Objectives: Presentation of an overview of the reasons why data integration initiatives should be seen as enablers for effective decision support in data-intensive healthcare settings. Methods: Typical challenges rising from the information requirements of clinical decision support systems are highlighted. We then propose a methodological solution where several heterogeneous data sources are integrated by the means of a common data model on top of which the DSS is built. Results: We report on two successful case studies based on the DSSs developed in the context of the MobiGuide and Mosaic projects, funded by the European Union in the Seventh Framework Program. The MobiGuide patient guidance system has been successfully validated during a recent pilot study involving 30 patients (10 with atrial fibrillation and 20 with gestational diabetes), while Mosaic is currently undergoing a validation phase involving 1000 type 2 Diabetes patients. Conclusions: In the era of big data, effective data integration strategies are an essential need for medical informatics solutions and even more for those intended to support decision processes. Building generic DSSs based on a stable (but easily extensible) data model, specifically designed to meet the information requirements of DSSs and analytics, has proven to be a successful solution in the two presented use cases.

• Klíčová slova
• projekt MOSAIC, projekt MobiGuide,
• MeSH
• diabetes mellitus 2. typu diagnóza   terapie   MeSH
• fibrilace síní diagnóza   terapie   MeSH
• Health Level Seven MeSH
• informace pro uživatele zdravotní péče * MeSH
• lidé MeSH
• rozhodování pomocí počítače MeSH
• systémová integrace MeSH
• systémy pro podporu klinického rozhodování * MeSH
• teoretické modely MeSH
• zapojení pacienta MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• práce podpořená grantem MeSH

• MeSH
• big data * MeSH
• elektronické zdravotní záznamy organizace a řízení   MeSH
• kardiovaskulární rehabilitace metody   MeSH
• systémová integrace MeSH
• Publikační typ
• rozhovory MeSH
• Geografické názvy
• Izrael MeSH

Tato výzkumná studie hledá odpověď na otázku, jak různé psychoterapeutické výcviky zacházejí s integrací (nebo obecněji, s existující pluralitou teoretických perspektiv). Předkládané výsledky jsou založeny na kvalitativní analýze rozhovorů s reprezentanty sedmi českých výcvikových institutů, u nichž bylo možno předpokládat nějakou formu integrace. Koncepty vzniklé během analýzy jsou uspořádány do tří oblastí. První z nich, dimenze centrálnost vs. perifernost integrace, rozlišuje různé postoje, které mohou různé instituty vůči psychoterapeutické integraci zastávat. Druhá oblast se týká integrativní otevřenosti, ústředního konceptu celé analýzy, a také toho, čím je tato otevřenost omezována a ohraničována. Třetí oblast pak zachycuje utváření individuálního terapeutického stylu a jeho souvislost s integrací. V závěru je uvedeno několik praktických námětů vyplývajících z této analýzy.

This research study seeks to answer the question of how various psychotherapeutic trainings treat integration (or, more generally, the existing plurality of theoretical perspectives). Presented results are based on qualitative analysis of interviews with representatives of seven Czech training institutes, which were assumed to have adopted some form of integration. Concepts arising from the analysis are organized into three areas. The first one, centrality vs. peripherality dimension of integration distinguishes different attitudes that various institutes can hold towards psychotherapy integration. The second area involves the integrative openness, the central concept of the whole analysis, and also phenomena which set limits to this openness. The third area captures the formation of an individual therapeutic style and its association with integration. In conclusion, some practical suggestions arising from this analysis are presented.

• MeSH
• lidé MeSH
• odborný výcvik MeSH
• psychoanalytická terapie MeSH
• psychologie MeSH
• psychoterapie * metody   trendy   MeSH
• sběr dat MeSH
• výchova a vzdělávání MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• práce podpořená grantem MeSH

• MeSH
• automatizované zpracování dat MeSH
• mezinárodní spolupráce MeSH
• řízení zdravotnictví MeSH
• socialismus MeSH
• statistika jako téma MeSH
• Geografické názvy
• historické zeměpisné názvy MeSH

• MeSH
• dokumentace MeSH
• dostupnost zdravotnických služeb MeSH
• důvěrnost informací MeSH
• ekonomika a organizace zdravotní péče MeSH
• integrované poskytování zdravotní péče MeSH
• osobní údaje MeSH
• veřejné zdravotnictví - informatika MeSH
• zdravotní politika MeSH
• zdravotnické informační systémy MeSH

• Konspekt
• Veřejné zdraví a hygiena
• NLK Obory
• veřejné zdravotnictví
• ekonomie, ekonomika, ekonomika zdravotnictví
• NLK Publikační typ
• studie

Data integrity requirements in the pharmaceutical industry are more important and more urgent than ever before. This is due to the development, incessant changes and the tightening of the legislative requirements for the critical steps throughout the pharmaceutical product life cycle from research to commercial production, and must be accessible for further use. In addition, the data must be traceable and continuous in any pharmaceutical company during various phases of the product life cycle. The pharmaceutical industry should strategically consider the approach to the data integrity of computer systems related to Good Manufacturing Practice in order to meet the respective requirements of regulatory agencies.

• Klíčová slova
• integrita dat,
• MeSH
• farmaceutický průmysl * normy   MeSH
• léčivé přípravky normy   MeSH
• řízení kvality MeSH
• správnost dat MeSH

To improve patient outcomes after trauma, the need to decrypt the post-traumatic immune response has been identified. One prerequisite to drive advancement in understanding that domain is the implementation of surgical biobanks. This paper focuses on the outcomes of patients with one of two diagnoses: post-traumatic arthritis and osteomyelitis. In creating surgical biobanks, currently, many obstacles must be overcome. Roadblocks exist around scoping of data that is to be collected, and the semantic integration of these data. In this paper, the generic component model and the Semantic Web technology stack are used to solve issues related to data integration. The results are twofold: (a) a scoping analysis of data and the ontologies required to harmonize and integrate it, and (b) resolution of common data integration issues in integrating data relevant to trauma surgery.

• Publikační typ
• časopisecké články MeSH

Objectives: A significant portion of care related to cardiorespiratory diseases is provided at home, usually but not exclusively, after the discharge of a patient from hospital. It is the purpose of the present study to present the technical means which we have developed, in order to support the adaptation of the continuity of care of cardiorespiratory diseases at home. Methods: We have developed an integrated system that includes: first, a prototype laptop-based portable monitoring system that comprises low-cost commercially available components, which enable the periodical or continuous monitoring of vital signs at home; second, software supporting medical decision-making related to tachycardia and ventricular fibrillation, as well as fuzzy-rules-based software supporting home-ventilation optimization; third, a typical continuity of care record (CCR) adapted to support also the creation of a homecare plan; and finally, a prototype ontology, based upon the HL7 clinical document architecture (CDA), serving as basis for the development of semantically annotated web services that allow for the exchange and retrieval of homecare information. Results: The flexible design and the adaptable data-exchange mechanism of the developed system result in a useful and standard-compliant tool, for cardiorespiratory disease-related homecare. Conclusions: The ongoing laboratory testing of the system shows that it is able to contribute to an effective and low-cost package solution, supporting patient supervision and treatment. Furthermore, semantic web technologies prove to be the perfect solution for both the conceptualization of a continuity of care data exchange procedure and for the integration of the structured medical data.

• MeSH
• informační systémy normy   MeSH
• internet MeSH
• kardiovaskulární nemoci MeSH
• kontinuita péče o pacienty MeSH
• lidé MeSH
• sémantika MeSH
• služby domácí péče MeSH
• systémová integrace MeSH
• telemetrie metody   přístrojové vybavení   MeSH
• ukládání a vyhledávání informací metody   MeSH
• zajištění kvality zdravotní péče metody   MeSH
• Check Tag
• lidé MeSH