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MeSH: komplikace těhotenství-dietoterapie

9 záznamů v Medvik Filtry

Kapitola

Nutritional support during pregnancy and breastfeeding

Sobocki, J
Autor Sobocki, J Department of Surgery and Clinical Nutrition, Medical University of Warsaw, Poland
Maňák, Jan
Autor Autorita 3rd Department of Medicine, Metabolic Care and Gerontology Medical Faculty, Charles University, Hradec Králové, Czech Republic
Kunecki, M
Autor Kunecki, M Department of Clinical Nutrition, Department of General and Vascular Surger, M. Pirogow Provincial Specialist Hospital, Lodz, Poland
Dudrick, S. J
Autor Dudrick, S. J Department of Surgery, St. Mary's Hospital, Waterbury Yale University School of Medine, New Haven, USA

Basics in clinical nutrition. 2019 ; () : 565-569.

ISBN 978-80-7492-427-9
Medvik
Zdroj

MeSH
fetální úmrtnost MeSH
hladovění komplikace patofyziologie MeSH
komplikace těhotenství * dietoterapie prevence a kontrola MeSH
laktace fyziologie MeSH
lidé MeSH
nutriční nároky MeSH
nutriční podpora * metody MeSH
nutriční terapie * metody MeSH
parenterální výživa metody MeSH
podvýživa komplikace patofyziologie MeSH
těhotenství MeSH
těhotné ženy MeSH
Check Tag
lidé MeSH
těhotenství MeSH
ženské pohlaví MeSH

Článek

Evolution of reproductive disorders related to celiac disease under gluten-free diet

International journal of celiac disease. 2017 ; 5 (2) : 69-71.

ISSN 2334-3427
Medvik
Zdroj

Introduction: Celiac disease (CD) is an autoimmune enteropathy induced by the ingestion of gluten (wheat, barley, rye). The classical form has become a minority. Currently, the most frequent forms of presentation are extradigestive with various manifestations, among others, reproductive disorders. The aim of our study is to assess the frequency of these disorders in CD and their evolution under gluten-free diet (GFD). Materials and methods: Descriptive retrospective study of 173 patients with CD followed in the department of diseases of the digestive tract "Médecine C" of the Ibn Sina Hospital in Rabat, over a period of 18 years. Result: In 173 patients with CD, 58 patients (28,9%) had reproductive disorders. There are 53 women and 5 men. The average age was 32,25 years. The diagnosis of CD is based on histology and serology. The Reproductive problems were never isolated but always associated with other digestive or extra-digestive signs at the time of diagnosis of CD. These disorders are represented by: delayed puberty in 11 patients (19%), secondary amenorrhea in 13 patients (22.4%), irregular menstrual in 12 patients (20.6%), absence of development of secondary sex characteristics in 8 patients (12.5%), spontaneous abortions in 7 patients (10.9%), menometrorrhagia in 4 patients (13.8%), primary sterility in 5 patients (8.6%), early menopause in 6 patients (10.3%), premature delivery in 3 patients (5%), primary amenorrhea in 2 patients (3.4%) and intrauterine fetal death in one case (1.7%). All our patients have had a GFD. 15 patients lost to follow-up, two patients died and 12 patients undergoing follow-up. The remaining 29 patients, the evolution of reproductive disorders under GFD was favorable in 26 patients (90%), with the normalization of cycles in 15 patients, resumption of cycles in 6 patients, development of secondary sex characteristics in 2 patients, fertility resumption in one case, initiation of cycles after primary amenorrhea in one case and delivery of a newborn at term after premature deliveries in one case. The evolution was unfavorable in 3 patients with the notion of miscarriage 4 years after the start of the GFD in one patient and the absence of cycle resumption in two patients. Conclusion: The reproductive disorders associated with CD are frequent and varied. In our study, these disorders responded very well under a GFD, conducted in 90% of patients. These disorders are thus reversible under this diet.

MeSH
bezlepková dieta MeSH
celiakie * dietoterapie komplikace MeSH
dospělí MeSH
infertilita dietoterapie etiologie MeSH
komplikace těhotenství dietoterapie etiologie MeSH
lidé MeSH
menstruační poruchy dietoterapie etiologie MeSH
Check Tag
dospělí MeSH
lidé MeSH
mužské pohlaví MeSH
ženské pohlaví MeSH
Publikační typ
pozorovací studie MeSH
Geografické názvy
Maroko MeSH

Článek

Celiakie pro praxi
[Celiac disease for practice]

Medicína pro praxi. 2011 ; 8 (9) : 354-359.

Medvik
Zdroj

Celiakie je častá autoimunitní choroba dětí i dospělých ve všech zemích světa. Její prevalence v České republice se odhaduje na 1:200– 1:250. Celiakie je diagnostikována v české populaci nedostatečně často a naopak často pozdě. Příčinou je změněný fenotyp s častými extraintestinálními symptomy u dospělých nemocných. Manifestace celiakie závisí nejen na genetické dispozici, ale také na funkci střevní slizniční bariéry, jejíž propustnost je ovlivněna střevním mikrobiomem a slizničním imunitním systémem. Nediagnostikovaná celiakie je provázena malnutricí, přidruženými autoimunitními chorobami a komplikacemi, z nichž některé mají život ohrožující charakter. Jedinou kauzální terapií je finančně nákladná celoživotní bezlepková dieta, tj. úplné vyloučení všech pokrmů obsahujících obiloviny v jakékoliv formě. Četnost kojení je nepřímo úměrná prevalenci celiakie v populaci. Virové enteritidy v prvním roce života poškozují slizniční bariéru a jsou rizikovým faktorem manifestace celiakie. Metodický pokyn Ministerstva zdravotnictví ČR, „Cílený screening celiakie“, umožňuje vyhledat velkou populaci dosud nediagnostikovaných celiaků a zahájit jejich léčbu bezlepkovou dietou.

Celiac disease is a frequent autoimmune disorder of children and adults with world-wide distribution. The prevalence in Czech Republic amounts to 1:200–1:250. In Czech population celiac disease remains underdiagnosed and frequently diagnosed at a late stage. The reasons include an altered phenotype of the disease with frequent extraintestinal symptoms in adults. The manifestation of celiac disease depends on the genetic disposition as well as on the permeability of the intestinal mucosal barrier modulated by the intestinal microbiome and the mucosal immune system. Undiagnosed celiac disease may be a serious condition due to malnutrition, associated autoimmune conditions and life-threatening complications. The only causal therapy is the life-long gluten-free diet with complete exclusion of all cereals. This regimen is very expensive. Breast-feeding decreases the prevalence of celiac disease. Viral enteritis in the first year of life may damage the mucosal barrier and facilitate the manifestation of celiac disease. The Program of “Targeted Celiac Disease Screening” published by Czech Ministry of Health may enable to reveal the extensive population of undiagnosed celiac subjects and start their therapy with gluten-free diet.