• MeSH
• dieta MeSH
• řízení nemocnice MeSH

• MeSH
• Bacteria izolace a purifikace   MeSH
• hygiena práce MeSH
• kontaminace potravin analýza   MeSH
• potravinářská mikrobiologie MeSH
• Staphylococcus izolace a purifikace   MeSH

• MeSH
• nemoci zvířat MeSH
• veterinární lékařství MeSH

• Konspekt
• Veterinární lékařství
• NLK Obory
• veterinární lékařství
• NLK Publikační typ
• elektronické časopisy

• MeSH
• chemické techniky analytické metody   MeSH
• elektrochemie metody   MeSH
• kyanidy analýza   MeSH

The sensitivity of early life stages of common carp (Cyprinus carpio L.) to chronic exposure to single and combined environmental concentrations of the triazine metabolites terbuthylazine 2-hydroxy, terbuthylazine-desethyl and atrazine 2-hydroxy was evaluated under laboratory conditions. Their effects were assessed on lipid peroxidation, antioxidant enzymes (total superoxide dismutase, glutathione reductase, catalase, glutathione S-transferase, reduced glutathione), mortality, growth, development and histology. Single metabolites (terbuthylazine 2-hydroxy-0.73 μg/L; terbuthylazine-desethyl-1.80 μg/L; atrazine 2-hydroxy-0.66 μg/L) and combinations were not associated with negative effects on hatching, behaviour, embryo viability, growth or early ontogeny. Carp exposed to terbuthylazine-desethyl at 1.80 μg/L showed significantly lower total superoxide dismutase and glutathione reductase activity compared with the control group. Liver histology revealed diffused steatosis associated with the presence of lipid inclusions in hepatic cells in groups exposed to terbuthylazine-desethyl, atrazine 2-hydroxy and the tested combination of metabolites.

• MeSH
• antioxidancia metabolismus   MeSH
• atrazin metabolismus   toxicita   MeSH
• chemické látky znečišťující vodu metabolismus   toxicita   MeSH
• embryo nesavčí účinky léků   enzymologie   metabolismus   MeSH
• glutathion metabolismus   MeSH
• glutathionreduktasa metabolismus   MeSH
• glutathiontransferasa metabolismus   MeSH
• herbicidy metabolismus   toxicita   MeSH
• játra účinky léků   embryologie   patologie   MeSH
• kapři embryologie   metabolismus   MeSH
• katalasa metabolismus   MeSH
• látky reagující s kyselinou thiobarbiturovou metabolismus   MeSH
• oxidační stres účinky léků   MeSH
• peroxidace lipidů účinky léků   MeSH
• superoxiddismutasa metabolismus   MeSH
• triaziny metabolismus   toxicita   MeSH
• zvířata MeSH
• Check Tag
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

• MeSH
• zdravotnické prostředky MeSH

Toxicity of the neonicotinoid pesticide thiacloprid to embryos and larvae of common carp Cyprinus carpio was assessed under laboratory conditions. Carp embryos and larvae were exposed to thiacloprid at four concentrations: 4.5 (environmental concentration), 45, 225, and 450 μg/L for 35 days and compared to a non-treated control group. The effects on lipid peroxidation, antioxidant enzyme levels (superoxide dismutase, glutathione reductase, catalase, glutathione S-transferase, and reduced glutathione), mortality, growth, development, and histopathogenesis were assessed. Thiacloprid at tested concentrations were not associated with negative effects on hatching, behaviour, embryo viability, or Fulton's condition factor. Carp exposed to 45 μg/L thiacloprid showed lower weight and length compared to controls. Thiacloprid at 225 and 450 μg/L delayed development and led to lower weight and length of carp. Significantly lower superoxide dismutase and glutathione reductase activity was observed at all tested concentrations of thiacloprid compared with the control group. Chronic thiacloprid exposure of early-life stages of carp affected ontogeny and growth rate, and inhibited antioxidant capacity.

• MeSH
• antioxidancia metabolismus   MeSH
• chemické látky znečišťující vodu toxicita   MeSH
• embryo nesavčí účinky léků   enzymologie   MeSH
• kapři růst a vývoj   metabolismus   MeSH
• larva MeSH
• neonikotinoidy toxicita   MeSH
• peroxidace lipidů účinky léků   MeSH
• pesticidy toxicita   MeSH
• thiaziny toxicita   MeSH
• vztah mezi dávkou a účinkem léčiva MeSH
• zvířata MeSH
• Check Tag
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

• MeSH
• lékařská etika MeSH
• lidé MeSH
• nádory ženských pohlavních orgánů MeSH
• péče o umírající MeSH
• Check Tag
• lidé MeSH
• ženské pohlaví MeSH

OBJECTIVES: The present study aimed to assess the acute effect of cypermethrin on common carp (Cyprinus carpio). Evaluation of toxicity effects of cypermethrin on carp was performed on based assessment of hematological profile, antioxidant and oxidative biomarkers and histopathology. METHODS: For testing of toxicity was used the commercial product Cyperkill 25 EC - CY, which contains 250 g.L-1 of cypermethrin. Carp were exposed to two concentrations (1CY - 4.57 µg.L-1 and 2CY - 45.7 µg.L-1) of CY and a control for 96 hours. RESULTS: Significant reduction (p<0.05) in leukocyte count were in fish exposed to concentration 45.7 µg.L-1 (2CY). The both exposure of CY lead to significant differences (p<0.01) in antioxidants biomarkers (superoxide dismutase, catalase, glutathione reductase, reduced glutathione and glutathione S-transferase) and in lipid peroxidation in carp tissues. Many of these changes were observed in liver, gills, muscle, intestine, brain and kidney. Additionally, exposure to CY caused many histological changes in gills, liver and caudal kidney. CONCLUSION: Exposure to CY caused hematological, biochemical and histopathological changes in carp. This study provides and complements other important results for evaluating the toxicity effect of pyrethroids on fish.

• MeSH
• insekticidy toxicita   MeSH
• kapři metabolismus   MeSH
• pyrethriny toxicita   MeSH
• testy toxicity metody   MeSH
• zvířata MeSH
• Check Tag
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

OBJECTIVES: The aim of this study was to assess the toxicity of terbuthylazine in different developmental stages of common carp (Cyprinus carpio) on the basis of mortality, early ontogeny, occurrence of morphological anomalies, growth rate, and Fulton's condition factor during and at the conclusion of the test. DESIGN: The toxicity tests were performed on carp according to OECD 210 methodology. The developmental stages of carp were exposed to terbuthylazine at four concentrations, 2.9 (reported environmental concentration in Czech rivers); 70; 1,400; and 3,500 µg.L(-1) for 35 days and compared to carps in a non-treated control group. RESULTS: Terbuthylazine in concentration 1,400 and 3,000 µg.L(-1) caused significant (p<0.01) decrease of mass, total length and delayed in development of carp. Fish exposed to terbuthylazine showed alteration of tubular system of caudal kidney. On the basis of histopathological changes the values of LOEC=2.9 µg.L(-1) terbuthylazine were estimated. CONCLUSIONS: Chronic terbuthylazine exposure of early-life stages of common carp affected their growth rate, early ontogeny and histology. Some of the changes were observed only at higher exposures, but change founded in caudal kidney was affected in fish exposed to the real environmental concentration tested (i.e., 2.9 µg.L(-1)).

• MeSH
• chemické látky znečišťující vodu toxicita   MeSH
• embryo nesavčí účinky léků   MeSH
• kapři embryologie   MeSH
• ledviny účinky léků   embryologie   MeSH
• pesticidy toxicita   MeSH
• testy chronické toxicity MeSH
• triaziny toxicita   MeSH
• zvířata MeSH
• zygota účinky léků   MeSH
• Check Tag
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH