• MeSH
• Arteriosclerosis MeSH
• Biomedical Research MeSH
• Hemostasis MeSH
• Hyperlipidemias blood   MeSH
• Publication type
• Comparative Study MeSH

• MeSH
• Platelet Aggregation MeSH
• Publication type
• Congress MeSH

• Conspectus
• Patologie. Klinická medicína
• NML Fields
• hematologie a transfuzní lékařství

• MeSH
• Hemostasis MeSH
• Computers utilization   MeSH

Léčba antipsychotiky je spojena se zvýšeným rizikem vzniku žilní tromboembolické nemoci. Objevily se zprávy, že podávání některých antipsychotik souvisí s vyšším výskytem cerebrovaskulárních komplikací. Mechanizmy odpovědné za tyto nežádoucí účinky nejsou známy, ale přibývá vysvětlujících hypotéz. Krátce shrnujeme vliv hyperprolaktinémie v patogenezi zvýšené agregace destiček.

Treatment with antipsychotic drugs is associated with increased risk of venous thromboembolism. Administration of antipsychotics appears to be related to increased risk of cerebrovascular side effects. The biological mechanism responsible for this possible adverse drug reaction is uknown, but there is a growing number of elucidating hypotheses. We briefly review the arguments for the role of hyperprolactinemia in pathogenesis of platelet aggregation.

• MeSH
• Platelet Aggregation drug effects   MeSH
• Platelet Activation drug effects   MeSH
• Antipsychotic Agents pharmacology   blood   adverse effects   MeSH
• Cerebrovascular Disorders etiology   drug therapy   complications   MeSH
• Phenothiazines pharmacology   blood   adverse effects   MeSH
• Hyperprolactinemia drug therapy   chemically induced   complications   MeSH
• Humans MeSH
• Venous Thrombosis drug therapy   chemically induced   complications   MeSH
• Check Tag
• Humans MeSH

• MeSH
• Adrenergic beta-Antagonists adverse effects   MeSH
• Cholesterol blood   drug effects   MeSH
• Hemostasis drug effects   MeSH
• Hypotonic Solutions MeSH
• Humans MeSH
• Lipoproteins blood   drug effects   MeSH
• Check Tag
• Humans MeSH
• Male MeSH
• Female MeSH

• MeSH
• Platelet Aggregation Inhibitors MeSH
• Clinical Trials as Topic MeSH
• Coronary Disease MeSH
• Platelet Glycoprotein GPIIb-IIIa Complex MeSH

• Conspectus
• Patologie. Klinická medicína
• NML Fields
• kardiologie
• angiologie

• MeSH
• Anti-Inflammatory Agents MeSH
• Anticoagulants MeSH
• Neoplasms, Experimental MeSH
• Animal Experimentation MeSH
• Cricetinae MeSH
• Neoplasm Metastasis MeSH
• Propionates MeSH
• Check Tag
• Cricetinae MeSH

• MeSH
• Angina Pectoris drug therapy   MeSH
• Anti-Arrhythmia Agents MeSH
• Biomedical Research MeSH
• Adult MeSH
• Hemostasis drug effects   MeSH
• Middle Aged MeSH
• Humans MeSH
• Prostaglandins metabolism   MeSH
• Aged MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Aged MeSH
• Female MeSH

• MeSH
• Phenylbutyrates MeSH
• Hemostasis MeSH
• Vascular Diseases MeSH
• Blood Platelets physiopathology   MeSH

• MeSH
• Hemostasis analysis   MeSH
• Myocardial Infarction blood   MeSH