• MeSH
• Anti-Bacterial Agents MeSH
• Humans MeSH
• Dogs injuries   MeSH
• Wounds and Injuries drug therapy   complications   mortality   MeSH
• Aged MeSH
• Sepsis microbiology   mortality   MeSH
• Staphylococcus aureus immunology   isolation & purification   MeSH
• Streptococcus pyogenes immunology   isolation & purification   MeSH
• Animals MeSH
• Check Tag
• Humans MeSH
• Dogs injuries   MeSH
• Aged MeSH
• Female MeSH
• Animals MeSH

We report a very rare case of Streptococcus canis native infective endocarditis in a 73-year-old woman living in close contact with her dog. Her echocardiography showed large calcifications in the mitral annulus, massive regurgitation below the posterior leaflet, and adjacent vegetation. Blood culture was positive for Streptococcus Lancefield group G. A coronary artery bypass and mitral valve replacement had to be done. Streptococcus canis was detected in a heart valve using a broad range PCR followed by 16S rRNA and confirmed by tuf gene sequencing, while tissue culture remained negative. The patient was not bitten by her dog nor did she have comorbidities or skin ulcers. She fully recovered.

• MeSH
• Endocarditis, Bacterial diagnosis   microbiology   pathology   surgery   MeSH
• DNA, Bacterial chemistry   genetics   MeSH
• Echocardiography MeSH
• Peptide Elongation Factor Tu genetics   MeSH
• Phylogeny MeSH
• Calcinosis diagnostic imaging   MeSH
• Coronary Artery Bypass MeSH
• Blood microbiology   MeSH
• Humans MeSH
• Mitral Valve diagnostic imaging   pathology   surgery   MeSH
• Polymerase Chain Reaction MeSH
• DNA, Ribosomal chemistry   genetics   MeSH
• RNA, Ribosomal, 16S genetics   MeSH
• Sequence Analysis, DNA MeSH
• Aged MeSH
• Cluster Analysis MeSH
• Streptococcus classification   isolation & purification   MeSH
• Streptococcal Infections diagnosis   microbiology   pathology   surgery   MeSH
• Check Tag
• Humans MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Case Reports MeSH

• MeSH
• Amputation, Surgical methods   nursing   adverse effects   MeSH
• Diagnosis, Differential MeSH
• Drug Therapy, Combination MeSH
• Bites and Stings surgery   complications   MeSH
• Humans MeSH
• Nursing Care methods   MeSH
• Dogs MeSH
• Aged MeSH
• Shock, Septic diagnosis   surgery   mortality   MeSH
• Staphylococcus aureus pathogenicity   MeSH
• Streptococcus pyogenes pathogenicity   MeSH
• Check Tag
• Humans MeSH
• Dogs MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Case Reports MeSH

• MeSH
• Immune Sera MeSH
• Blood Bactericidal Activity MeSH
• Phagocytosis MeSH
• Complement System Proteins MeSH
• Horses MeSH
• Rats MeSH
• Leukocytes immunology   MeSH
• Humans MeSH
• Microbial Sensitivity Tests MeSH
• Guinea Pigs MeSH
• Muramidase MeSH
• Opsonin Proteins MeSH
• Swine MeSH
• Dogs MeSH
• Streptococcus immunology   MeSH
• Animals MeSH
• Check Tag
• Rats MeSH
• Humans MeSH
• Guinea Pigs MeSH
• Dogs MeSH
• Animals MeSH

• MeSH
• Immune Sera MeSH
• Blood Bactericidal Activity MeSH
• Phagocytosis MeSH
• Complement System Proteins MeSH
• Horses MeSH
• Rats MeSH
• Leukocytes immunology   MeSH
• Humans MeSH
• Microbial Sensitivity Tests MeSH
• Guinea Pigs MeSH
• Muramidase MeSH
• Opsonin Proteins MeSH
• Swine MeSH
• Dogs MeSH
• Streptococcus immunology   MeSH
• Animals MeSH
• Check Tag
• Rats MeSH
• Humans MeSH
• Guinea Pigs MeSH
• Dogs MeSH
• Animals MeSH

Propolis acts primarily as a biocide against invasive bacteria and fungi in the hive, suggesting its potential for industrial applications. In food application, propolis is considered as a chemical preservative in meat products, extending shelf life of frozen meat and other food. The mechanism of action is still unclear due to the synergy of multiple compounds contained in propolis and due to parallel targeting of multiple pathways within each affected organism. Here, we examined the antimicrobial properties of dimethylsulfoxide (DMSO) Czech propolis extract. Until recently, DMSO was only rarely used in the propolis studies, although the other solvents tested (mostly ethanol) may significantly affect the observed inhibitory effects, notwithstanding the antimicrobial effects of ethanol itself. Here, we provide results of zone inhibition tests against Aspergillus fumigatus, Microsporum gypseum, Microsporum canis, Candida albicans, Escherichia coli, Staphylococcus aureus, Listeria monocytogenes, and Enterococcus faecalis. Although we determined inhibitory effects against all the microorganisms tested, the dose-dependent response curves were not similar to each other. While inhibitory effects against C. albicans or S. aureus were strictly dose-dependent, responses of M. gypseum and E. faecalis displayed plateau across the broad range of concentrations tested. Interestingly, response of E. coli revealed the double-peak dose-dependent curve, and responses of M. canis and L. monocytogenes decreased at the highest concentrations tested. Suggested is evaluation of DMSO propolis extracts in experimental treatment of human and veterinary infections, preferably in multitherapy with antibiotics.

• MeSH
• Anti-Infective Agents pharmacology   MeSH
• Aspergillus fumigatus drug effects   growth & development   MeSH
• Candida albicans drug effects   growth & development   MeSH
• Dimethyl Sulfoxide pharmacology   MeSH
• Enterococcus faecalis drug effects   growth & development   MeSH
• Escherichia coli drug effects   growth & development   MeSH
• Ethanol metabolism   MeSH
• Food Contamination prevention & control   MeSH
• Food Preservation methods   MeSH
• Listeria monocytogenes drug effects   growth & development   MeSH
• Microsporum drug effects   growth & development   MeSH
• Microbial Sensitivity Tests MeSH
• Food Microbiology MeSH
• Food Preservatives pharmacology   MeSH
• Propolis pharmacology   MeSH
• Plant Extracts pharmacology   MeSH
• Staphylococcus aureus drug effects   growth & development   MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH

BACKGROUND: Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen the European One Health antimicrobial resistance (AMR) surveillance approach. OBJECTIVES: To define the combinations of animal species/production types/age categories/bacterial species/specimens/antimicrobials to be monitored in EARS-Vet. METHODS: The EARS-Vet scope was defined by consensus between 26 European experts. Decisions were guided by a survey of the combinations that are relevant and feasible to monitor in diseased animals in 13 European countries (bottom-up approach). Experts also considered the One Health approach and the need for EARS-Vet to complement existing European AMR monitoring systems coordinated by the ECDC and the European Food Safety Authority (EFSA). RESULTS: EARS-Vet plans to monitor AMR in six animal species [cattle, swine, chickens (broilers and laying hens), turkeys, cats and dogs], for 11 bacterial species (Escherichia coli, Klebsiella pneumoniae, Mannheimia haemolytica, Pasteurella multocida, Actinobacillus pleuropneumoniae, Staphylococcus aureus, Staphylococcus pseudintermedius, Staphylococcus hyicus, Streptococcus uberis, Streptococcus dysgalactiae and Streptococcus suis). Relevant antimicrobials for their treatment were selected (e.g. tetracyclines) and complemented with antimicrobials of more specific public health interest (e.g. carbapenems). Molecular data detecting the presence of ESBLs, AmpC cephalosporinases and methicillin resistance shall be collected too. CONCLUSIONS: A preliminary EARS-Vet scope was defined, with the potential to fill important AMR monitoring gaps in the animal sector in Europe. It should be reviewed and expanded as the epidemiology of AMR changes, more countries participate and national monitoring capacities improve.

• MeSH
• Anti-Bacterial Agents pharmacology   MeSH
• Bacteria MeSH
• Drug Resistance, Bacterial MeSH
• Cats MeSH
• Chickens MeSH
• One Health * MeSH
• Swine MeSH
• Dogs MeSH
• Cattle MeSH
• Animals MeSH
• Check Tag
• Cats MeSH
• Dogs MeSH
• Cattle MeSH
• Female MeSH
• Animals MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH

• MeSH
• Bacteriology MeSH
• Microbiology MeSH
• Mycology MeSH
• Parasitology MeSH
• Virology MeSH
• Publication type
• Monograph MeSH

• Conspectus
• Mikrobiologie
• NML Fields
• mikrobiologie, lékařská mikrobiologie
• infekční lékařství

• MeSH
• Bacteriology MeSH
• Publication type
• Textbook MeSH

• Conspectus
• Mikrobiologie
• NML Fields
• bakteriologie

Vysokoškolská učebnice, která se zaměřuje na lékařskou mikrobiologii, zejména na diagnostiku.

• MeSH
• Clinical Medicine MeSH
• Microbiological Techniques MeSH
• Microbiology MeSH
• Parasitology MeSH

• Conspectus
• Učební osnovy. Vyučovací předměty. Učebnice
• Mikrobiologie
• NML Fields
• mikrobiologie, lékařská mikrobiologie
• NML Publication type
• kolektivní monografie
• učebnice vysokých škol