Testing
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BACKGROUND: Antifungal drug resistance in dermatophytes was first reported shortly after the turn of the millennium and has today been reported in Trichophyton and occasionally in Microsporum, but not in Epidermophyton species. Although drug resistance in dermatophytes is not routinely investigated, resistance in Trichophyton spp. is increasingly reported worldwide. The highest rates are observed in India (36% and 68% for terbinafine (MIC ≥4 mg/L) and fluconazole (MICs ≥16 mg/L), respectively), and apparently involve the spread of a unique clade related to the Trichophyton mentagrophytes/Trichophyton interdigitale complex. OBJECTIVES: The European Committee on Antimicrobial Susceptibility Testing Subcommittee on Antifungal Susceptibility Testing (EUCAST-AFST) has released a new method (E.Def 11.0) for antifungal susceptibility testing against microconidia-forming dermatophytes including tentative MIC ranges for quality control strains and tentative breakpoints against Trichophyton rubrum and T. interdigitale. Here, the details of the new procedure E.Def 11.0 are described. SOURCES: This technical note is based on the multicentre validation of the EUCAST dermatophyte antifungal susceptibility testing method, the mould testing method (E.Def 9.3.2) and the updated quality control tables for antifungal susceptibility testing document, v 5.0 (available on the EUCAST website). CONTENTS: The method is based on the EUCAST microdilution method for moulds but significant differences include: (a) an altered test medium selective for dermatophytes; (b) an altered incubation time and temperature; and (c) a different end-point criterion (spectrophotometric determination) of fungal growth. It can easily be implemented in laboratories already performing EUCAST microdilution methods and has been validated for terbinafine, voriconazole, itraconazole and amorolfine against T. rubrum and T. interdigitale. IMPLICATIONS: This standardized procedure with automated end-point reading will allow broader implementation of susceptibility testing of dermatophytes and so facilitate earlier appropriate therapy. This is important, as resistance is rapidly emerging and largely underdiagnosed.
Introduction: Current modern trend of health care leads to acceleration of diagnostic and therapeutic processes. One of the ways of acceleration is using the methods of Point of care testing (hereafter POCT), which have to be used correctly so that they brought valid results of testing. Similarly, as such, they enable appropriate therapeutic processes. The article addresses effective implementation of POCT methods to clinical practice, specifically modern glucometer named ACCU-CHEK Inform. This glucometer was designed specifically for hospital use. The aim: The aim of research was to evaluate declared way of implementation of glucometer ACCU-CHEK Inform to clinical practice and main determinates of successful use. Metodhology: Questionnaire´s survey was realized among 194 final users of glucometer ACCU-CHEK Inform at the Faculty Hospital Brno. Results and Discusion: It was found out that the form of training (choice of instructor and didactic methods of training) significantly influence subjective evaluation of respondents´ knowledge about using ACCU-CHEK Inform glucometer. Conclusion: Process of implementation of the new diagnostic and therapeutic procedure has to contain every accessible methods and processes for effective use of the new technology. Mainly, it has to be exact and routine procedure oriented.
- Klíčová slova
- glukometr,
- MeSH
- doškolování metody organizace a řízení pracovní síly MeSH
- hodnocení postupů (zdravotní péče) MeSH
- krevní glukóza analýza MeSH
- lidé MeSH
- odběr vzorku krve * přístrojové vybavení MeSH
- průzkumy a dotazníky MeSH
- rozšiřování inovací * MeSH
- školitelé MeSH
- statistika jako téma MeSH
- vyšetření u lůžka * MeSH
- vzdělávání - programy sebehodnocení statistika a číselné údaje MeSH
- zdravotní sestry v klinické praxi výchova MeSH
- znalosti MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- hodnotící studie MeSH
Rehabilitácia, ISSN 0375-0922 roč. VI, suppl. 7, 1973
128 s. : tab., grafy ; 24 cm
- MeSH
- diagnostické techniky kardiovaskulární MeSH
- kardiovaskulární nemoci MeSH
- rehabilitace MeSH
- zátěžový test MeSH
- Publikační typ
- kongresy MeSH
- MeSH
- diabetes mellitus 2. typu diagnóza MeSH
- glykovaný hemoglobin * analýza MeSH
- lidé MeSH
- point of care testing statistika a číselné údaje MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- novinové články MeSH
Journal of antimicrobial chemotherapy, ISSN 0305-7453 Vol. 48, suppl. S1, July 2001
v, 102 s. : il., tab. ; 28 cm
- MeSH
- antibiotická rezistence MeSH
- mikrobiální testy citlivosti MeSH
- Publikační typ
- sborníky MeSH
- Konspekt
- Mikrobiologie
- NLK Obory
- mikrobiologie, lékařská mikrobiologie
- farmacie a farmakologie
Annals of allergy, asthma & immunology, ISSN 1081-1206 vol. 100, no. 3, suppl. 3, 2008
148 s. : tab. ; 28 cm
sv.
- MeSH
- soudní vědy MeSH
- Publikační typ
- periodika MeSH
- Konspekt
- Lékařské vědy. Lékařství
- NLK Obory
- soudní lékařství
... Historical Paths to Modem Test Theory 14 -- 3. Groundwork for Item Response Theory 17 -- 4. ... ... Computerized Adaptive Testing (CAT): Historical and Conceptual Origins 44 -- 6. ... ... Testing Algorithms in Unidimensional IRT-based CAT 51 -- 6.1 Starting 53 -- 6.2 Continuing 54 -- 6.3 ... ... 62 -- 6.5 Evaluation of item selection and trait estimation methods used in computerized adaptive testing ... ... - R code used for the simulation of the PSDQ CAT 122 -- Appendix C - Test information and corresponding ...
1. elektronické vydání 1 online zdroj (134 stran)
- Klíčová slova
- Ostatní lékařské obory,
- MeSH
- interpretace statistických dat MeSH
- počítačová simulace MeSH
- průzkumy a dotazníky MeSH
- psychometrie MeSH
- NLK Obory
- statistika, zdravotnická statistika
