- MeSH
- ANCA-asociované vaskulitidy * farmakoterapie komplikace MeSH
- glomerulonefritida * komplikace MeSH
- křehký senior MeSH
- ledviny MeSH
- lidé MeSH
- protilátky proti cytoplazmě neutrofilů MeSH
- rituximab terapeutické užití MeSH
- senioři MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
A description of clinical course of 4 patients diagnosed and treated in our department with fibrillary GN is given. Fibrillary GN and immunotactoid glomerulopathy are entities, characterized by fibrillar and microtubular deposits in mesangium and the glomerular capillary loops. At our nephrologic division 4 cases of patients with fibrillary GN were diagnozed by the end of the year 2001. Renal biopsy was indicated for proteinuria, hematuria and decrease of renal function. Histologic features observed in light microscopy and immunofluorescency were non–diagnostic; fibrillary character of deposits compatible with the diagnosis of fibrillary GN was proven by electron microscopy. During several months follow–up proteinuria and/or renal insufficiency progressed, despite immunosuppressive treatment. On conclusion: though fibrillary GN/ immunotactoid GN are relatively rare disorders, they represent entities, which should not be omitted in the differential diagnosis of nephrotic syndrome/renal insufficiency, while prognosis remain rather unfavourable and optimal therapy is controversial.
- MeSH
- glomerulární mesangium patologie MeSH
- glomerulonefritida diagnóza klasifikace terapie MeSH
- imunosupresivní léčba využití MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- kongresy MeSH
- MeSH
- amyloidóza patologie MeSH
- glomerulonefritida diagnóza etiologie terapie MeSH
- imunoglobuliny škodlivé účinky MeSH
- imunosupresivní léčba metody využití MeSH
- lidé MeSH
- přežívání štěpu imunologie účinky léků MeSH
- transplantace ledvin patologie škodlivé účinky MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- souhrny MeSH
