PURPOSE: The International Study of Movement Behaviors in the Early Years (SUNRISE) was conducted in Tunisia to assess the proportion of preschoolers who met the World Health Organization guidelines for physical activity, sedentary behavior, and sleep. The study also evaluated the feasibility of the methods for the SUNRISE study. METHODS: Five kindergartens were recruited from urban and rural areas in Tunisia. Physical activity and sleep duration were assessed using a waist-worn ActiGraph. Screen time and sleep quality were assessed via an interview-administered parent questionnaire. The NIH Toolbox was used. RESULTS: A total of 112 preschoolers were assessed (50 boys, age = 4.1 [0.58]). Only 18% of children met all recommendations of the World Health Organization guidelines, while 53% met the sedentary screen time (in minutes per day), and 41% met physical activity recommendation (in minutes per day). Eighty-one percent of children met the sleep duration recommendation (in minutes per day). There was good compliance with the ActiGraph protocol. CONCLUSIONS: This pilot study provided important insights into the feasibility of the study and the movement behaviors of Tunisian preschool children. The results suggest there is a need to promote healthy levels of physical activity and sedentary screen time in children, which should be a priority in public health initiatives, including preschool curricula, in Tunisia.

• MeSH
• Actigraphy MeSH
• Screen Time MeSH
• Exercise * MeSH
• Humans MeSH
• Pilot Projects MeSH
• Child, Preschool MeSH
• Surveys and Questionnaires MeSH
• Sedentary Behavior * MeSH
• Sleep * MeSH
• Feasibility Studies MeSH
• Check Tag
• Humans MeSH
• Male MeSH
• Child, Preschool MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Tunisia MeSH

BACKGROUND: Processes shaping the formation of the present-day population structure in highly urbanized Northern Europe are still poorly understood. Gaps remain in our understanding of when and how currently observable regional differences emerged and what impact city growth, migration, and disease pandemics during and after the Middle Ages had on these processes. RESULTS: We perform low-coverage sequencing of the genomes of 338 individuals spanning the eighth to the eighteenth centuries in the city of Sint-Truiden in Flanders, in the northern part of Belgium. The early/high medieval Sint-Truiden population was more heterogeneous, having received migrants from Scotland or Ireland, and displayed less genetic relatedness than observed today between individuals in present-day Flanders. We find differences in gene variants associated with high vitamin D blood levels between individuals with Gaulish or Germanic ancestry. Although we find evidence of a Yersinia pestis infection in 5 of the 58 late medieval burials, we were unable to detect a major population-scale impact of the second plague pandemic on genetic diversity or on the elevated differentiation of immunity genes. CONCLUSIONS: This study reveals that the genetic homogenization process in a medieval city population in the Low Countries was protracted for centuries. Over time, the Sint-Truiden population became more similar to the current population of the surrounding Limburg province, likely as a result of reduced long-distance migration after the high medieval period, and the continuous process of local admixture of Germanic and Gaulish ancestries which formed the genetic cline observable today in the Low Countries.

• MeSH
• History, Medieval MeSH
• Genetic Variation MeSH
• Genome, Human MeSH
• Genomics MeSH
• Humans MeSH
• Plague epidemiology   history   genetics   MeSH
• Genetics, Population MeSH
• Urbanization * history   MeSH
• Check Tag
• History, Medieval MeSH
• Humans MeSH
• Publication type
• Journal Article MeSH
• Historical Article MeSH
• Geographicals
• Belgium MeSH

Cíl: Cílem longitudinální studie bude zjistit rozdíly v 24hodinovém pohybovém chování (24hMB) (tj. spánku, sedavém chování (SB) a pohybové aktivitě (PA)) u českých dětí po jejich přestupu z mateřské do základní školy (ZŠ) (resp. z první/druhé třídy ZŠ do vyšších ročníků ZŠ) s ohledem na socioekonomické zázemí rodin, výskyt nadměrné tělesné hmotnosti účastníků či účasti v organizované PA. Metodika: 24hMB bude monitorováno po dobu 7 dnů pomocí akcelerometrů ActiGraph u rodin z městských a venkovských obcí z regionů Čech, Moravy a Slezska, jejichž členové dokončili první etapu výzkumu v období března 2022 až května 2023. Celkem 260 rodin, které dokončily první etapu výzkumu, poskytlo v rodinném deníku kontaktní údaje a nevyloučilo možnost pokračovat ve výzkumu ve druhé etapě v roce 2025/2026. Rodinný deník bude kromě informací o každodenním času uléhání/vstávání, době trávené před obrazovkou/monitorem/displejem obsahovat i informace o účasti v organizované PA, antropometrická data a údaje o rodinném zázemí. Výsledky: Z první etapy výzkumu vyplynulo, že celkem 25,9 % dívek a 26,7 % chlapců splnilo všechna tři doporučení ke spánku, PA a SB současně a dalších 44,7 % dívek a 46,1 % chlapců dosáhlo alespoň kombinaci dvou z těchto tří doporučení, bez rozdílů mezi pohlavím, věkovou kategorií nebo úrovní tělesné hmotnosti dětí. Nadměrná tělesná hmotnost matek významně (p < 0,05) snížila šanci dětí dosáhnout alespoň dvou ze tří doporučení, zatímco vysokoškolské vzdělání rodičů a dodržování alespoň dvou ze tří doporučení matkami významně (p < 0,05) zvýšilo pravděpodobnost, že také děti doporučení dodrží. Účast dětí v organizované PA významně (p < 0,05) zvyšuje jejich šanci na dosažení alespoň dvou ze tří doporučení k 24hMB. Závěry: První etapa longitudinálního výzkumu poukázala na stěžejní rodinné faktory (úroveň vzdělání rodičů, matčina úroveň tělesné hmotnosti a míra dosažení doporučení k 24hMB, podpora aktivní účasti dětí v organizované PA) zvyšující šanci dětí ke splnění zdravotních doporučení pro 24hMB.

Objective: The aim of this longitudinal study will be to investigate the differences in 24-hour movement behaviour (24hMB) (i.e., sleep, sedentary behaviour (SB) and physical activity (PA)) in Czech children after their transition from kindergarten to primary school (or from first/second grade to upper grades of primary school) with respect to the socioeconomic background of families, the prevalence of overweight participants or participation in organised PA. Methods: 24hMB will be monitored for seven days using ActiGraph accelerometers in families from urban and rural areas in the Bohemia, Moravia and Silesia regions, whose members completed the first phase of the study between March 2022 and May 2023. The 260 families who finished the first phase of the research provided their contact details in the family diary and have not ruled out the possibility of participating in the second phase in 2025/2026. The family diary will include information on daily bedtime and wake-up times, screen time, and participation in organised PA, as well as anthropometric data and family background information. Results: The findings from the first phase of the research showed that a total of 25.9% of girls and 26.7% of boys met all three guidelines on sleep, PA and SB simultaneously, and 44.7% of girls and 46.1% of boys achieved at least a combination of two of the three guidelines. No differences were observed between gender, age, or body weight levels of the children. Maternal excess body weight significantly (p < 0.05) decreased the odds of children achieving at least two of the three guidelines, whereas parental higher education and maternal adherence to at least two of the three guidelines significantly (p < 0.05) increased the odds that children also complied with the guidelines. Children’s participation in organised PA significantly (p < 0.05) increased their chances of achieving at least two of the three 24hMB guidelines. Conclusions: The first phase of the longitudinal research highlighted key family factors (parental education level, mother’s body weight, adherence to 24hMB guidelines, and support for children’s active participation in organised PA) that increase children’s chances of meeting guidelines for 24hMB.

• Keywords
• studie FAMIPASS,
• MeSH
• Accelerometry MeSH
• Child MeSH
• Humans MeSH
• Longitudinal Studies MeSH
• Adolescent MeSH
• Motor Activity * MeSH
• Child, Preschool MeSH
• Sedentary Behavior * MeSH
• Sleep MeSH
• Parent-Child Relations MeSH
• Check Tag
• Child MeSH
• Humans MeSH
• Adolescent MeSH
• Male MeSH
• Child, Preschool MeSH
• Female MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH
• Geographicals
• Czech Republic MeSH

Human movement behaviour typically unfolds in 24-h cycles, with children being additionally influenced by their parents. Therefore, the aim of this study was to investigate the adherence of 3-10-year-old children to the World Health Organization's (WHO) 24-h movement behaviour guidelines in relation to the behaviours of their mothers/fathers. Data from the Czech cross-sectional FAMIly Physical Activity, Sedentary behaviour and Sleep study included 381 families (with at least one child aged 3-10 years) from urban and rural areas across all three regions of Czechia. Twenty four-hour movement behaviour (sleep, sedentary behaviour, and physical activity) was monitored using ActiGraph accelerometers placed on the non-dominant wrists of children and their parents for seven consecutive days. Children's adherence to the WHO guidelines was analysed using logistic regression analysis. 25.9% of girls and 26.7% of boys simultaneously met all three 24-h movement behaviour guidelines (sleep + sedentary + physical activity), and 44.7% of girls and 46.1% of boys met any combination of two of the three guidelines, regardless of the children's gender, weight, or calendar age. Maternal overweight/obesity significantly (P = .05) decreased the odds of children achieving at least two of the three guidelines, while parental university education and maternal adherence to at least two of the three guidelines significantly (P = .05) increased the odds of children complying with these guidelines. Parents, especially mothers, play an important role in influencing their children in meeting 24-h movement behaviour guidelines and in shaping a healthy lifestyle.

• MeSH
• Exercise * MeSH
• Child MeSH
• Guideline Adherence * statistics & numerical data   MeSH
• Adult MeSH
• Humans MeSH
• Mothers MeSH
• Child, Preschool MeSH
• Cross-Sectional Studies MeSH
• Parents * psychology   MeSH
• Sedentary Behavior * MeSH
• Sleep * MeSH
• Check Tag
• Child MeSH
• Adult MeSH
• Humans MeSH
• Male MeSH
• Child, Preschool MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Czech Republic MeSH

Sborník příspěvků z kolokvia, které se zaměřilo na dějiny epidemií v městech v Českých zemích ve středověku a novověku. Určeno odborné veřejnosti.; Jedenáctý svazek řady Documenta Pragensia Supplementa zahrnuje příspěvky z kolokvia, který pod názvem totožným s titulkem organizoval Archiv hl. města Prahy.Sborník obsahuje pestrou paletu příspěvků od historiků, archivářů, památkářů, etnografky, archeologů a paleopatologa. Prahy se týká mj. stať o počátcích očkování proti neštovicím nebo stať o morovém sloupu v pražské zoo.

• MeSH
• History, 17th Century MeSH
• History, 18th Century MeSH
• History, 19th Century MeSH
• History of Medicine MeSH
• History, Early Modern 1451-1600 MeSH
• History, Medieval MeSH
• Epidemics history   MeSH
• Urban Population history   MeSH
• Cities history   epidemiology   MeSH
• Urban Health history   MeSH
• Check Tag
• History, 17th Century MeSH
• History, 18th Century MeSH
• History, 19th Century MeSH
• History, Medieval MeSH
• Publication type
• Congress MeSH
• Collected Work MeSH
• News MeSH
• Geographicals
• Czech Republic MeSH
• Austria-Hungary MeSH
• Holy Roman Empire MeSH
• Cities history   epidemiology   MeSH

• Conspectus
• Patologie. Klinická medicína
• NML Fields
• epidemiologie
• humanitní vědy a umění

Cíl: Cílem studie je zjistit, zda existují rozdíly v 24hodinovém pohybovém chování, tj. spánku, sedavém chování (SB) a pohybové aktivitě (PA), u 3–8letých dívek a chlapců z rodin s odlišným socioekonomickým zázemím. Metodika: 24hodinové pohybové chování bylo kontinuálně monitorováno po dobu 7 dnů prostřednictvím akcelerometrů u rodin s 3–8letými dětmi z městských a venkovských obcí z regionů Čech, Moravy a Slezska. Socioekonomický status rodin (SES) byl zjišťován pomocí Škály rodinného blahobytu vyplňované rodiči na konci monitorování. Finálně analyzovaný soubor tvoří reprezentativní vzorek 363 rodin s dostupnými daty o 24hodinovém pohybovém chování a SES. Analýza rozptylu byla použitá pro identifikování rozdílů v pohybovém chování dětí s ohledem na jejich pohlaví a SES. Výsledky: Celková doba spánku (resp. hlubokého spánku), jako nejdelší složka z 24hodinového chování, trvala u dětí v rozmezí 9,05–9,32 (resp. 7,51–7,83) hodin denně bez statisticky významných rozdílů mezi dívkami a chlapci nebo dětmi s odlišným SES. V délce trvání každodenního SB (7,63–8,33 hodin), celkové PA (6,61–7,05 hodin) ani PA střední až vysoké intenzity (70–82 minut) nebyl nalezen statisticky významný rozdíl mezi dívkami a chlapci či dětmi s nízkým, středním a vysokým SES. Závěr: Socioekonomický status rodin ani pohlaví dítěte nejsou zdroji rozdílu v délce trvání celkového ani hlubokého spánku, SB či celkové PA 3–8letých dívek a chlapců z rodin s odlišným socioekonomickým zázemím.

Objective: The aim of this study is to investigate whether there are differences in 24-hour physical behaviours, i.e., sleep, sedentary behaviours (SB), and physical activity (PA), in 3–8-year-old girls and boys from families with different socioeconomic backgrounds. Methods: 24-hour movement behaviour was continuously monitored for seven days using accelerometers in families with 3–8-year-old children from urban and rural areas from the regions of Bohemia, Moravia and Silesia. Socioeconomic status (SES) of families was measured using the Family Affluence Scale completed by parents at the end of the monitoring. The final analysis set is a representative sample of 363 families with available data on 24-hour movement behaviour and SES. Analysis of variance was used to identify differences in children’s movement behaviour with respect to their gender and SES. Results: Total sleep time (or deep sleep), as the longest component of the 24-hour behavioural time, ranged from 9.05–9.32 (or 7.51–7.83) hours per day for children with no statistically significant differences between girls and boys or children with different SES. There was no statistically significant difference in the duration of daily SB (7.63–8.33 hours), total PA (6.61–7.05 hours) or moderate to high intensity PA (70–82 minutes) between girls and boys or children with low, moderate, and high SES. Conclusion: Neither the socioeconomic status of families nor the gender of the child are the sources of differences in the duration of total or deep sleep, SB or total PA of 3–8-year-old girls and boys from families with different socioeconomic backgrounds.

• MeSH
• Accelerometry methods   instrumentation   MeSH
• Child MeSH
• Humans MeSH
• Motor Activity * MeSH
• Observation MeSH
• Child, Preschool MeSH
• Surveys and Questionnaires MeSH
• Sedentary Behavior MeSH
• Socioeconomic Factors * MeSH
• Sleep MeSH
• Statistics as Topic MeSH
• Check Tag
• Child MeSH
• Humans MeSH
• Child, Preschool MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH

OBJECTIVE: To examine the associations between characteristics of daily rainfall (intensity, duration, and frequency) and all cause, cardiovascular, and respiratory mortality. DESIGN: Two stage time series analysis. SETTING: 645 locations across 34 countries or regions. POPULATION: Daily mortality data, comprising a total of 109 954 744 all cause, 31 164 161 cardiovascular, and 11 817 278 respiratory deaths from 1980 to 2020. MAIN OUTCOME MEASURE: Association between daily mortality and rainfall events with return periods (the expected average time between occurrences of an extreme event of a certain magnitude) of one year, two years, and five years, with a 14 day lag period. A continuous relative intensity index was used to generate intensity-response curves to estimate mortality risks at a global scale. RESULTS: During the study period, a total of 50 913 rainfall events with a one year return period, 8362 events with a two year return period, and 3301 events with a five year return period were identified. A day of extreme rainfall with a five year return period was significantly associated with increased daily all cause, cardiovascular, and respiratory mortality, with cumulative relative risks across 0-14 lag days of 1.08 (95% confidence interval 1.05 to 1.11), 1.05 (1.02 to 1.08), and 1.29 (1.19 to 1.39), respectively. Rainfall events with a two year return period were associated with respiratory mortality only, whereas no significant associations were found for events with a one year return period. Non-linear analysis revealed protective effects (relative risk <1) with moderate-heavy rainfall events, shifting to adverse effects (relative risk >1) with extreme intensities. Additionally, mortality risks from extreme rainfall events appeared to be modified by climate type, baseline variability in rainfall, and vegetation coverage, whereas the moderating effects of population density and income level were not significant. Locations with lower variability of baseline rainfall or scarce vegetation coverage showed higher risks. CONCLUSION: Daily rainfall intensity is associated with varying health effects, with extreme events linked to an increasing relative risk for all cause, cardiovascular, and respiratory mortality. The observed associations varied with local climate and urban infrastructure.

• MeSH
• Time Factors MeSH
• Global Health statistics & numerical data   MeSH
• Rain * MeSH
• Cardiovascular Diseases * mortality   MeSH
• Humans MeSH
• Mortality trends   MeSH
• Respiratory Tract Diseases * mortality   MeSH
• Cause of Death trends   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH

There is no multi-country/multi-language study testing a-priori multivariable associations between non-modifiable/modifiable factors and validated wellbeing/multidimensional mental health outcomes before/during the COVID-19 pandemic. Moreover, studies during COVID-19 pandemic generally do not report on representative/weighted non-probability samples. The Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) is a multi-country/multi-language survey conducting multivariable/LASSO-regularized regression models and network analyses to identify modifiable/non-modifiable factors associated with wellbeing (WHO-5)/composite psychopathology (P-score) change. It enrolled general population-representative/weighted-non-probability samples (26/04/2020-19/06/2022). Participants included 121,066 adults (age=42±15.9 years, females=64 %, representative sample=29 %) WHO-5/P-score worsened (SMD=0.53/SMD=0.74), especially initially during the pandemic. We identified 15 modifiable/nine non-modifiable risk and 13 modifiable/three non-modifiable protective factors for WHO-5, 16 modifiable/11 non-modifiable risk and 10 modifiable/six non-modifiable protective factors for P-score. The 12 shared risk/protective factors with highest centrality (network-analysis) were, for non-modifiable factors, country income, ethnicity, age, gender, education, mental disorder history, COVID-19-related restrictions, urbanicity, physical disorder history, household room numbers and green space, and socioeconomic status. For modifiable factors, we identified medications, learning, internet, pet-ownership, working and religion as coping strategies, plus pre-pandemic levels of stress, fear, TV, social media or reading time, and COVID-19 information. In multivariable models, for WHO-5, additional non-modifiable factors with |B|>1 were income loss, COVID-19 deaths. For modifiable factors we identified pre-pandemic levels of social functioning, hobbies, frustration and loneliness, and social interactions as coping strategy. For P-scores, additional non-modifiable/modifiable factors were income loss, pre-pandemic infection fear, and social interactions as coping strategy. COH-FIT identified vulnerable sub-populations and actionable individual/environmental factors to protect well-being/mental health during crisis times. Results inform public health policies, and clinical practice.

• MeSH
• COVID-19 * epidemiology   psychology   prevention & control   MeSH
• Adult MeSH
• Mental Health * MeSH
• Middle Aged MeSH
• Humans MeSH
• Young Adult MeSH
• Multivariate Analysis MeSH
• Protective Factors * MeSH
• Pandemics MeSH
• Risk Factors MeSH
• Aged MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Young Adult MeSH
• Male MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH

Persons living in industrial environments are exposed to levels of air pollution that can affect their health and fertility. The Czech capital city, Prague, and the Ostrava industrial agglomeration differ in their major sources of air pollution. In Prague, heavy traffic produces high levels of nitrogen oxides throughout the year. In the Ostrava region, an iron industry and local heating are sources of particulate matter (PM) and benzo[a]pyrene (B[a]P), especially in the winter. We evaluated the effects of air pollution on human sperm mitochondrial DNA (mtDNA). Using real-time PCR, we analysed sperm mtDNA copy number and deletion rate in Prague city policemen in two seasons (spring and autumn) and compared the results with those from Ostrava. In Prague, the sperm mtDNA deletion rate was significantly higher in autumn than in spring, which is the opposite of the results from Ostrava. The sperm mtDNA copy number did not show any seasonal differences in either of the cities; it was correlated negatively with sperm concentration, motility, and viability, and with sperm chromatin integrity (assessed with the Sperm Chromatin Structure Assay). The comparison between the two cities showed that the sperm mtDNA deletion rate in spring and the sperm mtDNA copy number in autumn were significantly lower in Prague vs. Ostrava. Our study supports the hypothesis that sperm mtDNA deletion rate is affected by the composition of air pollution. Sperm mtDNA abundance is closely associated with chromatin damage and standard semen characteristics.

• MeSH
• Adult MeSH
• Air Pollutants toxicity   adverse effects   MeSH
• Humans MeSH
• DNA, Mitochondrial * genetics   MeSH
• Sperm Motility drug effects   MeSH
• Particulate Matter toxicity   adverse effects   MeSH
• Police MeSH
• Seasons MeSH
• Spermatozoa * drug effects   MeSH
• DNA Copy Number Variations * MeSH
• Air Pollution * adverse effects   MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Male MeSH
• Publication type
• Journal Article MeSH
• Comparative Study MeSH
• Geographicals
• Czech Republic MeSH

OBJECTIVES: To determine how social factors influence career decisions of dental service providers, particularly focusing on examining the impact of dentists' origins. METHODS: Online survey of Hessian panel dentists, with pairwise comparisons to a set of factors impacting their decision-making process. An Analytic Hierarchy Process examined the weighting of influencing drivers in career choice. RESULTS: Dentists from rural backgrounds were more likely to establish practices in rural areas than those from urban origins. Origin correlated with entrepreneurial intentions and a strong association of rural origin. Dentists who grew up in rural areas were 4.19 times more likely to start a business. CONCLUSION: These findings may support efficient resource allocation and support for rural dental businesses.

• MeSH
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Small Business MeSH
• Professional Practice Location MeSH
• Surveys and Questionnaires MeSH
• Rural Population MeSH
• Career Choice * MeSH
• Rural Health Services MeSH
• Dentists statistics & numerical data   psychology   MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Germany MeSH