Lin, Min*
Dotaz
Zobrazit nápovědu
1. vyd. 284 s. : il. ; 18 cm
- MeSH
- fyziognomie MeSH
- jin-jang MeSH
- metafyzické vztahy mezi duší a tělem MeSH
- obličej MeSH
- osobnost MeSH
- výraz obličeje MeSH
- Publikační typ
- populární práce MeSH
- příručky MeSH
- Konspekt
- Okultismus
- NLK Obory
- okultní vědy
- psychologie, klinická psychologie
The primary aim of this study was to investigate the alterations in the microbial community of KK-Ay mice following antibiotic treatment. A comparative analysis of the gut microbiota was conducted between KK-Ay mice treated with antibiotics and those without treatment. The microbial community dynamics in antibiotic-treated KK-Ay mice were meticulously assessed over an eight-week period using 16S rDNA sequencing analysis. Simultaneously, dynamic renal function measurements were performed. The results demonstrated a marked decrease in bacterial DNA abundance following antibiotic intervention, coupled with a substantial reduction in bacterial diversity and a profound alteration in microbial composition. These observed microbiota changes persisted in the KK-Ay mice throughout the eight-week post-antibiotic treatment period. Particularly noteworthy was the reemergence of bacterial populations after two weeks or more, resulting in a microbiota composition resembling that of untreated KK-Ay mice. This transition was characterized by a significant increase in the abundance of clostridia at the class level, Lachnospirales and Oscillospirales at the order level, and Lachnospiraceae, Oscillospiraceae, and Ruminococcaceae at the family level. Concurrently, there was a notable decrease in Clostridia_UCG-014. The observed alterations in the gut microbiota of antibiotic-treated KK-Ay mice suggest a dynamic response to antibiotic intervention and subsequent restoration towards the original untreated state.
- MeSH
- antibakteriální látky * farmakologie aplikace a dávkování MeSH
- Bacteria * klasifikace genetika účinky léků izolace a purifikace MeSH
- biodiverzita MeSH
- DNA bakterií genetika MeSH
- feces mikrobiologie MeSH
- fylogeneze MeSH
- myši MeSH
- ribozomální DNA genetika MeSH
- RNA ribozomální 16S * genetika MeSH
- sekvenční analýza DNA MeSH
- střevní mikroflóra * účinky léků MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
Sustainability of the workforce becomes a crucial issue, of which responsible care for employees can increase job satisfaction and human capital that impact corporate ability to absorb and generate new knowledge. Firms are obligated to provide a healthy and safe working environment for their employees, but it may in turn hinder innovation due to rigid and structured institutional regulations. Drawing on data of 308 China's pharmaceutical firms from 2010 to 2017, we investigated whether employee care can trigger innovation under corporate adoption of the occupational health and safety management system (OHSMS). Our results suggest that both employee care and OHSMS adoption have a positive impact on innovation. Moreover, the positive relationship between employee care and innovation was more pronounced in firms that had adopted the OHSMS certification. These findings are valuable to policymakers and corporate managers in emerging economies through corroborating the important role of workforce sustainability in facilitating firm innovation.
- Publikační typ
- časopisecké články MeSH
Poinfarktová ruptura myokardu je vzácné a fatální postižení. U 60leté ženy s akutní prekordiální bolestí přetrvávající po dobu dvou hodin došlo k hemodynamickému kolapsu; byly potvrzeny akutní tamponáda a kardiogenní šok. U pacientky byla provedena urgentní perikardiotomie s použitím intraaortální balonkové kontrapulsace a infuzemi inotropních látek. Při akutní bolesti na hrudi je velmi důležitá diferenciální diagnóza. Pro záchranu pacienta má naprosto zásadní význam časné stanovení diagnózy a rychle provedená chirurgická intervence.
Postinfarction myocardial rupture is rare and fatal. A 60-year-old female developed hemodynamic collapse after 2-h acute precordial pains. Acute tamponade and cardiogenic shock were confirmed. The patient underwent urgent pericardiotomy under the aid of intraaortic balloon pump and inotropic infusions. The differential diagnosis of acute chest pain is important. An early diagnosis and prompt surgical intervention of acute tamponade are crucial for rescuing the patient.
- MeSH
- infarkt myokardu * diagnóza komplikace MeSH
- lidé středního věku MeSH
- lidé MeSH
- péče o pacienty v kritickém stavu MeSH
- perikardektomie metody MeSH
- ruptura srdce * diagnóza etiologie terapie MeSH
- srdeční tamponáda diagnóza komplikace terapie MeSH
- trombocytopenie etiologie komplikace MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
High-mobility group box 1 (HMGB1) is newly discovered protein, which play a crucial role in the pathogenesis of systemic inflammation. Recent studies showed that HMGB1 is one of the important pathophysiological mechanisms in the occurrence and development of atherosclerosis. The purpose of the present study was to investigate the relationship between serum HMGB1 levels and endothelial function in patients with polycystic ovary syndrome (PCOS). Eighty newly diagnosed patients with PCOS and eighty normal women of similar age were selected. Metformin treatment (1,500 mg/day) was initiated in all patients for a period of consecutive 3 months. Serum HMGB1 levels were measured by ELISA. High resolution ultrasound was used to measure the brachial artery diameter at rest, after reactive hyperemia (flow-mediated arterial dilation, FMD) and after sublingual glyceryltrinitrate. Serum HMGB1 levels in PCOS were 24.87+/-14.93 ng/ml, which were significantly higher than that in controls (8.82+/-3.55 ng/ml, p<0.01). After 3 months treatment, serum HMGB1 levels decreased significantly (p<0.05). By dividing the distribution of HMGB1 levels into quartiles, serum HMGB1 levels were increased gradually with the increase of testosterone levels (p<0.05), whereas the FMD levels decreased (p<0.05). Multiple stepwise linear regression analysis showed that FMD (estimated coefficient beta=-0.69, p=0.005), testosterone (beta=0.31, p=0.045), TBARS (beta=0.69, p=0.012) and hs-CRP levels (beta=0.68, p=0.001) were significantly associated with HMGB1. The absolute changes in HMGB1 showed a positive correlation with the changes in testosterone (p<0.05) and negative correlation with the changes in FMD (p<0.05) in patients with PCOS during the course of metformin therapy. Serum HMGB1 levels are correlated with endothelial dysfunction in patients with PCOS. Our study suggests that HMGB1 may contribute to the early stage of atherosclerosis in patients with PCOS.
- MeSH
- arteria brachialis diagnostické zobrazování metabolismus MeSH
- biologické markery krev MeSH
- cévní endotel diagnostické zobrazování metabolismus MeSH
- dospělí MeSH
- lidé MeSH
- mladý dospělý MeSH
- protein HMGB1 krev MeSH
- syndrom polycystických ovarií krev diagnostické zobrazování MeSH
- vazodilatace fyziologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladý dospělý MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
Layered double hydroxide (LDH) is one of the key host phases of Cr(VI) in the natural environment and chromite ore processing residue (COPR), causing serious pollution by Cr(VI). Therefore, efficient extraction or immobilization of the incorporated Cr(VI) in LDH is urgently needed. In this work, simultaneous separation and immobilization of Cr(VI) in LDH by using MgCl2·6H2O under thermal treatment is innovatively proposed. Cr was volatilized as CrCl3 and was immobilized as MgCr2O4 accounted for 62.2% and 37.8%, respectively, under the optimal condition (the mole ratio of Cl/Cr is 9, 700 °C and 120 min). The underlying reaction mechanisms are as follows: (i) HCl produced by MgCl2·6H2O accelerates the destruction of Cr(VI)-LDH layer structure, completely exposing the incorporated Cr(VI), (ii) Cr(VI) is reduced to Cr(III) by Cl-, part of which is directly immobilized as MgCr2O4, and the other part generates CrCl3, which is volatilized or further combined with Mg2+ to form MgCr2O4. The total Cr leaching concentration of the practical COPR sample treated by this method dramatically decreases from 421 to 0.7 mg/L, well below the landfill standard limit (4.5 mg/L). This work provides an attainable strategy for thorough remediation of COPR and inspires the treatment of heavy metal-containing LDH.
A new species of sponge-endosymbiotic shrimps, Periclimenoides tyrannodentatus, is described and illustrated. The species is remarkable for its stout subspatulate first pereiopods chelae with lateral fan-shaped pectination on their dactyli. Due to this character and simple ambulatory dactyli, the new species is similar to the type species of the genus, P. odontodactylus. Another remarkable character is in the unique shape of the minor chela of the second pereiopods; the distal cutting edges of its compressed fingers are distinctly expanded and armed with quite impressive dentitions. An identification key to the three currently recognised species of the genus Periclimenoides is provided. The new species represents the first record of the genus Periclimenoides from Taiwan.
- MeSH
- anatomické struktury zvířat MeSH
- Decapoda (Crustacea) MeSH
- Palaemonidae * MeSH
- rozšíření zvířat MeSH
- symbióza MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Taiwan MeSH
The remediation of Pb(II) through biomineralization is rergarded as a promising technique as well as an interesting phenomenon for transforming heavy metals from mobile species into very stable minerals in the environment. Studies are well needed for in-depth understanding the mechanism of Pb(II) immobilized by bacteria. In the present study, we investigated the uptake and biomineralization of Pb(II) using Bacillus cereus 12-2 isolated from lead-zinc mine tailings. The maximum Pb(II) uptake capacity of B. cereus 12-2 was 340 mg/g at pH 3.0. Zeta potential analyses and selective passivation experiments demonstrated that electrostatic attraction was the main force driving the uptake of Pb(II), while the carboxyl, amide and phosphate functional groups of the bacteria provided the binding sites for immobilizing Pb(II). XRD and TEM investigation revealed that the Pb(II) loaded on bacteria could be stepwise transformed into rod-shaped Ca2.5Pb7.5(OH)2(PO4)6 nanocrystal. Combined with protein denaturalization experiments, we proposed that the biomineralization of Pb(II) possibly consisted of two steps: (1) Rapid biosorption of Pb(II) on B. cereus 12-2 through the synergy of electrostatic attraction, ionic exchange and chelating activity of functional groups; (2) enzyme-mediated mineral transformation from amorphous precipitate to rod-shaped crystalline minerals happening gradually inside the bacteria.
STATEMENT OF PROBLEM: Fatigue failure of implant components is a common clinical problem. Plasma nitriding, an in situ surface-strengthening method, may improve fatigue properties of dental implants. PURPOSE: The purpose of this in vitro study was to evaluate the effect of plasma nitriding on the fatigue behavior of implant systems. MATERIAL AND METHODS: The preload and friction coefficient of plasma nitrided abutment screws, as well as settlement of the implant-abutment interface, were measured. Then, the reverse torque values and pullout force were evaluated after cyclic loading. Finally, the fatigue properties of the implant system were investigated with static fracture and dynamic fatigue life tests, and the morphology of the fracture on the surface of the implant system was observed. RESULTS: The plasma nitriding treatment reduced the friction coefficient; increased the preload, settlement value, reverse torque values, pullout force, and static fracture load; and prolonged fatigue life. Furthermore, abutment screws with plasma nitriding treatment showed a different fatigue fracture mode. CONCLUSIONS: Plasma nitriding improved mechanical performance and may be a suitable way to optimize the fatigue behavior of dental implants.
