Reaching to target locations on the body has been studied little despite its importance for adaptive behaviors such as feeding, grooming, and indicating a source of discomfort. This behavior requires multisensory integration given that it involves coordination of touch, proprioception, and sometimes vision as well as action. Here we examined the origins of this skill by investigating how infants begin to localize targets on the body and the motor strategies by which they do so. Infants (7-21 months of age) were prompted to reach to a vibrating target placed at five arm/hand locations (elbow, crook of elbow, forearm, palm, and top of hand) one by one. To manually localize the target, infants needed to reach with one arm to the other. Results suggest that coordination increases with age in the strategies that infants used to localize body targets. Most infants showed bimanual coordination and usually moved the target arm toward the reaching arm to assist reaching. Furthermore, intersensory coordination increased with age. Simultaneous movements of the two arms increased with age, as did coordination between vision and reaching. The results provide new information about the development of multisensory integration during tactile localization and how such integration is linked to action.
- MeSH
- Touch physiology MeSH
- Touch Perception physiology MeSH
- Infant MeSH
- Humans MeSH
- Movement physiology MeSH
- Proprioception physiology MeSH
- Psychomotor Performance physiology MeSH
- Child Development physiology MeSH
- Check Tag
- Infant MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- MeSH
- Humans MeSH
- Birth Injuries MeSH
- Premature Birth MeSH
- Medical Audit MeSH
- Pregnancy MeSH
- Delivery, Obstetric methods MeSH
- Pregnancy Outcome MeSH
- Check Tag
- Humans MeSH
- Pregnancy MeSH
- Female MeSH
- Geographicals
- United Kingdom MeSH
40 s. : il.
Autoři uvádějí přehled současných poznatků o roli volných radikálů a antioxidantů v patogeneze a terapii plicních onemocnění, jmenovitě u cystické fibrozy, zánětů plic, hyperoxického postižení plic novorozenců, syndromu dechové tísně dospělých, bronchiálního astmatu a poškození pUc znečištěným vzduchem v okolí. Kouření cigaret je spojeno s příjmem velkého kvanta volných radikálů, kuřáci mívají nižší antioxidační kapacitu séra a snížené hladiny vitaminu C, E a redukovaného glutathionu, které se na inaktivaci volných radikálů podílejí. Při kouření vzniká oxidační stres a vazokonstrikcie plicních cév. Ihnalace volných radikálů způsobuje m. j. i inaktivaci antiproteáz a prispívá ke vzniku plicní rozedrny. Podávání antioxidantů spolu s antiflogistiky se může uplatnit v terapii plicních onemocnění.
The authors summarized actual informations concerning the role of free radicals and antioxidants in the pathogenesis and therapy of pulmonary disease, namely in cystic fibrosis, pneumonias, hyperoxic lung injury of newborns, ARDS, bronchials asthma and pulmonary damage by environmental air pollution. Cigarette smokers usually have decreased antioxidative serum capacity as well levels of vitamin C, E and reduced glutathione, those substances take in free radicals inactivation. Smoking induces oxidative stress and pulmonary vasoconstriction. Inhalation of free radicals leed to antiproteinases inactivation and contributes to development of pulmonary emphysema. Therapeutic application of antioxidants, together wiih antiphlogistics can be effective in pulmonary diseases treatment.
British journal of psychiatry, ISSN 0007-1250 Supplement Vol. 159. 14
112 s. : obr., tab., přeruš.bibliogr.
427 s. : obr., tab.
Elsevier monographs ; 15. Biosciences section. Biochemical subseries
71 stran : ilustrace ; 19 cm
- MeSH
- Hemoglobins MeSH
- Publication type
- Congress MeSH
- Collected Work MeSH
- News MeSH
- Conspectus
- Biochemie. Molekulární biologie. Biofyzika
- NML Fields
- biochemie
Reproduction, ISSN 0954-0725 abstract series no. 28, July 2002
35 s. ; 30 cm
- MeSH
- Reproductive Techniques, Assisted MeSH
- Fertility MeSH
- Fertilization MeSH
- Infertility MeSH
- Reproductive Control Agents MeSH
- Reproductive Medicine MeSH
- Reproductive Techniques MeSH
- Publication type
- Meeting Abstract MeSH
- Conspectus
- Fyziologie člověka a srovnávací fyziologie
- NML Fields
- reprodukční lékařství
British journal of cancer, ISSN 0007-0920 vol. 85, suppl. 1, July 2001
116 s. ; 30 cm
British journal of pharmacology. November, ISSN 0007-1188 Supplement vol. 128
225P-312P s. ; 32 cm