• MeSH
• Anticoagulants MeSH
• Administration, Oral MeSH
• Drug Therapy MeSH
• Atrial Fibrillation MeSH
• Publication type
• Practice Guideline MeSH

• Conspectus
• Patologie. Klinická medicína
• NML Fields
• kardiologie
• angiologie
• farmacie a farmakologie
• NML Publication type
• brožury

Authors plan to observe chosen hemostasis activation markers from arteria pulmonalis and peripheral vessels blood samples during catheter radiofrequencyablation. Aim is to contribute to clarification of mechanisms of prothrombotic state.

Autoři plánují sledovat vybrané markery aktivace hemostázy z krevního vzorku z arteria pulmonalis a periferní krve v průběhu katetrizační radiofrekvenční ablace s cílem přispět k objasnění patofyziologických mechanismů protrombotického stavu.

• MeSH
• Electrophysiology MeSH
• Blood Coagulation MeSH
• Hemostasis, Surgical MeSH
• Catheter Ablation MeSH
• Hemorrhage physiopathology   MeSH
• Arrhythmias, Cardiac MeSH
• Thromboembolism MeSH

• Conspectus
• Patologie. Klinická medicína
• NML Fields
• kardiologie
• angiologie
• NML Publication type
• závěrečné zprávy o řešení grantu IGA MZ ČR

• MeSH
• Action Potentials drug effects   MeSH
• Anti-Arrhythmia Agents * pharmacokinetics   classification   therapeutic use   MeSH
• Humans MeSH
• Check Tag
• Humans MeSH

• MeSH
• Defibrillators, Implantable * MeSH
• Pacemaker, Artificial * MeSH
• Humans MeSH
• Neoplasms * radiotherapy   MeSH
• Radiotherapy MeSH
• Check Tag
• Humans MeSH
• Publication type
• Practice Guideline MeSH

odborného stanoviska poskytuje rámcový přehled potenciálních poruch funkce kardiostimulátorů a kardioverterů-defibrilátorů v souvislosti s radioterapií a navrhuje metodický postup pro průběh celého procesu radioterapie u pacientů s implantovanými kardiostimulátory nebo kardiovertery-defibrilátory. Je určen pro radiační onkology, kardiology, arytmology, radiologické fyziky a techniky, biomedicínské techniky a inženýry, radiologické asistenty, zdravotní sestry a další zdravotnické pracovníky, kteří se podílejí na léčbě těchto pacientů

The summary of the consesus document provides the framework that analyzes the potential failure modes of implanted cardiac devices (implantable cardiac pacemakers and implantable cardioverter-defibrillators - cardiac implantable electronic devices) in context of radiotherapy procedures and proposes the methodology for patient management in every step of the entire radiotherapy process. The summary is intended for radiation oncologists, cardiologists, arrhythmologists, medical physicists, dosimetrists, clinical engineers and technicians, nurses and other health professionals, that partake in the treatment of patients with such devices.

• MeSH
• Patient Safety MeSH
• Defibrillators, Implantable * MeSH
• Pacemaker, Artificial * MeSH
• Humans MeSH
• Patient Care Management MeSH
• Radiotherapy * MeSH
• Check Tag
• Humans MeSH
• Publication type
• Practice Guideline MeSH

• MeSH
• Algorithms MeSH
• Anti-Arrhythmia Agents therapeutic use   MeSH
• Anticoagulants therapeutic use   MeSH
• Electric Countershock MeSH
• Atrial Fibrillation * diagnosis   epidemiology   classification   therapy   MeSH
• Cardiovascular Abnormalities MeSH
• Cardiovascular Diseases MeSH
• Humans MeSH
• Mass Screening MeSH
• Arrhythmias, Cardiac MeSH
• Check Tag
• Humans MeSH

BACKGROUND: We evaluated the feasibility and effectiveness of thoracoscopic and a staged surgical and transcatheter ablation technique to treat stand-alone atrial fibrillation (AF). METHODS: . Between 2009 and 2016, a cohort of 65 patients underwent bilateral totally thoracoscopic ablation of symptomatic paroxysmal AF (n=30; 46%), persistent AF (n=18; 28%) or long-standing persistent AF (n=17; 26%) followed by catheter ablation in case of AF recurrence. Surgical box lesion procedure included bilateral pulmonary vein and left atrial posterior wall ablation using irrigated bipolar radiofrequency with documentation of conduction block. RESULTS: There were no intra- or peri-operative ablation-related complications. There was no operative mortality, no myocardial infarction, and no stroke. Skin-to-skin procedure time was 120.5 ± 22.0 min and the postoperative average length of stay was 8.1 ± 3.0 days. At discharge, 60 patients (92%) were in sinus rhythm. Median follow-up time was 866 days (IQR, 612-1185 days). One-year success rate after surgical procedure was 78% (off antiarrhythmic drugs). Eleven patients (17%) underwent catheter re-ablation. Sixty (92%) patients were free of atrial fibrillation after hybrid ablation (on demand) at 1 year follow up after the last ablation. The success at 24-months was achieved in 96% (paroxysmal) and 78% (persistent) patients. At the last follow-up control, 69% patients discontinued oral anticoagulant therapy. CONCLUSIONS: . Combination of mini-invasive surgical and endocardial treatment (two-stage hybrid procedure) is a safe and effective method for the treatment of isolated (lone) AF. This procedure provided good midterm outcomes.

• MeSH
• Anti-Arrhythmia Agents therapeutic use   MeSH
• Operative Time MeSH
• Length of Stay statistics & numerical data   MeSH
• Electrocardiography, Ambulatory MeSH
• Atrial Fibrillation drug therapy   surgery   MeSH
• Kaplan-Meier Estimate MeSH
• Catheter Ablation methods   MeSH
• Middle Aged MeSH
• Humans MeSH
• Follow-Up Studies MeSH
• Critical Care statistics & numerical data   MeSH
• Feasibility Studies MeSH
• Thoracoscopy methods   MeSH
• Treatment Outcome MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Evaluation Study MeSH

• MeSH
• Anti-Arrhythmia Agents pharmacology   therapeutic use   MeSH
• Anticoagulants therapeutic use   MeSH
• Bradycardia diagnosis   etiology   therapy   MeSH
• Defibrillators, Implantable MeSH
• Atrial Fibrillation diagnosis   etiology   complications   therapy   MeSH
• Tachycardia, Ventricular diagnosis   physiopathology   therapy   MeSH
• Humans MeSH
• Arrhythmias, Cardiac * diagnosis   pathology   therapy   MeSH
• Syncope diagnosis   etiology   therapy   MeSH
• Tachycardia diagnosis   pathology   therapy   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

• MeSH
• Medication Adherence MeSH
• Anti-Arrhythmia Agents pharmacokinetics   MeSH
• Anticoagulants * pharmacokinetics   adverse effects   therapeutic use   MeSH
• Antithrombins pharmacokinetics   adverse effects   therapeutic use   MeSH
• Stroke prevention & control   therapy   MeSH
• Renal Insufficiency, Chronic complications   MeSH
• Electric Countershock methods   standards   MeSH
• Atrial Fibrillation * drug therapy   complications   blood   MeSH
• Factor Xa Inhibitors administration & dosage   pharmacokinetics   therapeutic use   MeSH
• International Normalized Ratio MeSH
• Myocardial Ischemia drug therapy   complications   MeSH
• Catheter Ablation methods   MeSH
• Hemorrhage chemically induced   prevention & control   therapy   MeSH
• Humans MeSH
• Neoplasms complications   MeSH
• Perioperative Care methods   MeSH
• Liver Failure complications   MeSH
• Aged MeSH
• Pregnancy MeSH
• Warfarin administration & dosage   therapeutic use   MeSH
• Check Tag
• Humans MeSH
• Aged MeSH
• Pregnancy MeSH
• Publication type
• Practice Guideline MeSH

Fibrilace síní je podceňovanou reverzibilní příčinou dysfunkce levé komory srdeční navzdory adekvátní kontrole tepové frekvence. Udržení sinusového rytmu katetrizační ablací vede ke zlepšení funkce komor a snižuje mortalitu a hospitalizace pro srdeční selhání. Tyto výsledky posledních studií zpochybňují dosud uznávaný názor, že preferovanou strategií léčby u pacientů s fibrilací síní a srdečním selháním je kontrola srdeční frekvence.

Atrial fibrillation is an underappreciated reversible cause of left ventricular systolic dysfunction despite adequate rate control. Therestoration of sinus rhythm with catheter ablation results in an improvement in the ventricular function and is associated withlower rates of death and hospital admission for heart failure. These outcomes challenge the current treatment paradigm that ratecontrol is the appropriate strategy in patients with atrial fibrillation and heart failure.

• MeSH
• Amiodarone therapeutic use   MeSH
• Ventricular Dysfunction, Left diagnosis   complications   therapy   MeSH
• Atrial Fibrillation * diagnosis   complications   therapy   MeSH
• Cardiac Care Facilities methods   organization & administration   utilization   MeSH
• Cardiomyopathies diagnosis   complications   therapy   MeSH
• Catheter Ablation * methods   trends   utilization   MeSH
• Humans MeSH
• Meta-Analysis as Topic MeSH
• Randomized Controlled Trials as Topic MeSH
• Heart Rate physiology   MeSH
• Heart Failure * diagnosis   complications   therapy   MeSH
• Statistics as Topic MeSH
• Check Tag
• Humans MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH
• Review MeSH