INTRODUCTION: The communicating veins between the great and small saphenous veins, called intersaphenous veins, are often overlooked structures, except for the femoral intersaphenous vein (of Giacomini). The reason for tendency to neglect the crural intersaphenous veins can be their alleged high variability. The aim of the study was to bring reliable anatomical and morphometric data about the crural intersaphenous veins for their potential clinical usage as grafts. MATERIAL AND METHODS: In this ultrasonographic study performed on a young population, we screened 246 lower extremities. The incidence of the femoral intersaphenous vein was 51.2 % (126/246) and the incidence of at least one crural intersaphenous vein was 97.1 % (239/246). Two crural intersaphenous veins were observed in 46.7 % (115/246). RESULTS: The femoral intersaphenous vein was located exclusively on the thigh, with its average length of 26.35 cm and average calibre of 2.4 mm. The typical area where to find a crural intersaphenous vein is the middle medial part of the calf. Their course can be straight transverse, oblique or they can rarely make a plexus. The majority of intersaphenous veins of the leg do not possess valves, if so, those are parietal valves present in 10.3 % (39/379). An average length of 13.7 cm and an average calibre of 2.13 mm of intersaphenous veins of the leg are appropriate enough for their usage as a venous graft or in reconstruction surgery. CONCLUSION: The intersaphenous veins of the leg are not as variable as presented in previous studies. Their anatomical and topographical characteristics are fairly constant. According to their anatomical characteristics, crural intersaphenous veins could be surgically used as a suitable variant to the great saphenous vein, small saphenous vein and femoral intersaphenous vein.
- MeSH
- bérec * krevní zásobení diagnostické zobrazování anatomie a histologie MeSH
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- ultrasonografie MeSH
- vena femoralis anatomie a histologie diagnostické zobrazování MeSH
- vena saphena * diagnostické zobrazování anatomie a histologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
Arrhythmogenic cardiomyopathy is an inherited cardiomyopathy characterized by fibrofatty replacement and a high risk of ventricular arrhythmias and sudden cardiac death. This myocardial disorder is typically transmitted through autosomal dominant pattern and caused by pathogenic variants in the desmosomal and extradesmosomal genes. In this case, we are presenting a family with three members who have arrhythmogenic left ventricular cardiomyopathy. The condition was found to be caused by a nonsense mutation (c.1754 T>G (p. Leu585Ter)) in the desmoplakin (DSP) gene. Unfortunately, two of the family members were initially misdiagnosed and treated for coronary artery disease, which was not the correct diagnosis. This case demonstrates the importance of accurate differential diagnosis and the usefulness of magnetic resonance imaging (MRI) in establishing the correct diagnosis of arrhythmogenic cardiomyopathy.
- MeSH
- anamnéza MeSH
- chybná diagnóza MeSH
- desmoplakiny genetika MeSH
- genetické testování MeSH
- ischemická choroba srdeční diagnóza MeSH
- kardiologické zobrazovací techniky MeSH
- kardiomyopatie * diagnostické zobrazování genetika vrozené MeSH
- lidé MeSH
- mladý dospělý MeSH
- mutace MeSH
- srdeční komory abnormality MeSH
- vrozené srdeční vady * diagnostické zobrazování genetika patofyziologie MeSH
- Check Tag
- lidé MeSH
- mladý dospělý MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
- práce podpořená grantem MeSH
- MeSH
- dolní končetina anatomie a histologie krevní zásobení MeSH
- lidé MeSH
- vena saphena * anatomie a histologie MeSH
- vény * anatomie a histologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
Saphenopopliteal junction classification has been developing, but still the precise knowledge of junction type is crucial for proper surgical treatment. We examined the saphenopopliteal junction by duplex venous scanning in 244 extremities in healthy volunteers (median age: 23.0 years, 83 females, 39 male) and performed a meta-analysis of 13 studies focusing on structural types of the junction. According to Schweighoffer's classification we distinguished 5 types of the junction and we subdivided type A according to Cavezzi's classification of gastrocnemial veins termination into two. We added type F (small saphenous vein-SSV terminates into popliteal vein-PV), described especially in cadaveric studies. In our study, the most frequent type was A1 (96 cases), followed by C (70), B (48), A2 (20), E (6), D (3) and F (0). The pooled prevalence estimate for types A + B + D + E was 54.7% (95% CI 40.9-69.6%) and for type C 24.4% (95% CI 19.3-29.5%), whereas in 17.1% (95% CI 6.3-27.9%) of cases, the SSV terminated in the PV with no cranial extension present. The knowledge of the saphenopopliteal junction and its variations prevalence can help clinicians to quickly identify the real type of the junction during routine examination. In mid-European population, the main type is A1 and worldwide type A.
- MeSH
- duplexní dopplerovská ultrasonografie MeSH
- lidé MeSH
- mladý dospělý MeSH
- prediktivní hodnota testů MeSH
- vena poplitea * diagnostické zobrazování MeSH
- vena saphena * diagnostické zobrazování MeSH
- Check Tag
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- metaanalýza MeSH
- přehledy MeSH
- systematický přehled MeSH
Pagetův‐Schrötterův syndrom je označení pro idiopatickou trombózu horní končetiny. Toto vzácné onemocnění nejčastěji postihuje mladé muže, typicky po práci či sportu s horními končetinami nad hlavou. Anatomicky rozlišujeme několik prostorů, kde může dojít k útlaku nervově cévního svazku v oblasti regio cervicalis lateralis.
Paget-Schrötter syndrome is a rare syndrome of idiopathic thrombosis of the upper extremity. This syndrome most often occurs in young men. The provocative factor can be work or sport with elevation of upper extremities above the head. There are several spaces in the cervical lateral region where compression of nerve vascular bundle can occur. The combination of the coincidence of Paget-Schrötter syndrome as a cause of chronic thromboembolic pulmonary hypertension is rare. Both diagnoses require specific therapy. For Paget-Schrötter syndrome it is a surgical approach or rehabilitation together with pharmacological treatment. However, for chronic thromboembolic hypertension, it is a surgical approach or the combination of pharmacotherapy and balloon angioplasty. We present a case report of a young female patient in whom we dealt with the coincidence of these illnesses as well as the proper therapeutic management of both conditions.
- Klíčová slova
- riociguat,
- MeSH
- antikoagulancia aplikace a dávkování terapeutické užití MeSH
- balónková angioplastika MeSH
- CT angiografie MeSH
- dospělí MeSH
- dyspnoe etiologie MeSH
- hluboká žilní trombóza horní končetiny * diagnóza komplikace terapie MeSH
- lidé MeSH
- plicní hypertenze diagnóza etiologie terapie MeSH
- pyrazoly aplikace a dávkování terapeutické užití MeSH
- pyrimidiny aplikace a dávkování terapeutické užití MeSH
- tromboembolie diagnóza prevence a kontrola terapie MeSH
- trombolytická terapie metody MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
Infekční pseudoaneurysma aorty je rychle progredující onemocnění s vysokou mortalitou, pro něž je zásadní časná diagnostika a kombinovaná terapie. Symptomy jsou kombinací příznaků aortálního syndromu s elevací zánětlivých markerů. Základem terapie je několikatýdenní antibiotická terapie (ideálně cílená dle pozitivity hemokultur) v kombinaci s chirurgickou či endovaskulární terapií dle celkového stavu pacienta. Komplikací je ruptura pseudoaneurysmatu s fatálními následky, která je v závislosti na rychlosti progrese růstu pseudoaneurysmatu značným rizikem.
Infectious pseudoaneurysm of the aorta is a rapidly progressive disease with high mortality. Therefore, early diagnosis and combination therapy are crucial. The condition is manifested by signs of aortic syndrome and elevated inflammatory markers. The treatment consists of antibiotic therapy (based on blood cultures) in combination with surgical or endovascular approach according to the general condition of the patient. The main complication, depending on the rate of progression, is aortic wall rupture with fatal consequences.
- MeSH
- aneurysma hrudní aorty * diagnostické zobrazování etiologie komplikace patologie terapie MeSH
- aortitida * diagnostické zobrazování etiologie komplikace patologie terapie MeSH
- CT angiografie MeSH
- fatální výsledek MeSH
- lidé MeSH
- nepravé aneurysma diagnostické zobrazování etiologie komplikace patologie terapie MeSH
- pooperační komplikace MeSH
- senioři MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- Publikační typ
- kazuistiky MeSH
