BACKGROUND: Psychotic-like experiences (PLEs) are subtle, subclinical perturbations of perceptions and thoughts and are common in the general population. Their characterisation and unidimensionality are still debated. METHODS: This study was conducted by the Electronic-halluCinations-Like Experiences Cross-culTural International Consortium (E-CLECTIC) and aimed at measuring the Community Assessment of Psychic Experiences (CAPE) factorial structure across five European countries (Belgium; Czech Republic, Germany; Greece, and Spain) and testing the adequacy of the unidimensional polytomous Rasch model of the tool via Partial Credit Model (PCM) of the CAPE to detect people with a high risk for developing psychosis. RESULTS: The sample included 1461 participants from the general population. The factorial analysis confirmed the best fit for the bifactor implementation of the three-factor model, including the positive, negative and depressive dimensions and a general factor. Moreover, the unidimensional polytomous Rasch analysis confirmed that CAPE responses reflected one underlying psychosis proneness. CONCLUSIONS: The study proved that the CAPE measures a single latent dimension of psychosis-proneness. The CAPE might help locate and estimate psychosis risk and can be used as a screening tool in primary care settings/education settings.

• MeSH
• dospělí MeSH
• faktorová analýza statistická MeSH
• halucinace diagnóza   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• psychiatrické posuzovací škály normy   MeSH
• psychometrie * normy   MeSH
• psychotické poruchy * diagnóza   psychologie   MeSH
• srovnání kultur MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Belgie MeSH
• Česká republika MeSH
• Evropa MeSH
• Německo MeSH
• Řecko MeSH
• Španělsko MeSH

BACKGROUND: Innovative uses of mobile health (mHealth) technology for real-time measurement and management of epilepsy may improve the care provided to patients. For instance, seizure detection and quantifying related problems will have an impact on quality of life and improve clinical management for people experiencing frequent and uncontrolled seizures. Engaging patients with mHealth technology is essential, but little is known about patient perspectives on their acceptability. The aim of this study was to conduct an in-depth qualitative analysis of what people with uncontrolled epilepsy think could be the potential uses of mHealth technology and to identify early potential barriers and facilitators to engagement in three European countries. METHOD: Twenty people currently experiencing epileptic seizures took part in five focus groups held across the UK, Italy, and Spain. Participants all completed written consent and a demographic questionnaire prior to the focus group commencing, and each group discussion lasted 60-120 min. A coding frame, developed from a systematic review of the previous literature, was used to structure a thematic analysis. We extracted themes and subthemes from the discussions, focusing first on possible uses of mHealth and then the barriers and facilitators to engagement. RESULTS: Participants were interested in mHealth technology as a clinical detection tool, e.g., to aid communication about seizure occurrence with their doctors. Other suggested uses included being able to predict or prevent seizures, and to improve self-management. Key facilitators to engagement were the ability to raise awareness, plan activities better, and improve safety. Key barriers were the potential for increased stigma and anxiety. Using familiar and customizable products could be important moderators of engagement. CONCLUSION: People with uncontrolled epilepsy think that there is a scope for mHealth technology to be useful in healthcare as a detection or prediction tool. The costs will be compared with the benefits when it comes to engagement, and ongoing work with patients and other stakeholders is needed to design practical resources.

• MeSH
• dospělí MeSH
• epilepsie terapie   MeSH
• komunikace * MeSH
• kvalita života MeSH
• lidé středního věku MeSH
• lidé MeSH
• management nemoci MeSH
• mladý dospělý MeSH
• pacientův souhlas se zdravotní péčí * MeSH
• postoj ke zdraví MeSH
• self-management * MeSH
• telemedicína * MeSH
• vztahy mezi lékařem a pacientem * MeSH
• záchvaty MeSH
• zakotvená teorie MeSH
• zapojení pacienta MeSH
• zjišťování skupinových postojů MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Itálie MeSH
• Španělsko MeSH
• Spojené království MeSH

Given probable the increment in the nutritional needs of both humans and animals, animal production will have increased dramatically by 2050. Insect meals could be an alternative protein source for livestock, and they would also be able to reduce the environmental problems related to intensive animal production system. The aim of this study was to evaluate productive performance, blood analysis, nutrient digestibility, and changes in the internal organs of laying hens fed Hermetia illucens larvae meal (HI) at two different levels in substitution (25 or 50%) of soybean meal (SBM). A total of 162 Hy-line Brown hens (sixteen weeks old) were equally divided into three experimental groups and fed isoprotein and isoenergetic diets. Egg weight, feed intake, and feed conversion rate were not affected by the soybean meal substitution at both inclusion levels of insect meal. Egg mass was positively affected by the insect meal diets, as was the lay percentage, although only at the lowest inclusion level. Dry matter, organic matter, and crude protein digestibility coefficients were lower for the HI50 diet, probably due to the negative effect of chitin. A reduction in serum cholesterol and triglycerides was observed in both insect-meal fed groups, while serum globulin level increased only at the highest level of insect meal inclusion, and, consequently, the albumin to globulin ratio decreased. Overall, a protein replacement of 25% with an insect meal from Hermetia illucens larvae in the diet of laying hens seems to be more suitable and closer to the optimal level.

• MeSH
• dieta veterinární   MeSH
• Diptera * MeSH
• fyziologie výživy zvířat MeSH
• Glycine max MeSH
• krmivo pro zvířata analýza   MeSH
• kur domácí fyziologie   MeSH
• larva MeSH
• nutriční hodnota MeSH
• triglyceridy MeSH
• živiny MeSH
• zvířata MeSH
• Check Tag
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

BACKGROUND: Mobile technology has the potential to provide accurate, impactful data on the symptoms of depression, which could improve health management or assist in early detection of relapse. However, for this potential to be achieved, it is essential that patients engage with the technology. Although many barriers to and facilitators of the use of this technology are common across therapeutic areas and technology types, many may be specific to cultural and health contexts. OBJECTIVE: This study aimed to determine the potential barriers to and facilitators of engagement with mobile health (mHealth) technology for remote measurement and management of depression across three Western European countries. METHODS: Participants (N=25; 4:1 ratio of women to men; age range, 25-73 years) who experienced depression participated in five focus groups held in three countries (two in the United Kingdom, two in Spain, and one in Italy). The focus groups investigated the potential barriers to and facilitators of the use of mHealth technology. A systematic thematic analysis was used to extract themes and subthemes. RESULTS: Facilitators and barriers were categorized as health-related factors, user-related factors, and technology-related factors. A total of 58 subthemes of specific barriers and facilitators or moderators emerged. A core group of themes including motivation, potential impact on mood and anxiety, aspects of inconvenience, and ease of use was noted across all countries. CONCLUSIONS: Similarities in the barriers to and facilitators of the use of mHealth technology have been observed across Spain, Italy, and the United Kingdom. These themes provide guidance on ways to promote the design of feasible and acceptable cross-cultural mHealth tools.

• Publikační typ
• časopisecké články MeSH

BACKGROUND: In time, we may be able to detect the early onset of symptoms of depression and even predict relapse using behavioural data gathered through mobile technologies. However, barriers to adoption exist and understanding the importance of these factors to users is vital to ensure maximum adoption. METHOD: In a discrete choice experiment, people with a history of depression (N = 171) were asked to select their preferred technology from a series of vignettes containing four characteristics: privacy, clinical support, established benefit and device accuracy (i.e., ability to detect symptoms), with different levels. Mixed logit models were used to establish what was most likely to affect adoption. Sub-group analyses explored effects of age, gender, education, technology acceptance and familiarity, and nationality. RESULTS: Higher level of privacy, greater clinical support, increased perceived benefit and better device accuracy were important. Accuracy was the most important, with only modest compromises willing to be made to increase other factors such as privacy. Established benefit was the least valued of the attributes with participants happy with technology that had possible but unknown benefits. Preferences were moderated by technology acceptance, age, nationality, and educational background. CONCLUSION: For people with a history of depression, adoption of technology may be driven by the desire for accurate detection of symptoms. However, people with lower technology acceptance and educational attainment, those who were younger, and specific nationalities may be willing to compromise on some accuracy for more privacy and clinical support. These preferences should help shape design of mHealth tools.

• MeSH
• deprese * diagnóza   terapie   MeSH
• lidé MeSH
• pacientova volba MeSH
• stupeň vzdělání MeSH
• telemedicína * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH

28 patients with scoliotic spine deformations were examined and operated. Correction at 12 patients was carried out with application of double-sided tool system, at 16 patients - with application of the single sided one. The best indicators of a functional outcome are noted at the installation of single sided design on the convex side of deformation.

• MeSH
• délka operace MeSH
• design vybavení MeSH
• fúze páteře * metody   statistika a číselné údaje   škodlivé účinky   MeSH
• interní fixátory MeSH
• krvácení při operaci statistika a číselné údaje   MeSH
• lidé MeSH
• následné studie MeSH
• ortopedické fixační pomůcky * MeSH
• pooperační komplikace MeSH
• rotace MeSH
• skolióza * chirurgie   radiografie   MeSH
• výsledek terapie MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• srovnávací studie MeSH

Cíl: Shrnout výsledky souboru pacientů používajících implantabilní sluchový systém Baha (Bone anchored hearing aid; Baha) využívající princip kostního vedení pro kompenzaci jednostranné hluchoty (Single-Sided Deafness; SSD), bez ohledu na etiologii, která může být vrozená, vaskulární (náhlá percepční nedoslýchavost; Sudden Sensorineural Hearing Loss; SSNHL), infekční, traumatická, nádorová nebo iatrogenní. Soubor a metodika: V období od září 2010 do srpna 2014 bylo vyšetřeno a do studie zařazeno 59 pacientů s SSD. Etiologií SSD byla náhlá percepční nedoslýchavost, fraktura pyramidy, ototoxické působení léčby, úraz ucha, chronická otitida i růst vestibulárního schwannomu. Výsledky: Všichni pacienti si vyzkoušeli efekt pomocí Baha Softbandu a 23 z nich se rozhodlo pro Baha implantaci. V průběhu studie byly použity tři generace Baha implantátů (BI300, BIA400, Attract), bez peroperačních či pooperačních komplikací. Efektivita Baha byla prokázána při testování větné srozumitelnosti v šumu, kdy v odstupu šesti týdnů i jednoho roku dochází k signifikantnímu zlepšování výsledků za situace, že signál přichází ze strany hluchého ucha a šum ze strany normálně slyšícího, na hladině hlasitosti 65 dB SPL, resp. 70 dB SPL. Závěry: Baha je efektivní možnost kompenzace pacientů s SSD a nabídnutí i vyzkoušení implantabilních a/nebo nechirurgických možností kompenzace by mělo být samozřejmou součástí péče o pacienty s jednostrannou hluchotou.

Aim: To summarize data for the Baha (Bone anchored hearing aid) implantable hearing system based on the principle of bone conduction for the single-sided deafness (SSD) compensation, regardless of aetiology that may be congenital, vascular (Sudden Sensorineural Hearing Loss; SSNHL), infectious, traumatic, tumorous or iatrogenous. Patients and methodology: 59 patients with an SSD were examined between September 2010 and August 2014 and included into the study. The SSD aetiology included sudden hearing loss, temporal bone fracture, ototoxic effects of a treatment, chronic otitis and a growing vestibular schwannoma. Results: All patients were tested for the effect by the Baha Softband and 23 decided to undergo the surgery. During the entire course of the study, three generations of the Baha implants were used (BI300, BIA400, Attract) without any intraoperative or postoperative complications. The effectivity of the Baha system was shown during testing of a sentence comprehension in noise, with a significant improvement after six weeks and one year respectively. In this testing, the signal was coming to the deaf side and noise to the hearing side, on a loudness level of 65 dB SPL and 70 dB SPL, respectively. Conclusion: Baha represents an effective option for correction of patients with SSD. Patients should be offered to test an implantable and/or non-surgical options for compensation as part of routine care for patients with single-sided deafness.

• Klíčová slova
• jednostranná hluchota, větná srozumitelnost v šumu, Softband,
• MeSH
• audiometrie slovní statistika a číselné údaje   MeSH
• dospělí MeSH
• hluchota diagnóza   etiologie   chirurgie   MeSH
• implantace protézy metody   MeSH
• jednostranná nedoslýchavost * diagnóza   etiologie   chirurgie   MeSH
• kostní vedení zvuku * MeSH
• lidé středního věku MeSH
• lidé MeSH
• lokalizace zvuku MeSH
• mladiství MeSH
• mladý dospělý MeSH
• otologické chirurgické výkony MeSH
• percepce řeči fyziologie   MeSH
• senioři MeSH
• sluchové pomůcky * MeSH
• spokojenost pacientů statistika a číselné údaje   MeSH
• výsledek terapie MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• práce podpořená grantem MeSH

Úvod: Jednostranná hluchota (single sided deafness – SSD) je charakterizovaná sluchovou ztrátou na jednom uchu (pure tone average – PTA – 70 dB HL a více) při prakticky normálním sluchu na druhém uchu (ztráty do 30 dB HL). Jedním ze způsobů řešení je kochleární implantace, která na rozdíl od jiných kompenzačních mechanizmů (CROS systém, systémy pro přímé kostní vedení) jako jediná umožňuje binaurální slyšení. Materiál a metodika: Do studie bylo zahrnuto 6 dětských pacientů s dg. SSD, kteří podstoupili kochleární implantaci ve FN Motol v letech 2020–2021. Sledovali jsme rozvoj sluchové percepce s kochleárním implantátem, schopnost směrového slyšení a průměrnou denní dobu používání zvukového procesoru. Výsledky: Všichni pacienti používají zvukový procesor pravidelně, u všech se subjektivně i objektivně zlepšila sluchová percepce. Směrové slyšení zatím není prokazatelné. Pacienty budeme nadále sledovat a získané poznatky bude třeba do budoucna ověřit na rozsáhlejším souboru. Závěr: Kochleární implantace může být vhodným způsobem řešení jednostranné hluchoty u dětí. Při indikaci je nutno zvažovat etiologii sluchové vady, délku trvání hluchoty a motivaci dítěte a jeho rodičů k pravidelnému užívání zvukového procesoru

Introduction: Single-sided deafness (SSD) is characterized by hearing loss in one ear (pure tone average – PTA – 70 dB HL and more) with practically normal hearing in the other ear (losses up to 30 dB HL). One of the solutions is cochlear implantation, which, unlike other compensatory mechanisms (CROS system, direct bone conduction systems), is the only one that enables binaural hearing. Material and methods: Six pediatric patients with SSD who underwent cochlear implantation at FN Motol in 2020–2021 were included in the study. We monitored the development of auditory perception with a cochlear implant, the ability of directional hearing and the average daily time of use of the sound processor. Results: All patients use the sound processor regularly, subjectively and objectively their hearing perception improved. Directional hearing is not yet demonstrable. We will continue to monitor the patients and the knowledge gained will need to be verified on a larger set in the future. Conclusion: Cochlear implantation can be a suitable way to solve unilateral deafness in children. When indicating, it is necessary to consider the etiology of the hearing defect, the duration of the deafness, and the motivation of the children and their parents to regularly use the sound processor.

• MeSH
• audiometrie MeSH
• dítě MeSH
• jednostranná nedoslýchavost * diagnóza   etiologie   terapie   MeSH
• kochleární implantace * MeSH
• lidé MeSH
• mladiství MeSH
• percepce řeči MeSH
• předškolní dítě MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• předškolní dítě MeSH
• ženské pohlaví MeSH
• Publikační typ
• kazuistiky MeSH

Úvod: Bonebridge je aktivní implantabilní systém pro přímé kostní vedení. Cílem práce je prezentace pilotních výsledků rehabilitace jednostranné hluchoty pomocí tohoto systému. Materiál a metodika: Jsou analyzovány případy tří pacientů s jednostrannou hluchotou, kteří podstoupili v roce 2018 implantaci Bonebridge na Klinice otorinolaryngologie a chirurgie hlavy a krku Fakultní nemocnice u sv. Anny v Brně. Parametry hodnocení: dotazník Bern Benefit in Single-Sided Deafness Questionnaire, experimentální vyšetření prostorového slyšení a test větné srozumitelnosti v hovorovém šumu. Výsledky: Dotazník: v rámci vizuální analogové škály v rozmezí –5 až +5 bodů bylo průměrné hodnocení +2,4 bodu, tedy poslech byl hodnocen jako jednodušší s Bonebridge než bez sluchové pomůcky. Schopnost lokalizace zdroje zvuku byla hodnocena u dvou dotazovaných 0–1 bodem, u jednoho dotazovaného 4 body. Vyšetření prostorového slyšení: bez sluchové pomůcky byla u všech vyšetřovaných schopnost lokalizace zdroje zvuku významně zhoršena. S Bonebridge byla při tolerované odchylce 45° úspěšnost lokalizace zdroje zvuku 75–100 % v rozsahu 0°–360° v horizontální rovině. Test větné srozumitelnosti v hovorovém šumu: největšího zlepšení srozumitelnosti (o 30–100 %) bylo s Bonebridge dosaženo při SNR –5 dB. Závěr: Pomocí Bonebridge není možné u pacientů s jednostrannou hluchotou nahradit binaurální slyšení, jedná se o tzv. pseudobinaurální korekci. Podobně jako jiné implantabilní systémy pro kostní vedení přináší Bonebridge u pacientů s jednostrannou hluchotou benefit v řadě poslechových situací. Pomocí experimentálních audiologických testů byl zjištěn přínos Bonebridge pro rozumění větám v akustickém šumu a zlepšení schopnosti lokalizace zdroje zvuku. Validace výsledků by však vyžadovala větší počet probandů.

Introduction: Bonebridge is a direct bone conduction hearing implantable system. The aim of the work is to present pilot results of rehabilitation of single sided deafness using this system. Material and methods: Analysis of three patients with single-sideded deafness, who underwent BB implantation in 2018 at the Department of Otorhinolaryngology and Head and Neck Surgery of St. Anna Hospital in Brno. Evaluation parameters: Bern Benefit in Single-Sided Deafness Questionnaire, experimental examination of directional hearing and hearing in noise test. Results: Questionnaire: Within the visual analog scale in the range of –5 to +5 points, the average rating was + 2.4 points, so listening was rated as easier with Bonebridge than without hearing aids. The ability to locate the sound source was evaluated by 4 and 0–1 points in one and two respondents, respectively. Examination of spatial hearing: without hearing aid, the ability to locate the sound source was significantly impaired in all the examined. With Bonebridge, with a tolerated deviation of 45°, the success rate of sound source localization was 75–100% in the range of 0–360° in the horizontal plane. Hearing in noise test: the greatest improvement in intelligibility (by 30–100%) was achieved with Bonebridge at SNR –5 dB. Conclusion: Bonebridge is not able to restore binaural hearing in patients with single sided deafness, it is a pseudo-binaural correction. Like other implantable bone conduction systems, Bonebridge is benefitial for patients with single sided deafness in a variety of listening situations. Using experimental audiological tests, the contribution of Bonebridge to understanding sentences in acoustic noise and improving the ability to locate the sound source was found. However, validation of the results would require a larger number of probands.

• Klíčová slova
• Bonebridge,
• MeSH
• dospělí MeSH
• jednostranná nedoslýchavost * rehabilitace   terapie   MeSH
• kostní vedení zvuku * MeSH
• lidé středního věku MeSH
• lidé MeSH
• percepce řeči MeSH
• pilotní projekty MeSH
• průzkumy a dotazníky MeSH
• sluchové pomůcky MeSH
• test prahu recepce řeči metody   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• kazuistiky MeSH

PURPOSE OF THE STUDY: A comparison of radiological and clinical results between dorsal pelvic segment stabilization with a transiliac internal fixator (TIFI) and that with two iliosacral screws (IS). MATERIAL AND METHODS: In this prospective study, both the TIFI and the IS group had 32 patients. The majority of injuries were assessed as type C1.3 because only patients with a high-energy mechanism of injury were included. Radiological results were evaluated according to the Matta scoring system and clinical outcome using the Majeed score and the Pelvic Outcome Score. Categorical data were evaluated by the two-sided Fisher's exact test or Pearson's χ2 test and continuous data by Student's t-test. A test result with p<0.05 was considered statistically significant. RESULTS: In the TIFI group, the mean posterior displacement was 2.2 mm, in the IS group it was 1.9 mm (p=0.58542). The pelvic outcome scores in the TIFI group were: excellent, 28%; good, 12%; fair, 48.0%; and poor, 4 %; in the IS group they were: excellent, 11.1%; good, 22.2%; fair, 66.7%; and poor, 0.0% (p=0.51731). The Majeed scores were as follows: excellent, 56.0%; good, 16.0%; fair, 20.0%; poor 8.0 % for the TIFI group and excellent, 50.0%; good, 27.8%; fair, 11.1%; and poor, 11.1% for the IS group (p=0.70187). Within the total, average Majeed score was 80.64 points in TIFI, 80.67 in IS (p=0.99654). In a sub-analysis of unilateral transforaminal fractures (Pohlemann type II), the average score for TIFI was 82.8 points and only 53.5 points for IS; the differences were statistically significant (p=0.04517). No intraoperative complications were associated with TIFI and one injury to the superior gluteal artery (3.1%) and two iatrogenic neurological injuries with IS (6.3%; p=0.23810). In the TIFI group, the fixator was removed without complications. In the IS group, post-operative wound bleeding following screw removal occurred in three patients (20.0%; p=0.22414), complete extraction of screws and washers was successful only in seven patients (46.7%), washers were left in situ in six patients (40.0 %) and IS removal was not possible in two patients (13.3%). The difference in complications between the groups was highly significant (p=0.00220). DISCUSSION: The results of our study are in agreement with those of the relevant studies published recently as well as with the outcomes of transiliac plate fixation reported in the literature. TIFI implantation is preferred in transforaminal and central sacral fractures because, unlike iliosacral screws, it carries a low risk of excessive compression of the sacral foramina and iatrogenic neurological injury. There were no significant differences in clinical and radiological findings between TIFI and IS procedures. Only in unilateral transforaminal fracture the TIFI stabilization had better outcome, as shown by the Majeed score. The IS fixation was associated with a higher rate of complications not only in primary implantation, but also at implant removal. CONCLUSIONS: The TIFI technique is superior to the IS procedure in fixation of unilateral transforaminal fractures and provides a reasonable alternative to the existing types of minimally invasive fixation.

• MeSH
• fraktury kostí radiografie   chirurgie   MeSH
• interní fixátory * MeSH
• kostní šrouby * MeSH
• lidé MeSH
• miniinvazivní chirurgické výkony přístrojové vybavení   metody   MeSH
• os ilium chirurgie   MeSH
• pánevní kosti zranění   radiografie   chirurgie   MeSH
• prospektivní studie MeSH
• vnitřní fixace fraktury přístrojové vybavení   metody   MeSH
• výsledek terapie MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• hodnotící studie MeSH
• srovnávací studie MeSH