- Keywords
- GreenLight laser, symptomy dolních cest močových, PVP, LUTS, BPH, fotoselektivní vaporizace prostaty,
- MeSH
- Laser Therapy * methods instrumentation utilization MeSH
- Humans MeSH
- Postoperative Complications MeSH
- Statistics as Topic MeSH
- Urologic Surgical Procedures, Male * methods instrumentation utilization MeSH
- Treatment Outcome MeSH
- Outcome and Process Assessment, Health Care statistics & numerical data MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Publication type
- Comparative Study MeSH
Na základě nejnovějších pokroků v laserové technologii profesor Malek z Mayo Clinic vyvinul vysoce účinnou a snadno proveditelnou vaporizační techniku laserové prostatektomie (LP), známou jako fotoselektivní vaporizace prostaty (PVP). Tato technika užívá GreenLight 532 nm KTP (kalium-titanyl-fosfát) laser o vysokém výkonu 80 W a nověji také LBO (litium triborát - 120 W), který je aplikován transuretrálně vláknem s postranním vyzařováním prostřednictvím laserového cystoskopu malého kalibru, k odpaření obstrukční benigní hyperplazie prostaty (BHP), prudce a se zabezpečením hemostázy. Velký počet studií prokazuje, že pomocí PVP je prostata odpařena prakticky bez krvácení. Výkon vyžaduje pouze krátkodobé zavedení katétru (případně vůbec žádnou katetrizaci), je spojen s nízkou mírou morbidity a pooperačního dyskomfortu, umožňuje rychlou rekonvalescenci a dosahuje vynikajících a trvalých výsledků. Obrovská výhoda GreenLight PVP spočívá v jeho pozoruhodně bezpečné aplikaci u pacientů s vysokým rizikem, u nichž jsou přítomny významné komorbidity (ASA >/= 3) a poruchy koagulace. Díky tomu, že jsou její výhody uznávány po celém světě, se GreenLight PVP stala vedoucím uchazečem o post operační léčby obstrukční BPH.
Recent advances in laser technology have led to the development by Male at Mayo Clinic of a new highly effective and easily performed vaporization technique for laser prostatectomy (LP) known as photoselective vaporization of the prostate (PVP), utilizing high-power GreenLight 532 nm (potassium titanyl phosphate [KTP] laser at 80 W, or more recently, lithium triborate [LBO] laser at 120 W) delivered transurethrally by a side-firing fiber through a small-caliber laser cystoskope to vaporize obstructive benign prostatic hyperplasia (BPH) actuely and hemostatically. A growing numer of studies indicate that PVP is relatively bloodless and followed by typically short-term catheterization or no catheterization, little morbidity or postoperative discomfort, rapid recovery, and excellent and durable outcomes. Advantages of GreenLight PVP become even more apparent in its remarkably safe application in high-risk patiens with significant comorbidities (ASA ≥ 3) and coagulation defects. With its merits gaining worldwide recognition, GreenLight PVP has become the leading contestant in the field of surgical therapy for obstuctive BPH.
- MeSH
- Anesthesia, General methods utilization MeSH
- Cystoscopy utilization MeSH
- Hemostasis, Surgical methods instrumentation utilization MeSH
- Outcome Assessment, Health Care MeSH
- Prostatic Hyperplasia surgery therapy MeSH
- Laser Therapy methods instrumentation utilization MeSH
- Lasers history utilization MeSH
- Humans MeSH
- Evidence-Based Medicine trends MeSH
- Postoperative Care methods MeSH
- Prostatectomy methods trends utilization MeSH
- Anesthesia, Spinal methods utilization MeSH
- Urogenital Surgical Procedures methods utilization MeSH
- Check Tag
- Humans MeSH
European urology supplements, ISSN 1569-9056 vol. 7, no. 4, April 2008
362-392 s. : il., tab. ; 28 cm
- MeSH
- Prostatic Hyperplasia therapy MeSH
- Laser Therapy methods instrumentation trends MeSH
- Minimally Invasive Surgical Procedures methods instrumentation trends MeSH
- Publication type
- Collected Work MeSH
- Conspectus
- Patologie. Klinická medicína
- NML Fields
- urologie
BACKGROUND: To compare baseline characteristics and outcomes of patients undergoing GreenLight laser vaporization (GL) or transurethral resection of the prostate (TURP) in a real life setting. METHODS: In this prospective observational cohort, the Clinical Research Office of the Endourological Society (CROES) collected data of consecutive GL or TURP treated patients. Treatment involved one of three GL laser powers (80 W, 120 W or 180 W) based on availability in each participating centre, or TURP. Data on baseline characteristics as well as functional measures were collected at three time points: 6-12 weeks, 6, and 12months after surgery. Functional measures included urinary flow parameters, perceived prostate function (IPSS), perceived erectile function (IIEF-5) and complications. RESULTS: Seven hundred thirteen patients underwent GL, and 234 patients underwent TURP. Overall, patients treated with GL show higher BMI, IIEF and medication use, together with lower urinary function (voided volume, incontinence, urinary retention) at baseline. After the procedure, despite higher antibiotic and antimuscarinic use and shorter hospital stay, readmission rates, PVR, PSA were higher, but Qmax, and IIEF were lower in the GL group. The rate of post-operative complications was 10.3% and 5.2% for the TURP and GL group, respectively (P=0.006). CONCLUSIONS: We were unable to categorically state which procedure is superior. This observational study confirms that treatment decision for either TURP or GL is not based on patient characteristics.
- MeSH
- Prostatic Hyperplasia surgery MeSH
- Urinary Incontinence etiology MeSH
- Laser Therapy instrumentation methods MeSH
- Humans MeSH
- Prospective Studies MeSH
- Aged MeSH
- Transurethral Resection of Prostate instrumentation methods MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Aged MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Observational Study MeSH
- Comparative Study MeSH
OBJECTIVES: To assess the feasibility of partial nephrectomy (PN) without renal hilar clamping using the 80-W GreenLight (532 nm) laser with opening of the collecting system followed by its suture in a porcine model.
- MeSH
- Financing, Organized MeSH
- Hemostatic Techniques MeSH
- Risk Assessment MeSH
- Immunohistochemistry MeSH
- Biopsy, Needle MeSH
- Constriction MeSH
- Blood Loss, Surgical prevention & control MeSH
- Laser Therapy methods MeSH
- Lasers MeSH
- Kidney Pelvis physiology surgery MeSH
- Disease Models, Animal MeSH
- Nephrectomy methods instrumentation MeSH
- Recovery of Function MeSH
- Swine MeSH
- Kidney Tubules, Collecting surgery pathology MeSH
- Sensitivity and Specificity MeSH
- Suture Techniques MeSH
- Feasibility Studies MeSH
- Sus scrofa MeSH
- Kidney Function Tests MeSH
- Treatment Outcome MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
V případě indikace aktivní léčby urolitiázy je v dnešní době vedle extrakorporální litotripse (ESWL) jednoznačně preferována minimálně invazivní endoskopická intervence s možností aktivního odstranění konkrementu včetně jeho případné desintegrace. Laserová technologie je efektivnější a bezpečnější než klasické alternativy litotripse (balistická, ultrazvuková a elektrohydraulická). V současné době se k endoskopické laserové fragmentaci používají pevnolátkové lasery na bázi Yttrium-Aluminium-Garnetového (YAG) krystalu s příměsí prvků ze skupiny Lanthanoidů (Nd, Ho). Z komerčně dostupných přístrojů vykazuje nejvyšší efektivitu Ho: YAG laser. Perspektivní se jeví aplikace Tm: YAG a Er: YAG laseru, případně jejich kombinace s předešlými. Autoři v článku přinášejí přehled aktuálních možností laserové litotripse v urologii a souhrn předběžných výsledků při použití nových aplikací.
Endoscopic stone removal including lithotripsy and the extracorporeal shock-wave lithotripsy are important parts of the stone disease treatment. As far as the devices for desintegration are concerned, the laser lithotripsy is superior to the common procedures such as ballistic, ultrasonic and electrohydraulic lithotripsy. In practice, the laser devices containing the solid lasing medium of the lanhtanoiddoped Yttrium-Aluminium-Garnet (YAG) crystal (especially Ho: YAG and Nd: YAG) are currently the only lasers used in this field. Among these, the Ho: YAG laser represents the most effective and universal solution. Both the Tm: YAG and Er: YAG lasers or a combination of one of them and one of the above mentioned are somewhat recent addition. The article presents the list of current possibilities of laser lithotripsy and the summary of preliminary results of new methods used.
Holmium laser zaujímá stabilní místo v rámci léčby celé řady urologických onemocnění. V uplynulých deseti letech byla tato modalita hojně užívána při léčbě benigní hyperplazie prostaty (BPH) a řada studií potvrzuje, že holmium laser představuje účinnou alternativu k dalším transuretrálním metodám léčby BPH i otevřené operaci. Autoři tohoto přehledu popisují současné chirurgické techniky využívající holmium laser a hodnotí nejnovější publikace srovnávající modality na bázi holmium laseru s tradičními transuretrálními technikami, se zaměřením zejména na enukleaci prostaty pomocí holmium laseru (HoLEP). Nejnovější studie prokazují krátko- i dlouhodobou účinnost HoLEP i dalších modalit na bázi holmium laseru, a poskytují tak důkazy pro jejich častější využití v rámci léčby benigní obstrukce. Transuretrální operace s využitím holmium laseru je účinnou metodou léčby BPH, jež poskytuje vynikající a trvalé funkční výsledky a ve srovnání s běžnými transuretrálními technikami je spojena s minimální krátko- i dlouhodobou morbiditou.
The holmium laser is a well-established instrument in the treatment of a variety of urologic conditions. Treatment of benign prostatic hyperplasia (BPH) with the holmium laser has grown steadily over the last decade, with multiple studies demonstrating its role as an effective alternative to other transurethral and open surgicaltreatments for BPH. This review describes current surgical techniques that employ the holmium laser and surveys recent literature comparing holmium-based treatments to traditional transurethral techniques, with particular attention to holmium laser enucleation of the prostate (HoLEP). Recent studies continue to support the short and long-term efficacy of HoLEP and other holmium-based treatments, providing evidence for the laser’s growing use in the treatment of benign obstruction. Transurethral surgery with the holmium laser endures as an effectual treatment for BPH that offers excellent, lasting functional outcomes with favorable short and long-term morbidity when compared with conventional transurethral techniques.
- Keywords
- benigní hyperplazie prostaty,
- MeSH
- Holmium MeSH
- Prostatic Hyperplasia * surgery MeSH
- Clinical Competence MeSH
- Learning Curve MeSH
- Laser Therapy * methods MeSH
- Lasers, Solid-State * adverse effects therapeutic use MeSH
- Humans MeSH
- Postoperative Complications MeSH
- Prostatectomy methods MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Publication type
- Review MeSH
PURPOSE OF REVIEW: To discuss the most recent surgical lasers that have been made available to us and to evaluate their potential in performing en bloc resection of nonmuscle invasive bladder cancer. RECENT FINDINGS: Laser en bloc resection of bladder tumors (ERBT) can be performed with a number of laser systems including Ho:YAG, GreenLight, diode, Tm:YAG and thulium fiber lasers (TFL). The data that is currently available suggests that the water-targeting devices (utilizing water as a primary chromophore - Ho:YAG, Tm:YAG, TFL) may have a number of advantages over hemoglobin-targeting systems (potassium titanyl phosphate:YAG, lithium triborate:YAG). One recent addition to the surgical armamentarium Moses effect enhanced Ho:YAG and the TFL (being able to work both in quasi-continuous and SuperPulsed modes) necessitates careful discussion and comparison with the other available devices. SUMMARY: The majority of available lasers have proven to be safe to use and compared to electrocautery allow for lower rates of obturator nerve reflex and result in fewer bleeding complications. The minimal penetration depth and decreased peak power of Tm:YAG and TFLs render them the devices of choice when it comes to ERBT. Unfortunately, more studies on ERBT with TFL are needed in order for us to make a sound assessment of the respective pros and cons.
- MeSH
- Lithotripsy, Laser * MeSH
- Lasers, Solid-State * adverse effects MeSH
- Humans MeSH
- Urinary Bladder Neoplasms * pathology surgery MeSH
- Thulium MeSH
- Water MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- MeSH
- Lasers, Solid-State therapeutic use MeSH
- Middle Aged MeSH
- Humans MeSH
- Retinal Artery Occlusion pathology surgery MeSH
- Aged MeSH
- Embolization, Therapeutic methods MeSH
- Thrombolytic Therapy methods MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Letter MeSH
- Case Reports MeSH
Chirurgická terapie laserem v otorinolaryngologii je využívána již desítky let. Různé typy laserů mají odlišné vlastnosti a možnosti použití. Thulium laser v sobě kombinuje účinky kvalitního řezu, dobré hemostázy a mělkého průniku do tkání. Jeho použití je možné i pro minimálně invazivní chirurgické výkony v dětské otorinolaryngologii. Retrospektivně byl hodnocen soubor 34 pacientů ve stáří od 5 dní do 19 let, operovaných technikou Thulium laseru na KDORL FN Brno a LF MU v období od 05/12 do 11/13. Z tohoto souboru 16 pacientů podstoupilo operační výkon v oblasti nosu, kde bylo nejčastějším výkonem chirurgické řešení vrozené choanální atrézie - 5 případů. Druhým nejvíce zastoupeným výkonem bylo chirurgické ošetření neprůchodnosti slzných cest - 10 pacientů podstoupilo dakryocystorinostomii. Z naší studie vyplývá, že tato metoda má mnohostranné využití a je bezpečná i u nejmenších dětí. KLÍČOVÁ SLOVA: Thulium laser, laserové operace v otorinolaryngologii, dětský věk
Laser surgery in otorhinolaryngology has been used for decades. Various types of laser devices differ in properties and application. Thulium laser combines fine incision, good hemostasis and shallow tissue penetration. For these reasons it can be used for minimum invasive surgeries in pediatric otorhinolaryngology. We retrospectively evaluated a sample of 34 patients aged between 5 days and 19 years, who underwent Thulium laser surgery at Clinic of Pediatric ENT of the University Hospital Brno and Faculty of Medicine of Masaryk University from December 2012 to November 2013. 16 patients of this sample underwent nasal surgery. Surgery of congenital choanal atresia was the most frequent in this area (5 cases). Second most frequent surgery was a treatment of lacrimal apparatus obstruction – 10 patients underwent dacryocystorhinostomy. We conclude that Thulium laser technique has a wide-ranging possibility of application and is safe even in the youngest children.
- MeSH
- Choanal Atresia surgery MeSH
- Dacryocystorhinostomy methods statistics & numerical data MeSH
- Child MeSH
- Infant MeSH
- Laser Therapy * methods instrumentation statistics & numerical data MeSH
- Lasers, Solid-State MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Infant, Newborn MeSH
- Lacrimal Duct Obstruction MeSH
- Otorhinolaryngologic Diseases * surgery MeSH
- Child, Preschool MeSH
- Retrospective Studies MeSH
- Thulium * MeSH
- Check Tag
- Child MeSH
- Infant MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Male MeSH
- Infant, Newborn MeSH
- Child, Preschool MeSH
- Female MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH