Dvaapadesát pacientů trpících předčasnou ejakulací bylo léčeno intermitentně (tj. pouze v den předpokládaného styku 4–6 h. před aktem podávaným) sertralinem 50 mg/d. Výsledky byly literárně srovnatelné s údaji o sertralinu, ostatních SSRI a klomipraminu, podávanými kontinuálně. Účinnost léčby podle Intravaginal Ejaculatory Latency Time byla 83 % (N = 43), podle kritéria uspokojení partnerky 75 % (N = 39) a podle hodnocení (lékař, pacient nebo oba) v den poslední kontroly 69 % (N = 36). Předčasnou ejakulaci je možné léčebně ovlivňovat intermitentním podáváním sertralinu.
Fifty two patients suffering from premature ejaculation were treated intermitently (i.e. only in the day of the expected intercourse, given 4–6 hours before the act) with sertraline 50 mg/d. The results were comparable to the results of other studies in which setraline, other SSRIs and clomipramine were asministered continually. The treatment efficacy was: 83 % (N = 43) according to the Intravaginal Ejaculatory Latency Time, 75 % (N = 39) according to the female partner‘s satisfaction, 69 % (N = 36) according to the evaluation in the last check-up day (doctor, patient or both). The premature ejaculation can be therapeutically influenced by sertraline given intermitently.
European urology supplements, ISSN 1569-9056 vol. 6, no. 13, July 2007
763-786 s. : il., tab. ; 28 cm
- MeSH
- Ejaculation MeSH
- Interpersonal Relations MeSH
- Psychoanalysis MeSH
- Selective Serotonin Reuptake Inhibitors therapeutic use MeSH
- Sexual Dysfunction, Physiological MeSH
- Sexual Dysfunctions, Psychological MeSH
- Sex Counseling MeSH
- Treatment Outcome MeSH
- Publication type
- Collected Work MeSH
- Conspectus
- Patologie. Klinická medicína
- NML Fields
- andrologie
- sexuologie
Recent findings indicate that men with premature ejaculation report more frequent sexual problems associated with increased anxiety and interpersonal difficulties. Bearing this in mind, the neuroendocrine changes were examined in men with premature ejaculation and compared to other indicators of stressful experiences to see whether there can be any correlation which could indicate how these factors may contribute to the aetiology of premature ejaculation. Our study comprised 60 male outpatients diagnosed as having secondary premature ejaculation. Clinical examinations were focused on biochemical analysis of cortisol and psychometric scoring using a diagnostic tool for premature ejaculation, traumatic stress and somatoform dissociation. The control group consisted of a 60 healthy men. The results showed significant Spearman correlations of the Premature Ejaculation Diagnostic Tool score with Trauma Symptom Checklist score (R = .86), cortisol level (R = .47) and Somatoform Dissociation Questionnaire score (R = .61). In the control group, the results did not reach statistical significance. Spearman correlations of the Premature Ejaculation Diagnostic Tool score with Trauma symptoms checklist score was (R = .21), cortisol (R = .27) and with Somatoform dissociation questionnaire score (R = .25). These results represent the first reported findings documenting the relationship of traumatic stress indicators with the experience of secondary premature ejaculation and cortisol levels.
- MeSH
- Ejaculation MeSH
- Humans MeSH
- Premature Ejaculation * diagnosis epidemiology MeSH
- Surveys and Questionnaires MeSH
- Anxiety MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
The aim of my presentation is to discuss case study of a man who visited my practice and claimed problems in the relationship with his wife. He discovered her contacts with other men on her PC. He kept referring particularly to her infidelity and consequently felt very hurt. Up to that point he was convinced that there were no problems either in their relationship or sex life. Only during the third visit he admitted that he has suffered from EP since the very beginning of his active sex life. Material and methods: A forty two years old men come for a first visit in January 2007, apparently full of tension and depression. Following twenty years lasting relationship which he evaluated as ”nice“, last week he discovered that his wife was chatting with other men on line, she developed an emotional relationship with one of them and was sending around her pornographic images. He claimed that there were no problems in their sex life and that he was always the one who initiated it. In October ’06 she had moved to her own bedroom supposedly due to her back pain. Retrospectively he saw as the main problem in the relationship the lack of communication. During his next visit he rather dealt with the questions of the future of the relationship and asked if he should be giving her one more chance. It was suggested that his wife shall visit the practice too. During the third visit he gradually came to the conclusion that there must be something wrong with him for he ejaculates too early, sometimes already before he enters the vagina, sometimes a few seconds after the beginning of copulation. Along with a continual psychotherapy the treatment by sertralin was applied. Conclusions: With these kind of patients what is most important is exploration and of course a complex examination. This particular patient claimed his merital problems as the first point. Late treatment of his EP may not safe the marriage but certainly can contribute to better communication of the couple. In order to sucessfully resolve this case a cooperation of his wife would be desireable.
Potíže s ejakulací jsou zejména u urologických nemocných poměrně časté a nezřídka vedou ke zhoršení kvality sexuálního života i partnerského soužití. Přesto jsou často opomíjené. Bohužel ne vždy jsou ovlivnitelné. Muže je třeba náležitě poučit o možných negativních vlivech urologické medikace i operačních výkonů na ejakulaci. Následující text se zaměřuje na anejakulaci, retrográdní ejakulaci, opožděnou ejakulaci a bolestivou ejakulaci.
Difficulties with ejaculation are particularly common among urological patients and often lead to deterioration in quality of sexual life and partnership. Yet are often not disussed. Unfortunatelly, not always are influenceable. Patients should be properly informed about possible negative effects of urological medication or surgical procedures on ejaculation. The following text focuses on anejaculation, retrograde ejaculation, delayed ejaculation and painful ejaculation.
Delayed ejaculation belongs to the group of sexual disorders in men. The causes of delayed ejaculation or anejaculation are not exactly known. It is assumed that it can be caused by psychogenic or organic influences or their combinations. One of the causes of delayed ejaculation may be elevated prolactin levels, which may be increased by psychosocial stress, pituitary disorders or also treatment with selective serotonin reuptake inhibitors in the treatment of depression. We tested a selected group of 50 men who were diagnosed with a depressive disorder and whose antidepressant treatment lasted for at least 24 weeks. These patients reported long-term delayed ejaculation or, in some cases, anejaculation as comorbidity. The results showed significant Spearman's correlation between elevated prolactin levels and intravaginal ejaculation latency values (R = 0.45), as well as between Beck's Depression-II inventory and intravaginal ejaculation latency and latency values (R = 0.48).
- MeSH
- Depressive Disorder * MeSH
- Ejaculation MeSH
- Humans MeSH
- Premature Ejaculation * etiology MeSH
- Prolactin MeSH
- Selective Serotonin Reuptake Inhibitors pharmacology therapeutic use MeSH
- Sexual Dysfunction, Physiological * etiology MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
Autoři v článku shrnují aktuální pohled na problematiku předčasné ejakulace, která společně s erektilní dysfunkcí patří mezi nejčastější mužské sexuální dysfunkce. Důraz je kladen na farmakoterapeutické možnosti v každodenní klinické praxi.
The authors summarize the current knowledge of premature ejaculation which is together with erectile dysfunction one of the most common male sexual dysfunctions. The role of pharmacotherapy in everyday clinical practice has been emphasized.
- Keywords
- IELT,
- MeSH
- Anesthetics, Local therapeutic use MeSH
- Benzylamines MeSH
- Diagnosis, Differential MeSH
- Ejaculation * physiology drug effects MeSH
- Clomipramine administration & dosage adverse effects MeSH
- Humans MeSH
- Naphthalenes MeSH
- Premature Ejaculation * diagnosis pathology therapy MeSH
- Psychotherapy MeSH
- Psychotropic Drugs adverse effects therapeutic use MeSH
- Selective Serotonin Reuptake Inhibitors administration & dosage adverse effects therapeutic use MeSH
- Serotonin physiology MeSH
- Sexual Health MeSH
- Check Tag
- Humans MeSH
- Male MeSH
