukovatelnost výsledků MeSH
- sakroiliakální kloub * diagnostické zobrazování patologie MeSH
- spondylartritida * diagnóza patologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- randomizované kontrolované studie MeSH
- Geografické názvy
- Kanada MeSH
BACKGROUND: Carotid endarterectomy is beneficial in symptomatic patients with ≥70% stenosis at the bifurcation of the internal carotid artery. The fact that the duplex ultrasound is widely used, inexpensive and non-invasive for examination of the carotid arteries underlines the importance of high accuracy of this method for grading internal artery stenosis. PATIENTS AND METHODS: Duplex scans and arteriograms of carotid arteries of 142 patients were reviewed. Peak and end-diastolic velocities of the common and internal carotid arteries were recorded, and the percent stenosis of the internal carotid artery was determined by arteriogram. Receiver-operator characteristic curves of sensitivity, specificity, positive and negative predictive values and accuracy were determined. RESULTS: The recommended criteria for the detection of ≥70% stenosis of the internal carotid artery were: peak systolic velocity in the internal carotid artery ≥215 cm/s, end-diastolic velocity in the internal carotid artery ≥65 cm/s, ratio of peak systolic velocities in the internal and common carotid arteries ≥2.7 and ratio of the end-diastolic velocities of the internal and common carotid arteries ≥3.7. CONCLUSION: These criteria allow for reliable determination of internal carotid artery stenosis ≥70% by duplex ultrasound.
- MeSH
- arteria carotis interna diagnostické zobrazování MeSH
- dospělí MeSH
- duplexní dopplerovská ultrasonografie metody MeSH
- lidé středního věku MeSH
- lidé MeSH
- prediktivní hodnota testů MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- senzitivita a specificita MeSH
- stenóza arteria carotis diagnóza MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- infarkt myokardu chirurgie ultrasonografie MeSH
- lidé MeSH
- ruptura komorového septa chirurgie MeSH
- srdeční katetrizace MeSH
- zaváděcí katétry využití MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
- MeSH
- arteria subclavia patofyziologie patologie MeSH
- lidé MeSH
- nemoci arterie carotis diagnóza terapie MeSH
- syndromy aortálního oblouku diagnóza klasifikace terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- recenze MeSH
Čtyřiašedesátiletá žena s akutním IM pravé komory (IMPK) v kombinaci s IM spodní stěny byla přijata na JIP spádového interního oddělení a léčena antiagregancii, heparinem, intenzivní volumoterapií a katecholaminy. Progredovala hypotenze, rozvinulo se akutní oligurické selhání ledvin a počínající selhání jater. Druhý den pacientka přeložena na KJ interní kliniky, kde provedena PCI s rekanalizací a stentingem vysokého uzávěru ACD, pokračováno v masivním přívodu tekutin a katecholaminové podpoře, provedena CVVHD a dočasná kardiostimulace z pravé síně. Obnovena diuréza, stabilizován krevní tlak, v dalších dnech postupná normalizace laboratorních parametrů, pohybová rehabilitace. Po propuštění do domácího léčení postupná úprava fyzické výkonnosti a volumových a kontraktilních parametrů obou srdečních komor. Dle některých literárních údajů zůstává při infarktu pravé komory zachována viabilita jejího myokardu a výkonnost pravé komory se zlepšuje a posléze upravuje i bez časné reperfuze. Údaje o provedení a efektu časné reperfuze při IMPK jsou dosud výrazně méně časté než u infarktu levé komory. U těžkého IMPK se vznikem multiorgánového selhání je direktní PCI v kombinaci s další terapií postupem k odvrácení jinak zřejmě fatálního průběhu.
A 64-year-old woman with acute right ventricular myocardial infarction (RVMI) in combination with inferior wall myocardial infarction was admitted to the intensive care unit of her catchment area hospital and treated with antiaggregants, heparin intensive volume therapy, and catecholamines. On the following day, the patient was transferred to the coronary unit of terciary center where PCI with recanalization and stenting of the right coronary artery was performed, massive fluid administration and catecholamine support were continued and CVVHD and temporary right atrial based cardiac stimulation were performed. Diuresis was re-established and blood pressure was stabilized, in the following days laboratory parameters gradually returned to normal and physical rehabilitation was initiated. Following discharge, physical performance as well as volume and contractile parameters of both ventricles improved over time. According to the literature, in right ventricular infarction the viability of the myocardium remains preserved and the efficiency of the right ventricle improves and subsequently settles even without early reperfusion. The data on performing and effects of early reperfusion in RVMI have been less frequent than in the case of left ventricular infarction. In severe RVMI with multiorgan failure, direct PCI in combination with other therapeutic procedures is the method to reverse an otherwise apparently fatal course.
- MeSH
- balónková koronární angioplastika MeSH
- funkce pravé komory srdeční MeSH
- infarkt myokardu farmakoterapie MeSH
- lidé MeSH
- multiorgánové selhání MeSH
- péče o pacienty v kritickém stavu MeSH
- rehabilitace MeSH
- stenty MeSH
- syndrom omráčeného myokardu MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
- Publikační typ
- abstrakt z konference MeSH
- MeSH
- Borrelia burgdorferi patogenita MeSH
- elektrofyziologické techniky kardiologické metody MeSH
- endokarditida diagnóza etiologie terapie MeSH
- lymeská nemoc diagnóza etiologie farmakoterapie MeSH
- myokarditida diagnóza etiologie terapie MeSH
- nemoci srdce diagnóza etiologie terapie MeSH
- Publikační typ
- přehledy MeSH
