• MeSH
• kapitalismus MeSH
• náboženství a lékařství MeSH
• sebevražda psychologie   MeSH
• statistika jako téma MeSH
• střelné rány mortalita   MeSH
• Geografické názvy
• historické zeměpisné názvy MeSH

• Klíčová slova
• TIANEPTIN,
• MeSH
• antidepresiva aplikace a dávkování   farmakologie   terapeutické užití   MeSH
• depresivní poruchy farmakoterapie   MeSH
• Publikační typ
• multicentrická studie MeSH
• Geografické názvy
• Česká republika MeSH
• Slovenská republika MeSH

• MeSH
• cirkumcize u mužů MeSH
• HIV infekce prevence a kontrola   MeSH
• prevalence MeSH
• Check Tag
• mužské pohlaví MeSH
• Publikační typ
• zprávy MeSH

• Konspekt
• Veřejné zdraví a hygiena
• NLK Obory
• andrologie
• urologie
• veřejné zdravotnictví
• NLK Publikační typ
• publikace WHO

• MeSH
• antiflogistika nesteroidní terapeutické užití   MeSH
• hyperplazie prostaty farmakoterapie   patofyziologie   MeSH
• lidé MeSH
• mastné alkoholy terapeutické užití   MeSH
• pacientův souhlas se zdravotní péčí statistika a číselné údaje   MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH

Pygeum africanum extract is available as Tadenan in many countries, including those in central and eastern Europe, for the treatment of mild to moderate BPH. Its efficacy and acceptability have been demonstrated in numerous open and placebo-controlled studies in large populations. The present open three-centre efficacy and safety study was conducted according to common protocol at urology clinics in the Czech and Slovak Republics and in Poland, in order to confirm the therapeutic profile of Pygeum africanum in conditions of daily practice, using International Prostate Symptom Score (IPSS) and flowmetry assessments. Men aged 50-75 years and in compliance with the selection criteria (including IPSS > or = 12, quality of life (QoL) score > or = 3, and maximum urinary flow < or = 15 ml/s) were first examined then recalled after two weeks during which no treatment was provided (washout and check of stability). If still compliant, they were entered at this point into a two-month period of treatment with Pygeum africanum extract 50 mg twice daily. There followed a further one-month period without treatment, the objective being to evaluate the persistence of any effects observed during the previous two months of Pygeum africanum administration. The primary efficacy parameter investigated was IPSS; the other efficacy parameters were QoL, nocturnal frequency, maximum urinary flow, average urinary flow, post-voiding residual volume and prostatic volume, after one and two months of Pygeum africanum treatment and one month after stopping treatment. A total of 85 patients were evenly distributed between the three centres and completed the entire study. At inclusion their mean IPSS was 16.17, QoL was 3.60 and nocturia was 2.6 times per night. The changes in subjective scores, IPSS and QoL after the two-month treatment period were highly statistically significant with mean improvements of 40% and 31%, respectively. Nocturnal frequency was reduced by 32% and the mean reduction was again highly statistically significant. Mean maximum urinary flow, average urinary flow and urine volume were also statistically significantly improved, but the modest improvement in post-voiding volume did not reach statistical significance. The improvements, which exceeded those observed with placebo in earlier studies, were maintained after one month without treatment indicating an interesting persistence of clinically useful activity. Prostatic volume and quality of sexual life remained unchanged throughout. No treatment-related adverse effects were observed. In conclusion, under conditions of daily practice, Pygeum africanum extract induces significant improvement in IPSS and uroflowmetry parameters. These positive effects are accompanied by a very satisfactory safety profile with the overall result of a substantial improvement in QoL.

• MeSH
• antiflogistika nesteroidní terapeutické užití   MeSH
• hyperplazie prostaty farmakoterapie   patofyziologie   psychologie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mastné alkoholy terapeutické užití   MeSH
• pacientův souhlas se zdravotní péčí statistika a číselné údaje   MeSH
• rostlinné extrakty MeSH
• senioři MeSH
• stupeň závažnosti nemoci MeSH
• urodynamika účinky léků   MeSH
• výsledek terapie MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• Publikační typ
• časopisecké články MeSH
• klinické zkoušky MeSH
• multicentrická studie MeSH
• Geografické názvy
• Česká republika MeSH
• Polsko MeSH
• Slovenská republika MeSH

BACKGROUND: Innovative uses of mobile health (mHealth) technology for real-time measurement and management of epilepsy may improve the care provided to patients. For instance, seizure detection and quantifying related problems will have an impact on quality of life and improve clinical management for people experiencing frequent and uncontrolled seizures. Engaging patients with mHealth technology is essential, but little is known about patient perspectives on their acceptability. The aim of this study was to conduct an in-depth qualitative analysis of what people with uncontrolled epilepsy think could be the potential uses of mHealth technology and to identify early potential barriers and facilitators to engagement in three European countries. METHOD: Twenty people currently experiencing epileptic seizures took part in five focus groups held across the UK, Italy, and Spain. Participants all completed written consent and a demographic questionnaire prior to the focus group commencing, and each group discussion lasted 60-120 min. A coding frame, developed from a systematic review of the previous literature, was used to structure a thematic analysis. We extracted themes and subthemes from the discussions, focusing first on possible uses of mHealth and then the barriers and facilitators to engagement. RESULTS: Participants were interested in mHealth technology as a clinical detection tool, e.g., to aid communication about seizure occurrence with their doctors. Other suggested uses included being able to predict or prevent seizures, and to improve self-management. Key facilitators to engagement were the ability to raise awareness, plan activities better, and improve safety. Key barriers were the potential for increased stigma and anxiety. Using familiar and customizable products could be important moderators of engagement. CONCLUSION: People with uncontrolled epilepsy think that there is a scope for mHealth technology to be useful in healthcare as a detection or prediction tool. The costs will be compared with the benefits when it comes to engagement, and ongoing work with patients and other stakeholders is needed to design practical resources.

• MeSH
• dospělí MeSH
• epilepsie terapie   MeSH
• komunikace * MeSH
• kvalita života MeSH
• lidé středního věku MeSH
• lidé MeSH
• management nemoci MeSH
• mladý dospělý MeSH
• pacientův souhlas se zdravotní péčí * MeSH
• postoj ke zdraví MeSH
• self-management * MeSH
• telemedicína * MeSH
• vztahy mezi lékařem a pacientem * MeSH
• záchvaty MeSH
• zakotvená teorie MeSH
• zapojení pacienta MeSH
• zjišťování skupinových postojů MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Itálie MeSH
• Španělsko MeSH
• Spojené království MeSH

• Klíčová slova
• hovězí maso, intramuskulární tuk,
• MeSH
• červené maso * analýza   MeSH
• chuť MeSH
• dietní tuky MeSH
• dobytek MeSH
• lidé MeSH
• maso statistika a číselné údaje   MeSH
• nutriční hodnota MeSH
• preference v jídle * MeSH
• průzkumy a dotazníky MeSH
• vaření metody   MeSH
• Check Tag
• lidé MeSH

• MeSH
• nitroděložní antikoncepční prostředky MeSH
• vypuzení nitroděložního tělíska MeSH
• Publikační typ
• časopisecké články MeSH

• Konspekt
• Gynekologie. Porodnictví
• NLK Obory
• gynekologie a porodnictví

Political action can reduce introductions of diseases caused by invasive forest pathogens (IPs) and public support is important for effective prevention. The public's awareness of IP problems and the acceptability of policies aiming to combat these pathogens were surveyed in nine European countries (N = 3469). Although awareness of specific diseases (e.g., ash dieback) varied, problem awareness and policy acceptability were similar across countries. The public was positive towards policies for informational measures and stricter standards for plant production, but less positive towards restricting public access to protected areas. Multilevel models, including individual and country level variables, revealed that media exposure was positively associated with awareness of IP problems, and strengthened the link between problem awareness and policy acceptability. Results suggest that learning about IPs through the media and recognizing the associated problems increase policy acceptability. Overall, the study elaborates on the anthropogenic dimension of diseases caused by IPs.

• MeSH
• lesy * MeSH
• postup * MeSH
• průzkumy a dotazníky MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Evropa MeSH

• MeSH
• antikoncepce metody   využití   MeSH
• cervikální hlen fyziologie   MeSH
• metody přirozeného plánování rodičovství MeSH
• plodné dny fyziologie   MeSH
• rodičovství MeSH
• určení ovulace metody   využití   MeSH
• ženy psychologie   MeSH
• změny tělesné teploty MeSH

• Konspekt
• Hygiena. Lidské zdraví
• NLK Obory
• reprodukční lékařství
• NLK Publikační typ
• studie