... of Gene Delivery Methods 3 -- Step 3: Regulation of Gene Expression 6 -- Potential Applications of Gene ... ... -- Gene Transfer In Vitro 15 -- Gene Transfer for In Vivo and In Vitro Applications 16 -- Recombinant ... ... Virus Vectors 19 -- Gene Replacement Therapy 25 -- Summary 25 -- Chapter 4 The First Human Gene Therapy ... ... Therapy to Cancer -- Hematopoietic Stem Cell Gene Marking and Therapy Protocols -- T-Lymphocyte Gene ... ... -- The In Situ Gene Alteration of Cancer Cells -- Other Potential Uses of Sensitivity Genes -- The Genetic ...

... Table of Contents -- Chapter 1 -- Gene Targeting 1 -- Wolf M. ... ... Waldman -- Chapter 3 -- Gene Targeting in Tripanosomatids 65 -- Angela K. ... ... Cruz -- Chapter 4 -- Gene Targeting in Plants 83 -- Remko Offringa and Paul Hooykaas -- Chapter 5 -- ... ... Gene Targeting in Mammalian Development and Physiology 123 -- Thomas Lufkin -- Chapter 6 -- Animal Models ... ... Zarling -- Chapter 8 -- Gene Targeting in Human Gene Therapy 211 -- Manuel A. Vega -- Index -- 231 ...