- MeSH
- diferenciální diagnóza MeSH
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- nádory jater * MeSH
- nemoci jater * MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- Publikační typ
- přehledy MeSH
BACKGROUND: Gastrointestinal stromal tumors (GISTs) may arise in any part of the gastrointestinal tract; extra-gastrointestinal locations are extremely rare. Only a few cases of extragastrointestinal stromal tumor arising from the pancreas were reported. None of the reports described a long-term follow-up of the patients. METHOD: This report describes an interesting and unusual case of GIST arising from the pancreas. RESULTS: A 74-year-old female presented with a palpable abdominal mass. CT scan showed a large mass 11 x 8 x 4 cm originating from the tail of the pancreas. Percutaneous biopsy revealed a GIST predominantly with spindle cells, but some parts also contained epitheloid cells. The patient was treated by distal pancreatic resection with splenectomy. Immunohistochemistry of the tumor showed a staining pattern characteristic of GIST. The patient has achieved a long-term survival of five years and six months without any sign of recurrence of the disease. CONCLUSION: This is the first reported case of an extra-gastrointestinal stromal tumor arising from the pancreas treated surgically, with a long-term survival.
- MeSH
- biopsie MeSH
- časové faktory MeSH
- gastrointestinální stromální tumory patologie chirurgie MeSH
- imunohistochemie MeSH
- lidé MeSH
- nádory slinivky břišní patologie chirurgie MeSH
- pankreatektomie MeSH
- počítačová rentgenová tomografie MeSH
- senioři MeSH
- splenektomie MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- MeSH
- adjuvantní chemoterapie metody využití MeSH
- analýza přežití MeSH
- chemoradioterapie metody využití MeSH
- chirurgie trávicího traktu metody využití MeSH
- dávka záření MeSH
- gastroezofageální junkce patologie MeSH
- Kaplanův-Meierův odhad MeSH
- lidé MeSH
- metaanalýza jako téma MeSH
- nádory jícnu farmakoterapie chirurgie radioterapie MeSH
- nádory žaludku farmakoterapie chirurgie radioterapie MeSH
- předoperační péče metody využití MeSH
- retrospektivní studie MeSH
- statistika jako téma MeSH
- výsledky a postupy - zhodnocení (zdravotní péče) MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přednášky MeSH
INTRODUCTION: Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. Authors present a 67-year-old woman treated for iron deficiency anemia for the past 5 years. Suddenly, her disease was presented with painless severe gastrointestinal bleeding (fresh melena). Inverted Meckel's diverticulum with ectopic pancreatic tissue as a source of severe gastrointestinal bleeding was diagnosed by intraoperative enteroscopy. CONCLUSION: A combination of inversion of Meckel's diverticulum with ectopic pancreatic tissue is extremely rare, particularly in elderly patient. Capsule endoscopy, double balloon enteroscopy, and ultimately intraoperative enteroscopy may be helpful in timely diagnosis.
- MeSH
- choristom komplikace patologie MeSH
- gastrointestinální endoskopie metody MeSH
- gastrointestinální krvácení diagnóza etiologie patologie chirurgie MeSH
- hodnocení rizik MeSH
- imunohistochemie MeSH
- jehlová biopsie MeSH
- kapslová endoskopie metody MeSH
- krevní transfuze MeSH
- lidé MeSH
- Meckelův divertikl komplikace diagnóza MeSH
- následné studie MeSH
- nemoci ilea diagnóza chirurgie MeSH
- pankreas MeSH
- senioři MeSH
- výsledek terapie MeSH
- vzácné nemoci MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- práce podpořená grantem MeSH
The major postoperative complication after open and laparoscopic distal pancreatectomy is pancreatic fistula. Different operative techniques have been tested to minimize this unpleasant complication. We evaluated a new technique for pancreatic stump reinforcement with synthetic glue after laparoscopic distal pancreatectomy. Ten female domestic pigs were divided into 2 groups; in group A (n=5), the pancreas was transected using an EndoGIA stapler, whereas in group B (n=5), the pancreas was transected using a Ligasure device and the pancreatic stump was reinforced with a hydrogel sealant. The clinical postoperative course was uneventful in all the cases. No differences were observed in pancreatic remnant healing between the groups, and only minor microscopic alterations of the healing process were found in the groups. The technique using Ligasure transection reinforced by the hydrogel sealant seems to be comparable with the standard transection technique using the stapler.
- MeSH
- chirurgické staplery MeSH
- hojení ran fyziologie MeSH
- laparoskopie MeSH
- ligace MeSH
- pankreas fyziologie chirurgie MeSH
- pankreatektomie metody MeSH
- PEG-DMA hydrogel terapeutické užití MeSH
- prasata MeSH
- zvířata MeSH
- Check Tag
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare condition characterised by chronic or relapsing moderate ileous episodes resulting from multiple small intestinal strictures, multiple shallow ulcers of the small bowel and favourable therapeutical effect of glucocorticosteroids. The aim of this paper was to evaluate three cases of CMUSE diagnosed within 10 years at a tertiary gastroenterology centre. Three females (35, 50, 60 years) were presented with colicky pain, repeated moderate ileous episodes and weight loss. Multiple fibrous strictures and ulcers of the small bowel were found. All three patients responded to glucocorticosteroid treatment. Tandem tight jejunal stenoses were dilated endoscopically by means of double balloon enteroscopy. In conclusion, CMUSE should always be considered when chronic moderate ileous episodes and multiple small intestinal strictures and ulcers of uncertain aetiology are found. Double balloon enteroscopy enables precise diagnostic work, possible endoscopic treatment of stenoses, may obviate the need for surgery and prevent excessive small bowel resections.
The aim of this project was to develop a methodology to introduce wireless video capsule endoscopy in preclinical research. Five mature female pigs (Sus scrofa domestica) were selected for the study. Capsule endoscopes (the EndoCapsule system; Olympus) were introduced into the duodenum endoscopically in each of the animals. The life span of batteries (i.e., total time of endoscopy recording) was 487-540 min (median 492 min). The capsule endoscope reached the cecum during enteroscopy once (after 7 h 57 min), in the remaining cases, endoscopy recordings terminated in the distal or terminal ileum. All capsule enteroscopies found a normal pattern of the small intestine. The intestinal lumen is narrower, transverse folds are sparse or even absent, villi are wider but less prominent in pigs compared to humans. Capsule endoscopy in experimental pigs will be helpful for future trials on injury of different drugs and xenobiotics to the small bowel.
- MeSH
- gastrointestinální endoskopie metody MeSH
- kapslová endoskopie metody MeSH
- prasata MeSH
- tenké střevo cytologie MeSH
- zvířata MeSH
- Check Tag
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- práce podpořená grantem MeSH
- MeSH
- karcinom MeSH
- lidé MeSH
- metastázy nádorů MeSH
- nádory jater MeSH
- nádory srdce MeSH
- nádory žlučníku MeSH
- senioři MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- kazuistiky MeSH