- MeSH
- Anticoagulants administration & dosage MeSH
- Antithrombins administration & dosage therapeutic use MeSH
- Dabigatran therapeutic use MeSH
- International Normalized Ratio standards MeSH
- Hemorrhage epidemiology chemically induced prevention & control MeSH
- Humans MeSH
- Pulmonary Embolism * drug therapy classification radiography MeSH
- Prothrombin Time standards MeSH
- Drug Administration Schedule MeSH
- Severity of Illness Index MeSH
- Tissue Plasminogen Activator administration & dosage MeSH
- Thrombolytic Therapy contraindications mortality standards MeSH
- Warfarin administration & dosage standards MeSH
- Check Tag
- Humans MeSH
Autoři podávají přehled o možnosti laboratorního monitorování nových perorálních antikoagulancií (přímých inhibitorů F Xa rivaroxabanu a apixabanu a přímého inhibitoru trombinu dabigatranu) v případě potřeby a volba příslušných koagulačních testů, které je dnes možné použít v klinické praxi.
An overview of the options for laboratory monitoring of the new oral anticoagulants (the direct Xa inhibitors rivaroxaban and apixaban and the direct thrombin inhibitor dabigatran), and selection of appropriate coagulation tests that can be used in clinical practice are presented.
- Keywords
- laboratorní testy, test inhibice faktoru Xa, Rotachrom test - anti FXa, apixaban,
- MeSH
- Anticoagulants * blood therapeutic use MeSH
- Antithrombins pharmacokinetics blood MeSH
- Administration, Oral * MeSH
- Benzimidazoles pharmacokinetics blood MeSH
- beta-Alanine analogs & derivatives pharmacokinetics blood MeSH
- Dabigatran MeSH
- Factor Xa analysis pharmacokinetics MeSH
- Blood Coagulation drug effects MeSH
- Factor Xa Inhibitors MeSH
- Humans MeSH
- Drug Monitoring methods standards MeSH
- Morpholines pharmacokinetics blood MeSH
- Prothrombin Time standards MeSH
- Pyrazoles pharmacokinetics blood MeSH
- Pyridones pharmacokinetics blood MeSH
- Reagent Kits, Diagnostic standards utilization MeSH
- Reference Values MeSH
- Rivaroxaban MeSH
- Thiophenes pharmacokinetics blood MeSH
- Thrombin Time standards MeSH
- Blood Coagulation Tests * standards MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
Damage control surgery j e soubor život zachraňujících, etapových úkonů k ošetření závažných nitrobřišních poranění. Cílem časného ošetření je omezení vlivu „smrtelné“ triády- acidózy, hypotermie, hypokoagulace. Definitivní ošetření poranění tkání je v tomto konceptu odsunuto až na okamžik hemodynamické a hemokoagulační stability poraněného.
Damage control surgery is a complex of life-saving, multiple-phase procedures for treating serious internal abdominal injuries. The goal of timely treatment is to limit the influence of the „trauma triad of death“- hypothermia, acidosis and coagulopathy. The definitive treatment of the injured tissues is, as per this concept, postponed until the patient is stable in terms of haemodynamics and haemocoagulation.
- MeSH
- Acidosis complications MeSH
- Time Factors MeSH
- Gastrointestinal Hemorrhage * etiology surgery MeSH
- Hemodilution adverse effects MeSH
- Hypothermia complications MeSH
- Blood Coagulation Disorders * etiology complications mortality prevention & control therapy MeSH
- Blood Transfusion methods MeSH
- Laparotomy methods MeSH
- Humans MeSH
- Partial Thromboplastin Time methods standards MeSH
- Abdominal Injuries * surgery complications MeSH
- Transfusion Reaction MeSH
- Prothrombin Time methods standards MeSH
- Check Tag
- Humans MeSH
- MeSH
- Monitoring, Ambulatory instrumentation MeSH
- Anticoagulants therapeutic use MeSH
- International Normalized Ratio MeSH
- Drug Monitoring instrumentation MeSH
- Prothrombin Time standards MeSH
- Quality Control MeSH
- Blood Coagulation Tests standards instrumentation MeSH
- Point-of-Care Systems standards MeSH
- Equipment and Supplies MeSH
- MeSH
- Risk Assessment MeSH
- International Normalized Ratio standards MeSH
- Blood Loss, Surgical prevention & control MeSH
- Coumarins administration & dosage pharmacokinetics pharmacology MeSH
- Humans MeSH
- Postoperative Complications prevention & control MeSH
- Preoperative Care MeSH
- Prothrombin Time standards MeSH
- Thromboembolism drug therapy prevention & control MeSH
- Check Tag
- Humans MeSH
- Keywords
- Novoseven, Kanavit, Prothromplex total,
- MeSH
- Algorithms MeSH
- Child MeSH
- Factor VIIa administration & dosage MeSH
- Risk Assessment MeSH
- Blood Transfusion MeSH
- Hemorrhage chemically induced classification therapy MeSH
- Humans MeSH
- Prothrombin administration & dosage MeSH
- Prothrombin Time standards MeSH
- Vitamin K 1 administration & dosage MeSH
- Warfarin administration & dosage adverse effects MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- MeSH
- Antiphospholipid Syndrome diagnosis etiology MeSH
- Anticoagulants administration & dosage adverse effects MeSH
- Heparin administration & dosage adverse effects MeSH
- Coumarins administration & dosage adverse effects MeSH
- Drug Resistance MeSH
- Humans MeSH
- Neoplasms diagnosis epidemiology complications MeSH
- Polymorphism, Genetic MeSH
- Prothrombin Time standards MeSH
- Recurrence MeSH
- Risk Factors MeSH
- Thromboembolism epidemiology etiology MeSH
- Warfarin administration & dosage adverse effects MeSH
- Check Tag
- Humans MeSH
- MeSH
- Anticoagulants administration & dosage MeSH
- Chemoprevention MeSH
- Heparin, Low-Molecular-Weight administration & dosage MeSH
- Humans MeSH
- Neoplasms complications MeSH
- Prothrombin Time standards MeSH
- Thromboembolism prevention & control therapy MeSH
- Check Tag
- Humans MeSH
- Publication type
- Randomized Controlled Trial MeSH