Chyawanprash (CP) is an Ayurvedic health supplement which is made up of a super-concentrated blend of nutrient-rich herbs and minerals. It is meant to restore drained reserves of life force (ojas) and to preserve strength, stamina, and vitality, while stalling the course of aging. Chyawanprash is formulated by processing around 50 medicinal herbs and their extracts, including the prime ingredient, Amla (Indian gooseberry), which is the world's richest source of vitamin C. Chyawanprash preparation involves preparing a decoction of herbs, followed by dried extract preparation, subsequent mixture with honey, and addition of aromatic herb powders (namely clove, cardamom, and cinnamon) as standard. The finished product has a fruit jam-like consistency, and a sweet, sour, and spicy flavor. Scientific exploration of CP is warranted to understand its therapeutic efficacy. Scattered information exploring the therapeutic potential of CP is available, and there is a need to assemble it. Thus, an effort was made to compile the scattered information from ancient Ayurvedic texts and treatises, along with ethnobotanical, ethnopharmacological, and scientifically validated literature, that highlight the role of CP in therapeutics. Citations relevant to the topic were screened.

• MeSH
• funkční potraviny MeSH
• fytonutrienty analýza   MeSH
• lidé MeSH
• marketing MeSH
• potravní doplňky * MeSH
• rostlinné přípravky aplikace a dávkování   škodlivé účinky   farmakologie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• přehledy MeSH

• Klíčová slova
• biotechnologie - konference(Bangkok,1990) - sborníky prací, látky biologicky aktivní - sborníky prací,

• Konspekt
• Biologické vědy
• NLK Obory
• biologie
• biochemie
• chemie, klinická chemie

Chronic inflammation with a wide spectrum of connected diseases (e [...].

• MeSH
• fytonutrienty farmakologie   terapeutické užití   MeSH
• lidé MeSH
• objevování léků MeSH
• regulace genové exprese účinky léků   MeSH
• signální transdukce účinky léků   MeSH
• tradiční čínská medicína MeSH
• zánět farmakoterapie   metabolismus   MeSH
• zvířata MeSH
• Check Tag
• lidé MeSH
• zvířata MeSH
• Publikační typ
• úvodní články MeSH
• úvodníky MeSH

Ziziphora species represent the prototypical example of the Lamiaceae family. The phytochemicals present in Ziziphora include monoterpenic essential oils, triterpenes and phenolic substances belonging to the flavonoids. In Kazakh traditional medicine, Ziziphora species possess several medicinal uses. In particular, Z. bungeana Lam. and Z. clinopodioides Lam. are used for the treatment of illnesses related to the cardiovascular system or to combat different infections. Unfortunately, the majority of the information about the complex Ziziphora species is only available in Russian and Chinese language, therefore, we decided gather all available information on Kazakhstan Ziziphora, namely its content compounds, medicinal uses and published patents, to draw the attention of scientists to this very interesting plant with high medicinal potential.

• MeSH
• biologické přípravky chemie   izolace a purifikace   farmakologie   MeSH
• flavonoidy chemie   farmakologie   MeSH
• fytonutrienty chemie   izolace a purifikace   farmakologie   MeSH
• lidé MeSH
• oleje prchavé chemie   farmakologie   MeSH
• Rhizophoraceae chemie   MeSH
• zvířata MeSH
• Check Tag
• lidé MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH

Při chirurgickém léčení chronické osteomyelitidy použili autoři k výplni osteomyelitické dutiny bioaktivní sklokeramický materiál BAS-0 a BAS-HA u 20 nemocných od roku 1993. Uvedený sklokeramický materiál byl před operací nasycen roztokem antibiotik (Bykomycin, Likomycin). Současně byla podána antibiotika celkově. Pro daný účel je nejvýhodnější porézní forma uvedených materiálů. Kvůli nedostatku porézní sklokeramiky byla použita denzní se zdánlivou porozitou 15 % u 11 operovaných a kombinace jemné drti materiálu BAS-0 a BAS-HA a fibrinového lepidla Beriplast u 4 operovaných. Kontrolováno bylo 19 pacientů; nejlepší výsledek byl dosažen při použití porézního materiálu, kde všichni 4 pacienti se zhojili. Délka sledování je u nich 4 roky a 7 měsíců. Při použití denzního materiálu se zhojilo přes 50 % operovaných. Horší výsledek byl při použití kombinace BAS-0 a BAS-HA s Beriplastem. Byly provedeny 3 reoperace. Diskutovány jsou výhody a nevýhody použití uvedených materiálů v léčení osteomyelitických dutin a perspektivy do budoucna.

Since 1993 the authors have applied in the surgical treatment of chronic osteomyelitis bioactive glass-ceramic material BAS-0 and BAS-HA for filling the osteomyelitic cavity in 20 patients. Prior to the operation the glass-ceramic material was saturated with ATB solution (Bycomycin, Lycomycin). At the same time ATB were administered also in general. The most suitable for the given purpose is the porouš form of the mentioned materials. Due to the lack of porous glass-ceramics, dense material was used with 15 % apparent porosity in 11 patients and a combination of fine cullet of BAS-0 and BAS-HA and Beriplast fibrin glue in 4 patients. 19 patients were followed up, the best result was achieved in the application of porous material when ail 4 patients healed. The period of follow up in these patients is 4 years and 7 months. After the application of dense material more than 50 % of patients healed. A worse result was recorded in the application of the combination of BAS-0 and BAS-HA with Beriplast.Three reoperations were performed.The authors discuss the pros and cons of the application of the mentioned materials in the treatment of osteomyelitic cavities and their prospect for the future.

• MeSH
• antibakteriální látky terapeutické užití   MeSH
• biokompatibilní materiály MeSH
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• nosiče léků MeSH
• osteomyelitida diagnóza   chirurgie   MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• senioři MeSH
• Publikační typ
• kazuistiky MeSH
• přehledy MeSH

Cynomorium coccineum and Cynomorium songaricum are unusual parasitic plants in the family Cynomoriaceae characterized by their unusual appearance and way of life. Due to their special habit and extremely rare occurrence, in the past, various magical properties have been attributed to these plants. The plant Cynomorium coccineum, which is found in the Mediterranean, has been used in Europe since the Middle Ages in folk medicine under the name fungus maletensis (maltese fungus). It was used for the same purpose in Arabic cultures under the name tarthuth. The Asian species (Cynomorium songaricum), sometimes considered a subspecies of C. coccineum, is still used in traditional Chinese medicine under the name Suo Yang. Recent studies show that the plant has a number of beneficial effects on the body and there is a real possibility that the substances present in Suo Yang or substances derived therefrom will be used in the future for therapeutic purposes. Of particular interest are their effects on sexual function. Preclinical experiments in male rats showed an increase in fertility after administration of Cynomoriumextract. In these tests, an increase in the weight of the testes and an increase in the number of spermatozoa and their viability were observed. Cynomorium plants offer a new approach to the treatment of human infertility, which is currently a major problem.

• MeSH
• Cynomorium * MeSH
• farmakologické jevy MeSH
• fytonutrienty * farmakologie   terapeutické užití   MeSH
• krysa rodu rattus MeSH
• lidé MeSH
• mužská infertilita farmakoterapie   MeSH
• myši MeSH
• spermie účinky léků   MeSH
• tradiční lékařství MeSH
• Check Tag
• krysa rodu rattus MeSH
• lidé MeSH
• myši MeSH
• Publikační typ
• práce podpořená grantem MeSH
• přehledy MeSH

Mushroom poisoning has always been a threat to human health. There are a large number of reports about ingestion of poisonous mushrooms every year around the world. It attracts the attention of researchers, especially in the aspects of toxin composition, toxic mechanism and toxin application in poisonous mushroom. Inocybe is a large genus of mushrooms and contains toxic substances including muscarine, psilocybin, psilocin, aeruginascin, lectins and baeocystin. In order to prevent and remedy mushroom poisoning, it is significant to clarify the toxic effects and mechanisms of these bioactive substances. In this review article, we summarize the chemistry, most known toxic effects and mechanisms of major toxic substances in Inocybe mushrooms, especially muscarine, psilocybin and psilocin. Their available toxicity data (different species, different administration routes) published formerly are also summarized. In addition, the treatment and medical application of these toxic substances in Inocybe mushrooms are also discussed. We hope that this review will help understanding of the chemistry and toxicology of Inocybe mushrooms as well as the potential clinical application of its bioactive substances to benefit human beings.

• MeSH
• Agaricales chemie   metabolismus   fyziologie   MeSH
• lektiny chemie   farmakologie   MeSH
• lidé MeSH
• muskarin chemie   otrava   toxicita   MeSH
• organofosforové sloučeniny chemie   toxicita   MeSH
• otrava houbami etiologie   terapie   MeSH
• psilocybin analogy a deriváty   chemie   otrava   toxicita   MeSH
• tryptaminy chemie   toxicita   MeSH
• zvířata MeSH
• Check Tag
• lidé MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH

Berries, especially members of several families, such as Rosaceae (strawberry, raspberry, blackberry), and Ericaceae (blueberry, cranberry), belong to the best dietary sources of bioactive compounds (BAC). They have delicious taste and flavor, have economic importance, and because of the antioxidant properties of BAC, they are of great interest also for nutritionists and food technologists due to the opportunity to use BAC as functional foods ingredients. The bioactive compounds in berries contain mainly phenolic compounds (phenolic acids, flavonoids, such as anthocyanins and flavonols, and tannins) and ascorbic acid. These compounds, either individually or combined, are responsible for various health benefits of berries, such as prevention of inflammation disorders, cardiovascular diseases, or protective effects to lower the risk of various cancers. In this review bioactive compounds of commonly consumed berries are described, as well as the factors influencing their antioxidant capacity and their health benefits.

• MeSH
• anthokyaniny chemie   MeSH
• antioxidancia chemie   MeSH
• brusnice s jedlými plody chemie   MeSH
• Ericaceae chemie   MeSH
• fenoly chemie   MeSH
• flavonoidy chemie   MeSH
• jahodník chemie   MeSH
• kyselina askorbová chemie   MeSH
• ovoce MeSH
• Rosaceae chemie   MeSH
• Rubus chemie   MeSH
• Vaccinium macrocarpon chemie   MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• přehledy MeSH

• Klíčová slova
• houba, korálovec ježatý, protinádorová látka,
• MeSH
• Agaricales * chemie   MeSH
• antidepresiva MeSH
• gastrointestinální látky MeSH
• hypolipidemika MeSH
• imunologické faktory MeSH
• lidé MeSH
• neuroprotekce MeSH
• neuroprotektivní látky MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• práce podpořená grantem MeSH
• přehledy MeSH

• Publikační typ
• abstrakt z konference MeSH