In a retrospective anamnestic study a total of 3180 women teachers from primary schools in seven districts of the Czech Republic with a different incidence of statistically recorded reproductive disorders were examined. A professionally and socially homogeneous group was selected on purpose to standardize to a maximum extent exposure to detectable and undetectable risk factors and confounding factors in the working environment and living conditions. The respondents were classified according to their statements on smoking habits up to the age of 45 years, which was taken as the reproductive period. Although the majority of smokers belonged into the group of mild smokers with a mean consumption of 10 cigarettes per day, in this group significantly more frequent heavy menstrual bleeding, early and spontaneous abortions, deliveries of premature infants and infants born in term but with a low birthweight were recorded. Smokers had significantly more often induced abortions of unwanted pregnancies in the case-history as compared with non-smokers. After elimination of women who by the time of the survey had never been pregnant yet, heavy smokers, as compared with non-smokers had a more than twofold risk as regards difficulty to become pregnant, of spontaneous abortions, deliveries of premature infants: there was an almost double risk of delivery of a low birthweight infant even among medium heavy smokers. This work was supported by the Grant Agency of the Czech Republic - grant No. 313/94/0492

• MeSH
• dospělí MeSH
• komplikace těhotenství MeSH
• kouření MeSH
• látky působící na reprodukci MeSH
• lidé středního věku MeSH
• lidé MeSH
• průzkumy a dotazníky MeSH
• reprodukční zdraví MeSH
• senioři MeSH
• ženy MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• srovnávací studie MeSH

• MeSH
• hormony štítné žlázy analýza   krev   MeSH
• jod analýza   moč   MeSH
• lidé MeSH
• štítná žláza anatomie a histologie   imunologie   metabolismus   MeSH
• struma metabolismus   MeSH
• těhotenství fyziologie   metabolismus   MeSH
• ultrasonografie metody   využití   MeSH
• životní prostředí a veřejné zdravotnictví analýza   škodlivé účinky   MeSH
• Check Tag
• lidé MeSH
• těhotenství fyziologie   metabolismus   MeSH
• ženské pohlaví MeSH
• Geografické názvy
• Slovenská republika MeSH

• MeSH
• deprese terapie   MeSH
• příznaky a symptomy MeSH
• rozmnožování MeSH
• věkové faktory MeSH
• ženy MeSH

• MeSH
• antikoncepce metody   MeSH
• dospělí MeSH
• kontraceptiva orální kombinovaná kontraindikace   škodlivé účinky   MeSH
• lidé středního věku MeSH
• lidé MeSH
• nitroděložní antikoncepční prostředky MeSH
• premenopauza MeSH
• progesteron terapeutické užití   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• ženské pohlaví MeSH

In recent years there has been a noticeable "rejuvenation" of pelvic organ prolapse. Inconsistency of the pelvic floor muscles, including the omission of sexual organs, is extremely common pathology, observed almost a third of women of reproductive age. The search for effective, convenient methods of contraception for this category of patients is an important problem of modern gynecology. We proposed a method of transvaginal voluntary surgical contraception, produced in conjunction with surgical treatment of descent and prolapse of the vaginal walls. Studied the nearest and long-term results of surgery in 50 women to which, during the surgical treatment of genital prolapse at the same time was performed transvaginal occlusion of the fallopian tubes. Control groups consisted of 30 women to which in the first step before surgical correction of pelvic organ prolapse have been performed minilaparotomy and voluntary surgical sterilization (VSS). Our method consists in penetrating into the abdominal cavity through the anterior vaginal vault, downgrading the fallopian tubes with a hook of Ramathibodi and tubal sterilization by Pomeroy method. Intra - and postoperative complications were not observed. In the late postoperative periods - the effectiveness of the method was 100%. Marked tendency to improve the quality of sexual life tells about the positive impact of elimination of genital prolapse with simultaneous DCA on the quality of life of women.

• MeSH
• dospělí MeSH
• gynekologické chirurgické výkony metody   statistika a číselné údaje   MeSH
• lidé MeSH
• okluze terapeutická MeSH
• plastická chirurgie metody   statistika a číselné údaje   MeSH
• prolaps dělohy * chirurgie   MeSH
• sterilizace reprodukční metody   MeSH
• tubární sterilizace * metody   statistika a číselné údaje   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• ženské pohlaví MeSH
• Publikační typ
• hodnotící studie MeSH

• MeSH
• endokrinní žlázy fyziologie   MeSH
• nemoci endokrinního systému MeSH
• reprodukční techniky MeSH
• rozmnožování fyziologie   MeSH

• Konspekt
• Fyziologie člověka a srovnávací fyziologie
• NLK Obory
• endokrinologie
• reprodukční lékařství
• NLK Publikační typ
• kolektivní monografie

• MeSH
• neurosekreční systémy fyziologie   MeSH
• ovarium fyziologie   MeSH
• poškození DNA MeSH
• regulace genové exprese MeSH
• stárnutí fyziologie   MeSH
• volné radikály MeSH
• Publikační typ
• kongresy MeSH
• sborníky MeSH

• Konspekt
• Fyziologie člověka a srovnávací fyziologie
• NLK Obory
• reprodukční lékařství
• endokrinologie
• fyziologie

• MeSH
• endokrinní žlázy fyziologie   MeSH
• nemoci endokrinního systému patofyziologie   MeSH
• rozmnožování fyziologie   MeSH

• Konspekt
• Fyziologie člověka a srovnávací fyziologie
• NLK Obory
• endokrinologie
• reprodukční lékařství
• gynekologie a porodnictví

The significance of ABO blood system groups antigens in development of some malignant tumors is already established. The alteration of hormonal homeostasis must also be taken into account. Hence the aim of the investigation was to study ABO and Rh blood system antigens and hormonal status among reproductive age women with benign and malignant breast tumors. Methods: The determination of hormones was made by the enzymatic analysis method (ELAIZA), provided by proper ELAIZA kits. For the study of ABO and Rh­Hr system antigens, internationally recognized immunoserology methods were used. Results: High index of the breast gland tumors were revealed in patients with A(II) phenotypic group, according to the ABO system. The frequency distribution of O(I) phenotypic group was low among women with breast tumors. Among D, C, E, c and e antigens of the Rh system, the frequency of D and E antigens were increased in benign and malignant breast tumors patients. The study of hormonal balance revealed thyroid gland hypofunction and increased level of estradiol on the background of increased testosterone and decreased progesterone levels. Such hormonal imbalance and excess production of estradiol creates conditions for malignant tumor formation in reproductive age women. Conclusion: The highest frequency of breast cancer in reproductive age was revealed in A(II) group patients. The wide spectrum of hormonal disorders were revealed in breast tumor patients of the reproductive age, which was especially clear in cases of malignant tumor.

• MeSH
• ABO systém krevních skupin imunologie   krev   MeSH
• dospělí MeSH
• hormony štítné žlázy krev   MeSH
• kohortové studie MeSH
• krevní skupiny - systém Rh-Hr imunologie   krev   MeSH
• lidé středního věku MeSH
• lidé MeSH
• nádorové procesy MeSH
• nádory prsu * imunologie   krev   patofyziologie   MeSH
• pohlavní steroidní hormony krev   MeSH
• prolaktin krev   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• ženské pohlaví MeSH

The human reproduction has the monotocial element of K strategy (nidifungous) with mature newborn mammals and also of the r strategy (nidiculous) with immature mammals. There are questions about „contra naturam" antiselective practice in the treatment of extremely premature newborns. Allometric equations were calculated form 93 species of mammals: Mneo = 0.03374 M 0.946 and Gt = 68.536 M 0.225 (Mneo is the body weight of newborns in kg, M is the body weight of the female in kg and Gt is the gestational period in days). According to these allometric equations the birthweight of newborns is from 1100 g to 1600 g and gestational age is from 22.4 - 24. 5 weeks of gestation. The data from comparative zoology are in conformity with requirements of neonatologists to receive prematurity without further intra intrauterine pathologies. The postnatal care taken after extremely premature newborns replaces adaptive mechanisms which are present in immature mammalian newborns of r strategy. The neonatological practice has decreased the viability level to 24 weeks of gestation during the last 20 years. Further lowering to 22 weeks is possible in the near future.

• MeSH
• dítě MeSH
• dospělí MeSH
• lidé MeSH
• neonatologie MeSH
• novorozenec MeSH
• reprodukční lékařství MeSH
• selekce (genetika) MeSH
• těhotenství MeSH
• zralost orgánů plodu MeSH
• Check Tag
• dítě MeSH
• dospělí MeSH
• lidé MeSH
• novorozenec MeSH
• těhotenství MeSH
• ženské pohlaví MeSH