1st ed. 18, 298 s.
- MeSH
- Biophysics MeSH
- Cell Membrane MeSH
- Publication type
- Monograph MeSH
- Conspectus
- Buněčná biologie. Cytologie
- NML Fields
- cytologie, klinická cytologie
- fyzika, biofyzika
We report a new approach to characterization of thin (bio)molecular films based on spectroscopy of Bragg-scattered surface plasmons (BSSPs) generated by diffraction-coupling of counterpropagating surface plasmons on a metal-coated diffraction grating. The BSSPs exhibit fields with different penetration depths into the medium adjacent to the metal and therefore exhibit unequal sensitivities to the presence of (bio)molecular films on the surface of the metal. Therefore, spectroscopy of BSSPs enables in situ observation of the formation of biomolecular films and determination of both their refractive index and thickness. We demonstrate this capacity of spectroscopy of BSSPs in a model experiment in which growth of protein layers on a gold surface is studied.
The use of untreated medical devices (catheters, endotracheal tubes) can lead to hospital-acquired infections. Antibacterial coatings of biocompatible polymers may reduce the risk of such infections. Silver nanolayers of different thickness were sputtered on polyimide (PI) and investigated both before and after thermal annealing. The electrical continuity of the layers was examined by sheet resistance. After sputtering, the layers become electrically continuous from an effective thickness of 11 nm. However, atomic force microscopy showed that the surface of the annealed samples underwent significant changes; they were transformed into discrete nanoislands and lost continuity completely. This phenomenon was supported by X-ray photoelectron spectroscopy which showed that the amount of Ag was reduced. The antibacterial properties of the as-sputtered and annealed samples were investigated by gram-negative and gram-positive bacterial strains. The inhibition of bacterial strains increased significantly after annealing. In general, our results suggest that Ag nanostructures are promising antibacterial coatings for polymeric medical devices.
- Keywords
- Kapton®,
- MeSH
- Anti-Bacterial Agents MeSH
- Biofilms MeSH
- Blood Vessel Prosthesis MeSH
- Imides MeSH
- Catheters MeSH
- Humans MeSH
- Nanostructures * MeSH
- Polymers MeSH
- Silver * therapeutic use MeSH
- Body Temperature Regulation MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
Current topics in pathology, ISSN 0070-2188 83, 1991
XII, 522 s. : il., tab.
- MeSH
- Biomedical Research MeSH
- Electric Stimulation MeSH
- Electromyography MeSH
- Hemiplegia physiopathology MeSH
- Humans MeSH
- Sciatic Nerve physiology MeSH
- Median Nerve physiology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Comparative Study MeSH
