• MeSH
• Adrenergic alpha-Agonists pharmacology   therapeutic use   MeSH
• Ambulatory Care methods   MeSH
• Estriol pharmacology   therapeutic use   MeSH
• Gynecological Examination methods   MeSH
• Weight Loss MeSH
• Urinary Tract Infections drug therapy   prevention & control   MeSH
• Urinary Incontinence * diagnosis   etiology   therapy   MeSH
• Humans MeSH
• Pelvic Floor pathology   MeSH
• Pessaries MeSH
• Rehabilitation methods   MeSH
• Urinary Incontinence, Stress drug therapy   MeSH
• Urinary Incontinence, Urge drug therapy   MeSH
• Check Tag
• Humans MeSH
• Female MeSH

• Keywords
• pesaroterapie,
• MeSH
• Urinary Incontinence surgery   therapy   MeSH
• Humans MeSH
• Pelvic Floor physiopathology   MeSH
• Pessaries * history   adverse effects   MeSH
• Pelvic Organ Prolapse * surgery   therapy   MeSH
• Check Tag
• Humans MeSH
• Female MeSH

• MeSH
• Gynecologic Surgical Procedures methods   MeSH
• Humans MeSH
• Pessaries MeSH
• Pelvic Organ Prolapse * diagnosis   therapy   MeSH
• Physical Therapy Modalities MeSH
• Check Tag
• Humans MeSH
• Female MeSH
• Publication type
• Review MeSH

INTRODUCTION AND HYPOTHESIS: Members of the International Urogynecological Association (IUGA) come from different geographic locations and practice settings. A member survey regarding practice patterns provides valuable information for practitioners and researchers alike, and allows the IUGA to discover areas to focus on education and information dissemination. METHODS: A questionnaire was developed by the IUGA Research and Development committee and distributed electronically to IUGA surgeons. Answers were analyzed in reference to demographics, geographic distribution, and academic affiliation. RESULTS: Five hundred sixty-four members answered the questionnaire, representing a 28 % response rate, and closely reflecting the geographic distribution of IUGA membership. Preferred surgical treatment for uncomplicated SUI was the mid-urethral trans-obturator sling (49.7 %). Vaginal mesh was mainly used for repair of recurrent POP (20.4 %). Pessary use was offered "always" or "frequently" by 61.5 %, with no difference in academic affiliation, but significant differences based on region of practice. Compared to practitioners in non-academic centers, those with academic affiliation utilized Urodynamic studies (UDS) and Magnetic Resonance Imaging (MRI) more frequently in the evaluation of POP. Regions of practice significantly influenced the majority of practice patterns, with the highest impact found in the use of robotic assistance. CONCLUSIONS: Many practice patterns in the evaluation and treatment of POP and SUI depend on academic affiliation and geographic location. Practice patterns are not always based on most recent evidence-based data.

• MeSH
• Surgical Mesh utilization   MeSH
• Adult MeSH
• Gynecology statistics & numerical data   MeSH
• Internationality MeSH
• Practice Patterns, Physicians' statistics & numerical data   MeSH
• Middle Aged MeSH
• Humans MeSH
• Magnetic Resonance Imaging utilization   MeSH
• Young Adult MeSH
• Pessaries utilization   MeSH
• Pelvic Organ Prolapse surgery   MeSH
• Surveys and Questionnaires MeSH
• Urinary Incontinence, Stress surgery   MeSH
• Suburethral Slings utilization   MeSH
• Ultrasonography utilization   MeSH
• Urology statistics & numerical data   MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Young Adult MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH

• Keywords
• POP-Q, vaginální sítě,
• MeSH
• Endosonography MeSH
• Humans MeSH
• Pelvic Floor anatomy & histology   diagnostic imaging   pathology   MeSH
• Pessaries MeSH
• Pelvic Organ Prolapse * diagnosis   etiology   classification   therapy   MeSH
• Risk Factors MeSH
• Plastic Surgery Procedures adverse effects   MeSH
• Check Tag
• Humans MeSH
• Female MeSH
• Publication type
• Review MeSH

Experimentální studie nových vaginálních globulí Melanizol? a Klimedeks? byla provedena na modelu experimentální vaginitidy u potkanů vyvolané směsí terpentýnové silice a dimethylsulfoxidu. Získaná experimentální data ukazují, že vaginální globule Melanizol? a Klimedeks? vykazovaly 5. a 8. den experimentu významně vyšší terapeutický efekt ve srovnání s kontrolní skupinou a skupinou užívající placebo v oblasti obnovení fyziologických funkcí a kumulace glykogenu ve vaginální sliznici. Melanizol? a Klimedeks? překovaly v účinku referenční přípravky globule Gravagin? a globule s Hippophaes oleum, ale byly méně účinné ve srovnání s referenčním přípravkem vaginální tablety Micogynax? ve sledovaných kritériích.

The experimental studies of the new vaginal pessaries Melanizol? and Klimedeks? have been carried out on the model of experimental vaginitis induced in rats by a mixture of terebenthine oil and dimethyl sulfoxide. The obtained experimental data indicate that the vaginal pessaries Melanizol? and Klimedeks? on the background of experimental vaginitis have a therapeutic effect on the 5th and 8th days of the experiment, significantly surpassing the group of animals of control pathology and placebo in its ability to restore physiological functions and accumulate glycogen by the vaginal epithelium. Melanizol? and Klimedeks? have significantly surpassed the reference drugs, the pessaries Gravagin? and Hippophaes oleum, but have been less efficient in the activity to the reference drug, the vaginal tablets Micogynax? on this criterion

• Keywords
• Melanizol, Klimedeks,
• MeSH
• Endometrium anatomy & histology   diagnostic imaging   MeSH
• Glycogen MeSH
• Rats * MeSH
• Disease Models, Animal MeSH
• Pessaries utilization   MeSH
• Vaginal Creams, Foams, and Jellies therapeutic use   MeSH
• Vaginitis * diagnosis   therapy   MeSH
• Animals MeSH
• Check Tag
• Rats * MeSH
• Animals MeSH

• MeSH
• Urinary Bladder, Overactive MeSH
• Urinary Incontinence * physiopathology   MeSH
• Humans MeSH
• Pelvic Floor Disorders epidemiology   surgery   rehabilitation   MeSH
• Pelvic Floor * anatomy & histology   physiology   MeSH
• Pessaries utilization   MeSH
• Pelvic Organ Prolapse * etiology   classification   physiopathology   MeSH
• Urinary Incontinence, Stress MeSH
• Check Tag
• Humans MeSH
• Female MeSH
• Publication type
• Review MeSH

• MeSH
• Cerclage, Cervical MeSH
• Cervix Uteri anatomy & histology   diagnostic imaging   MeSH
• Uterine Cervical Incompetence diagnostic imaging   drug therapy   prevention & control   MeSH
• Pregnancy Complications MeSH
• Humans MeSH
• Pessaries utilization   MeSH
• Premature Birth etiology   prevention & control   MeSH
• Progesterone administration & dosage   MeSH
• Pregnancy MeSH
• Drug Administration Routes MeSH
• Check Tag
• Humans MeSH
• Pregnancy MeSH
• Female MeSH

INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse (POP) in pregnancy is a rare condition with decreasing incidence and improved management and outcome world-wide recently. Systematic review of the literature for cases of POP in pregnancy published since 1990 was carried out to identify common factors in presentation, management and outcomes. One case from our own practice was added to the analysis. METHODS: An extensive search of the Pubmed/Medline, Scopus and Google Scholar databases was performed to identify all cases of POP in pregnancy since 1990. Published case reports of POP in pregnancy were reviewed and summarized in tables to find similarities in history, course, management and outcome of the pregnancies. RESULTS: Of the 43 cases and one case series, 41 case studies were eligible for analysis. Two types of POP in pregnancy were identified: preexisting is less common (14 vs 27 cases), often resolves during pregnancy (5 out of 14) and always recurs after delivery (14 out of 14); acute onset of POP in pregnancy rarely resolves in pregnancy (2 out of 27), but often resolves after delivery (18 out of 27). Most patients were managed with bed rest (20 out of 41), pessary (15 out of 41), manual reduction (6 out of 41) and local treatment (6 out of 41). The most common complications reported include preterm labour (14 out of 41), cervical ulcerations (9 out of 41), infection (3 out of 41) and obstructed labour (4 out of 41). About a half of the women delivered vaginally (22 out of 41), caesarean section due to prolapse was required in 15 cases. CONCLUSIONS: Two distinct entities were identified based on similarities regarding onset, course and outcome of POP in pregnancy. Concise recommendations for practice were derived from the analysis of case studies published since 1990.

• MeSH
• Cesarean Section MeSH
• Dystocia etiology   MeSH
• Pregnancy Complications, Infectious etiology   MeSH
• Bed Rest MeSH
• Pregnancy Complications etiology   MeSH
• Humans MeSH
• Pessaries MeSH
• Obstetric Labor, Premature etiology   MeSH
• Pelvic Organ Prolapse complications   diagnosis   therapy   MeSH
• Pregnancy MeSH
• Check Tag
• Humans MeSH
• Pregnancy MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH
• Review MeSH

• MeSH
• Middle Aged MeSH
• Humans MeSH
• Pelvic Floor * abnormalities   physiology   MeSH
• Pessaries * history   utilization   MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Female MeSH