activity-density
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We aimed at evaluating the relationship of fat mass and physical activity to bone mass in postmenopausal women. We invited 67 women from University of the Third Age (U3A) Palacky University in Olomouc. They underwent the measuring of body composition, bone density, intensity and volume of physical activity. Body composition and bone mineral density (BMD) measurements were performed using Dual-energy X-ray absorptiometry methodology (DXA) and bioelectrical impedance (InBody 720, Tanita BC-418). We use accelerometer ActiGraph GT1M for physical activity measurement. The mean age and weight were 63.15 ± 4.87 years and 71.17 ± 13.29 kilograms, respectively. Accordingly to the body mass index (BMI), 37.3 % were of normal weight, 35.8 % of the patients were overweight and 26.7 % were obese. Overweight or obese women had significantly higher bone mass. However, amount of daily steps (> 10 000) decrease fat mass. In addition, lower BMI is associated to lower BMC and BMD of total femur and possible heighten risk of osteoporotic fracture.
- MeSH
- Albers-Schönbergova nemoc diagnóza prevence a kontrola MeSH
- antropometrie metody MeSH
- financování organizované MeSH
- index tělesné hmotnosti MeSH
- interpretace statistických dat MeSH
- kostní denzita fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- metabolické nemoci kostí diagnóza prevence a kontrola MeSH
- postmenopauza fyziologie MeSH
- primární prevence metody statistika a číselné údaje MeSH
- senioři MeSH
- složení těla fyziologie MeSH
- techniky cvičení a pohybu metody statistika a číselné údaje využití MeSH
- tělesná hmotnost fyziologie MeSH
- tělesná konstituce fyziologie MeSH
- životní styl MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
Studies of the relationships between BMD, PA and body composition have shown variable results. Therefore, the aim of this cross-sectional study was to determine the relationships between accelerometer-determined PA and selected body composition parameters to total and regional BMD of the proximal femur in postmenopausal women. BMD and body composition were measured using dual energy X-ray absorptiometry in 97 women with a mean age 63.63±5.23 years. PA was monitored using an ActiGraph GT1M accelerometer. Correlation analysis did not show significant relationships between PA variables and BMD, but increases in body composition variables were associated with increases in BMD. Lean body mass was the strongest predictor of proximal femur BMD (r=0.18-0.37), explaining 10% of the variance for total femur, and 3-14% of the variance for regional femurs. Correlations increased when the analysis was controlled for age (r(p)=0.20-0.39). A significant relationship was also found between body fat mass and BMD (r=0.16-0.30; r(p)=0.25-0.37). Analysis of differences between women with normal BMD and osteopenic women showed statistically significant differences in age (p=0.003; η(2)=0.09) and lean body mass (p=0.048; η(2)=0.04). In conclusion, body composition is a stronger predictor of proximal femur BMD than PA variables. However, other studies are necessary to clarify the influence of long-term PA and exercise type on proximal femur BMD.
- MeSH
- absorpční fotometrie MeSH
- adipozita fyziologie MeSH
- kostní denzita fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- metabolické nemoci kostí epidemiologie patofyziologie MeSH
- pohybová aktivita fyziologie MeSH
- postmenopauza fyziologie MeSH
- prevalence MeSH
- průřezové studie MeSH
- senioři MeSH
- složení těla fyziologie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- MeSH
- Bacillus subtilis MeSH
- chemická precipitace MeSH
- chromatografie DEAE-celulózová MeSH
- deoxyribonukleasy MeSH
- DNA bakterií MeSH
- DNA MeSH
- fosfatasy MeSH
- kvartérní amoniové sloučeniny MeSH
- mikrobiální genetika MeSH
- RNA transferová MeSH
- sírany MeSH
- skot MeSH
- spektrofotometrie MeSH
- Streptococcus pneumoniae MeSH
- thymus MeSH
- transformace genetická MeSH
- tritium MeSH
- zvířata MeSH
- Check Tag
- skot MeSH
- zvířata MeSH
- MeSH
- acetylglukosaminidasa moč MeSH
- dítě MeSH
- kostní denzita MeSH
- ledvinové kanálky enzymologie MeSH
- lidé MeSH
- mladiství MeSH
- osteoporóza epidemiologie moč MeSH
- poruchy metabolismu vápníku epidemiologie moč MeSH
- poruchy růstu epidemiologie moč MeSH
- prevalence MeSH
- rizikové faktory MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
Beside biomaterials' bulk properties, their surface properties are equally important to control interfacial biocompatibility. However, due to the inadequate interaction with tissue, they may cause foreign body reaction. Moreover, surface induced thrombosis can occur when biomaterials are used for blood containing applications. Surface modification of the biomaterials can bring enhanced surface properties in biomedical applications. Sulfated polysaccharide coatings can be used to avoid surface induced thrombosis which may cause vascular occlusion (blocking the blood flow by blood clot), which results in serious health problems. Naturally occurring heparin is one of the sulfated polysaccharides most commonly used as an anticoagulant, but its long term usage causes hemorrhage. Marine sourced sulfated polysaccharide fucoidan is an alternative anticoagulant without the hemorrhage drawback. Heparin and fucoidan immobilization onto a low density polyethylene surface after functionalization by plasma has been studied. Surface energy was demonstrated by water contact angle test and chemical characterizations were carried out by Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. Surface morphology was monitored by scanning electron microscope and atomic force microscope. Finally, their anticoagulation activity was examined for prothrombin time (PT), activated partial thromboplastin time (aPTT), and thrombin time (TT).
- MeSH
- antikoagulancia škodlivé účinky chemie farmakologie MeSH
- heparin škodlivé účinky chemie farmakologie MeSH
- krev účinky léků MeSH
- lidé MeSH
- polyethylen chemie MeSH
- polysacharidy škodlivé účinky chemie farmakologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
