- MeSH
- Adult MeSH
- Research Support as Topic MeSH
- Humans MeSH
- Drug Monitoring methods MeSH
- Biomarkers, Tumor diagnostic use MeSH
- Breast Neoplasms diagnosis drug therapy pathology MeSH
- Oncogene Proteins analysis blood MeSH
- Predictive Value of Tests MeSH
- Antineoplastic Agents therapeutic use MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Female MeSH
Karcinom prostaty je jednou z hlavných příčin morbidity a mortality na zhubne nádory u mužov. Aj napriek pokrokom v jeho diagnostike a liečbe sa nezaznamenal výraznější pokles v úmrtnosti. Preto sa súčasné vědecké výskumy zameriavajú na Madame prognostických faktorov, ktoré by mohli predpovedať vývoj ochorenia pacientov. Mnoho klinicky významných prediktívnych faktorov karcinomu prostaty vychádza z vyšetrenia vzorky tkaniva patológom. Podlá Kolegia amerických patológov (CAP) sú prognostické a prediktívne faktory zatriedené do troch hlavných kategorií. Autor článku popisuje jednotlivé faktory v týchto skupinách. Zdórazňuje nutnost analyzovat a študovat ďalšie nové biomarkery za účelom lepšieho individuálneho managementu a liečby pacientov.
Prostatě cancer is a leading cause of morbidity and mortality in men. Despite advances in detection and tre¬atment, there has been no significant decrease in mortality. Therefore, recent research effort has gone into the finding of the prognostic factors that can predict outcome in patients. Many of the clinically important predictive factors in prostatě cancers are derived from a pathologisťs examination of tissue specimens. According to College of American Pathologists (CAP), prognostic and predictive factors are stratified into three main categories. The author of the article describes individual factors included in these groups. He stress necessity to study and analyse other new biomarkers for better management and treatment in indivi¬dual patients.
- MeSH
- Androgens MeSH
- Ki-67 Antigen MeSH
- Carcinoma diagnosis mortality pathology MeSH
- Humans MeSH
- Biomarkers, Tumor genetics classification blood MeSH
- Tumor Suppressor Protein p53 MeSH
- Prostatic Neoplasms complications mortality pathology MeSH
- Oncogenes MeSH
- Predictive Value of Tests MeSH
- Prognosis MeSH
- Prostate-Specific Antigen blood MeSH
- Check Tag
- Humans MeSH
- MeSH
- Adult MeSH
- Kidney etiology MeSH
- Middle Aged MeSH
- Humans MeSH
- Multiple Myeloma diagnosis MeSH
- Receptors, Interleukin diagnostic use MeSH
- Aged MeSH
- Tumor Necrosis Factors MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Comparative Study MeSH
- MeSH
- Autoantibodies immunology blood MeSH
- Adult MeSH
- Research Support as Topic MeSH
- Graves Disease diagnosis pathology therapy MeSH
- Humans MeSH
- Endocrine System Diseases pathology therapy MeSH
- Orbital Diseases diagnosis pathology therapy MeSH
- Predictive Value of Tests MeSH
- Iodine Radioisotopes MeSH
- Thyroidectomy MeSH
- Thyrotoxicosis pathology therapy MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
Současné léčebné algoritmy metastazujícího renálního karcinomu jsou postaveny na sekvenčním použití léků. Je proto vhodné mít k dispozici před zahájením léčby prognostické i prediktivní markery, tak aby mohl být zvolen správný lék pro konkrétního pacienta s konkrétním typem nádoru ledvin. O potenciálních biomarkerech pojednává následující článek.
Current treatment algorithms for metastatic renal cell carcinoma are based on the sequential use of drugs. It is therefore advisable to have prognostic and predictive markers available before starting treatment so that the right drug can be chosen for a particular patient with a particular type of kidney tumor. The following article discusses potential biomarkers.
- MeSH
- B7-H1 Antigen MeSH
- Interleukin-6 MeSH
- Carcinoma, Renal Cell * genetics blood pathology MeSH
- Quality of Life MeSH
- Humans MeSH
- Neoplasm Metastasis MeSH
- Biomarkers, Tumor MeSH
- Von Hippel-Lindau Tumor Suppressor Protein genetics MeSH
- Predictive Value of Tests MeSH
- Prognosis MeSH
- Tumor Burden MeSH
- Vascular Endothelial Growth Factors MeSH
- Check Tag
- Humans MeSH
- MeSH
- Anthropometry MeSH
- Child MeSH
- Adult MeSH
- Humans MeSH
- Adolescent MeSH
- Predictive Value of Tests MeSH
- Growth MeSH
- Body Height MeSH
- Age Factors MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Humans MeSH
- Adolescent MeSH
- Publication type
- Review MeSH
- Comparative Study MeSH
- MeSH
- Survival Analysis MeSH
- Research Support as Topic MeSH
- Financing, Organized MeSH
- Genes, erbB-2 genetics immunology MeSH
- Data Interpretation, Statistical MeSH
- Neoplasm Invasiveness diagnosis genetics pathology MeSH
- Humans MeSH
- Lymph Nodes anatomy & histology pathology growth & development MeSH
- Neoplasms by Histologic Type MeSH
- Breast Neoplasms diagnosis etiology therapy MeSH
- Prognosis MeSH
- Neoplasm Staging classification methods utilization MeSH
- Check Tag
- Humans MeSH
