Gambling encompasses a wide variety of activities, and the structural characteristics of each form contribute to its potential risk. However, the literature does not fully agree on the risk levels of certain gambling forms. In this study, we classify less risky gambling forms (soft forms) based on public perceptions of their riskiness. We examine the link between gambling experience and problem gambling prevalence. A survey was conducted in a model region of the Czech Republic, a post-socialist country with high gambling availability, with N = 2,498 respondents. A typology of gambling forms (lotteries, betting, and casino games) was created based on perceived risk similarities. Lotteries are the most frequently played gambling form, with 86.3% reporting lifetime participation. Among those who exclusively engage in lottery-type forms, 15 percentage points more women than men participated in the last year, and the gap widens to 31 points over a lifetime. Forms of gambling perceived as more risky show a lower proportion of non-problem gamblers, both for recent and lifetime participation. Furthermore, individuals who gambled within the past month or year are at higher risk of developing gambling problems compared to those whose gambling experiences were less recent.

• MeSH
• Adult MeSH
• Gambling * psychology   classification   epidemiology   MeSH
• Middle Aged MeSH
• Humans MeSH
• Young Adult MeSH
• Behavior, Addictive * psychology   epidemiology   classification   MeSH
• Prevalence MeSH
• Surveys and Questionnaires MeSH
• Risk-Taking * MeSH
• Risk Factors MeSH
• Aged MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Young Adult MeSH
• Male MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Czech Republic MeSH

BACKGROUND AND OBJECTIVE: Apalutamide (APA) is a treatment for metastatic castration-sensitive prostate cancer (mCSPC). In the ARON-3 study we investigated real-world experiences with APA treatment for mCSPC. METHODS: We retrospectively assessed real-world clinical outcomes for patients with mCSPC treated with APA in the ARON-3 study. Overall survival (OS) was calculated from APA initiation to death from any cause. PSA90 was defined as a prostate-specific antigen decline of ≥90% from baseline, and PSA0.2 as achievement of a PSA level ≤0.2 ng/ml. Data for adverse events were retrospectively collected from electronic and paper charts and categorized according to Common Terminology Criteria for Adverse Events v5.0. KEY FINDINGS AND LIMITATIONS: We included 531 patients with mCSPC treated with APA. High-volume disease was reported for 214 patients (40%), and 56 (11%) had visceral metastases. Median OS was not reached. PSA90 was experienced by 461 patients (87%) and PSA0.2 by 368 (69%). Median OS was significantly longer for patients with PSA90 or PSA0.2 than for subjects without these responses (p < 0.001). The incidence of grade 3-4 fatigue was higher among elderly patients (≥80 yr) than among younger patients (19% vs 5%), but the incidence of other adverse events was comparable between the age groups. CONCLUSIONS AND CLINICAL IMPLICATIONS: APA is an effective and tolerable treatment for mCSPC in the real-world setting. PATIENT SUMMARY: The ARON-3 project collects data for patients with prostate cancer treated in multiple centers worldwide to assess outcomes in the real-world setting. We analyzed data for patients with metastatic hormone-sensitive prostate cancer receiving apalutamide. Our results show that apalutamide is a safe and effective drug in the real-world setting as well as in clinical trials.

• MeSH
• Middle Aged MeSH
• Humans MeSH
• Neoplasm Metastasis MeSH
• Prostatic Neoplasms, Castration-Resistant drug therapy   pathology   mortality   MeSH
• Prostate-Specific Antigen blood   MeSH
• Antineoplastic Agents therapeutic use   MeSH
• Retrospective Studies MeSH
• Aged, 80 and over MeSH
• Aged MeSH
• Thiohydantoins * therapeutic use   MeSH
• Treatment Outcome MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Aged, 80 and over MeSH
• Aged MeSH
• Publication type
• Journal Article MeSH
• Multicenter Study MeSH

OBJECTIVES: This study aims to explore the lasting effects of stress experienced by pregnant women during World War II (WWII) on body and head measurements of their adult daughters. METHODS: The research sample consists of 336 female university students born in Poland between 1925 and 1951. The data include body measurements and socioeconomic information (parental occupation and number of siblings) acquired from questionnaires collected between the 1950s and 1970s. Student's t-test, Mann-Whitney test and Analysis of Variance were used to analyze differences in body measurements between groups of women born before and during the war, as well as the possible influences of socioeconomic variables. RESULTS: The mean measurements of body height, symphysion height, and waist circumference were lower in women conceived and born during the war compared to those born in the pre-war period. In contrast, the mean measurements of biacromial (shoulder) width, trunk length, and three head dimensions were higher in women conceived and born during the war. Additionally, the number of siblings appeared to be a significant factor that may have influenced the body measurements of women in both groups. For instance, a higher number of living siblings, particularly sisters, was associated with reduced body dimensions, such as body height and waist circumference, while a greater number of deceased siblings was linked to an increase in certain body dimensions. CONCLUSION: The results suggest that war-related prenatal conditions may have influenced the postnatal growth and development of women conceived and born during the war. Notably, the direction of these changes varied, which indicates that the growth response to the war-related conditions was a complex adaptation, reflecting both positive and negative changes in different body parts, rather than a uniform pattern of growth suppression.

• MeSH
• World War II * MeSH
• Adult MeSH
• Humans MeSH
• Young Adult MeSH
• Stress, Psychological MeSH
• Socioeconomic Factors MeSH
• Pregnancy MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Young Adult MeSH
• Pregnancy MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Poland MeSH

OBJECTIVES: To develop a gadolinium-free MRI-based diagnosis prediction decision tree (DPDT) for adult-type diffuse gliomas and to assess the added value of gadolinium-based contrast agent (GBCA) enhanced images. MATERIALS AND METHODS: This study included preoperative grade 2-4 adult-type diffuse gliomas (World Health Organization 2021) scanned between 2010 and 2021. The DPDT, incorporating eleven GBCA-free MRI features, was developed using 18% of the dataset based on consensus readings. Diagnosis predictions involved grade (grade 2 vs. grade 3/4) and molecular status (isocitrate dehydrogenase (IDH) and 1p/19q). GBCA-free diagnosis was predicted using DPDT, while GBCA-enhanced diagnosis included post-contrast images. The accuracy of these predictions was assessed by three raters with varying experience levels in neuroradiology using the test dataset. Agreement analyses were applied to evaluate the prediction performance/reproducibility. RESULTS: The test dataset included 303 patients (age (SD): 56.7 (14.2) years, female/male: 114/189, low-grade/high-grade: 54/249, IDH-mutant/wildtype: 82/221, 1p/19q-codeleted/intact: 34/269). Per-rater GBCA-free predictions achieved ≥ 0.85 (95%-CI: 0.80-0.88) accuracy for grade and ≥ 0.75 (95%-CI: 0.70-0.80) for molecular status, while GBCA-enhanced predictions reached ≥ 0.87 (95%-CI: 0.82-0.90) and ≥ 0.77 (95%-CI: 0.71-0.81), respectively. No accuracy difference was observed between GBCA-free and GBCA-enhanced predictions. Group inter-rater agreement was moderate for GBCA-free (0.56 (95%-CI: 0.46-0.66)) and substantial for GBCA-enhanced grade prediction (0.68 (95%-CI: 0.58-0.78), p = 0.008), while substantial for both GBCA-free (0.75 (95%-CI: 0.69-0.80) and GBCA-enhanced (0.77 (95%-CI: 0.71-0.82), p = 0.51) molecular status predictions. CONCLUSION: The proposed GBCA-free diagnosis prediction decision tree performed well, with GBCA-enhanced images adding little to the preoperative diagnostic accuracy of adult-type diffuse gliomas. KEY POINTS: Question Given health and environmental concerns, is there a gadolinium-free imaging protocol to preoperatively evaluate gliomas comparable to the gadolinium-enhanced standard practice? Findings The proposed gadolinium-free diagnosis prediction decision tree for adult-type diffuse gliomas performed well, and gadolinium-enhanced MRI demonstrated only limited improvement in diagnostic accuracy. Clinical relevance Even inexperienced raters effectively classified adult-type diffuse gliomas using the gadolinium-free diagnosis prediction decision tree, which, until further validation, can be used alongside gadolinium-enhanced images to respect standard practice, despite this study showing that gadolinium-enhanced images hardly improved diagnostic accuracy.

• MeSH
• Adult MeSH
• Gadolinium MeSH
• Glioma * diagnostic imaging   MeSH
• Contrast Media * MeSH
• Middle Aged MeSH
• Humans MeSH
• Magnetic Resonance Imaging * methods   MeSH
• Brain Neoplasms * diagnostic imaging   MeSH
• Predictive Value of Tests MeSH
• Reproducibility of Results MeSH
• Decision Trees * MeSH
• Aged MeSH
• Neoplasm Grading * MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH

INTRODUCTION: The objective of this study was to assess the impact of the Enhanced Recovery After Surgery (ERAS) programme implementation on treatment costs at a university-type centre, using the DRG scheme. MATERIALS AND METHODS: Retrospective analysis of patients' data in a group of 604 individuals enroled in the study. We evaluated three groups of patients according to the ERAS clinical protocol (CP): (1) CP oncogynaecology, (2) CP simple hysterectomy, (3) CP laparoscopy. The study aimed to evaluate the impact on the length of stay (LOS), savings in bed-days, and the reduction in direct treatment costs. Three parameters-antibiotic consumption, blood derivative consumption and laboratory test costs-were chosen to compare direct treatment costs. The statistical significance of the difference in the observed parameters was tested by a two-sample unpaired t test with unequal variances at the 0.05 significance level. RESULTS: We analysed data from 604 patients. In all three groups, the length of stay (LOS) was significantly reduced. The most significant reduction was observed in the CP oncogynaecology group, where the LOS was reduced from 11.1 days to 6.8 days (2022) and 7.6 days (2023) compared to 2019 (p < 0.05). Furthermore, there was a notable reduction in inpatient bed-days, which resulted in the capacity being made available to admit additional patients. A statistically significant reduction in direct costs was observed in the group of CP hysterectomy (antibiotic use) and in the CP laparoscopy (laboratory test costs). CONCLUSIONS: The implementation of the ERAS principles resulted in a number of significant positive economic impacts-reduction in the LOS and a corresponding increase in bed capacity for new patients. Additionally, direct treatment costs, including those related to antibiotic use or laboratory testing were reduced. The Czech Republic's acute healthcare system, like the majority of European healthcare systems, is financed by the DRG system. This flat-rate payment per patient encourages hospital management to seek cost-reduction strategies. The results of our study indicate that fast-track protocols represent a potential viable approach to reducing the cost of treatment while simultaneously meeting the recommendations of evidence-based medicine.

• MeSH
• Length of Stay statistics & numerical data   economics   MeSH
• Adult MeSH
• Gynecologic Surgical Procedures * economics   MeSH
• Hysterectomy economics   MeSH
• Diagnosis-Related Groups MeSH
• Laparoscopy economics   MeSH
• Middle Aged MeSH
• Humans MeSH
• Health Care Costs * statistics & numerical data   MeSH
• Retrospective Studies MeSH
• Aged MeSH
• Enhanced Recovery After Surgery * MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH

INTRODUCTION: Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder that frequently leads to end-stage renal disease. In this study, we examine the indications, procedures, and outcomes of native nephrectomy (NN) in ADPKD patients at our transplant center. Drawing on 25 years of clinical practice, we aim to provide insights into the surgical management of ADPKD, focusing on the specific factors influencing NN. MATERIALS AND METHODS: A retrospective study was conducted involving ADPKD patients who underwent KT and NN between 1999 and 2023. Collected data encompassed demographics and surgery parameters, such as duration, hospital stay length, blood loss, and complications. Patients were classified based on the urgency (acute/planned) of the NN and its type (unilateral/bilateral), followed by an analysis of the outcomes per group. RESULTS: Out of 152 patients post-KT for ADPKD, 89 (58.6%) underwent NN. The procedures were predominantly unilateral (71; 64%), with bilateral NN accounting for 40 (36%) cases. NN timing relative to KT was 31 (27.9%) pretransplant, 9 (8.1%) concomitant, 51 (45.9%) posttransplant, and 10 (9%) patients undergoing the sandwich technique. Acute NN were performed in 42 cases, while 69 were planned. Acute NNs were associated with longer surgeries, greater blood loss, and a higher incidence of perioperative complications compared to planned NNs. Specifically, unilateral acute NN had a 23.8% complication rate compared to 2.9% in planned cases; bilateral acute NN showed a 28.6% complication rate versus 4.3% in planned cases. CONCLUSION: This investigation accentuates the significance of planning and selection in NN for ADPKD, factoring in the heightened risk of complications. Acute NN are linked to worse outcomes, including higher rates of complications. The data emphasize the necessity of tailored surgical approaches based on individual patient circumstances.

• MeSH
• Time Factors MeSH
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Nephrectomy * methods   MeSH
• Polycystic Kidney, Autosomal Dominant * surgery   MeSH
• Postoperative Complications epidemiology   etiology   MeSH
• Retrospective Studies MeSH
• Kidney Transplantation * MeSH
• Treatment Outcome MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH

Cieľom štúdie je overenie psychometrických vlastností škály CAV, určenej na mapovanie skúseností s kyberagresiou a kyberviktimizáciou. Nástroj je tvorený 24 položkami rozdelenými do dvoch subškál: Kyberagresia (CAV-CB; 12 položiek) a Kyberviktimizácia (CAV-CV; 12 položiek). Výskumný súbor pozostával z N = 5 159 respondentov/tiek vo veku od 14 do 18 rokov (M = 16,06; SD = 1,159), pričom 51,3 % tvorili chlapci a 48,7 % dievčatá. Na overenie faktorovej štruktúry bola použitá konfirmačná faktorová analýza (CFA), aplikovaná metódou DWLS s robustnou korekciou, pričom posudzované boli štandardné indexy zhody. Na základe výsledkov analýz bol podporený dvojfaktorový model: χ2 (251) = 530,064; p < 0,001; CFI = 0,993; TLI = 0,992; RMSEA = 0,016 (90% CI: 0,014 – 0,018). Analýza invariancie merania bola vykonaná vzhľadom na rod a vek, pričom testované boli konfigurálna, metrická, skalárna a striktná invariancia. Hodnoty testov invariancie merania pri porovnaní podľa rodu a veku boli konzistentné so všetkými modelmi invariancie, čo umožňuje porovnávanie skóre medzi skupinami. Reliabilita škály bola hodnotená pomocou Cronbachovho α a McDonaldovho ω, pričom faktory mali uspokojivú vnútornú konzistenciu (CAV-CB: α = 0,907, ω = 0,908; CAV-CV: α = 0,920, ω = 0,921). Kyberagresia signifikantne korelovala s kyberviktimizáciou (r = 0,699; p < 0,001), čo naznačuje vzájomnú súvislosť medzi oboma faktormi. Percentilová distribúcia skóre v populácii dospievajúcich umožnila stanoviť orientačné normo-referenčné hranice pre subškály CAV-CB a CAV-CV, na základe ktorých bola vytvorená trojstupňová klasifikácia úrovne expozície určená na výskumné a preventívne účely.

The aim of this study was to evaluate the psychometric properties of the Cyber-Aggression and Cyber- Victimization Scale (CAV), which was developed to assess adolescents’ experiences with cyber-aggression and cyber-victimisation. The instrument consists of 24 items divided into two subscales: Cyber-aggression (CAV-CB; 12 items) and Cyber-victimization (CAV-CV; 12 items). The research sample comprised N = 5,159 adolescents aged 14 to 18 years (M = 16.06; SD = 1.159), with 51.3%boys and 48.7%girls. Confirmatory factor analysis (CFA) was used to assess the factor structure, employing the DWLS method with robust corrections and evaluating standard goodness-of-fit indices. The analysis supported a two-factor model: χ2 (251) = 530.064; p < .001; CFI = .993; TLI = .992; RMSEA = .016 (90% CI: .014–.018). Measurement invariance was tested across gender and age groups, including configural, metric, scalar, and strict invariance. Invariance testing results indicated acceptable fit for all models, supporting the comparability of scores across groups. Reliability was assessed using Cronbach’s alpha and McDonald’s omega, both indicating satisfactory internal consistency (CAV-CB: α = .907, ω = .908; CAV-CV: α = .920, ω = .921). Cyberaggression showed a significant correlation with cybervictimization (r = .699; p < .001), indicating a substantial relationship between the two constructs. The percentile distribution of scores in the adolescent population made it possible to establish provisional norm-referenced cut-off points for the CAV-CB and CAV- CV subscales, based on which a three-level classification of exposure was created for research and preventive purposes.

Druhá část článku se věnuje analýze praktických a legislativních aspektů návrhu zákona o paliativní péči, rozhodování na konci života a eutanázii. Navazuje na první část, která zkoumala historické, filozofické a právní základy, a rozvíjí diskusi o konkrétních otázkách, které tento návrh vyvolal ve veřejné i odborné debatě. Článek rozebírá ústavněprávní rámec asistované smrti, včetně aktuální judikatury Ústavního soudu ČR zabývající se otázkou práva na život, práva na sebeurčení, práva na respektování lidské důstojnosti a jejich vztahu k asistované smrti. Dále se zabývá otázkou možností zneužití asistované smrti s ohledem na českou a zahraniční medicínskou praxi a obhajuje návrh zákona s ohledem na zahraniční zkušenosti a dopady. Zamýšlí se nad tím, proč návrh zákona počítá s oběma formami asistované smrti, tedy i s aktivní vyžádanou eutanázií, i s asistovaným sebeusmrcením. Důležitým tématem článku je i vztah paliativní péče a asistované smrti a jejich možné legislativní propojení. Autor se věnuje též komparaci různých zahraničních modelů kontroly, zejména modelu ex ante ve Španělsku a ex post v Nizozemsku, a zkoumá etické a právní důsledky přenesení odpovědnosti z jednotlivce na instituci. Článek se vymezuje vůči některým výtkám soudních i odborných autorit vůči návrhu zákona, v závěru jsou pak shrnuty možnosti de lege ferenda. Autor v článku také poukazuje na významný lidskoprávní aspekt asistované smrti, a to respekt k osobní autonomii a důstojnosti člověka i v jeho rozhodování v závěru života.

The second part of the article is devoted to analyzing the practical and legislative aspects of the draft law on palliative care, decision-making at the end of life, and euthanasia. It follows from the first part, which examined the historical, philosophical, and legal foundations, and develops a discussion of specific issues that this proposal has raised in the public and professional debate. The article analyzes the constitutional and legal framework of assisted death, including the current case law of the Constitutional Court of the Czech Republic dealing with the issue of the right to life, the right to self-determination, the right to respect for human dignity, and their relationship to assisted death. It also deals with the issue of the possibilities of abuse of assisted death concerning Czech and foreign medical practice. It defends the draft law with regard to foreign experience and impacts. It considers why the draft law includes both forms of assisted death, i.e., both actively requested euthanasia and assisted suicide. The article's essential topic is also the relationship between palliative care and assisted death and their possible legislative connection. The author also compares various foreign control models, especially the ex ante model in Spain and the ex post model in the Netherlands, and examines the ethical and legal consequences of transferring responsibility from the individual to the institution. The article addresses some of the criticisms of judicial and expert authorities against the draft law, and in the conclusion, summarizes the possibilities of de lege ferenda. It emphasizes respect for personal autonomy and human dignity, including in their decision-making at the end of life.

Studie se zabývá čtvrtživotní krizí, která je charakteristická přehodnocováním identity, životního směřování a rozhodnutí a může se objevovat u lidí v mladé dospělosti. Ve studii vycházíme z modelu O. C. Robinsona, který popisuje dva typy krize: vymknutí (locked-out), který se objevuje spíše na začátku mladé dospělosti a uzamčení (locked-in), které je typičtější pro druhou polovinu období. Cílem studie bylo zjistit častost výskytu čtvrtživotní krize a rozdíly v psychosociálním fungování lidí ve dvou věkových skupinách (18 až 29 let a 30 až 40 let), vzhledem k jejímu prožívání. Soubor tvořilo 514 lidí ve věku 18 až 29 let a 152 lidí ve věku 30 až 40 let (73,9 % žen), kteří vyplnili online dotazníkovou baterii zjišťující prožívání čtvrtživotní krize (DCQ-12), spokojenosti se životem (SWLS), sociální oporu (MOS), smysl života (MLQ), prožívaný stres (PSS) a negativní emotivitu (PHQ-9; ve smyslu úzkosti a deprese). Zjistili jsme, že krizi častěji prožívali lidé ve věku 18 až 29 let (33,7 % vs. 18,4 % u lidí 30 až 40 let). Srovnání psychosociálního fungování těchto dvou věkových skupin podle (ne)přítomné čtvrtživotní krize ukázalo, že lidé ve věku od 18 do 29 let s přítomnými projevy krize měli nižší spokojenost se životem, vyšší úroveň stresu a úzkosti. Lidé ve věku od 30 do 40 let se lišili pouze v úrovni prožívané úzkosti, která byla vyšší opět u lidí s přítomnými projevy krize.

The study explores the quarter-life crisis, characterised by a re-evaluation of identity, life direction, and decisions, which can manifest during young adulthood. In this study, we draw on O. C. Robinson's model, which describes two types of crisis: the "locked-out" crisis, typically occurring in the early stages of young adulthood, and the "locked-in" crisis, more common in its later stages. The primary objective was to assess the prevalence of the quarter-life crisis and examine the differences in psychosocial functioning between two age groups (18 to 29 and 30 to 40) with respect to their experience of the crisis. The sample comprised 514 people between 18 and 29 years of age and 152 between 30 and 40 years of age (73.9% female), who completed an online questionnaire battery. These assessed the experience of the quarter-life crisis (DCQ-12), life satisfaction (SWLS), social support (MOS), meaning in life (MLQ), perceived stress (PSS), and negative emotionality (PHQ-9; anxiety and depression). The findings revealed that the quarter-life crisis was more prevalent among participants aged 18 to 29 (33.7%) compared to those aged 30 to 40 (18.4%). When comparing the psychosocial functioning of the two age groups based on the presence or absence of the crisis, people aged 18 to 29 experiencing the crisis reported lower life satisfaction, higher stress, and greater levels of anxiety. In contrast, participants aged 30 to 40 differed only in anxiety levels, which were higher among those experiencing the crisis.

PURPOSE: Auditory complications are potential side effects from childhood cancer treatment. Yet, limited evidence exists about the impact of auditory complications-particularly tinnitus-on health-related quality of life (HRQoL) among childhood cancer survivors (CCS). We determined the prevalence of hearing loss and tinnitus in the European PanCareLIFE cohort of CCS and examined its effect on HRQoL. METHODS: We included CCS from four European countries who were diagnosed at age ≤ 18 years; survived ≥ 5 years; and aged 25-44 years at study. We assessed HRQoL (Short Form 36), hearing loss, and tinnitus using questionnaires. We used multivariable linear regression to examine associations between these two auditory complications and HRQoL adjusting for socio-demographic and clinical factors. RESULTS: Our study population consisted of 6,318 CCS (53% female; median age at cancer diagnosis 9 years interquartile range [IQR] 5-13 years) with median age at survey of 31 years (IQR 28-35 years). Prevalence was 7.5% (476/6,318; confidence interval [CI]: 6.9-8.2) for hearing loss and 7.6% (127/1,668; CI: 6.4-9.0) for tinnitus. CCS with hearing loss had impaired physical (coefficient [coef.] -4.3, CI: -7.0 to -1.6) and mental (coef. -3.2, CI: -5.5 to -0.8) HRQoL when compared with CCS with normal hearing. Tinnitus was associated with impaired physical (coef. -8.2, CI: -11.8 to -4.7) and mental (coef. -5.9, CI: -8.8 to -3.1) HRQoL. CONCLUSION: We observed reduced HRQoL among CCS with hearing loss and tinnitus. Our findings indicate timely treatment of hearing loss and tinnitus may contribute to quality of life of survivors. IMPLICATIONS FOR CANCER SURVIVORS: CCS who experience auditory complications should be counseled about possible therapeutic and supportive measures during follow-up care.

• MeSH
• Child MeSH
• Adult MeSH
• Cohort Studies MeSH
• Quality of Life * MeSH
• Humans MeSH
• Adolescent MeSH
• Young Adult MeSH
• Neoplasms * complications   psychology   MeSH
• Hearing Loss * epidemiology   etiology   MeSH
• Child, Preschool MeSH
• Prevalence MeSH
• Cancer Survivors * psychology   MeSH
• Surveys and Questionnaires MeSH
• Tinnitus * etiology   epidemiology   MeSH
• Check Tag
• Child MeSH
• Adult MeSH
• Humans MeSH
• Adolescent MeSH
• Young Adult MeSH
• Male MeSH
• Child, Preschool MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Europe MeSH