Druhově specifické rozdíly mezi jednotlivými medúzami mohou bránit ve volbě adekvátní lokální terapie a správnému poskytnutí první pomoci. Dodnes neexistuje univerzální protokol aplikabilní pro všechna poranění způsobená těmito živočichy. Přijetí bezpečných a účinných opatření a zásad první pomoci při žáhnutí medúzou je také komplikováno šířením celé řady neoficiálních zpráv a nedostatkem důkazů ve vědecké literatuře. Jedinou možností, jak z této situace uniknout, je postupná publikace kazuistik nebo sérií kazuistik s jednotícím léčebným konceptem tak, aby mohla být následně realizována klinická doporučení pro lokální terapii podložená dostatečným množství robustních dat.
Species-specific differences between individual jellyfish can prevent the choice of adequate local therapy and the correct provision of first aid. To date, there is no universal protocol applicable to all injuries caused by these marine animals. Adoption of safe and effective first aid measures for jellyfish stings is also complicated by a wide variety of unofficial reports and a lack of evidence in the scientific literature. The only way out of this situation is the gradual publication of case reports or a series of case reports with a unifying treatment concept so that clinical recommendations for local therapy supported by a sufficient amount of robust data can subsequently be implemented.
- MeSH
- Adult MeSH
- Cnidarian Venoms adverse effects toxicity MeSH
- Bites and Stings complications nursing MeSH
- Humans MeSH
- Nematocyst injuries MeSH
- Venom Hypersensitivity * complications nursing prevention & control MeSH
- Scyphozoa * MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Case Reports MeSH
Cestování do vzdálených zemí s sebou přináší četná rizika, včetně zdravotních. Kromě infekčních nemocí, alimentárních nákaz a úrazů jsou jedním z hlavních zdravotních rizik komplikace, vzniklé na základě „konfliktního kontaktu“ s jedovatých živočichem či jedovatými rostlinami. V první části našeho přehledu se zabýváme neurologickými komplikacemi stavů, které vzniknou při kontaktu s jedem některého z jedovatých živočichů.
Travelling to distant countries is associated with numerous risks, including some health-related ones. In addition to infectious diseases, alimentary infections, and injuries, complications arising from a “conflict contact” with a venomous animal or plant are among the major health-related risks. Part one of our review deals with neurological complications of conditions resulting from contact with the venom of some of the venomous animals.
- MeSH
- Scorpion Stings complications physiopathology therapy MeSH
- Animals, Poisonous * MeSH
- Bites and Stings MeSH
- Spider Bites complications physiopathology therapy MeSH
- Nervous System Diseases * MeSH
- Spider Venoms MeSH
- Scyphozoa pathogenicity MeSH
- Scorpion Venoms MeSH
- Snake Bites complications physiopathology therapy MeSH
- Publication type
- Review MeSH
Úvod. Popálenie medúzou nie je v strednej Európe časté. Prázdninová prímorská turistika však prináša aj na naše zdravotnícke pracoviská rôzne nezvyčajné chorobné prejavy. Kúpanie sa v mori je častou príčinou výskytu popálenia medúzou a zmien v koži, ktoré biopticky nie sú presne opísané. Cieľ. Autori sa zamerali na sledovanie morfologických a numerických zmien niektorých druhov zápalových buniek v koži 59-ročnej pacientky po 10 dňoch od popálenia medúzou. Na porovnanie kožných zmien sa jej na bioptické vyšetrenie odobrala lezionálna aj nelezionálna koža. Metódy. Obidve excízie kože sa skúmali pomocou imunohistochemických metód na detekciu antigénu CD68, CD163, CD30, CD4, CD3, CD8, CD20 a CD1a, na detekciu histiocytov, niektorých klonov lymfocytov a Langerhansových buniek kože prezentujúcich antigén, antigén CD117, toluidínová modrá a chlóracetátesteráza na detekciu mastocytov a neutrofilov. Materiál bol vyšetrený aj imunofluorescenčnými metódami na dôkaz IgA, IgM, IgG, C3, C4, albumínu a fibrinogénu. Reprezentatívne zorné polia sa dokumentovali mikroskopickým fotoaparátom Leica DFC 420 C. Získané snímky z obidvoch vzoriek kože sa spracovali morfometrickou analýzou pomocou softvéru Vision Assistant. Získané hodnoty boli spracované štatisticky metódou Studentovho t-testu. Výsledky. Priemerné hodnoty buniek v lezionálnej a v nelezionálnej vzorke boli nasledujúce - CD117-2,64/0,37, CD68-6,86/1,63, CD163-3,13/2,23, CD30- 1,36/0,02, CD4-3,51/0,32, CD8-8,22/0,50, CD3-10,69/0,66, CD20-0,56/0,66, CD1a-7,97/0,47. Mierne zmnožené boli eozinofily v lezionálnej koži. Zvýšené hodnoty sledovaných druhov buniek v lezionálnej excízii v porovnaní s nelezionálnou vzorkou kože boli v ôsmich prípadoch štatisticky významné na hladine p = 0,033 až 0,001. Štatisticky nevýznamný rozdiel bol dokázaný iba medzi hodnotami CD163+ histiocytov. Záver. Autori určili počty sledovaných zápalových buniek v lezionálnej koži po popálení medúzou a porovnali ich s nelezionálnou kožou pacientky. Zistili štatisticky významné zvýšenie hladiny vybraných zápalových buniek a numericky dokumentovali zmeny celularity v zápalovom ložisku spôsobené hypersenzitívnou reakciou po poranení medúzou v intervale 10 dní po ataku.
Introduction. Jellyfish burning is not commonly part of the professional finding in the central Europe health care laboratory. Holiday seaside tourism includes different and unusual presentations of diseases for our worklplaces. Sea water-sports and leisure is commonly connected with jellyfish burning and changes in the skin, that are not precisely described. Aim. Authors focused their research on detection of morphological and quantitative changes of some inflammatory cells in the skin biopsy of a 59-years-old woman ten days after a jellyfish stinging. Because of a comparison of findings the biopsy was performed in the skin with lesional and nonlesional skin. Methods. Both excisions of the skin were tested by imunohistochemical methods to detect CD68, CD163, CD30, CD4, CD3, CD8, CD20 a CD1a, to detect histiocytes, as well as several clones of lymphocytes and Langerhans cells (antigen presenting cells of skin), CD 117, toluidin blue and chloracetase esterase to detect mastocytes and neutrophils. Material was tested by immunofluorescent methods to detect IgA, IgM, IgG, C3, C4, albumin and fibrinogen. Representative view-fields were documented by microscope photocamera Leica DFC 420 C. Registered photos from both samples of the skin were processed by morphometrical analysis by the Vision Assistant software. A student t-test was used for statistical analysis of reached results. Results. Mean values of individual found cells in the sample with lesion and without lesion were as follows: CD117 -2.64/0.37, CD68-6.86/1.63, CD163-3.13/2.23, CD30-1.36/0.02, CD4-3.51/0.32, CD8-8.22/0.50, CD3-10.69/0.66, CD20-0.56/0.66, CD1a-7.97/0.47 respectively. Generally mild elevation of eosinofils in lesional skin was detected. Increased values of tested cells seen in excision from lesional skin when compared with nonlesional ones were statistically significant in eight case at the level p = 0.033 to 0.001. A not statistically significant difference was found only in the group of CD163+ histiocytes. Conclusion. Authors detected numbers of inflammatory cells in lesional skin after the stinging by a jellyfish and compared them with the numbers of cells in the nonlesional skin of the same patient. Statistically significant differences were seen in the level of selected inflammation cells and numerically documented changes of cellularity in the inflammatory focus were caused by a hypersensitivity reaction after jellyfish injury in the period of 10 days after attack.
- MeSH
- Immunohistochemistry utilization MeSH
- Dermatitis, Contact * diagnosis etiology pathology MeSH
- Bites and Stings MeSH
- Skin Manifestations MeSH
- Skin pathology MeSH
- Middle Aged MeSH
- Humans MeSH
- Scyphozoa MeSH
- Venoms * adverse effects MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
- Keywords
- medúza, žahavé buňky,
- MeSH
- Cnidaria * MeSH
- Animals, Poisonous MeSH
- Cnidarian Venoms * adverse effects MeSH
- Bites and Stings * prevention & control therapy MeSH
- Acetic Acid MeSH
- Humans MeSH
- Nematocyst MeSH
- Scyphozoa MeSH
- Venoms MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Geographicals
- Mediterranean Region MeSH
- MeSH
- Amebiasis diagnosis etiology therapy MeSH
- Anti-Bacterial Agents therapeutic use MeSH
- Cysticercosis diagnosis etiology therapy MeSH
- Dengue diagnosis etiology therapy MeSH
- Dermatitis diagnosis etiology drug therapy MeSH
- Dermatology methods MeSH
- Diagnosis, Differential MeSH
- Child MeSH
- Adult MeSH
- Dracunculiasis diagnosis etiology therapy MeSH
- Erythema diagnosis etiology therapy MeSH
- Drug Therapy methods utilization MeSH
- Filariasis diagnosis etiology drug therapy MeSH
- Hydrozoa pathogenicity MeSH
- Intertrigo etiology complications MeSH
- Anthozoa pathogenicity MeSH
- Bites and Stings etiology drug therapy complications MeSH
- Spider Bites diagnosis etiology therapy MeSH
- Larva Migrans diagnosis drug therapy transmission MeSH
- Leishmaniasis diagnosis etiology classification MeSH
- Humans MeSH
- Myiasis diagnosis etiology therapy MeSH
- Onchocerciasis, Ocular diagnosis etiology therapy MeSH
- Parasitic Diseases diagnosis etiology therapy MeSH
- Primary Prevention methods MeSH
- Scyphozoa pathogenicity MeSH
- Siphonaptera immunology pathogenicity drug effects MeSH
- Scorpions pathogenicity MeSH
- Tropical Medicine methods MeSH
- Trypanosomiasis diagnosis etiology therapy MeSH
- Trypanosomiasis, African diagnosis etiology drug therapy MeSH
- Venereology methods MeSH
- Virus Diseases etiology classification therapy MeSH
- Ulcer history etiology therapy MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Humans MeSH
- Keywords
- evoluce vědomí, psycho - fyzikální paralelismus, kotvy,
- MeSH
- Pain * enzymology psychology MeSH
- Taste physiology MeSH
- Smell physiology MeSH
- Hunger physiology MeSH
- Cognitive Science methods trends MeSH
- Humans MeSH
- Evolution, Molecular * MeSH
- Mutation physiology genetics MeSH
- Pleasure-Pain Principle MeSH
- Fishes MeSH
- Scyphozoa MeSH
- Fear physiology psychology MeSH
- Consciousness * physiology drug effects MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Keywords
- rytmický pohyb a jeho inhibice, redukce okrajových orgánů, kontraktilita,
- MeSH
- Invertebrates MeSH
- Animal Experimentation * MeSH
- Kymography methods utilization MeSH
- Motion * MeSH
- Scyphozoa * physiology growth & development drug effects MeSH
- Statistics as Topic MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
