Ciba Foundation symposium ; 154
242 s. : obr., tab., bibliogr. přeruš.
- MeSH
- Anti-Bacterial Agents biosynthesis isolation & purification MeSH
- Bacteria chemistry metabolism MeSH
- Fungi chemistry metabolism MeSH
- Host-Parasite Interactions MeSH
- Antibiotics, Antineoplastic biosynthesis isolation & purification MeSH
- Antineoplastic Agents isolation & purification MeSH
- Drug Screening Assays, Antitumor MeSH
elektronický časopis
- Conspectus
- Farmacie. Farmakologie
- NML Fields
- farmacie a farmakologie
- NML Publication type
- elektronické časopisy
- Keywords
- houba, korálovec ježatý, protinádorová látka,
- MeSH
- Agaricales * chemistry MeSH
- Antidepressive Agents MeSH
- Gastrointestinal Agents MeSH
- Hypolipidemic Agents MeSH
- Immunologic Factors MeSH
- Humans MeSH
- Neuroprotection MeSH
- Neuroprotective Agents MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Cynomorium coccineum and Cynomorium songaricum are unusual parasitic plants in the family Cynomoriaceae characterized by their unusual appearance and way of life. Due to their special habit and extremely rare occurrence, in the past, various magical properties have been attributed to these plants. The plant Cynomorium coccineum, which is found in the Mediterranean, has been used in Europe since the Middle Ages in folk medicine under the name fungus maletensis (maltese fungus). It was used for the same purpose in Arabic cultures under the name tarthuth. The Asian species (Cynomorium songaricum), sometimes considered a subspecies of C. coccineum, is still used in traditional Chinese medicine under the name Suo Yang. Recent studies show that the plant has a number of beneficial effects on the body and there is a real possibility that the substances present in Suo Yang or substances derived therefrom will be used in the future for therapeutic purposes. Of particular interest are their effects on sexual function. Preclinical experiments in male rats showed an increase in fertility after administration of Cynomoriumextract. In these tests, an increase in the weight of the testes and an increase in the number of spermatozoa and their viability were observed. Cynomorium plants offer a new approach to the treatment of human infertility, which is currently a major problem.
- MeSH
- Cynomorium * MeSH
- Pharmacological Phenomena MeSH
- Phytochemicals * pharmacology therapeutic use MeSH
- Rats MeSH
- Humans MeSH
- Infertility, Male drug therapy MeSH
- Mice MeSH
- Spermatozoa drug effects MeSH
- Medicine, Traditional MeSH
- Check Tag
- Rats MeSH
- Humans MeSH
- Mice MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Při chirurgickém léčení chronické osteomyelitidy použili autoři k výplni osteomyelitické dutiny bioaktivní sklokeramický materiál BAS-0 a BAS-HA u 20 nemocných od roku 1993. Uvedený sklokeramický materiál byl před operací nasycen roztokem antibiotik (Bykomycin, Likomycin). Současně byla podána antibiotika celkově. Pro daný účel je nejvýhodnější porézní forma uvedených materiálů. Kvůli nedostatku porézní sklokeramiky byla použita denzní se zdánlivou porozitou 15 % u 11 operovaných a kombinace jemné drti materiálu BAS-0 a BAS-HA a fibrinového lepidla Beriplast u 4 operovaných. Kontrolováno bylo 19 pacientů; nejlepší výsledek byl dosažen při použití porézního materiálu, kde všichni 4 pacienti se zhojili. Délka sledování je u nich 4 roky a 7 měsíců. Při použití denzního materiálu se zhojilo přes 50 % operovaných. Horší výsledek byl při použití kombinace BAS-0 a BAS-HA s Beriplastem. Byly provedeny 3 reoperace. Diskutovány jsou výhody a nevýhody použití uvedených materiálů v léčení osteomyelitických dutin a perspektivy do budoucna.
Since 1993 the authors have applied in the surgical treatment of chronic osteomyelitis bioactive glass-ceramic material BAS-0 and BAS-HA for filling the osteomyelitic cavity in 20 patients. Prior to the operation the glass-ceramic material was saturated with ATB solution (Bycomycin, Lycomycin). At the same time ATB were administered also in general. The most suitable for the given purpose is the porouš form of the mentioned materials. Due to the lack of porous glass-ceramics, dense material was used with 15 % apparent porosity in 11 patients and a combination of fine cullet of BAS-0 and BAS-HA and Beriplast fibrin glue in 4 patients. 19 patients were followed up, the best result was achieved in the application of porous material when ail 4 patients healed. The period of follow up in these patients is 4 years and 7 months. After the application of dense material more than 50 % of patients healed. A worse result was recorded in the application of the combination of BAS-0 and BAS-HA with Beriplast.Three reoperations were performed.The authors discuss the pros and cons of the application of the mentioned materials in the treatment of osteomyelitic cavities and their prospect for the future.
- MeSH
- Anti-Bacterial Agents therapeutic use MeSH
- Biocompatible Materials MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Drug Carriers MeSH
- Osteomyelitis diagnosis surgery MeSH
- Aged MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Aged MeSH
- Publication type
- Case Reports MeSH
- Review MeSH
Chyawanprash (CP) is an Ayurvedic health supplement which is made up of a super-concentrated blend of nutrient-rich herbs and minerals. It is meant to restore drained reserves of life force (ojas) and to preserve strength, stamina, and vitality, while stalling the course of aging. Chyawanprash is formulated by processing around 50 medicinal herbs and their extracts, including the prime ingredient, Amla (Indian gooseberry), which is the world's richest source of vitamin C. Chyawanprash preparation involves preparing a decoction of herbs, followed by dried extract preparation, subsequent mixture with honey, and addition of aromatic herb powders (namely clove, cardamom, and cinnamon) as standard. The finished product has a fruit jam-like consistency, and a sweet, sour, and spicy flavor. Scientific exploration of CP is warranted to understand its therapeutic efficacy. Scattered information exploring the therapeutic potential of CP is available, and there is a need to assemble it. Thus, an effort was made to compile the scattered information from ancient Ayurvedic texts and treatises, along with ethnobotanical, ethnopharmacological, and scientifically validated literature, that highlight the role of CP in therapeutics. Citations relevant to the topic were screened.
Chronic inflammation with a wide spectrum of connected diseases (e [...].
- MeSH
- Phytochemicals pharmacology therapeutic use MeSH
- Humans MeSH
- Drug Discovery MeSH
- Gene Expression Regulation drug effects MeSH
- Signal Transduction drug effects MeSH
- Medicine, Chinese Traditional MeSH
- Inflammation drug therapy metabolism MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Introductory Journal Article MeSH
- Editorial MeSH
Ziziphora species represent the prototypical example of the Lamiaceae family. The phytochemicals present in Ziziphora include monoterpenic essential oils, triterpenes and phenolic substances belonging to the flavonoids. In Kazakh traditional medicine, Ziziphora species possess several medicinal uses. In particular, Z. bungeana Lam. and Z. clinopodioides Lam. are used for the treatment of illnesses related to the cardiovascular system or to combat different infections. Unfortunately, the majority of the information about the complex Ziziphora species is only available in Russian and Chinese language, therefore, we decided gather all available information on Kazakhstan Ziziphora, namely its content compounds, medicinal uses and published patents, to draw the attention of scientists to this very interesting plant with high medicinal potential.
- MeSH
- Biological Products chemistry isolation & purification pharmacology MeSH
- Flavonoids chemistry pharmacology MeSH
- Phytochemicals chemistry isolation & purification pharmacology MeSH
- Humans MeSH
- Oils, Volatile chemistry pharmacology MeSH
- Rhizophoraceae chemistry MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
432 s. : il.