- Keywords
- aflibercept,
- MeSH
- Anticoagulants contraindications adverse effects MeSH
- Diabetic Retinopathy * diagnosis drug therapy classification therapy MeSH
- Diagnostic Techniques, Ophthalmological MeSH
- Dyslipidemias therapy MeSH
- Hypertension therapy MeSH
- Laser Coagulation methods MeSH
- Humans MeSH
- Ranibizumab pharmacology therapeutic use MeSH
- Receptors, Vascular Endothelial Growth Factor therapeutic use MeSH
- Recombinant Fusion Proteins pharmacology therapeutic use MeSH
- Pregnancy MeSH
- Vitrectomy methods utilization MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Practice Guideline MeSH
- Keywords
- aflibercept,
- MeSH
- Anticoagulants contraindications adverse effects MeSH
- Diabetic Retinopathy * diagnosis drug therapy classification therapy MeSH
- Diagnostic Techniques, Ophthalmological MeSH
- Dyslipidemias therapy MeSH
- Hypertension therapy MeSH
- Laser Coagulation methods MeSH
- Humans MeSH
- Ranibizumab pharmacology therapeutic use MeSH
- Receptors, Vascular Endothelial Growth Factor therapeutic use MeSH
- Recombinant Fusion Proteins pharmacology therapeutic use MeSH
- Pregnancy MeSH
- Vitrectomy methods utilization MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Practice Guideline MeSH
Cíl: Zhodnocení anatomických a funkčních výsledků operace idiopatické makulární díry pomocí 25-gauge pars plana vitrektomie s peelingem vnitřní limitující membrány (MLI) asistované briliantovou modří (BB) a tamponádou expanzivním plynem. Soubor a metodika: Retrospektivní analýza. Do hodnoceného souboru bylo zařazeno 53 očí 52 pacientů (39 žen, 13 mužů) průměrného věku 68,8 roků (58–83), kteří byli na Oftalmologické klinice FNKV operovaní pro idiopatickou makulární díru (stadia II-IV dle Gasse) od 6/2012–7/2014. Všichni pacienti podstoupili 25-gauge pars plana vitrektomii včetně peelingu MLI obarvené briliantovou modří. Jako tamponáda byl použit expanzivní plyn (ve 35 případech 15 % C3F8, v 18 případech 20 % SF6). 50 operací (94,3 %) bylo provedeno v retrobulbární anestezii, 3 operace v anestezii celkové. Po operaci bylo doporučeno udržovat hlavu v pronační poloze 3 dny. Hodnocena byla změna nejlépe korigované zrakové ostrosti (NKZO), nález na optické koherenční tomografii a výskyt komplikací. Výsledky: Průměrná sledovací doba činí 6 měsíců (1–22). Makulární díra byla uzavřena u 49 očí (92,5 %). Průměrná NKZO se zlepšila z 0,16 (0,5–0,05) na 0,5 (1,0–0,1). U 42 očí (79,2 %) se zraková ostrost zlepšila o 3 a více řádků ETDRS optotypů. Závěr: 25-gauge pars plana vitrektomie s peelingem MLI obarvené briliantovou modří a plynovou tamponádou je efektivní a bezpečná metoda léčby idiopatické makulární díry s vysokou pravděpodobností anatomického i funkčního úspěchu. Klíčová slova: makulární díra, 25-gauge, MLI peeling, briliantová modř, plynová tamponáda
25-gauge pars plana vitrectomy with briliant blue assisted internal limiting membrane peeling and gas tamponade for idiopatic macular hole Purpose: The evaluation of anatomic and visual outcomes in idiopatic macular holes treated with 25-gauge pars plana vitrectomy, briliant blue (BB) assisted internal limiting membrane (ILM) peeling and gas tamponade. Materials and methods: Retrospective analysis. 53 eyes of 52 patients (39 women, 13 men) of mean age 68,8 years (58-83) with the diagnosis of stage 2, 3, or 4 macular holes according to Gass Classification from 6/2012 to 7/2014 were included. All patient undergone 25-gauge pars plana vitrectomy with brillinat blue assisted ILM peeling, gas tamponade (35 cases 15 % C3F8, 18 cases 20 % SF6). 50 cases (94,3 %) were performed in retrobulbar anesthesia, 3 cases in general anesthesia. Face-down positioning should have beeen maintained for three days. Best corrected visual acuity (BCVA), optical coherence tomography findings and complications were evaluated. Results: The mean follow-up time was 6 months (1–22). Macular hole closure was achieved in 49 eyes (92,5 %). The mean BCVA improved from 0,16 (0,5–0,05) to 0,5 (1,0–0,1). BCVA was improved by 3 and more ETDRS lines in 42 eyes (79,2 %). Conclusion: 25-gauge pars plana vitrectomy with briliant blue assisted internal limiting membrane peeling and gas tamponade is safe and effective method of macular hole therapy with high anatomic and functional effect. Key words: macular hole, 25-gauge, ILM peeling, brilliant blue, gas tamponade
- MeSH
- Coloring Agents therapeutic use MeSH
- Epiretinal Membrane surgery MeSH
- Middle Aged MeSH
- Humans MeSH
- Ophthalmologic Surgical Procedures methods utilization MeSH
- Tomography, Optical Coherence methods utilization MeSH
- Retinal Perforations * diagnosis surgery physiopathology MeSH
- Postoperative Complications MeSH
- Retrospective Studies MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Severity of Illness Index MeSH
- Vitrectomy * methods utilization MeSH
- Outcome and Process Assessment, Health Care MeSH
- Visual Acuity MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- MeSH
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Retinal Detachment * surgery prevention & control MeSH
- Ophthalmologic Surgical Procedures methods utilization MeSH
- Prospective Studies MeSH
- Retina anatomy & histology surgery pathology MeSH
- Retrospective Studies MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Vitrectomy utilization MeSH
- Outcome and Process Assessment, Health Care MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Aged, 80 and over MeSH
- Aged MeSH
Cieľ práce: Vyhodnotenie efektivity operácií proti odlúpeniu sietnice v závislosti od zmeny spektra primárne indikovaných operácií počas 15 rokov. Materiál a metodika: Do hodnotenia bolo zaradených 1020 očí, 991 pacientov s primárnym regmatogénnym OS, operovaných na Klinike oftalmológie LF UK a UN Bratislava. Do prospektívnej časti, súbor A, z rokov 1999–2001, bolo zaradených 346 očí, 339 pacientov. Do prvej retrospektívnej časti, súbor B, z rokov 1994–1998, bolo zaradených 464 očí, 455 pacientov. Do druhej retrospektívnej časti, súbor C, z rokov 2009–2010, bolo zaradených 210 očí 197 pacientov. Analyzovali sme vstupné oftalmologické nálezy, použitú operačnú terapiu a vyhodnotili sme anatomické a funkčné výsledky. Primárna pars plana vitrektómia bola v súbore A indikovaná v 54,6 %, v súbore B v 27,6 % a v súbore C v 90,4 %. Výsledky: Zlepšenú zrakovú ostrosť po poslednej operácii odlúpenia sietnice sme v súbore A zaznamenali u 54,7 % očí, v súbore B u 58,2 % očí a v súbore C u 57 % očí. Rovnakú zrakovú ostrosť ako pred prvou operáciou pre odlúpenie sietnice malo v súbore A 26,8 %, v súbore B 19,8 % a v súbore C 28% očí. Priloženú sietnicu v súbore A po prvej operácii sme dosiahli v 75 %, po poslednej operácii sa percento úspešnosti zvýšilo na 98 %. V súbore B bola anatomická úspešnosť po prvej operácii 72 % a po poslednej 94 %, v súbore C to bolo po prvej operácii 74 % a po poslednej operácii anatomická úspešnosť vzrástla na 99 %. Záver: Zmena spektra primárne indikovaných operácií pre odlúpenie sietnice za posledných 15 rokov nepriniesla očakávané výrazné funkčné a anatomické zlepšenie. Kľúčové slová: odlúpenie sietnice, chirurgická liečba odlúpenia sietnice, PPV, impresné techniky, pneumatická retinopexia
Purpose: To evaluate the effectiveness of surgery for the rhegmatogenous retinal detachment, depending upon changes in the type of the primary surgery in the last 15 years. Materials and methods: There were 991 patients with primary rhegmatogenous retinal detachment operated (in total 1020 eyes) at the Department of Ophthalmology Faculty of Medicine and University Hospital Bratislava. In the prospective part, in A group concerning the years 1999-2001, there were 346 eyes, 339 patients included. In the first retrospective part, in B group concerning the years 1994-1998 there were 464 eyes, 455 patients. In the second retrospective part, in C group concerning the years 2009-2010, 210 eyes, 197 patients were enrolled. We have analyzed the anatomical and functional results, focusing on the primary indicated surgical procedure of retinal detachment. The primary pars plana vitrectomy was in A group indicated in 54,6%, in group B in 27,6% and in group C in 90,4%. Results: We have recorded the improvement of visual acuity after retinal detachment surgery in A group in 54.7% of eyes, in B group in 58.2% of eyes and in C group in 57% of eyes. The same visual acuity as it was before the first surgery for retinal detachment was recorded in A group in 26.8%, in B group in 19.8% and in C group C in 28% of eyes. Attached retina has been achieved in 75 % in A group after the first surgery and after the last surgical procedure the success rate increased to 98%. The anatomical success was 72% of eyes after the first surgery in B group and after the last surgery it was 94%, in C group the retina was attached in the 74% after primary surgery and 99% after the last surgery. Conclusion: The changing of spectrum indicated by primary retinal detachment surgeries for the last 15 years has not brought the expected major functional and anatomical improvement. Key words: retinal detachment, surgery for retinal detachment, pars plana vitrectomy, pneumatic retinopexy, scleral impresing proceduries
- MeSH
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Retinal Detachment * surgery prevention & control MeSH
- Ophthalmologic Surgical Procedures methods utilization MeSH
- Prospective Studies MeSH
- Retina anatomy & histology surgery pathology MeSH
- Retrospective Studies MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Vitrectomy utilization MeSH
- Outcome and Process Assessment, Health Care MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- MeSH
- Surgical Instruments trends utilization MeSH
- Humans MeSH
- Minimally Invasive Surgical Procedures methods instrumentation trends utilization MeSH
- Ophthalmologic Surgical Procedures * methods instrumentation MeSH
- Postoperative Complications prevention & control MeSH
- Vitrectomy * history methods instrumentation trends utilization MeSH
- Posterior Eye Segment surgery MeSH
- Check Tag
- Humans MeSH
Retinopatia prematúrnych detí (ROP) je potencionálne oslepujúce ochorenie, ktoré postihuje nezrelú sietnicu prematúrnych detí. Autori podávajú súhrnný pohľad indikácií na liečbu ROP a terapeutických možností – štandardnej liečby periférnou abláciou sietnice laserovou koaguláciou a kryopexiou, ako aj použitie off label liečby intravitreálnou aplikáciou anti-VEGF preparátov.
Retinopathy of prematurity (ROP) is a disease that affects immature vasculature in the eyes of premature babies that potentially leads to blindness. Authors describe revised indications for the treatment of ROP, standard treatment – peripheral retinal ablation by laser photocoagulation and the cryotherapy using off label treatment-intravitreal anti-VEGF injection.
- MeSH
- Scleral Buckling utilization MeSH
- Light Coagulation utilization MeSH
- Angiogenesis Inhibitors MeSH
- Cryosurgery MeSH
- Lasers utilization MeSH
- Humans MeSH
- Infant, Premature MeSH
- Infant, Newborn MeSH
- Ophthalmoscopy MeSH
- Retina pathology growth & development MeSH
- Retinopathy of Prematurity * diagnosis classification pathology therapy MeSH
- Vitrectomy utilization MeSH
- Check Tag
- Humans MeSH
- Infant, Newborn MeSH
- Keywords
- pars plana vitrektomie, sklerální plombáž,
- MeSH
- Humans MeSH
- Meta-Analysis as Topic MeSH
- Retinal Detachment * diagnosis etiology surgery pathology therapy MeSH
- Pars Planitis MeSH
- Vitreoretinopathy, Proliferative drug therapy surgery therapy MeSH
- Retina MeSH
- Vitrectomy contraindications methods instrumentation utilization MeSH
- Treatment Outcome MeSH
- Visual Acuity physiology drug effects MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- MeSH
- Diabetes Mellitus, Type 1 MeSH
- Diabetes Mellitus, Type 2 MeSH
- Diabetic Retinopathy history diagnosis epidemiology etiology classification complications physiopathology prevention & control therapy MeSH
- Diagnostic Techniques, Ophthalmological utilization MeSH
- Drug Therapy trends MeSH
- Hyperglycemia blood physiopathology MeSH
- Diabetes Complications prevention & control MeSH
- Laser Coagulation utilization MeSH
- Humans MeSH
- Ophthalmoscopy history utilization MeSH
- Retinal Vessels physiopathology pathology MeSH
- Risk Factors MeSH
- Vitrectomy methods instrumentation trends utilization MeSH
- Check Tag
- Humans MeSH
- MeSH
- Scleral Buckling utilization MeSH
- Light Coagulation utilization MeSH
- Angiogenesis Inhibitors MeSH
- Cryosurgery MeSH
- Lasers utilization MeSH
- Humans MeSH
- Infant, Premature MeSH
- Infant, Newborn MeSH
- Ophthalmoscopy MeSH
- Retina pathology growth & development MeSH
- Retinopathy of Prematurity * diagnosis classification pathology therapy MeSH
- Vitrectomy utilization MeSH
- Check Tag
- Humans MeSH
- Infant, Newborn MeSH
