• MeSH
• BCG Vaccine MeSH
• Guinea Pigs MeSH
• Vaccination MeSH
• Tuberculosis Vaccines MeSH
• Check Tag
• Guinea Pigs MeSH
• Publication type
• Comparative Study MeSH

• MeSH
• Cytotoxicity Tests, Immunologic MeSH

• MeSH
• Genetics, Microbial MeSH
• Orthomyxoviridae MeSH
• Antibody Formation MeSH

• MeSH
• Arboviruses immunology   pathogenicity   MeSH
• Mice MeSH
• Antibodies, Viral MeSH
• Virulence MeSH
• Check Tag
• Mice MeSH

• MeSH
• Encephalitis, Viral etiology   transmission   prevention & control   MeSH
• Immunogenicity, Vaccine MeSH
• Henipavirus Infections * diagnosis   etiology   prevention & control   MeSH
• Humans MeSH
• Viral Vaccines MeSH
• Nipah Virus * pathogenicity   growth & development   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH

• MeSH
• Hepatitis therapy   MeSH
• Immunotherapy MeSH
• Interferon-alpha therapeutic use   immunology   MeSH
• Neoplasms therapy   MeSH
• Publication type
• Congress MeSH
• Collected Work MeSH

• Conspectus
• Patologie. Klinická medicína
• NML Fields
• alergologie a imunologie
• infekční lékařství
• onkologie

Autori sa v prehľadovej práci venujú problematike očkovania, a to so špecifickým fókusom na moduláciu imunogenity (imunogenicity) vakcín pomocou špecifických bakteriálnych kmeňov. Práve mikrobióm človeka a možnosti jeho ovplyvnenia (vrátane podávania probiotík) sú v posledných rokoch predmetom čoraz intenzívnejšieho skúmania, ako aj viaceré dôležité poznatky o vzájomnej interakcii mikrobiómu, či jeho jednotlivých súčastí so súčasťami imunitného systému. Poukazujeme na nové informácie, ktoré sa zatiaľ, v tejto pomerne zložitej problematike vzájomných interakcií viacerých prostredí a systémov, exaktne získali. S pomocou najmodernejších technológií bude žiaduca charakteristika a úlohy mikrobiómu očkovaných jedincov s cieľom porozumieť napríklad tomu, do akej miery môže osídlenie čreva ovplyvniť imunogenitu vakcín.

This synopsis is devoted to the issue of vaccination with specific focus on modulation of immunogenicity of vaccines with specific bacterial strains. Human microbiome and possibilities of its influencing (including administration of probiotics), became the subject of intensive scientific research in the recent years. Several important findings about mutual interaction of microbiome, its singular components with components of immune system are the results of this investigation. We advert new information that were exactly obtained about this complicated issue of bilateral interactions of several environments and systems. With help of the latest technologies it is going to be necessary to discover characteristics and role of microbiome of the vaccinated individuals with aim to understand for instance the extent of influence of intestinal colonization on immunogenicity of vaccines.

• MeSH
• Adjuvants, Immunologic therapeutic use   MeSH
• Immunogenicity, Vaccine immunology   MeSH
• Humans MeSH
• Probiotics pharmacology   metabolism   MeSH
• Gastrointestinal Microbiome immunology   drug effects   MeSH
• Drug Synergism MeSH
• Antibody Formation immunology   MeSH
• Vaccines immunology   MeSH
• Drug Administration Routes MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

• MeSH
• Interferon Type I pharmacology   immunology   standards   MeSH
• Protein Conformation immunology   MeSH
• Hemic and Lymphatic Diseases therapy   MeSH
• Humans MeSH
• Treatment Failure MeSH
• Antibody Formation MeSH
• Hepatitis, Viral, Human therapy   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

• MeSH
• Cyclophosphamide MeSH
• Leukemia, Experimental immunology   MeSH
• Immunotherapy MeSH
• Mitomycin MeSH
• Mice MeSH
• Check Tag
• Mice MeSH

• MeSH
• Chromatography MeSH
• Antibody Formation MeSH
• Vaccination methods   MeSH
• Influenza Vaccines analysis   MeSH
• Publication type
• Comparative Study MeSH