Autori definujú v článku pojem katétrovej sepsy aj iné pojmy súvisiace s infekciou v oblasti centrálneho žilového katétra. Zaoberajú sa jej patogenézou, rizikovými faktormi a prevenciou.

The authors present the definition of catheter – related sepsis and the definitions of the other catheter – related infections. They present the pathogenesis, risk factors a prevention of catheter – related sepsis.

• MeSH
• Child MeSH
• Cross Infection prevention & control   MeSH
• Catheterization, Central Venous methods   utilization   MeSH
• Infection Control MeSH
• Humans MeSH
• Critical Care methods   utilization   MeSH
• Risk Factors MeSH
• Sepsis prevention & control   MeSH
• Catheters, Indwelling microbiology   adverse effects   utilization   MeSH
• Check Tag
• Child MeSH
• Humans MeSH

• MeSH
• Pulmonary Disease, Chronic Obstructive genetics   immunology   therapy   MeSH
• Virulence Factors MeSH
• Disease Management MeSH
• Publication type
• Meeting Abstract MeSH
• Collected Work MeSH

• Conspectus
• Patologie. Klinická medicína
• NML Fields
• pneumologie a ftizeologie

• MeSH
• Phlebography MeSH
• Catheterization, Central Venous adverse effects   MeSH
• Thrombophlebitis diagnosis   prevention & control   therapy   MeSH
• Publication type
• Review MeSH

• MeSH
• Amyloid metabolism   MeSH
• Amyloidosis diagnosis   etiology   MeSH
• Diagnosis, Differential MeSH
• Adult MeSH
• Humans MeSH
• Multiple Myeloma diagnosis   etiology   MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Female MeSH
• Publication type
• Case Reports MeSH

Plants protect themselves from pathogen invasion through the local expression of a variety of pathogenesis-related proteins. They are highly diverse in both primary structure and length, and exhibit different direct antimicrobial activity. This text reviews the knowledge of osmotin, antimicrobial protein involved in innate immunity of plants. Osmotin belongs to the fifth class of the group of pathogenesis-related (PR) proteins and has been found in different plants species, in every case osmotin is cysteine-rich protein involved in plant defense responses to several pathogens and abiotic stresses. The phylogenetic tree of amino acids compositions of osmotins from different plant species is presented and the basic similarities of clusters are discussed in this review. Osmotin gene is activated by different biotic as well as abiotic signals and has many functions. The review summarizes biochemical and structural properties, induction, functions and structural homology between osmotin and other proteins. Recent data about recombinant production in bacterial and plant cells are examined. The article indicates possible ways of osmotin application in research in the field of functional biology, medicine and agriculture.

• MeSH
• Antifungal Agents chemistry   immunology   pharmacology   MeSH
• Phylogeny MeSH
• Stress, Physiological MeSH
• Plants, Genetically Modified MeSH
• Fungi drug effects   MeSH
• Models, Molecular MeSH
• Plant Diseases immunology   MeSH
• Gene Expression Regulation, Plant * MeSH
• Recombinant Proteins genetics   immunology   pharmacology   MeSH
• Plant Proteins genetics   immunology   pharmacology   MeSH
• Salinity MeSH
• Protein Structure, Secondary MeSH
• Nicotiana genetics   immunology   microbiology   MeSH
• Protein Structure, Tertiary MeSH
• Water-Electrolyte Balance MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH
• Review MeSH

Nemoc asociovaná s IgG4 je nově rozpoznané systémové fibroinflammatorní onemocnění, které svými pestrými klinickými projevy napodobuje mnohá nádorová, zánětlivá a infekční onemocnění. Histopatologicky je charakterizováno hustým lymfoplazmocytárním infiltrátem bohatým na IgG4-pozitivní plazmatické buňky, vírovitě uspořádanou – storiformní – fibrózou, obliterující flebitidou, a také je často (ne vždy) provázeno zvýšenou sérovou koncentrací IgG4. Nemoc asociovaná s IgG4 obvykle dobře odpovídá na terapii kortikosteroidy.

IgG4-related disease is a recently recognized systemic fibroinflammatory disorder, which mimics many malignant, inflammatory and infectious diseases. Almost any organ can be affected. This condition is characterized by dense lymphoplasmatic infiltrate rich in IgG4-positive plasma cells, storiform fibrosis, obliterative phlebitis and prominently (but not always) elevated serum IgG4 concentrations. IgG4-related disease generally good responds to glucocorticoids therapy.

• Keywords
• imunoglobulin G4, nemoc asociovaná s IgG4, autoimunitní pankreatitis,
• MeSH
• Hypersensitivity genetics   pathology   MeSH
• Diagnosis, Differential MeSH
• Immune System Phenomena MeSH
• Immunoglobulin G analysis   biosynthesis   classification   MeSH
• Disease Attributes MeSH
• Humans MeSH
• Pancreatitis * diagnosis   etiology   immunology   pathology   MeSH
• Pathologic Processes MeSH
• Antibodies isolation & purification   MeSH
• Serologic Tests utilization   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

OBJECTIVES: To review clinical and laboratory findings in patients with SARS-Cov-2 (COVID-19) related acute pancreatitis. METHODS: This systematic review was based on a database search for articles of COVID-19 related acute pancreatitis in adult patients with confirmed COVID-19 infection that included age, gender, presenting symptoms, the onset of symptoms, laboratory values, imaging findings and exclusion of common causes of pancreatitis. RESULTS: Altogether 35 articles comprising 37 patients were included. Acute pancreatitis was the first presentation of COVID-19 in 43% of patients, concurrent with general or respiratory symptoms in 14% of patients or delayed after general or pulmonary symptoms by an average of 10 ± 5 d (range, 1 - 19 d) in 43% of patients. Serum amylase and lipase levels were elevated in 87% and 100% of patients. In 50% and 84%, amylase and lipase levels exceeded three-fold the upper normal limit. Pancreatic necrosis was reported in 6% of patients and in 12% of patients, the pancreas appeared normal. Three patients died. CONCLUSIONS: We conclude that the bi-modal pattern of the onset of symptoms supports both the cytotoxic and the immune-related pathogenesis of the pancreatic injury. Acute pancreatitis may be the first symptom of COVID-19 infection. Necrosis of the pancreas is rare.

• MeSH
• Acute Disease MeSH
• Amylases blood   MeSH
• COVID-19 complications   epidemiology   MeSH
• Adult MeSH
• Humans MeSH
• Lipase blood   MeSH
• Pancreas diagnostic imaging   MeSH
• Pancreatitis diagnosis   etiology   MeSH
• Tomography, X-Ray Computed methods   MeSH
• SARS-CoV-2 MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Publication type
• Journal Article MeSH
• Systematic Review MeSH

• MeSH
• Alcoholism MeSH
• Ethanol metabolism   MeSH
• Esophagus physiopathology   MeSH
• Pathology, Oral MeSH
• Intestine, Small physiopathology   MeSH
• Stomach physiopathology   MeSH
• Publication type
• Review MeSH

• MeSH
• Liver Cirrhosis, Alcoholic MeSH
• Ethanol metabolism   toxicity   MeSH
• Liver physiopathology   MeSH
• Pancreas physiopathology   MeSH
• Pancreatitis MeSH
• Publication type
• Review MeSH