- MeSH
- Child MeSH
- Adult MeSH
- Helicobacter pylori MeSH
- Helicobacter Infections epidemiology transmission MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Family MeSH
- Antibody Specificity drug effects MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Female MeSH
- MeSH
- Alzheimer Disease MeSH
- Slow Virus Diseases MeSH
- Brain Diseases MeSH
- Publication type
- Case Reports MeSH
American journal of epidemiology ; Supplement Vol. 132. 1
202 s. : obr., tab., přeruš.bibliogr.
Autori sa v príspevku zaoberajú problematikou klasifikácie skupín atletických disciplín ovplyvňuj-úcich športovú výkonnosť sedemboja žien. Na identifikáciu skupín boli využité ukazovatele najlepšíchsvetových výkonov sedemboja nad 6200 bodov podľa dostupných údajov z IAAF (N = 172). Z klasifi-kačných metód zhlukovania boli použité hierarchické modely ako Average linkage (Between & Within- group), Single Linkage - Nearest neigbor, Complete Linkage - Farthest neigbor, Centroid linkage,Median clustering, Ward ́s method.Všetkých sedem zhlukových metód sa zhodlo v dvoch skupinách zhlukov a v obsahu disciplínv 2. klastry [200 m, skok od diaľky, 800 m, 100 m prekážok, skok do výšky] [vrh guľou, hod oštepom].Test stability so štruktúrou zhlukov sedemboja na úrovni 2. klastra je 100 %. Najvyššiu stabilitu42,86 % javí vnútorná hierarchia disciplín [200 m, Skok do diaľky, 100 m prekážok, Skok do výšky,800 m] [Vrh guľou, Hod oštepom].Hierarchické modely umožnili identifikovať skupiny atletických disciplíny ovplyvňujúce športovývýkon v sedemboji žien. Poznanie štruktúry športového výkonu prispieva k zefektívneniu tréningovéhoprocesu a určeniu viacbojárskej typológie pretekárok svetovej výkonnosti.
Authors deals with the problematics of group classification of athletics disciplines, which influence thesports performance in the women's heptathlon. For the group identification, the indicators of the bestworld's performance in heptathlon above the 6200 points according to the data from IAAF (N = 172)were used. From the classification methods of clustering the hierarchical models as the Average linkage(Between & Within-group), Single Linkage - Nearest neighbor, Complete Linkage - Farthest neighbor,Centroid linkage, Median clustering, and Ward ́s method were used.All seven clustering methods agreed in two groups of clusters and in the content of disciplines in2 clusters [200 meters, Long jump, 800 meters, 100 meters hurdles, High jump] [Shot put, Javelinthrow]. The stability test with the cluster structure of heptathlon in the level of the second cluster is100 %. The highest stability, 42,86 %, shows the internal hierarchy of disciplines [200 meters, Longjump, 100 meters hurdles, High jump, 800 meters] [Shot put, Javelin throw].Hierarchical models allow identifying groups of athletics disciplines that influence the sports perfor-mance in women's heptathlon. Understanding the structure of sports performance contributes to thestreamlining the training process and determining the combined events typology of world performanceathletes.
- MeSH
- Classification MeSH
- Track and Field classification MeSH
- Humans MeSH
- Sports classification MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Publication type
- Comparative Study MeSH
The availability of a great range of prior biological knowledge about the roles and functions of genes and gene-gene interactions allows us to simplify the analysis of gene expression data to make it more robust, compact, and interpretable. Here, we objectively analyze the applicability of functional clustering for the identification of groups of functionally related genes. The analysis is performed in terms of gene expression classification and uses predictive accuracy as an unbiased performance measure. Features of biological samples that originally corresponded to genes are replaced by features that correspond to the centroids of the gene clusters and are then used for classifier learning. Using 10 benchmark data sets, we demonstrate that functional clustering significantly outperforms random clustering without biological relevance. We also show that functional clustering performs comparably to gene expression clustering, which groups genes according to the similarity of their expression profiles. Finally, the suitability of functional clustering as a feature extraction technique is evaluated and discussed.
Markov Random Walks (MRW) has proven to be an effective way to understand spectral clustering and embedding. However, due to less global structural measure, conventional MRW (e.g., the Gaussian kernel MRW) cannot be applied to handle data points drawn from a mixture of subspaces. In this paper, we introduce a regularized MRW learning model, using a low-rank penalty to constrain the global subspace structure, for subspace clustering and estimation. In our framework, both the local pairwise similarity and the global subspace structure can be learnt from the transition probabilities of MRW. We prove that under some suitable conditions, our proposed local/global criteria can exactly capture the multiple subspace structure and learn a low-dimensional embedding for the data, in which giving the true segmentation of subspaces. To improve robustness in real situations, we also propose an extension of the MRW learning model based on integrating transition matrix learning and error correction in a unified framework. Experimental results on both synthetic data and real applications demonstrate that our proposed MRW learning model and its robust extension outperform the state-of-the-art subspace clustering methods.
- MeSH
- Algorithms MeSH
- Emotions physiology MeSH
- Humans MeSH
- Limbic System physiology MeSH
- Models, Neurological MeSH
- Neural Networks, Computer * MeSH
- Pattern Recognition, Automated methods MeSH
- Cluster Analysis MeSH
- Models, Theoretical MeSH
- Learning MeSH
- Artificial Intelligence MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Analysis of population genetic structure has become a standard approach in population genetics. In polyploid complexes, clustering analyses can elucidate the origin of polyploid populations and patterns of admixture between different cytotypes. However, combining diploid and polyploid data can theoretically lead to biased inference with (artefactual) clustering by ploidy. We used simulated mixed-ploidy (diploid-autotetraploid) data to systematically compare the performance of k-means clustering and the model-based clustering methods implemented in STRUCTURE, ADMIXTURE, FASTSTRUCTURE and INSTRUCT under different scenarios of differentiation and with different marker types. Under scenarios of strong population differentiation, the tested applications performed equally well. However, when population differentiation was weak, STRUCTURE was the only method that allowed unbiased inference with markers with limited genotypic information (co-dominant markers with unknown dosage or dominant markers). Still, since STRUCTURE was comparatively slow, the much faster but less powerful FASTSTRUCTURE provides a reasonable alternative for large datasets. Finally, although bias makes k-means clustering unsuitable for markers with incomplete genotype information, for large numbers of loci (>1000) with known dosage k-means clustering was superior to FASTSTRUCTURE in terms of power and speed. We conclude that STRUCTURE is the most robust method for the analysis of genetic structure in mixed-ploidy populations, although alternative methods should be considered under some specific conditions.
- MeSH
- Diploidy MeSH
- Genetic Variation genetics MeSH
- Genetic Markers genetics MeSH
- Genotype MeSH
- Polymorphism, Single Nucleotide genetics MeSH
- Microsatellite Repeats genetics MeSH
- Ploidies * MeSH
- Genetics, Population statistics & numerical data MeSH
- Cluster Analysis MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
